Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P50502 (Hip)
7,003 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Gait analysis in orthopaedic and neurological examinations is important; however, few studies assess gait variability at different walking speeds in patients with varying degrees of hip osteoarthritis. We aimed to clarify (1) how different controlled speeds and (2) various severities of hip osteoarthritis influence gait variability. Gait variability was described by the standard deviation (SD) of the spatial-temporal and mean standard deviation (MeanSD) of angular parameters. The spatial positions of the anatomical points for calculating gait parameters were determined in 20 healthy elderly controls and 20 patients with moderate and 20 patients with severe hip osteoarthritis with a zebris CMS-HS ultrasound-based motion analysis system at three walking speeds. The SD of the spatial-temporal and MeanSD of angular parameters of gait, which together describe gait variability, significantly depended on speed and osteoarthritis severity. The lowest variability in the gait was found near the self-selected walking speeds. Hip joint degeneration significantly worsened variability on the affected side, with non-affected joints and the pelvis compensating by increasing flexibility and adapting to step-by-step motions. Particular attention must be paid to improving gait stability and the reliability of limb movements in the presence of and increasing severity of osteoarthritis.
...
PMID:Effect of walking speed and severity of hip osteoarthritis on gait variability. 2082 18

We hypothesized that the Centers for Medicare and Medicaid Services Limited Dataset (CMS-LDS) could be used to validate the complications associated with total hip and knee arthroplasty (THA and TKA) endorsed by the Hip and Knee Societies. Using ICD-9 procedure and diagnosis codes, cases were extracted from the first three quarters of the 2009 CMS-LDS to allow all complications within 90-days be captured in the same calendar year. We were unable to validate the Hip and Knee Societies' complications as we could not connect readmissions or outpatient visits to index admissions. In addition, well-known complications were not detected, raising concerns about coding accuracy and stratification. Furthermore, the assignment of outpatient and inpatient codes allows for duplication of complications which may falsely elevate the true incidence.
...
PMID:Can Administrative Data Be Used to Analyze Complications Following Total Joint Arthroplasty? 2618 86

This editorial reviews the recently published study (AJMC April) by Gerrard et al, titled "Functional Status and Readmissions in Unilateral Hip Fractures," which analyzes the statistical prediction model of the Fitness Index Measure for hospital readmission in unilateral hip fractures, and discusses why functional assessment should be used in evaluating other conditions. The current method of stratifying risk for Core Measure Conditions used by CMS to predict hospital readmissions utilizes a largely nonmodifiable formula of age, gender, and medical comorbidities. Numerous recent studies have shown that validated functional assessment can be a powerful statistical predictor of hospital readmission. The author makes the argument for CMS to utilize functional assessment to predict hospital readmissions as a part of its Value-Based Purchasing Program.
...
PMID:It's time for CMS to utilize functional assessment as a key quality component. 2629 74