Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P47989 (xanthine oxidase)
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Human Gene/Protein
xanthine oxidase 11.8
EVI-5 11.8
CYPIIIA4 10.8
xanthine dehydrogenase 10.8
2P domain potassium channel 10.3
XDH 10.2
nuclear prelamin A recognition factor 9.8
CT39 9.8
SAPK-interacting protein 1 9.8
IOP2 9.8
urate transporter 1 9.8
aldehyde oxidase 9.7
xanthine oxidoreductase 9.6
Aldehyde oxidase 1 9.5
Butyrophilin 9.1
GLUT9 9.1
TALK-1 8.9
Ras and Rab interactor 1 8.8
Myosin light chain 1 8.8
nucleoside phosphorylase 8.7
gamma-Butyrobetaine hydroxylase 8.7
H2B.2 8.7
butyrophilin 8.6
alanine-glyoxylate aminotransferase 2 8.5
sulfite oxidase 8.5
guanine deaminase 8.5
molybdenum cofactor sulfurase 8.5
IMPD 8.4
GTF2H1 8.4
arylformamidase 8.4
Neuronal protein 8.4
POLD2 8.4
anion transporter 1 8.4
C6orf4 8.4
Allantoicase 8.3
IOP1 8.3
phosphoribosyl pyrophosphate amidotransferase 8.3
DCTN2 8.3
Guanase 8.3
organic anion transporter 1 8.2
SEPW1 8.2
MT1R 8.1
aldehyde oxidase 1 8.1
guanine aminohydrolase 8.0
carboxypeptidase B1 8.0
NAD(+) kinase 8.0
GTK 8.0
Ferroxidase 8.0
NOT 8.0
Superoxide dismutase 7.9
TALK-2 7.8
transmembrane transport protein 7.7
PLA2G3 7.6
HMOX2 7.5
N-acetyltransferase 2 7.5
Ubiquitin carboxy-terminal hydrolase 7.5
DUSP16 7.5
RST 7.4
LZP 7.3
PAPA 7.2
GPR142 7.2
Catalase 7.2
TXN 7.1
organic anion transporter 4 7.1
Sulfite oxidase 7.1
histone deacetylase 11 7.1
purine nucleoside phosphorylase 7.1
hCNT2 7.1
FADH2 7.1
TMX 7.1
TIPARP 7.0
MOCS3 7.0
peroxiredoxin 4 7.0
OAT1 7.0
superoxide dismutase 7.0
JNK-interacting protein 3 7.0
sulfonylurea receptor 2 6.9
extracellular superoxide dismutase 6.9
heart protein 6.9
GST-1 6.8
more...
Disease
Chronic clonorchiasis 11.8
Xanthine oxidase deficiency 10.6
Molybdenum deficiency 10.3
Xanthinuria 9.4
Yoshida Sarcoma 9.0
Sulfite oxidase deficiency 8.5
hyperuricemia 8.5
APRT deficiency 8.3
Acute gouty arthritis 8.3
Spinal cord atrophy 8.3
streptoccocal 8.3
gout 8.1
Gouty arthritis 8.0
histiocytic leukemia 7.7
tophi 7.6
Recurrent herpes labialis 7.6
Mammary adenocarcinoma 7.5
podagra 7.5
ADSA 7.1
PAPA 7.0
uricosuria 7.0
Disuse atrophy 6.7
Molybdenum cofactor deficiency 6.6
renin-dependent hypertension 6.4
CG3 6.4
ADA deficiency 6.3
Exertional rhabdomyolysis 6.3
tumor lysis syndrome 6.1
FBD 6.1
ALS2 5.9
Rotavirus gastroenteritis 5.8
diabetic cataract 5.7
Harley 5.7
Lesch-Nyhan syndrome 5.6
PNP deficiency 5.6
hepatic echinococcosis 5.6
renal ischemia 5.6
Intestinal ischemia 5.5
alcoholic cardiomyopathy 5.5
VDI 5.4
Oxygen toxicity 5.3
PMS 5.2
Acute myocardial ischemia 5.2
Lowe 5.2
Chronic mountain sickness 5.2
acute arthritis 5.2
Acute pyelonephritis 5.1
gastric lesion 5.1
Myocardial necrosis 5.1
DRESS syndrome 5.0
Postinfarction 5.0
hemoglobinemia 5.0
GSH 4.9
ischemia 4.8
furuncle 4.8
Pfeiffer 4.7
Transient ischemia 4.6
Carotid body 4.6
Carotid body 4.6
Carotid body 4.6
Acute mesenteric ischemia 4.6
Endothelial dysfunction 4.6
LGM 4.5
chronic granulomatous disease 4.5
Spinal cord ischemia 4.4
nephrosis 4.4
Diaphragm 4.4
UIP 4.4
Bianchi 4.3
hyperoxaluria 4.3
LPI 4.3
Testicular torsion 4.3
complicated pregnancy 4.2
McArdle's disease 4.2
urolithiasis 4.2
Insulinoma 4.2
rheumatism 4.2
tubular necrosis 4.2
Spontaneous bacterial peritonitis 4.1
Dupuytren 4.1
more...
Symptom
Macula 5.0
autodigestion 4.5
hyperoxia 4.4
throat irritation 4.4
Anoxia 4.3
catarrh 4.3
skin damage 4.1
disturbed balance 4.0
athetosis 3.8
No adverse effect 3.5
prostration 3.3
hyperesthesia 2.8
ketonuria 2.7
oliguria 2.6
leg edema 2.5
renal colic 2.2
rigors 2.2
hypocapnia 2.1
twitching 1.9
functional recovery 1.8
eds 1.8
muscle rigidity 1.8
exhaustion 1.7
hypertonia 1.6
dry eye 1.5
tonic-clonic seizure 1.5
colic 1.2
hypothermia 1.1
neuralgia 1.1
angina 1.1
respiratory distress 1.0
cachexia 1.0
skin irritation 0.8
myalgia 0.8
acute stress 0.7
arthralgia 0.6
starvation 0.6
acidity 0.5
erythema 0.5
hypercapnia 0.5
asthenia 0.5
HSA 0.3
polyuria 0.3
flushing 0.2
dizziness 0.2
fatigue 0.2
exertional dyspnea 0.1
memory loss 0.0
pelvic pain -0.1
anesthesia -0.2
hepatosplenomegaly -0.3
seizures -0.3
nausea -0.3
diarrhea -0.4
Ill -0.6
thinning -0.6
collapse -0.6
paresis -0.7
hypotonia -0.7
agitation -0.7
vomiting -0.8
anorexia -0.9
spasm -1.0
weakness -1.0
dystonia -1.2
chest pain -1.2
overweight -1.3
pain -1.6
discomfort -1.6
headache -1.6
discomfort -1.7
sleepiness -1.8
abdominal pain -2.1
Drug
Dezaguanine 11.8
Amflutizole 11.8
Y-700 11.2
Febuxostat 10.9
Desciclovir 10.3
Fenazox 10.3
Lodoxamide tromethamine 9.7
Guanoxabenz 9.5
Chrysanthemum flower 9.5
Fudosteine 9.3
Troxipide 9.3
Succinobucol 8.8
Angelica dahurica root 8.7
Atractylodes rhizome 8.7
Gefarnate 8.7
Bupleurum root 8.7
Moco 8.5
Pinellia tuber 8.5
Scutellaria root 8.5
Tantum 8.0
Nadifloxacin 8.0
Maribavir 7.9
7,8-Dihydroneopterin 7.8
Argininosuccinate 7.8
Rasburicase 7.7
Desferal 7.7
Bendazac 7.6
Rasburicase 7.6
TMX 7.6
Desferal 7.6
Pentastarch 7.5
Plaunotol 7.5
Nitecapone 7.4
Sesame oil 7.3
Tanespimycin 7.3
Oxyphenbutazone 7.3
Oxyphenbutazone 7.2
Caraway 7.1
Lisofylline 7.1
Orgotein 7.0
Rebamipide 6.9
Zinc sulfate 6.9
Acadesine 6.9
Zinc sulfate 6.9
Bicine 6.8
Sulfaphenazole 6.8
Malonaldehyde 6.8
Teduglutide 6.7
Bucillamine 6.6
Mercaptopurine 6.5
NBT 6.5
Ponalrestat 6.5
Sodium metabisulfite 6.4
Tirapazamine 6.4
1-Deoxynojirimycin 6.2
Myricetin 6.2
Lantus 6.1
Tenidap 6.1
Pancreatin 6.0
Sesamol 6.0
Sulla 5.9
Nafamostat mesilate 5.9
FAD 5.8
Jujube 5.7
Nilvadipine 5.7
Adenosine deaminase 5.6
Hakka 5.5
Cicletanine 5.5
Dazoxiben 5.4
Compound 19 5.4
NADH 5.4
Cilnidipine 5.4
Zovirax 5.3
Nabumetone 5.2
FeCl3 5.2
ascorbate 5.1
Ulinastatin 5.0
FCV 5.0
Pirfenidone 5.0
Lutalyse 4.9
more...
Enzyme
xanthine oxidase 11.8
xanthine dehydrogenase 10.4
guanosine phosphorylase 10.3
isoquinoline 1-oxidoreductase 9.8
aldehyde oxidase 9.7
4-hydroxybenzoyl-CoA reductase 9.5
quinoline 2-oxidoreductase 9.4
melilotate hydroxylase 9.3
pyrimidine deoxyribonucleoside 2'-hydroxylase 9.3
nicotinic acid hydroxylase 9.2
guanase 9.0
FAEES 8.8
allantoicase 8.6
guanosine deaminase 8.5
sulfite oxidase 8.5
sulfite oxidase 8.4
histolysain 8.4
uricase 8.3
allantoate amidohydrolase 8.2
pyridoxal oxidase 8.1
thymine 7-hydroxylase 7.8
retinal oxidase 7.8
amidophosphoribosyltransferase 7.5
allantoinase 7.5
indole 2,3-dioxygenase 7.5
2-nitropropane dioxygenase 7.5
EC 1.3.2.3 7.3
aldehyde dehydrogenase 7.2
NADPH oxidase 7.1
purine nucleoside phosphorylase 7.1
NADPH oxidase 7.0
superoxide reductase 6.9
superoxide dismutase 6.9
formylmethanofuran dehydrogenase 6.8
octanol dehydrogenase 6.7
putrescine oxidase 6.6
CO dehydrogenase 6.6
glucose oxidase 6.6
catalase 6.5
DHOdehase 6.5
kynurenine formamidase 6.5
prostacyclin synthase 6.4
adenosine deaminase 6.4
adenosine deaminase 6.4
D-amino acid aminotransferase 6.4
p-cresol methylhydroxylase 6.3
glycine reductase 6.2
thiopurine methyltransferase 6.2
GMP reductase 6.1
GMP synthase 6.1
glutathione peroxidase 6.0
glycolate dehydrogenase 6.0
benzoate dioxygenase 6.0
adenine phosphoribosyltransferase 5.9
deoxyhypusine hydroxylase 5.8
NADH-cytochrome b5 reductase 5.8
nucleoside hydrolase 5.8
AMP deaminase 5.7
adenylosuccinate synthetase 5.7
lipoxygenase 5.7
cytochrome b6/f complex 5.7
lactate oxidase 5.6
pseudolysin 5.6
GMP synthetase 5.6
hypoxanthine-guanine phosphoribosyltransferase 5.6
glutathione reductase 5.6
cysteine conjugate beta-lyase 5.6
histidase 5.6
choline dehydrogenase 5.6
myo-inositol oxygenase 5.5
CMP kinase 5.5
ferredoxin reductase 5.5
gamma-butyrobetaine hydroxylase 5.5
trimethylamine dehydrogenase 5.5
nitrate reductase 5.4
nitrate reductase 5.4
NQO1 5.4
nitrate reductase 5.4
nitrate reductase 5.3
nitrate reductase 5.3
more...
Compound
1,7-dihydropyrano[4,3-b]pyrrole-4,6-dione 11.8
1H-pyrrolo[3,2-c]pyridine-4,6(5H,7H)-dione 11.8
2-Amino-6-chloropurine 11.8
Afzelechin 11.8
S-Methylisothiourea sulfate 11.8
4-Hydroxypteridine 11.8
6-(chloromethyl)-9H-purine 11.8
Colchizin 11.8
Oxypurinol 10.9
2-hydroxy-6-pentadecylbenzoic acid 10.8
2-naphthyl laurate 10.8
N-phenylisonicotinamide 10.8
Jacareubin 10.8
1-chlorophthalazine 10.8
3,5-dichloro-2-hydroxybenzenesulfonic acid 10.5
C15H10O7 10.3
C15H10O7 10.3
ethyl undecanoate 10.3
C15H10O7 10.3
4-chloro-7H-pyrrolo[2,3-d]pyrimidine 10.3
C14H8N4O6 10.3
C15H10O7 10.3
Urothione 10.3
C9H13N3O5 10.3
Xanthine 10.2
2-phenyl-1H-imidazole 10.1
Cardol 9.8
Benziodarone 9.8
Luteolin 7-O-glucoside 9.8
C8H8O3 9.8
sebacamide 9.8
Tinoridine 9.8
Pedalitin 9.8
C20H24O6 9.8
C15H10O7 9.8
C15H10O7 9.8
HPP 9.8
Purpurogallin 9.8
stearaldehyde 9.5
C15H10O7 9.5
3-hydroxy-4-methoxybenzaldehyde 9.3
Rubrofusarin 9.3
2-quinoxalinecarboxamide 9.3
Aldophosphamide 9.3
Hypoxanthine 9.2
Lithospermic acid 9.1
Balofloxacin 9.0
Rubrofusarin 9.0
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one 9.0
AFMU 8.9
Panaxatriol 8.8
3-Deazaguanine 8.8
Robinetin 8.8
N-hydroxyguanidine 8.8
Norathyriol 8.8
Scopolin 8.7
3-Methylxanthine 8.7
o-Nitroanisole 8.7
Potassium oxonate 8.7
2,3,4-trihydroxybenzoic acid 8.7
2-Nitrofluorene 8.7
Panaxadiol 8.5
5-phenylisoxazole 8.5
Hypolaetin 8.5
Isovitexin 8.5
Benzbromarone 8.5
Coformycin 8.5
C30H50 8.4
Gossypin 8.4
Isoorientin 8.3
Dynemicin A 8.3
1-phenyl-1H-1,2,3-triazole 8.3
Molybdenum cofactor 8.3
4000 M 8.2
Tricetin 8.1
13(S)-HPODE 8.1
Uric acid 8.1
superoxide radical 8.1
Phorone 8.1
1-Nitropyrene 8.1
more...