Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P47989 (
xanthine oxidase
)
8,633
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
xanthine oxidase
8633
superoxide dismutase
1695
catalase
1335
Sep
624
xanthine dehydrogenase
403
glutathione peroxidase
385
Mol
334
GSH
308
SOD
279
nitric oxide synthase
277
NADPH
275
ATP
254
NADH
249
myeloperoxidase
235
cytochrome c
216
Superoxide dismutase
191
lactate dehydrogenase
188
aldehyde oxidase
180
cyclooxygenase
167
peroxidase
162
microsomal
153
Catalase
141
NAD
140
tumor necrosis factor
125
glutathione reductase
122
lipoxygenase
120
NMR
120
lipopolysaccharide
118
adenosine deaminase
118
albumin
113
xanthine oxidoreductase
111
ROS
110
ADP
108
inducible nitric oxide synthase
99
ATPase
98
insulin
96
EPR
92
cytochrome P450
91
TNF
86
cytokine
85
FAD
84
reductase
83
AMP
73
antioxidant enzyme
73
collagen
71
caspase-3
69
cytochrome P-450
67
ESR
65
serum albumin
65
cytochrome
63
hemoglobin
63
alkaline phosphatase
60
XDH
58
purine nucleoside phosphorylase
57
oxidoreductase
56
aspartate aminotransferase
56
NOT
55
NAD+
55
gut
54
IL-6
51
MnSOD
51
angiotensin II
51
endothelial nitric oxide synthase
50
glucose-6-phosphate dehydrogenase
49
thymus
48
p38
47
tyrosinase
47
TNF-alpha
46
vascular endothelium
46
ornithine decarboxylase
46
spermatozoa
46
ferritin
45
heme oxygenase-1
45
phospholipase A2
45
endoplasmic reticulum
44
amylase
43
CO2
43
sulfite oxidase
43
glutathione S-transferase
41
flavoprotein
41
more...
Disease
ischemia
695
gout
380
hyperuricemia
365
GSH
308
cancer
274
diabetes
191
hypertension
189
tumor
177
atherosclerosis
137
heart failure
98
arthritis
89
cardiovascular disease
81
depression
79
myocardial ischemia
76
carcinogenesis
74
myocardial infarction
59
renal disease
57
NAME
56
stroke
53
obesity
52
cerebral ischemia
50
sepsis
46
cold
45
sepsis
44
hyperglycemia
43
metabolic syndrome
42
hypercholesterolemia
40
Alzheimer's disease
39
SDS
38
acute pancreatitis
38
carcinoma
37
type 2 diabetes
33
renal ischemia
32
pulmonary edema
32
SEM
32
pancreatitis
31
hepatocellular carcinoma
28
renal failure
26
tophi
26
pulmonary hypertension
24
leukemia
24
vascular disease
24
acute myocardial infarction
22
plaque
22
preeclampsia
22
hepatitis
21
rheumatoid arthritis
21
hyperlipidemia
20
urolithiasis
20
adult respiratory distress syndrome
20
asthma
19
breast cancer
19
acute renal failure
19
melanoma
19
proteinuria
19
mole
19
mole
19
immunodeficiency
19
renal impairment
19
congestive heart failure
18
coronary artery disease
18
Parkinson's disease
18
influenza
18
malaria
17
chronic granulomatous disease
16
renal insufficiency
15
tumorigenesis
15
HIV
14
tumor lysis syndrome
14
virus infection
14
inflammatory bowel disease
14
prostate cancer
14
rheumatism
14
MCF
14
ulcerative colitis
13
diabetic nephropathy
13
tuberculosis
13
colitis
13
metabolic disorder
13
ventricular fibrillation
13
more...
Symptom
hyperoxia
30
anesthesia
26
pain
24
seizures
18
fatigue
16
functional recovery
13
angina
12
diarrhea
12
exhaustion
12
respiratory distress
11
hypothermia
10
starvation
10
skin damage
7
acidity
6
collapse
5
nausea
5
vomiting
5
weakness
5
erythema
5
headache
5
hypercapnia
3
overweight
3
oliguria
3
arthralgia
3
Anoxia
3
dizziness
3
myalgia
3
cachexia
3
Ill
2
hypocapnia
2
flushing
2
discomfort
2
anorexia
2
discomfort
2
twitching
2
chest pain
2
abdominal pain
2
colic
2
agitation
2
autodigestion
2
dry eye
2
acute stress
2
thinning
2
memory loss
1
skin irritation
1
pelvic pain
1
polyuria
1
tonic-clonic seizure
1
asthenia
1
hypertonia
1
hypotonia
1
renal colic
1
prostration
1
muscle rigidity
1
hepatosplenomegaly
1
exertional dyspnea
1
leg edema
1
athetosis
1
HSA
1
neuralgia
1
paresis
1
eds
1
No adverse effect
1
spasm
1
rigors
1
catarrh
1
ketonuria
1
disturbed balance
1
sleepiness
1
throat irritation
1
Macula
1
hyperesthesia
1
dystonia
1
Drug
NADH
247
ascorbate
213
vitamin E
135
ROS
110
FAD
84
Cardiovasc
84
Febuxostat
76
caffeine
71
Indomethacin
33
NBT
32
Dermatol
32
Ethanol
27
lysine
26
Glutathione
24
Vitamin E
19
nitroglycerin
17
IFN-gamma
15
Adriamycin
15
Desferal
14
FeCl3
14
Desferal
14
Rasburicase
13
Albumin
12
Mutagen
11
CaCl2
10
CaCl2
10
Nitric Oxide
10
Gel
10
CaCl2
10
Adenosine deaminase
9
Ringer's solution
9
CSF
9
Methylene blue
9
L-tyrosine
9
Leaf
8
IL-2
8
Monit
8
Angiotensin II
8
Nephron
8
Acacia
7
MAP
7
Vitamin K
7
balanced salt solution
7
Y-700
7
Propofol
6
Fructose
6
Nephron
6
Spectrum
6
Sodium nitroprusside
6
Captopril
6
Myricetin
6
Photofrin
6
Cimetidine
5
BH4
5
Rebamipide
5
Rasburicase
5
NH3
5
pyridoxal phosphate
5
Fluorescein
5
Arsenic trioxide
5
Rutin
5
Cimetidine
5
Glycyrrhiza
5
Omeprazole
4
Aloe
4
Ouabain
4
Heme
4
CTX
4
Histamine
4
CAM
4
ETA
4
ZnO
4
DNase I
4
TMX
4
TiO2
3
MgSO4
3
ICI
3
Moco
3
Fraction
3
APD
3
more...
Enzyme
xanthine oxidase
7867
superoxide dismutase
1868
catalase
1347
xanthine dehydrogenase
459
NADPH oxidase
432
peroxidase
400
glutathione peroxidase
392
NADPH oxidase
352
aldehyde dehydrogenase
210
lactate dehydrogenase
202
aldehyde oxidase
171
glucose oxidase
138
NO synthase
124
glutathione reductase
123
lipoxygenase
121
adenosine deaminase
119
adenosine deaminase
118
ATPase
109
uricase
103
mitogen-activated protein kinase
93
protein kinase C
87
NQO1
70
aspartate aminotransferase
67
alanine aminotransferase
65
alkaline phosphatase
60
glutathione S-transferase
59
phospholipase A2
59
creatine kinase
58
glucose-6-phosphate dehydrogenase
54
caspase-3
53
diaphorase
53
purine nucleoside phosphorylase
53
tyrosinase
49
aldehyde dehydrogenase
49
ornithine decarboxylase
46
CPR
44
NOS
44
sulfite oxidase
44
sulfite oxidase
43
protein kinase
42
nitrate reductase
42
complex I
42
nitrate reductase
42
nitrate reductase
42
nitrate reductase
42
nitrate reductase
41
nitrate reductase
41
trypsin
40
monoamine oxidase
40
alcohol dehydrogenase
39
elastase
39
aldehyde dehydrogenase
38
aldehyde dehydrogenase
38
aldehyde dehydrogenase
38
5'-nucleotidase
34
guanylate cyclase
33
guanase
33
hypoxanthine-guanine phosphoribosyltransferase
33
succinate dehydrogenase
30
gamma-glutamyl transpeptidase
29
collagenase
28
ceruloplasmin
28
ERK
28
renin
27
acetylcholinesterase
26
heme oxygenase
24
diaphorase
23
NADPH-diaphorase
23
ACE
23
N-acetyltransferase
22
phosphodiesterase
22
lipase
21
thrombin
18
NADH dehydrogenase
18
ACS
17
cytochrome oxidase
17
alpha-glucosidase
16
PARP
16
phospholipase C
16
aconitase
16
more...
Compound
oxygen
2908
hydrogen
965
H2O2
798
nitric oxide
624
Dec
606
iron
575
DNA
561
superoxide radical
465
sodium
400
water
389
calcium
372
Clin
367
HPP
345
GSH
334
GSH
334
molybdenum
313
glucose
301
NADPH
275
NADPH
275
phosphate
263
ATP
254
acetate
249
NADH
247
nitrogen
245
ethanol
240
arginine
198
aldehyde
196
potassium
190
NAD
188
copper
183
cysteine
172
EDTA
146
EDTA
144
creatinine
141
NAD
140
DPPH
132
acetaldehyde
124
ADP
124
urea
122
nicotinamide
120
Xanthine
112
Uric acid
108
ADP
108
ADP
108
sulfate
102
methanol
95
zinc
95
salt
94
CO2
92
aldehyde
91
Cardiol
90
tyrosine
89
nitrate
87
cyanide
87
TNF
86
DMSO
86
FAD
84
N-acetylcysteine
76
ethyl acetate
72
manganese
72
PEG
72
tungsten
71
Phe
71
caffeine
71
GSSG
69
MDA
66
pyrimidine
65
pyrimidine
65
AMP
64
glutamate
64
Hypoxanthine
60
methionine
56
ammonium
56
galactose
56
hydroxide
55
chromate
55
prostacyclin
50
His
50
selenium
49
iodine
47
more...