Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P47989 (xanthine oxidase)
8,633 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
xanthine oxidase 8633
superoxide dismutase 1695
catalase 1335
Sep 624
xanthine dehydrogenase 403
glutathione peroxidase 385
Mol 334
GSH 308
SOD 279
nitric oxide synthase 277
NADPH 275
ATP 254
NADH 249
myeloperoxidase 235
cytochrome c 216
Superoxide dismutase 191
lactate dehydrogenase 188
aldehyde oxidase 180
cyclooxygenase 167
peroxidase 162
microsomal 153
Catalase 141
NAD 140
tumor necrosis factor 125
glutathione reductase 122
lipoxygenase 120
NMR 120
lipopolysaccharide 118
adenosine deaminase 118
albumin 113
xanthine oxidoreductase 111
ROS 110
ADP 108
inducible nitric oxide synthase 99
ATPase 98
insulin 96
EPR 92
cytochrome P450 91
TNF 86
cytokine 85
FAD 84
reductase 83
AMP 73
antioxidant enzyme 73
collagen 71
caspase-3 69
cytochrome P-450 67
ESR 65
serum albumin 65
cytochrome 63
hemoglobin 63
alkaline phosphatase 60
XDH 58
purine nucleoside phosphorylase 57
oxidoreductase 56
aspartate aminotransferase 56
NOT 55
NAD+ 55
gut 54
IL-6 51
MnSOD 51
angiotensin II 51
endothelial nitric oxide synthase 50
glucose-6-phosphate dehydrogenase 49
thymus 48
p38 47
tyrosinase 47
TNF-alpha 46
vascular endothelium 46
ornithine decarboxylase 46
spermatozoa 46
ferritin 45
heme oxygenase-1 45
phospholipase A2 45
endoplasmic reticulum 44
amylase 43
CO2 43
sulfite oxidase 43
glutathione S-transferase 41
flavoprotein 41
more...
Disease
ischemia 695
gout 380
hyperuricemia 365
GSH 308
cancer 274
diabetes 191
hypertension 189
tumor 177
atherosclerosis 137
heart failure 98
arthritis 89
cardiovascular disease 81
depression 79
myocardial ischemia 76
carcinogenesis 74
myocardial infarction 59
renal disease 57
NAME 56
stroke 53
obesity 52
cerebral ischemia 50
sepsis 46
cold 45
sepsis 44
hyperglycemia 43
metabolic syndrome 42
hypercholesterolemia 40
Alzheimer's disease 39
SDS 38
acute pancreatitis 38
carcinoma 37
type 2 diabetes 33
renal ischemia 32
pulmonary edema 32
SEM 32
pancreatitis 31
hepatocellular carcinoma 28
renal failure 26
tophi 26
pulmonary hypertension 24
leukemia 24
vascular disease 24
acute myocardial infarction 22
plaque 22
preeclampsia 22
hepatitis 21
rheumatoid arthritis 21
hyperlipidemia 20
urolithiasis 20
adult respiratory distress syndrome 20
asthma 19
breast cancer 19
acute renal failure 19
melanoma 19
proteinuria 19
mole 19
mole 19
immunodeficiency 19
renal impairment 19
congestive heart failure 18
coronary artery disease 18
Parkinson's disease 18
influenza 18
malaria 17
chronic granulomatous disease 16
renal insufficiency 15
tumorigenesis 15
HIV 14
tumor lysis syndrome 14
virus infection 14
inflammatory bowel disease 14
prostate cancer 14
rheumatism 14
MCF 14
ulcerative colitis 13
diabetic nephropathy 13
tuberculosis 13
colitis 13
metabolic disorder 13
ventricular fibrillation 13
more...
Symptom
hyperoxia 30
anesthesia 26
pain 24
seizures 18
fatigue 16
functional recovery 13
angina 12
diarrhea 12
exhaustion 12
respiratory distress 11
hypothermia 10
starvation 10
skin damage 7
acidity 6
collapse 5
nausea 5
vomiting 5
weakness 5
erythema 5
headache 5
hypercapnia 3
overweight 3
oliguria 3
arthralgia 3
Anoxia 3
dizziness 3
myalgia 3
cachexia 3
Ill 2
hypocapnia 2
flushing 2
discomfort 2
anorexia 2
discomfort 2
twitching 2
chest pain 2
abdominal pain 2
colic 2
agitation 2
autodigestion 2
dry eye 2
acute stress 2
thinning 2
memory loss 1
skin irritation 1
pelvic pain 1
polyuria 1
tonic-clonic seizure 1
asthenia 1
hypertonia 1
hypotonia 1
renal colic 1
prostration 1
muscle rigidity 1
hepatosplenomegaly 1
exertional dyspnea 1
leg edema 1
athetosis 1
HSA 1
neuralgia 1
paresis 1
eds 1
No adverse effect 1
spasm 1
rigors 1
catarrh 1
ketonuria 1
disturbed balance 1
sleepiness 1
throat irritation 1
Macula 1
hyperesthesia 1
dystonia 1
Drug
NADH 247
ascorbate 213
vitamin E 135
ROS 110
FAD 84
Cardiovasc 84
Febuxostat 76
caffeine 71
Indomethacin 33
NBT 32
Dermatol 32
Ethanol 27
lysine 26
Glutathione 24
Vitamin E 19
nitroglycerin 17
IFN-gamma 15
Adriamycin 15
Desferal 14
FeCl3 14
Desferal 14
Rasburicase 13
Albumin 12
Mutagen 11
CaCl2 10
CaCl2 10
Nitric Oxide 10
Gel 10
CaCl2 10
Adenosine deaminase 9
Ringer's solution 9
CSF 9
Methylene blue 9
L-tyrosine 9
Leaf 8
IL-2 8
Monit 8
Angiotensin II 8
Nephron 8
Acacia 7
MAP 7
Vitamin K 7
balanced salt solution 7
Y-700 7
Propofol 6
Fructose 6
Nephron 6
Spectrum 6
Sodium nitroprusside 6
Captopril 6
Myricetin 6
Photofrin 6
Cimetidine 5
BH4 5
Rebamipide 5
Rasburicase 5
NH3 5
pyridoxal phosphate 5
Fluorescein 5
Arsenic trioxide 5
Rutin 5
Cimetidine 5
Glycyrrhiza 5
Omeprazole 4
Aloe 4
Ouabain 4
Heme 4
CTX 4
Histamine 4
CAM 4
ETA 4
ZnO 4
DNase I 4
TMX 4
TiO2 3
MgSO4 3
ICI 3
Moco 3
Fraction 3
APD 3
more...
Enzyme
xanthine oxidase 7867
superoxide dismutase 1868
catalase 1347
xanthine dehydrogenase 459
NADPH oxidase 432
peroxidase 400
glutathione peroxidase 392
NADPH oxidase 352
aldehyde dehydrogenase 210
lactate dehydrogenase 202
aldehyde oxidase 171
glucose oxidase 138
NO synthase 124
glutathione reductase 123
lipoxygenase 121
adenosine deaminase 119
adenosine deaminase 118
ATPase 109
uricase 103
mitogen-activated protein kinase 93
protein kinase C 87
NQO1 70
aspartate aminotransferase 67
alanine aminotransferase 65
alkaline phosphatase 60
glutathione S-transferase 59
phospholipase A2 59
creatine kinase 58
glucose-6-phosphate dehydrogenase 54
caspase-3 53
diaphorase 53
purine nucleoside phosphorylase 53
tyrosinase 49
aldehyde dehydrogenase 49
ornithine decarboxylase 46
CPR 44
NOS 44
sulfite oxidase 44
sulfite oxidase 43
protein kinase 42
nitrate reductase 42
complex I 42
nitrate reductase 42
nitrate reductase 42
nitrate reductase 42
nitrate reductase 41
nitrate reductase 41
trypsin 40
monoamine oxidase 40
alcohol dehydrogenase 39
elastase 39
aldehyde dehydrogenase 38
aldehyde dehydrogenase 38
aldehyde dehydrogenase 38
5'-nucleotidase 34
guanylate cyclase 33
guanase 33
hypoxanthine-guanine phosphoribosyltransferase 33
succinate dehydrogenase 30
gamma-glutamyl transpeptidase 29
collagenase 28
ceruloplasmin 28
ERK 28
renin 27
acetylcholinesterase 26
heme oxygenase 24
diaphorase 23
NADPH-diaphorase 23
ACE 23
N-acetyltransferase 22
phosphodiesterase 22
lipase 21
thrombin 18
NADH dehydrogenase 18
ACS 17
cytochrome oxidase 17
alpha-glucosidase 16
PARP 16
phospholipase C 16
aconitase 16
more...
Compound
oxygen 2908
hydrogen 965
H2O2 798
nitric oxide 624
Dec 606
iron 575
DNA 561
superoxide radical 465
sodium 400
water 389
calcium 372
Clin 367
HPP 345
GSH 334
GSH 334
molybdenum 313
glucose 301
NADPH 275
NADPH 275
phosphate 263
ATP 254
acetate 249
NADH 247
nitrogen 245
ethanol 240
arginine 198
aldehyde 196
potassium 190
NAD 188
copper 183
cysteine 172
EDTA 146
EDTA 144
creatinine 141
NAD 140
DPPH 132
acetaldehyde 124
ADP 124
urea 122
nicotinamide 120
Xanthine 112
Uric acid 108
ADP 108
ADP 108
sulfate 102
methanol 95
zinc 95
salt 94
CO2 92
aldehyde 91
Cardiol 90
tyrosine 89
nitrate 87
cyanide 87
TNF 86
DMSO 86
FAD 84
N-acetylcysteine 76
ethyl acetate 72
manganese 72
PEG 72
tungsten 71
Phe 71
caffeine 71
GSSG 69
MDA 66
pyrimidine 65
pyrimidine 65
AMP 64
glutamate 64
Hypoxanthine 60
methionine 56
ammonium 56
galactose 56
hydroxide 55
chromate 55
prostacyclin 50
His 50
selenium 49
iodine 47
more...