Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P47989 (
xanthine oxidase
)
8,633
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Wistar rat myocardial cells were cultured.
PDS
20-80 micrograms.ml-1; PTS 1.25-20 micrograms.ml-1 dose-dependently decreased their action potential parameters, indicating the possibility of being concerned in the blockage of Ca channel. After the free radical damage was induced by xanthine 0.42 mmol.L-1--
xanthine oxidase
5.3 nmol.L-1 (X-XO). All the action potential parameters of the cardiac cells decreased without exception. Both PDA and PTS antagonized the electrical appearance of membrane damage induced by X-XO, suggesting that both
PDS
and PTS protect the myocardial cells from oxidative damage.
...
PMID:[Effects of panaxadiol and panaxatriol saponins on action potentials of normal and xanthine-xanthine oxidase damaged cultured myocardial cells]. 178 Dec 89
