Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P46098 (5-HT3 receptor)
 2,290 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
5-HT3E 13.8
5-HT3 receptor 13.8
5-HT3B 13.6
5-hydroxytryptamine4 receptor 12.8
HTR3D 12.8
HTR3C 12.4
HT3 12.3
HTR3E 12.0
HTR3A 11.7
HTR3B 11.6
5-HT3R 11.6
HTR3 11.5
ligand-gated ion channel subunit 11.4
ICS 11.4
5-HT4 receptor 11.4
5-HT4 11.1
CNIH2 10.8
5-HT2 receptor 10.6
ADRBK2 10.4
RIC-3 10.3
glycine receptor alpha 1 subunit 10.2
5-HT receptor 10.0
RIC3 10.0
5HT1a 9.9
MECR 9.9
5HT1A 9.8
5-HT7 9.6
5-HT5A 9.5
5-HT1B 9.5
BRL 9.4
5-HT6 9.4
5-HT1F 9.4
5-HT2A 9.4
Serotonin receptor 9.2
5-HT1D 9.2
5-HT1A 9.1
5-HT2C 9.0
ligand gated ion channel 8.7
5-hydroxytryptamine 8.7
serotonin receptor 8.6
GRIA4 8.5
K222 8.5
PKCI 8.3
5-HT2B 8.3
PBG 8.0
MEIS2 7.9
TPH1 7.9
MASP1 7.8
isoform a 7.6
Pannexin-1 7.6
P2X purinoceptor 7.6
Beta-galactosidase 7.6
NK1 7.5
Tph 7.5
GTS 7.4
Neuroserpin 7.4
SLC6A2 7.4
A2a adenosine receptor 7.4
PYY3 7.2
K81 7.2
ornithine transcarbamylase 7.2
TFL 7.1
RDL 7.1
CRHR2 7.1
SERT 7.1
NK3 receptor 7.1
CaCC 7.1
muscarinic M2 receptor 7.0
muscle nicotinic acetylcholine receptor 6.9
tryptophan hydroxylase 6.8
neurotransmitter receptor 6.8
AC8 6.8
nicotinic acetylcholine receptor 6.7
histamine H3 receptor 6.7
P31 6.6
NNH 6.5
GRK3 6.5
promyelocytic leukemia zinc finger 6.5
adenosine A2 receptor 6.5
Potassium channel 6.5
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Disease
Offensive aggression 12.8
Bezold 11.0
ICS 10.6
Bacterial gastroenteritis 10.6
Radiation esophagitis 10.2
functional diarrhea 9.0
psychoactive substance abuse 9.0
Erosive gastritis 8.1
stage IIIA NSCLC 7.4
motion sickness 7.2
irritable bowel syndrome 7.1
ischemic colitis 7.1
NNH 7.0
Microscopic colitis 6.9
classical migraine 6.9
Ileum 6.5
gastroparesis 6.5
DBA2 6.2
codependency 6.1
Marion 6.1
neurogenic hypertension 6.0
Akathisia 5.9
pica 5.9
diabetic hyperglycemia 5.9
Functional dyspepsia 5.9
periarthritis 5.8
vascular headache 5.8
SCH 5.7
Sexual dysfunction 5.7
Frey 5.6
obstipation 5.6
neuroblastoma 5.5
audiogenic seizure 5.5
carcinoid syndrome 5.4
anxiety state 5.4
fibromyalgia 5.4
OSX 5.3
Diabetic neuropathy 5.2
catalepsy 5.1
dumping syndrome 5.0
Opiates 5.0
gastrointestinal dysfunction 5.0
MEC 4.9
induced psychosis 4.8
cocaine abuse 4.8
GAD 4.8
inflammatory joint disease 4.7
panic attacks 4.5
Bradley 4.5
dyspepsia 4.5
NSD 4.4
Stomach 4.4
Stomach 4.4
Stomach 4.4
sexual dysfunction 4.3
Stomach 4.3
drug withdrawal 4.2
recurrent cancer 4.1
Wenckebach 4.1
antidiuresis 4.0
Hermansky-Pudlak syndrome 4.0
amnesia 3.9
migraine 3.9
LMS 3.9
drug abuse 3.9
hyperphagia 3.8
anxiety disorders 3.8
panic disorder 3.8
gynecologic cancer 3.8
Tourette syndrome 3.7
organic disease 3.7
PAL 3.7
fear and anxiety 3.6
alcoholism 3.6
disinhibition 3.6
carcinoid 3.6
PPP 3.6
Zollinger-Ellison syndrome 3.6
social phobia 3.6
memory impairment 3.5
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Symptom
Acute vomiting 12.4
Drug-induced vomiting 12.2
No vomiting 10.0
retching 9.4
Generalized pruritus 9.2
Postoperative nausea and vomiting 9.0
nausea and vomiting 8.6
Functional abdominal pain 8.3
Flu-like symptoms 8.0
Chronic abdominal pain 7.9
vomiting 7.4
Fluctuation 6.8
nausea 6.6
constipation 6.5
lightheadedness 6.3
catarrh 6.2
Extrapyramidal symptoms 6.2
disturbed balance 5.9
bloating 5.9
chronic constipation 5.4
No adverse effect 5.4
intention tremor 5.3
tenesmus 4.9
rundown 4.8
despair 4.7
abdominal discomfort 4.6
bitter taste 4.3
Neuropathic pain 4.3
diarrhea 4.1
analgesia 3.9
orofacial pain 3.9
anorexia 3.8
abdominal pain 3.7
discomfort 3.6
abnormal gait 3.6
decreased appetite 3.6
discomfort 3.5
acute pain 3.4
headache 3.4
Sedation 3.4
insomnia 3.2
dizziness 3.1
hypothermia 3.0
incoordination 3.0
sleepiness 2.9
hunger 2.9
pain 2.8
twitching 2.8
blurred vision 2.7
heartburn 2.7
vertigo 2.5
tachypnea 2.5
tremor 2.4
bone pain 2.2
fatigue 2.1
anesthesia 2.1
spasm 1.9
Ill 1.9
hypercapnia 1.8
agitation 1.8
pelvic pain 1.8
low back pain 1.5
hyperoxia 1.4
cachexia 1.3
flushing 1.1
seizures 0.9
ataxia 0.8
Welt 0.8
dystonia 0.7
syncope 0.6
angina 0.4
chest pain -0.3
cough -0.8
dyspnea -1.0
Drug
Pancopride 13.8
Serotone 13.8
Zatosetron maleate 13.8
Indisetron hydrochloride 13.8
FK 1052 13.2
Bemesetron 13.0
Ramosetron hydrochloride 13.0
Anzemet 12.6
Anzemet 12.6
Alosetron 12.4
Itasetron 12.2
Cilansetron 12.0
Navoban 11.9
Navoban 11.9
Palonosetron hydrochloride 11.7
Renzapride 11.5
Kytril 11.5
Kytril 11.4
Netupitant 10.9
Ezlopitant 10.6
Aprepitant 10.6
Tropinone 10.4
Zofran 10.3
Ipecac syrup 10.2
Zofran 9.5
Mosapride citrate 9.4
Ritanserin 9.4
Tegaserod 9.3
Tegaserod 9.2
Raloxifene 8.8
Reminyl 8.8
Namenda 8.6
Flesinoxan 8.4
Cisapride 8.4
Trimipramine 8.0
Loxiglumide 7.8
Mirtazapine 7.5
Tubocurarine 7.4
Domin 7.3
Moclobemide 7.2
Quinine, 7.1
Rifaximin 7.1
Aricept 7.0
DMAA 7.0
Estracyt 6.9
Fluphenazine 6.8
Dexfenfluramine 6.8
Estracyt 6.8
Menthol 6.5
Tianeptine 6.5
Scopolamine 6.4
Domperidone 6.4
Atomoxetine 6.1
Ginger 5.9
Atropine 5.8
Dihydro 5.7
Guanethidine 5.7
DHT 5.7
DHT 5.6
Ketotifen 5.6
K-252a 5.3
Modafinil 5.2
Cantor 5.2
ICI 4.7
Donepezil 4.7
GHRP 4.6
Ethanol 4.6
CDP 4.6
CFT 4.6
Budesonide 4.5
Rutin 4.4
Portal 4.3
9-THC 4.0
APD 3.9
DEX 3.9
CPT-11 3.9
GRF 3.8
Diphenhydramine 3.7
CTC 3.7
CTX 3.4
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Enzyme
endo-N 9.0
hydroxyprostaglandin dehydrogenase 7.1
tryptophan hydroxylase 6.9
6beta-hydroxylase 6.8
DMT 5.8
carbonyl reductase 5.7
ACAT 5.3
DAT 4.2
FAST 4.2
CYP3A4 4.1
TACE 4.1
dihydropyrimidine dehydrogenase 4.1
PHD 4.0
Rex 3.9
interstitial collagenase 3.9
lysin 3.7
DOPA decarboxylase 3.7
monoamine oxidase 3.7
glutamate decarboxylase 3.7
dihydropyrimidine dehydrogenase 3.5
adenylate cyclase 3.2
MAT 3.2
PAL 3.1
MAT 3.0
PCP 2.9
CaMKII 2.8
cholesterol acyltransferase 2.8
guanylate cyclase 2.7
PAL 2.7
aldehyde dehydrogenase 2.7
aldehyde dehydrogenase 2.7
aldehyde dehydrogenase 2.6
aldehyde dehydrogenase 2.4
phospholipase C 2.4
asparaginase 2.4
tyrosine hydroxylase 2.2
kallikrein 2.2
AST 2.2
aldehyde dehydrogenase 2.1
aldose reductase 2.1
protein kinase C 1.8
cholinesterase 1.7
pepsin 1.7
MDR 1.7
P-glycoprotein 1.6
NO synthase 1.4
demethylase 1.3
ACE 1.2
phosphodiesterase 1.2
alanine aminotransferase 1.1
protein kinase 0.8
xanthine oxidase 0.7
lipoxygenase 0.7
complex I 0.6
collagenase 0.6
acetylcholinesterase 0.6
NADPH oxidase 0.4
reverse transcriptase 0.4
aspartate aminotransferase 0.4
thrombin 0.3
NADPH oxidase 0.3
PARP 0.0
mitogen-activated protein kinase 0.0
catalase 0.0
phospholipase A2 -0.0
beta-galactosidase -0.1
superoxide dismutase -0.1
calcineurin -0.3
caspase-3 -0.4
ERK -0.5
ACS -0.5
glutathione peroxidase -0.7
lactate dehydrogenase -1.1
peroxidase -1.2
renin -1.4
luciferase -1.5
trypsin -1.6
focal adhesion kinase -1.7
alkaline phosphatase -1.8
ATPase -2.2
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Compound
4-hydroxy-3-quinolinecarboxylic acid 13.8
mCPBG 12.7
4,5,6,7-tetrahydro-1H-benzimidazole 12.4
N,N-Dimethyloctylamine 12.2
1-azabicyclo[2.2.2]oct-3-yl 12.1
Dolasetron 12.1
Granisetron 12.1
1H-indole-3-carboxylic acid 12.0
Tropisetron 11.9
C8H9NO3 11.8
Ondansetron 11.8
SB 200646 11.4
DAU 11.2
Cephaeline 11.2
DAU 11.1
Tropin 11.0
5-MeOT 10.7
3-thiophenecarboxylic acid 10.3
1-methyl-1H-indazole 10.3
Tropinone 10.2
1-(3-chlorophenyl)piperazine 10.0
Pachymic acid 10.0
UH-301 9.9
Dehydrozingerone 9.8
4-chlorobenzamide 9.4
2,2,2-trichloroethanol 9.2
Bufotenine 9.1
2-methoxybenzamide 8.9
Ketanserin 8.9
1H-indazole 8.6
imidazo[1,5-a]pyridine 8.6
1-methylpyrrolidine 8.6
pyrrolo[1,2-a]quinoxaline 8.6
AFMK 8.5
Linopirdine 8.4
(S)-AMPA 8.4
p-CA 8.4
PBG 8.4
Cisapride 8.4
Metoclopramide 8.4
1-indanol 8.3
Phenylurea 8.3
5-HT 8.3
MeODMT 8.2
Lubiprostone 8.2
BRL 8.2
Buspirone 8.2
Methysergide 8.1
1-methyl-1H-indole 8.1
Maprotiline 8.1
p-Chloroamphetamine 8.1
2-methoxybenzoic acid 8.1
Methohexital 8.0
Loperamide 7.8
Proguanil 7.8
5-HTP 7.8
Penbutolol 7.8
5-HTP 7.7
1H-pyrrolo[2,3-b]pyridine 7.7
Mirtazapine 7.7
Pargyline 7.7
3-quinolinecarboxylic acid 7.7
MK-329 7.7
Fluvoxamine 7.7
DVC 7.6
quinuclidine 7.6
quinuclidine 7.6
Veratrine 7.5
MHT 7.5
Methoxyflurane 7.5
Estracyt 7.4
Estracyt 7.4
Domperidone 7.3
benzamide 7.3
Diacetoxyscirpenol 7.2
Pindolol 7.2
4-oxobutanoic acid 7.1
1H-benzimidazole 7.1
Sumatriptan 7.1
Sodium deoxycholate 7.1
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