Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P46098 (
5-HT3 receptor
)
2,290
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
5-HT3 receptor
2290
HT3
908
5-hydroxytryptamine
433
5-HT1A
226
ICS
213
5-HT2 receptor
182
Sep
167
5-HT2A
160
5-HT receptor
155
5-HT4 receptor
124
5-HT4
117
5-HT1B
84
BRL
78
substance P
69
Mol
64
serotonin receptor
61
GABA
56
nicotinic acetylcholine receptor
54
gut
49
NK1
44
5-HT2C
41
5-HT3B
36
5-HT7
31
cholecystokinin
30
5HT1A
26
5-HT1D
26
ionotropic
24
HEK
23
muscarinic receptor
21
ornithine transcarbamylase
21
SCH
19
Gen
19
opioid receptor
19
NMDA receptor
18
olfactory
18
short form
18
5-HT6
17
prolactin
16
serotonin transporter
15
HTR3A
15
5-HT2B
14
ATP
14
GABA(A) receptor
14
tryptophan hydroxylase
14
insulin
14
adenylate cyclase
13
dopamine D2 receptor
13
CA1
12
5-HT3R
12
cage
10
calcium channel
10
beta-endorphin
10
motilin
9
cytochrome P450
9
AMP
9
CD57
9
MAO-A
9
CYP3A4
8
axonal
8
GDP
8
HTR3C
8
SERT
8
P2X
8
somatostatin
8
cyclooxygenase
8
endoplasmic reticulum
8
HTR3B
8
hole
7
GTP
7
mast cell
7
calcitonin
7
HTR3D
7
calmodulin
7
CAS
7
nitric oxide synthase
7
CA3
7
neurotransmitter receptor
7
Pol
7
fused
7
LSD
6
more...
Disease
ICS
213
cancer
212
neuroblastoma
90
irritable bowel syndrome
82
depression
78
Bezold
62
schizophrenia
35
glioma
19
SCH
19
migraine
18
Alzheimer's disease
16
alcoholism
16
motion sickness
15
anxiety disorders
15
cold
15
tumor
15
cholera
14
fibromyalgia
14
breast cancer
13
pertussis
13
Parkinson's disease
12
diabetes
12
lung cancer
11
chronic pain
10
cognitive impairment
10
major depressive disorder
10
drug abuse
10
psychosis
9
ischemic colitis
9
Frey
9
gastroparesis
9
SEM
8
pruritus
8
dyspepsia
8
alcohol abuse
8
aggression
7
DBA
7
hyperphagia
6
catalepsy
6
memory impairment
6
sexual dysfunction
6
carcinoid
6
SAR
6
addiction
6
amnesia
6
hypertension
5
GAD
5
obesity
5
hyperglycemia
5
panic disorder
5
pheochromocytoma
5
Syndrome
4
arthritis
4
disinhibition
4
panic attacks
4
multiple sclerosis
4
adenocarcinoma
4
obsessive-compulsive disorder
4
pica
4
neutropenia
4
neuropathy
4
carcinoid syndrome
4
tetanus
4
ischemia
4
colitis
4
PCA
3
rheumatoid arthritis
3
HIV
3
Steroids
3
non-small cell lung cancer
3
Evans
3
mental illness
3
Tourette syndrome
3
cocaine abuse
3
bone metastases
3
sleep disturbances
3
psychological stress
3
carcinoma
3
chronic renal failure
3
drug withdrawal
3
more...
Symptom
vomiting
394
nausea and vomiting
266
nausea
164
pain
133
diarrhea
71
constipation
68
headache
42
anesthesia
33
analgesia
31
abdominal pain
29
retching
26
discomfort
20
discomfort
20
fatigue
16
anorexia
14
seizures
11
Postoperative nausea and vomiting
10
hypothermia
10
bloating
7
tremor
7
sleepiness
7
insomnia
7
dizziness
6
Fluctuation
5
chronic constipation
4
despair
3
abdominal discomfort
3
agitation
3
hunger
3
vertigo
3
Ill
3
acute pain
3
lightheadedness
3
spasm
2
angina
2
ataxia
2
Neuropathic pain
2
bitter taste
2
Welt
2
low back pain
2
hypercapnia
2
Acute vomiting
2
pelvic pain
1
Functional abdominal pain
1
Drug-induced vomiting
1
twitching
1
tenesmus
1
flushing
1
Generalized pruritus
1
chest pain
1
Sedation
1
Chronic abdominal pain
1
bone pain
1
No adverse effect
1
blurred vision
1
Extrapyramidal symptoms
1
cough
1
rundown
1
decreased appetite
1
catarrh
1
hyperoxia
1
abnormal gait
1
disturbed balance
1
Flu-like symptoms
1
cachexia
1
incoordination
1
syncope
1
dyspnea
1
tachypnea
1
dystonia
1
heartburn
1
No vomiting
1
orofacial pain
1
intention tremor
1
Drug
Raloxifene
24
Alosetron
20
Aprepitant
17
Ethanol
17
Atropine
13
ICI
10
Ritanserin
9
Cisapride
8
CTX
8
DHT
8
DHT
8
Palonosetron hydrochloride
8
Scopolamine
8
Navoban
7
Navoban
7
Renzapride
6
Anzemet
6
Portal
6
Kytril
5
caffeine
5
Kytril
5
Anzemet
4
CaCl2
4
Tegaserod
4
Mirtazapine
4
Ramosetron hydrochloride
4
CDP
4
Histamine
4
Zofran
4
CaCl2
4
G-CSF
4
CaCl2
4
lactose
4
Domperidone
4
Cardiovasc
3
Indomethacin
3
Cilansetron
3
Tubocurarine
3
lysine
3
Zofran
3
Bemesetron
3
Tegaserod
3
Gel
3
FK 1052
2
ampicillin
2
Ginger
2
Monit
2
Rifaximin
2
Dermatol
2
Dihydro
2
PCP
2
nitroglycerin
2
Moclobemide
2
Netupitant
2
Pancopride
2
MAP
2
CPT-11
2
Indisetron hydrochloride
2
9-THC
2
IL-2
2
Menthol
2
Nephron
1
Tianeptine
1
Adriamycin
1
DEX
1
Cantor
1
Propofol
1
Serotone
1
Clonidine
1
Domin
1
Estracyt
1
Modafinil
1
CTX
1
Alanine
1
TTC
1
Ezlopitant
1
Dexfenfluramine
1
Ouabain
1
Reminyl
1
ADR
1
more...
Enzyme
tryptophan hydroxylase
15
adenylate cyclase
13
protein kinase C
12
protein kinase
10
monoamine oxidase
10
endo-N
9
CYP3A4
8
phospholipase C
7
mitogen-activated protein kinase
7
tyrosine hydroxylase
5
ERK
5
guanylate cyclase
4
alanine aminotransferase
4
catalase
4
ACS
4
superoxide dismutase
4
reverse transcriptase
3
acetylcholinesterase
3
NO synthase
3
thrombin
3
phosphodiesterase
3
ACE
3
cholinesterase
3
P-glycoprotein
3
AST
2
aldehyde dehydrogenase
2
kallikrein
2
glutamate decarboxylase
2
DMT
2
aldehyde dehydrogenase
2
DAT
2
aspartate aminotransferase
2
CaMKII
2
peroxidase
2
collagenase
2
aldehyde dehydrogenase
2
PCP
2
aldehyde dehydrogenase
2
aldehyde dehydrogenase
2
carbonyl reductase
2
pepsin
2
caspase-3
2
TACE
1
MDR
1
DOPA decarboxylase
1
FAST
1
PAL
1
MAT
1
Rex
1
complex I
1
PHD
1
xanthine oxidase
1
alkaline phosphatase
1
PAL
1
asparaginase
1
renin
1
glutathione peroxidase
1
lipoxygenase
1
focal adhesion kinase
1
ATPase
1
calcineurin
1
trypsin
1
lactate dehydrogenase
1
MAT
1
aldose reductase
1
ACAT
1
luciferase
1
NADPH oxidase
1
dihydropyrimidine dehydrogenase
1
PARP
1
demethylase
1
beta-galactosidase
1
6beta-hydroxylase
1
hydroxyprostaglandin dehydrogenase
1
phospholipase A2
1
NADPH oxidase
1
interstitial collagenase
1
dihydropyrimidine dehydrogenase
1
cholesterol acyltransferase
1
lysin
1
more...
Compound
5-HT
714
Dec
178
Ondansetron
139
Clin
103
calcium
100
ethanol
92
BRL
78
sodium
63
water
60
Granisetron
58
GABA
56
GABA
56
glutamate
43
Tropisetron
39
mCPBG
34
benzamide
34
noradrenaline
31
piperazine
29
5-hydroxytryptophan
27
Ketanserin
26
ACh
25
DAU
23
DAU
23
HCl
23
gamma-aminobutyric acid
23
nitrogen
22
NMDA
22
Neu5Ac
21
potassium
21
arginine
20
glucose
18
1H-indole-3-carboxylic acid
17
DDP
17
Metoclopramide
17
CPP
16
1-azabicyclo[2.2.2]oct-3-yl
16
cAMP
16
hydroxyindoleacetic acid
15
acetic acid
15
hydrogen
14
sulfate
14
ATP
14
oxygen
13
5-HTP
13
alanine
13
CPP
13
5-HTP
13
Atropine
13
AMPA
13
Dolasetron
12
Dopamine
12
Mg2+
11
cadmium
11
tyrosine
11
serine
11
copper
11
acetate
11
CPA
10
Buspirone
10
Risperidone
10
5-MeOT
10
hydroxide
10
phosphate
10
ICI
10
nitric oxide
10
cysteine
9
Neuronal
9
Dexamethasone
9
AMP
9
salt
9
4,5,6,7-tetrahydro-1H-benzimidazole
8
GDP
8
1H-indole
8
Substance P
8
Phe
8
COS
8
Olanzapine
8
Methysergide
8
Cisapride
8
CTX
8
more...