Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P46098 (5-HT3 receptor)
 2,290 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
5-HT3 receptor 2290
HT3 908
5-hydroxytryptamine 433
5-HT1A 226
ICS 213
5-HT2 receptor 182
Sep 167
5-HT2A 160
5-HT receptor 155
5-HT4 receptor 124
5-HT4 117
5-HT1B 84
BRL 78
substance P 69
Mol 64
serotonin receptor 61
GABA 56
nicotinic acetylcholine receptor 54
gut 49
NK1 44
5-HT2C 41
5-HT3B 36
5-HT7 31
cholecystokinin 30
5-HT1D 26
5HT1A 26
ionotropic 24
HEK 23
ornithine transcarbamylase 21
muscarinic receptor 21
opioid receptor 19
Gen 19
SCH 19
short form 18
olfactory 18
NMDA receptor 18
5-HT6 17
prolactin 16
serotonin transporter 15
HTR3A 15
insulin 14
5-HT2B 14
tryptophan hydroxylase 14
GABA(A) receptor 14
ATP 14
adenylate cyclase 13
dopamine D2 receptor 13
CA1 12
5-HT3R 12
cage 10
beta-endorphin 10
calcium channel 10
CD57 9
motilin 9
MAO-A 9
AMP 9
cytochrome P450 9
axonal 8
HTR3C 8
SERT 8
HTR3B 8
somatostatin 8
endoplasmic reticulum 8
CYP3A4 8
GDP 8
P2X 8
cyclooxygenase 8
hole 7
fused 7
Pol 7
calcitonin 7
CA3 7
GTP 7
mast cell 7
calmodulin 7
HTR3D 7
CAS 7
nitric oxide synthase 7
neurotransmitter receptor 7
CYP2D6 6
DBA 6
PBG 6
cys 6
rat) 6
glucagon 6
CB1 6
glutamate receptor 6
CCK 6
neuropeptide Y 6
TRPV1 6
SAR 6
LSD 6
5-HTTLPR 5
TPH1 5
tyrosine hydroxylase 5
serum albumin 5
acetylcholine receptor 5
5-HT1F 5
ERK 5
non-functional 5
CGRP 5
G-CSF 5
NK3 receptor 5
dopamine transporter 5
tap 5
A431 5
brain-derived neurotrophic factor 4
ACS 4
beta 1 4
albumin 4
corticotropin-releasing factor 4
L-type calcium channel 4
NMR 4
ASA 4
cytokine 4
adenylyl cyclase 4
HTR3E 4
COX-2 4
catalase 4
chloride channel 4
peptide YY 4
adrenocorticotropic hormone 4
MAO-B 4
threonine 4
superoxide dismutase 4
gastrin 4
ghrelin 4
protein kinase inhibitor 4
bradykinin 4
STZ 4
MEC 4
RIC-3 4
sodium channel 4
sigma receptor 3
guanylate cyclase 3
cannabinoid receptor 3
5-HT5A 3
parvalbumin 3
5HT1a 3
dopamine D1 receptor 3
CCK-A 3
cytochrome P-450 3
histamine H3 receptor 3
Serotonin receptor 3
IL-6 3
protein kinase C inhibitor 3
Mem 3
short isoform 3
leptin 3
ERK1 3
phosphodiesterase 3
mu opioid receptor 3
35 kDa 3
G-protein-coupled receptor 3
5-HT3E 3
MRI 3
inducible nitric oxide synthase 3
polypeptide 3
P-glycoprotein 3
REM 3
more...
Disease
ICS 213
cancer 212
neuroblastoma 90
irritable bowel syndrome 82
depression 78
Bezold 62
schizophrenia 35
glioma 19
SCH 19
migraine 18
alcoholism 16
Alzheimer's disease 16
anxiety disorders 15
cold 15
motion sickness 15
tumor 15
cholera 14
fibromyalgia 14
pertussis 13
breast cancer 13
diabetes 12
Parkinson's disease 12
lung cancer 11
major depressive disorder 10
cognitive impairment 10
drug abuse 10
chronic pain 10
psychosis 9
gastroparesis 9
ischemic colitis 9
Frey 9
pruritus 8
dyspepsia 8
SEM 8
alcohol abuse 8
aggression 7
DBA 7
memory impairment 6
catalepsy 6
sexual dysfunction 6
amnesia 6
hyperphagia 6
SAR 6
carcinoid 6
addiction 6
pheochromocytoma 5
obesity 5
hyperglycemia 5
hypertension 5
GAD 5
panic disorder 5
arthritis 4
neuropathy 4
tetanus 4
adenocarcinoma 4
disinhibition 4
obsessive-compulsive disorder 4
neutropenia 4
multiple sclerosis 4
carcinoid syndrome 4
ischemia 4
pica 4
colitis 4
panic attacks 4
Syndrome 4
metastases 3
Evans 3
thrombocytopenia 3
HIV 3
colorectal cancer 3
epilepsy 3
rheumatoid arthritis 3
cocaine abuse 3
Steroids 3
mental illness 3
Tourette syndrome 3
hypoglycemia 3
bone metastases 3
functional diarrhea 3
malabsorption 3
psychological stress 3
drug withdrawal 3
chronic renal failure 3
drug addiction 3
sleep disturbances 3
PCA 3
substance abuse 3
non-small cell lung cancer 3
carcinoma 3
osteosarcoma 2
peripheral neuropathy 2
anaphylaxis 2
Esophageal 2
PLS 2
renal failure 2
ileus 2
dementia 2
acute lymphoblastic leukemia 2
Sexual dysfunction 2
Best 2
hepatocellular carcinoma 2
epithelial ovarian cancer 2
pulmonary embolism 2
sympathomimetic 2
inflammatory bowel disease 2
lymphoma 2
GSH 2
binge eating 2
Hodgkin's disease 2
PSS 2
chronic disease 2
tardive dyskinesia 2
psychoactive substance abuse 2
dermatitis 2
sarcoma 2
long QT syndrome 2
xerostomia 2
fits 2
primary biliary cirrhosis 2
anhedonia 2
NAME 2
hallucinations 2
anemia 2
social phobia 2
stroke 2
dehydration 2
type 1 diabetes 2
CNS diseases 2
celiac disease 2
type 2 diabetes 2
enteropathy 2
SDS 2
diabetic nephropathy 2
iron deficiency 2
suicide 2
Marion 2
colon cancer 2
diabetic neuropathy 2
glucose intolerance 2
PCP 2
influenza 2
cognitive deficit 2
delusions 2
MEC 2
gastrointestinal disease 2
chronic fatigue syndrome 1
uremia 1
agranulocytosis 1
induced psychosis 1
myocardial ischemia 1
cirrhosis 1
childhood cancer 1
urethra 1
PSA 1
fatty liver 1
Opiates 1
incontinence 1
Bradley 1
brain metastases 1
audiogenic seizure 1
more...
Symptom
vomiting 394
nausea and vomiting 266
nausea 164
pain 133
diarrhea 71
constipation 68
headache 42
anesthesia 33
analgesia 31
abdominal pain 29
retching 26
discomfort 20
discomfort 20
fatigue 16
anorexia 14
seizures 11
Postoperative nausea and vomiting 10
hypothermia 10
bloating 7
tremor 7
sleepiness 7
insomnia 7
dizziness 6
Fluctuation 5
chronic constipation 4
despair 3
abdominal discomfort 3
agitation 3
hunger 3
vertigo 3
Ill 3
acute pain 3
lightheadedness 3
spasm 2
angina 2
ataxia 2
Neuropathic pain 2
bitter taste 2
Welt 2
low back pain 2
hypercapnia 2
Acute vomiting 2
pelvic pain 1
Functional abdominal pain 1
Drug-induced vomiting 1
twitching 1
tenesmus 1
flushing 1
Generalized pruritus 1
chest pain 1
Sedation 1
Chronic abdominal pain 1
bone pain 1
No adverse effect 1
blurred vision 1
Extrapyramidal symptoms 1
cough 1
rundown 1
decreased appetite 1
catarrh 1
hyperoxia 1
abnormal gait 1
disturbed balance 1
Flu-like symptoms 1
cachexia 1
incoordination 1
syncope 1
dyspnea 1
tachypnea 1
dystonia 1
heartburn 1
No vomiting 1
orofacial pain 1
intention tremor 1
Drug
Raloxifene 24
Alosetron 20
Aprepitant 17
Ethanol 17
Atropine 13
ICI 10
Ritanserin 9
Palonosetron hydrochloride 8
DHT 8
CTX 8
Scopolamine 8
Cisapride 8
DHT 8
Navoban 7
Navoban 7
Renzapride 6
Anzemet 6
Portal 6
caffeine 5
Kytril 5
Kytril 5
Anzemet 4
CaCl2 4
Tegaserod 4
Mirtazapine 4
CDP 4
CaCl2 4
Ramosetron hydrochloride 4
Zofran 4
G-CSF 4
lactose 4
CaCl2 4
Domperidone 4
Histamine 4
Cardiovasc 3
Indomethacin 3
Cilansetron 3
Tubocurarine 3
Bemesetron 3
lysine 3
Zofran 3
Tegaserod 3
Gel 3
FK 1052 2
ampicillin 2
Ginger 2
Monit 2
Rifaximin 2
Dermatol 2
Dihydro 2
PCP 2
9-THC 2
Netupitant 2
Indisetron hydrochloride 2
CPT-11 2
MAP 2
Pancopride 2
IL-2 2
Moclobemide 2
nitroglycerin 2
Menthol 2
Nephron 1
Tianeptine 1
Adriamycin 1
DEX 1
Cantor 1
Propofol 1
Serotone 1
Clonidine 1
Domin 1
Estracyt 1
Modafinil 1
CTX 1
TTC 1
Ipecac syrup 1
Itasetron 1
Dexfenfluramine 1
Ouabain 1
Alanine 1
Guanethidine 1
Ezlopitant 1
ADR 1
Ringer's solution 1
Aricept 1
Reminyl 1
K-252a 1
Estracyt 1
APD 1
Check 1
CTC 1
Quinine, 1
Loxiglumide 1
Fluphenazine 1
CTX 1
Donepezil 1
TAC 1
Asn 1
Glycyrrhiza 1
Taxol 1
Glucagon 1
Ketotifen 1
Ginseng 1
Diphenhydramine 1
Budesonide 1
Zatosetron maleate 1
Fragment 1
CTA 1
GRF 1
ROS 1
DMAA 1
Trimipramine 1
CFT 1
GHRP 1
Namenda 1
MRC 1
Tropinone 1
CTC 1
TiO2 1
Atomoxetine 1
Flesinoxan 1
Mosapride citrate 1
Rutin 1
Enzyme
tryptophan hydroxylase 15
adenylate cyclase 13
protein kinase C 12
protein kinase 10
monoamine oxidase 10
endo-N 9
CYP3A4 8
phospholipase C 7
mitogen-activated protein kinase 7
tyrosine hydroxylase 5
ERK 5
guanylate cyclase 4
alanine aminotransferase 4
catalase 4
ACS 4
superoxide dismutase 4
reverse transcriptase 3
acetylcholinesterase 3
NO synthase 3
thrombin 3
phosphodiesterase 3
ACE 3
cholinesterase 3
P-glycoprotein 3
AST 2
aldehyde dehydrogenase 2
kallikrein 2
glutamate decarboxylase 2
DMT 2
aldehyde dehydrogenase 2
DAT 2
aspartate aminotransferase 2
CaMKII 2
peroxidase 2
collagenase 2
aldehyde dehydrogenase 2
PCP 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
carbonyl reductase 2
pepsin 2
caspase-3 2
TACE 1
MDR 1
DOPA decarboxylase 1
FAST 1
PAL 1
MAT 1
Rex 1
complex I 1
PHD 1
xanthine oxidase 1
alkaline phosphatase 1
PAL 1
asparaginase 1
renin 1
glutathione peroxidase 1
lipoxygenase 1
focal adhesion kinase 1
ATPase 1
calcineurin 1
trypsin 1
lactate dehydrogenase 1
MAT 1
aldose reductase 1
ACAT 1
luciferase 1
NADPH oxidase 1
dihydropyrimidine dehydrogenase 1
PARP 1
demethylase 1
beta-galactosidase 1
6beta-hydroxylase 1
hydroxyprostaglandin dehydrogenase 1
phospholipase A2 1
NADPH oxidase 1
interstitial collagenase 1
dihydropyrimidine dehydrogenase 1
cholesterol acyltransferase 1
lysin 1
Compound
5-HT 714
Dec 178
Ondansetron 139
Clin 103
calcium 100
ethanol 92
BRL 78
sodium 63
water 60
Granisetron 58
GABA 56
GABA 56
glutamate 43
Tropisetron 39
benzamide 34
mCPBG 34
noradrenaline 31
piperazine 29
5-hydroxytryptophan 27
Ketanserin 26
ACh 25
DAU 23
gamma-aminobutyric acid 23
DAU 23
HCl 23
NMDA 22
nitrogen 22
potassium 21
Neu5Ac 21
arginine 20
glucose 18
1H-indole-3-carboxylic acid 17
DDP 17
Metoclopramide 17
CPP 16
1-azabicyclo[2.2.2]oct-3-yl 16
cAMP 16
hydroxyindoleacetic acid 15
acetic acid 15
ATP 14
sulfate 14
hydrogen 14
CPP 13
5-HTP 13
alanine 13
5-HTP 13
AMPA 13
Atropine 13
oxygen 13
Dopamine 12
Dolasetron 12
acetate 11
serine 11
Mg2+ 11
tyrosine 11
cadmium 11
copper 11
CPA 10
hydroxide 10
phosphate 10
ICI 10
nitric oxide 10
5-MeOT 10
Risperidone 10
Buspirone 10
cysteine 9
AMP 9
Dexamethasone 9
Neuronal 9
salt 9
Olanzapine 8
4,5,6,7-tetrahydro-1H-benzimidazole 8
COS 8
Substance P 8
quinoline 8
1H-indole 8
Tetrodotoxin 8
quinoline 8
CTX 8
GDP 8
DHT 8
cGMP 8
Cisapride 8
Methysergide 8
SEE 8
Phe 8
1H-benzimidazole 7
piperidine 7
1-(3-chlorophenyl)piperazine 7
1H-indazole 7
GTP 7
Cocaine 7
dipropyl 7
cobalt 7
piperidine 7
threonine 7
zinc 7
5-HIAA 6
DBA 6
Haloperidol 6
nickel 6
Morphine 6
galactose 6
Haloperidol 6
DBA 6
LSD 6
creatinine 6
His 6
PBG 6
proline 6
DBA 6
Clozapine 6
quinuclidine 5
Amphetamine 5
Loperamide 5
tryptophan 5
tryptophan 5
PGE2 5
DNA 5
urea 5
tryptophan 5
Fluvoxamine 5
Naltrexone 5
CBDCA 5
ammonium 5
benzoic acid 5
CBDCA 5
pyrazine 5
methanol 5
quinuclidine 5
Amphetamine 5
Paroxetine 5
isoquinoline 5
leucine 5
tryptophan 5
caffeine 5
Triton X-100 5
STZ 5
Tris 5
Tris 5
Diazepam 5
Imipramine 4
glutamine 4
octyl 4
octyl 4
CaCl2 4
phenol 4
silver 4
Propranolol 4
Sumatriptan 4
Glutamate 4
Gly 4
ASA 4
Nifedipine 4
HBr 4
Imipramine 4
ACS 4
methionine 4
2,2,2-trichloroethanol 4
Yohimbine 4
more...