Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P46098 (
5-HT3 receptor
)
2,290
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Pyrroloquinoxalines have proved to be a very attractive scaffold for medicinal chemist in the recent past. These compounds were extensively studied as bioactive compounds and many of them are known to be biologically and medicinally useful molecules, such as anti-HIV agents, antimalarial agents, antagonist agents, anticancer agents, and
PARP-1
inhibitors. Additionally, pyrroloquinoxalines are also important intermediates for the construction of
5-HT3 receptor
agonists. In this review the developments in biological activities and synthetic methodologies of pyrroloquinoxalines are discussed.
...
PMID:Recent progress in biological activities and synthetic methodologies of pyrroloquinoxalines. 2331 97
