Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P43146 (tumour suppressor)
 5,935 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
G protein gamma-4 subunit 12.4
leucine zipper protein 3 12.4
tumour suppressor 12.4
RING finger protein 38 12.4
PCDHGC3 12.4
protein phosphatase 2A regulatory subunit A beta isoform 12.4
ECTACC 12.4
serine/threonine kinase 38 like 12.4
GTF3C4 12.4
AMPH1 12.4
leucine-rich repeat-containing 2 12.4
KIP 2 12.4
C9orf11 12.4
PHLDB3 12.4
TPTE and PTEN homologous inositol lipid phosphatase 12.4
APITD1 12.4
Fus-2 12.4
deleted in bladder cancer 1 11.4
NITRILASE 1 11.4
NADH-ubiquinone oxidoreductase chain 4 11.4
LRRC2 11.4
FOXD4L6 11.4
progestin and adipoQ receptor family member III 11.4
ZNF454 11.4
CORO6 11.4
BR serine/threonine kinase 1 11.4
LOH2CR12 11.4
FOXD4L1 11.4
SH3GL2 protein 11.4
C9orf103 11.4
TRPM1 protein 11.4
suppression of tumorigenicity 7-like 11.4
truncated FHIT 11.4
endosulfine alpha 11.4
TMEM196 11.4
Hugl-1 11.2
LOH12CR1 10.8
ZNF479 10.8
SnuCyp-20 10.8
Kelch-like protein 6 10.8
C9orf9 10.8
LTM1 10.8
Deleted in lung and esophageal cancer 1 10.8
apoptosis repressor with CARD domain 10.8
ZNF169 10.8
ankyrin repeat domain 28 10.8
GATA zinc finger domain containing 2A 10.8
SNX32 10.8
hCAF-1 10.8
MRLC3 10.8
PTPRK protein 10.8
nin one binding protein 10.8
DBCCR1 10.6
ZZZ4 10.4
PTEN2 10.4
KIAA1797 10.4
inositol-3-phosphate synthase 1 10.4
MCMP 10.4
KLHL35 10.4
NUPL1 10.4
Ras association (RalGDS/AF-6) domain family member 1 10.4
RSL24D1 10.4
TCEB3C 10.4
E2F transcription factor 7 10.4
LIG-1 10.4
C17orf91 10.4
TMEM209 10.4
Cytoplasmic FMR1-interacting protein 2 10.4
KIAA1391 10.4
Kinesin family member 2C 10.4
NET-6 10.4
HMGIC/NFIB 10.4
opioid binding protein/cell adhesion molecule-like 10.4
High mobility group AT-hook 1 10.4
RAB36 10.4
CCDC19 10.4
DFFB 10.4
TCBA1 10.4
Migration stimulating factor 10.4
Fragile histidine triad 10.3
more...
Disease
Neurofibromatosis 1 and 2 (NF1 and NF2) 12.4
Diffuse Astrocytoma 10.4
Idiopathic ulcerative colitis 10.4
skin cancer, basal cell 10.2
Extrahepatic bile duct carcinoma 9.8
Anaplastic ependymoma 9.8
CNC2 9.4
Anaplastic Astrocytoma 9.1
lgl 8.6
HRPT2 8.5
Diffuse astrocytoma 8.5
Small cell osteosarcoma 8.4
FWT1 8.3
medullary breast carcinoma 8.3
Hamartomatous polyps 8.2
BRCAX 8.1
Cylindroma 8.0
Hairy cell leukemia variant 8.0
Multiple cancer 7.9
Ruvalcaba syndrome 7.8
CYLD 7.8
Sticker 7.7
MCC deficiency 7.7
Hippel 7.7
familial cancer 7.7
Macroprolactinomas 7.7
Typical carcinoid 7.6
EXT3 7.6
Tumor morphology 7.5
MSSE 7.5
Enteropathy-associated T-cell lymphoma 7.4
benign proliferative breast disease 7.4
FIPA 7.4
Glandular odontogenic cyst 7.4
Li-Fraumeni syndrome 7.4
Cowden syndrome 7.3
MEN1 7.3
MYH-associated polyposis 7.3
Endometrioid carcinoma 7.2
salivary gland adenoid cystic carcinoma 7.1
3p- syndrome 7.1
EXT2 7.1
NF2 7.0
pancreatic gastrinoma 7.0
Peutz-Jeghers syndrome 7.0
high-risk cancer 6.9
retinoblastoma 6.9
nevoid basal cell carcinoma syndrome 6.8
tylosis 6.8
BLL 6.7
ovarian endometrioid adenocarcinoma 6.7
XPV 6.7
GCB-DLBCL 6.7
Bone sarcomas 6.6
Anaplastic carcinoma 6.6
pseudoglioma 6.6
endocrine cancer 6.6
CM1 6.6
Odontogenic cysts 6.5
Acral lentiginous melanoma 6.5
Colorectal adenocarcinoma 6.5
Schwannomatosis 6.5
Trisomy 12 6.4
DFNA5 6.4
Oculodentodigital dysplasia 6.3
familial adenomatous polyposis 6.3
T-cell prolymphocytic leukemia 6.3
ARF 6.3
Oral Cancer 6.3
Epithelial dysplasia 6.2
Laryngopharyngeal reflux 6.2
FIH 6.2
monosomy 22 6.2
BHD 6.2
Pulmonary lymphangioleiomyomatosis 6.1
multiple endocrine neoplasia 6.1
MDM 6.1
MEN 2 6.1
breast fibroadenoma 6.0
ABC-DLBCL 6.0
more...
Symptom
prickling sensation 8.5
male subfertility 4.3
nipple discharge 3.4
nipple discharge 3.3
CSR 3.0
livedo 2.6
DNA marker 2.5
cerebellar ataxia 2.2
skin damage 1.8
cachexia 1.5
starvation 1.5
fever of unknown origin 1.4
masculinization 1.1
paraparesis 1.0
sore throat 1.0
shoulder pain 1.0
ataxia 0.8
colic 0.8
hemiplegia 0.4
pelvic pain 0.4
collapse 0.4
dystonia 0.4
exhaustion 0.2
acute stress 0.2
splenomegaly 0.1
numbness 0.1
lethargy -0.1
flushing -0.3
tinnitus -0.3
arthralgia -0.4
seizures -0.6
dizziness -0.9
insomnia -1.0
thinning -1.1
erythema -1.3
dyspnea -1.4
abdominal pain -1.5
chest pain -1.7
diarrhea -2.4
vomiting -2.6
fatigue -3.3
pain -3.3
anesthesia -3.4
headache -3.4
Drug
Dacogen 7.9
Olomoucine 6.9
Azacytidine 6.8
MDM 6.3
Podophyllum 6.0
TES 5.6
Romidepsin 5.6
Ora 5.4
PNT 5.3
Clofarabine 5.3
ROX 5.2
NLF 5.1
Tranilast 4.7
Verteporfin 4.6
Tarceva 4.6
ETS 4.5
Paraffin 4.5
Thioridazine 4.5
PFT 4.5
CDX 4.4
AGG 4.3
KCL 4.3
Triad 4.1
Triad 4.0
CDX 4.0
Vorinostat 3.9
Gleevec 3.9
Tannic acid 3.8
GEO 3.8
TEL 3.8
CTT 3.7
Vinorelbine 3.7
Ginger 3.5
KGF 3.5
Imatinib 3.4
-deoxyadenosine 3.4
Orphan 3.3
IL-11 3.3
Salicylate 3.3
CED 3.2
Parkin 3.1
Parkin 3.1
R1881 3.1
Everolimus 3.0
OTC 2.9
MDS 2.9
G418 2.8
Erlotinib 2.8
Riboflavin 2.8
Irinotecan 2.7
Activin 2.7
Cetuximab 2.5
GRF 2.5
lysine 2.4
ADM 2.4
CTC 2.3
OTC 2.3
ACT 2.3
DHT 2.3
DMAP 2.2
Retinoic acid 2.2
MRC 2.2
Herceptin 2.2
DHT 2.2
RFP 2.1
CoCl2 2.1
CoCl2 2.1
CTC 2.1
Lovastatin 2.0
IL-1ra 2.0
Alanine 1.9
CTA 1.9
CAM 1.9
Mutagen 1.9
BH4 1.8
Ranitidine 1.8
Taxol 1.7
9-THC 1.6
Gelatin 1.6
PTC 1.6
more...
Enzyme
adenylylsulfate-ammonia adenylyltransferase 12.4
EC 3.6.2.1 11.4
ChEH 10.8
STK11 8.0
STK4 8.0
nitric oxide dioxygenase 7.3
Ap4A hydrolase 6.8
methylthioadenosine phosphorylase 6.5
poly(A)-specific ribonuclease 6.5
10-formyltetrahydrofolate dehydrogenase 6.3
ADE2 6.1
protein L-isoaspartyl methyltransferase 6.1
poly(A)-specific ribonuclease 6.0
gluconokinase 5.9
pyruvate dehydrogenase phosphatase 5.9
EC 2.6.1.16 5.9
fumarase 5.7
methylenetetrahydrofolate dehydrogenase 5.6
caspase-2 5.4
caspase-2 5.3
guanidinoacetate methyltransferase 5.3
methylenetetrahydrofolate dehydrogenase 5.2
DNA methyltransferase 5.2
jararhagin 5.1
alpha-N-acetylgalactosaminidase 5.1
oxoglutarate dehydrogenase 5.1
inositol phosphatase 5.0
Omi/HtrA2 5.0
PHD 5.0
phosphoinositide 3-kinase 5.0
APC 4.9
cdc2 4.9
lysine acetyltransferase 4.9
guanylate kinase 4.9
phosphatidylserine decarboxylase 4.8
methionine synthase reductase 4.7
endonuclease VII 4.7
AMP-activated kinase 4.5
histone demethylase 4.5
histone acetyltransferase 4.4
PTPase 4.4
AGT 4.4
AMP-activated protein kinase 4.4
ubiquitin-protein ligase 4.3
AMPK 4.3
biliverdin reductase 4.3
fumarylacetoacetate hydrolase 4.2
p100 4.2
TSA 4.2
protein phosphatase 2A 4.1
prolyl hydroxylase 4.1
phosphoglycerate dehydrogenase 4.1
NAT 4.0
TOR 3.9
proteasome 3.9
nicotinamide phosphoribosyltransferase 3.9
PDK1 3.8
CEP 3.8
triphosphatase 3.8
polo-like kinase 1 3.8
nitrilase 3.8
methionine synthase 3.7
BAT 3.7
aminopeptidase A 3.7
TSP-1 3.7
CGT 3.6
NPL 3.6
methionine synthase 3.6
PARP 3.5
protein kinase 3.4
N-acetylglucosaminyltransferase 3.4
AMPK 3.4
luciferase 3.3
ERK 3.3
calcineurin 3.3
DNA ligase 3.3
DNA ligase 3.3
CEP 3.3
GRK5 3.3
phosphatidylinositol 3-kinase 3.2
more...
Compound
N-Hydroxy-2-acetylaminofluorene 8.4
Tuberin 7.8
5-Aza-2'-deoxycytidine 7.3
Pheophorbide a 7.1
Pheophorbide a 7.1
DCC 7.0
Microcephalin 6.9
Thiostrepton 6.5
Nitrosamine 6.5
Fusaric acid 6.3
Fusaric acid 6.3
Fusaric acid 6.3
BIF 6.1
TES 6.0
Azoxymethane 6.0
UPP 5.8
Bisulfite 5.8
suberic acid 5.6
NIX 5.6
Piperlongumine 5.6
NOXA 5.4
Gambogic acid 5.3
DLG 5.3
PNT 5.3
Lomefloxacin 5.2
FAP 5.2
FAP 5.2
Xanthohumol 5.1
alpha-Naphthoflavone 5.1
alpha-Naphthoflavone 5.1
alpha-Naphthoflavone 5.0
Temsirolimus 5.0
AICAR 5.0
Sodium bisulfite 5.0
Estrone 4.9
Asbestos 4.9
BTG 4.9
Withaferin A 4.9
5,10-methenyltetrahydrofolate 4.9
BTG 4.9
MNT 4.9
DAC 4.8
GAP 4.8
DEK 4.8
CMK 4.8
Parthenolide 4.7
MGA 4.7
DBD 4.7
Aristolochic acid 4.7
Arecoline 4.7
Mithramycin 4.7
F23 4.6
Calyculin A 4.6
DFS 4.6
Parthenolide 4.5
BAF 4.5
Rottlerin 4.5
Pentamidine 4.4
Geldanamycin 4.4
Rottlerin 4.4
Rottlerin 4.4
PALA 4.4
S 1 4.3
Tetrahydrocannabinol 4.3
Carcinogen 4.2
Cypermethrin 4.2
Letrozole 4.2
AICAR 4.2
Isoform 4.2
TEP 4.2
tetraphosphate 4.1
IDP 4.1
Hesperidin 4.1
TSC 4.1
TET 4.0
TET 4.0
Ubiquitin 4.0
aflatoxin B1 4.0
Histone 4.0
Quinolinic acid 3.9
more...