Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P43146 (tumour suppressor)
 5,935 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AMPH1 12.4
PHLDB3 12.4
tumour suppressor 12.4
serine/threonine kinase 38 like 12.4
leucine zipper protein 3 12.4
PCDHGC3 12.4
TPTE and PTEN homologous inositol lipid phosphatase 12.4
G protein gamma-4 subunit 12.4
RING finger protein 38 12.4
APITD1 12.4
ECTACC 12.4
protein phosphatase 2A regulatory subunit A beta isoform 12.4
KIP 2 12.4
GTF3C4 12.4
leucine-rich repeat-containing 2 12.4
C9orf11 12.4
Fus-2 12.4
NITRILASE 1 11.4
BR serine/threonine kinase 1 11.4
TMEM196 11.4
LRRC2 11.4
progestin and adipoQ receptor family member III 11.4
LOH2CR12 11.4
ZNF454 11.4
TRPM1 protein 11.4
suppression of tumorigenicity 7-like 11.4
CORO6 11.4
deleted in bladder cancer 1 11.4
FOXD4L6 11.4
truncated FHIT 11.4
FOXD4L1 11.4
endosulfine alpha 11.4
C9orf103 11.4
NADH-ubiquinone oxidoreductase chain 4 11.4
SH3GL2 protein 11.4
Hugl-1 11.2
Kelch-like protein 6 10.8
SNX32 10.8
apoptosis repressor with CARD domain 10.8
MRLC3 10.8
more...
Disease
Neurofibromatosis 1 and 2 (NF1 and NF2) 12.4
Idiopathic ulcerative colitis 10.4
Diffuse Astrocytoma 10.4
skin cancer, basal cell 10.2
Anaplastic ependymoma 9.8
Extrahepatic bile duct carcinoma 9.8
CNC2 9.4
Anaplastic Astrocytoma 9.1
lgl 8.6
HRPT2 8.5
Diffuse astrocytoma 8.5
Small cell osteosarcoma 8.4
FWT1 8.3
medullary breast carcinoma 8.3
Hamartomatous polyps 8.2
BRCAX 8.1
Cylindroma 8.0
Hairy cell leukemia variant 8.0
Multiple cancer 7.9
Ruvalcaba syndrome 7.8
CYLD 7.8
Sticker 7.7
MCC deficiency 7.7
Hippel 7.7
familial cancer 7.7
Macroprolactinomas 7.7
Typical carcinoid 7.6
EXT3 7.6
Tumor morphology 7.5
MSSE 7.5
Enteropathy-associated T-cell lymphoma 7.4
benign proliferative breast disease 7.4
Glandular odontogenic cyst 7.4
FIPA 7.4
Li-Fraumeni syndrome 7.4
Cowden syndrome 7.3
MEN1 7.3
MYH-associated polyposis 7.3
Endometrioid carcinoma 7.2
salivary gland adenoid cystic carcinoma 7.1
more...
Symptom
prickling sensation 8.5
male subfertility 4.3
nipple discharge 3.4
nipple discharge 3.3
CSR 3.0
livedo 2.6
DNA marker 2.5
cerebellar ataxia 2.2
skin damage 1.8
cachexia 1.5
starvation 1.5
fever of unknown origin 1.4
masculinization 1.1
paraparesis 1.0
sore throat 1.0
shoulder pain 1.0
ataxia 0.8
colic 0.8
hemiplegia 0.4
pelvic pain 0.4
collapse 0.4
dystonia 0.4
exhaustion 0.2
acute stress 0.2
splenomegaly 0.1
numbness 0.1
lethargy -0.1
flushing -0.3
tinnitus -0.3
arthralgia -0.4
seizures -0.6
dizziness -0.9
insomnia -1.0
thinning -1.1
erythema -1.3
dyspnea -1.4
abdominal pain -1.5
chest pain -1.7
diarrhea -2.4
vomiting -2.6
more...
Drug
Dacogen 7.9
Olomoucine 6.9
Azacytidine 6.8
MDM 6.3
Podophyllum 6.0
TES 5.6
Romidepsin 5.6
Ora 5.4
PNT 5.3
Clofarabine 5.3
ROX 5.2
NLF 5.1
Tranilast 4.7
Verteporfin 4.6
Tarceva 4.6
ETS 4.5
Paraffin 4.5
Thioridazine 4.5
PFT 4.5
CDX 4.4
AGG 4.3
KCL 4.3
Triad 4.1
Triad 4.0
CDX 4.0
Vorinostat 3.9
Gleevec 3.9
Tannic acid 3.8
GEO 3.8
TEL 3.8
CTT 3.7
Vinorelbine 3.7
Ginger 3.5
KGF 3.5
Imatinib 3.4
-deoxyadenosine 3.4
Orphan 3.3
IL-11 3.3
Salicylate 3.3
CED 3.2
more...
Enzyme
adenylylsulfate-ammonia adenylyltransferase 12.4
EC 3.6.2.1 11.4
ChEH 10.8
STK11 8.0
STK4 8.0
nitric oxide dioxygenase 7.3
Ap4A hydrolase 6.8
methylthioadenosine phosphorylase 6.5
poly(A)-specific ribonuclease 6.5
10-formyltetrahydrofolate dehydrogenase 6.3
ADE2 6.1
protein L-isoaspartyl methyltransferase 6.1
poly(A)-specific ribonuclease 6.0
gluconokinase 5.9
pyruvate dehydrogenase phosphatase 5.9
EC 2.6.1.16 5.9
fumarase 5.7
methylenetetrahydrofolate dehydrogenase 5.6
caspase-2 5.4
caspase-2 5.3
guanidinoacetate methyltransferase 5.3
methylenetetrahydrofolate dehydrogenase 5.2
DNA methyltransferase 5.2
jararhagin 5.1
oxoglutarate dehydrogenase 5.1
alpha-N-acetylgalactosaminidase 5.1
inositol phosphatase 5.0
Omi/HtrA2 5.0
PHD 5.0
phosphoinositide 3-kinase 5.0
APC 4.9
cdc2 4.9
lysine acetyltransferase 4.9
guanylate kinase 4.9
phosphatidylserine decarboxylase 4.8
methionine synthase reductase 4.7
endonuclease VII 4.7
AMP-activated kinase 4.5
histone demethylase 4.5
histone acetyltransferase 4.4
more...
Compound
N-Hydroxy-2-acetylaminofluorene 8.4
Tuberin 7.8
5-Aza-2'-deoxycytidine 7.3
Pheophorbide a 7.1
Pheophorbide a 7.1
DCC 7.0
Microcephalin 6.9
Thiostrepton 6.5
Nitrosamine 6.5
Fusaric acid 6.3
Fusaric acid 6.3
Fusaric acid 6.3
BIF 6.1
TES 6.0
Azoxymethane 6.0
UPP 5.8
Bisulfite 5.8
suberic acid 5.6
NIX 5.6
Piperlongumine 5.6
NOXA 5.4
Gambogic acid 5.3
DLG 5.3
PNT 5.3
FAP 5.2
FAP 5.2
Lomefloxacin 5.2
Xanthohumol 5.1
alpha-Naphthoflavone 5.1
alpha-Naphthoflavone 5.1
alpha-Naphthoflavone 5.0
Temsirolimus 5.0
AICAR 5.0
Sodium bisulfite 5.0
Estrone 4.9
Asbestos 4.9
Withaferin A 4.9
BTG 4.9
5,10-methenyltetrahydrofolate 4.9
BTG 4.9
more...