Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P43146 (tumour suppressor)
5,935 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein tumour suppressor 5935 p53 2001 Mol 462 Sep 378 PTEN 233 p16 206 p21 184 phosphatase 141 BRCA1 141 histone 127 ubiquitin 120 MDM2 118 INK4a 115 E-cadherin 113 mutant p53 101 p16INK4a 99 catenin 93 APC 91 adenomatous polyposis coli 87 BRCA2 87 ARF 85 CDKN2A 85 AKT 84 ras 82 cyclin 81 PI3K 80 p73 79 beta-catenin 79 proteasome 78 mTOR 76 cyclin D1 72 Bcl-2 72 pRb 71 proto-oncogene 70 ATM 68 LKB1 68 E3 ubiquitin ligase 67 Mdm2 65 tensin 65 telomeric 62 more...

Disease cancer 2634 tumorigenesis 493 carcinogenesis 478 breast cancer 476 carcinoma 344 tumor 308 colorectal cancer 288 retinoblastoma 247 melanoma 201 leukemia 200 lung cancer 178 Hippel 175 metastases 145 prostate cancer 137 squamous cell carcinoma 133 hepatocellular carcinoma 131 ovarian cancer 115 adenocarcinoma 113 renal cell carcinoma 108 gastric cancer 94 APC 93 tumor progression 92 colon cancer 90 ARF 85 ATM 83 lymphoma 79 adenoma 79 glioma 70 WT1 69 neuroblastoma 68 familial adenomatous polyposis 66 acute myeloid leukemia 64 dysplasia 64 glioblastoma 62 NF2 62 multiple endocrine neoplasia 60 pancreatic cancer 60 cervical cancer 57 non-small cell lung cancer 54 MCF 47 more...

Symptom starvation 13 seizures 10 collapse 7 ataxia 5 pain 5 cerebellar ataxia 3 exhaustion 3 cachexia 3 splenomegaly 2 abdominal pain 2 diarrhea 2 anesthesia 2 dyspnea 2 dystonia 2 nipple discharge 1 paraparesis 1 male subfertility 1 lethargy 1 headache 1 dizziness 1 erythema 1 colic 1 acute stress 1 vomiting 1 chest pain 1 DNA marker 1 nipple discharge 1 hemiplegia 1 tinnitus 1 skin damage 1 arthralgia 1 thinning 1 CSR 1 numbness 1 livedo 1 fever of unknown origin 1 sore throat 1 insomnia 1 shoulder pain 1 flushing 1 more...

Drug lysine 56 Dermatol 36 ETS 11 Paraffin 9 ROS 9 MAP 7 MDM 6 NADH 6 CSF 5 Imatinib 5 TES 5 Asn 5 IFN-gamma 4 GEO 4 DNase I 4 -deoxyadenosine 4 ABC 4 CAM 4 Mutagen 4 ascorbate 4 Gleevec 4 IL-2 4 Parkin 3 ENT 3 AGG 3 ADM 3 MRC 3 Parkin 3 caffeine 3 Retinoic acid 3 G418 3 MDS 3 Triad 2 IL-11 2 Podophyllum 2 Alanine 2 ROC 2 ACT 2 Spectrum 2 niacin 2 more...

Enzyme ERK 179 protein kinase 162 mitogen-activated protein kinase 118 APC 94 proteasome 78 luciferase 72 focal adhesion kinase 63 AMP-activated protein kinase 50 cdc2 47 phosphoinositide 3-kinase 34 DNA methyltransferase 33 calcineurin 32 RNA polymerase 30 caspase-3 29 PARP 29 protein kinase C 29 MEK 24 AMPK 24 reverse transcriptase 24 STK11 23 AMPK 23 phosphatidylinositol 3-kinase 19 glutathione S-transferase 18 ATPase 18 succinate dehydrogenase 13 histone acetyltransferase 11 fumarase 11 superoxide dismutase 10 caspase-8 10 protein phosphatase 2A 10 catalase 10 GSK 10 DNA polymerase 9 topoisomerase 9 NQO1 8 topoisomerase 8 MAP 7 glutathione peroxidase 7 IKK 7 endonuclease 7 more...

Compound DNA 1512 Dec 435 Clin 161 oxygen 132 urea 91 serine 85 tyrosine 74 lysine 65 threonine 63 arginine 63 DCC 55 ATP 43 glucose 39 MDA 38 calcium 37 zinc 34 phosphate 33 cysteine 32 alanine 30 His 28 AMP 28 leucine 24 proline 24 TNM 22 MTT 22 methionine 21 water 20 NAD 20 iron 18 5-Aza-2'-deoxycytidine 17 hydrogen 17 MEK 16 pyrene 16 NAD 16 retinoic acid 15 cAMP 14 aflatoxin B1 14 Histone 14 nitric oxide 14 GTP 13 more...

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