Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P43146 (tumour suppressor)
 5,935 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tumour suppressor 5935
p53 2001
Mol 462
Sep 378
PTEN 233
p16 206
p21 184
phosphatase 141
BRCA1 141
histone 127
ubiquitin 120
MDM2 118
INK4a 115
E-cadherin 113
mutant p53 101
p16INK4a 99
catenin 93
APC 91
adenomatous polyposis coli 87
BRCA2 87
more...
Disease
cancer 2634
tumorigenesis 493
carcinogenesis 478
breast cancer 476
carcinoma 344
tumor 308
colorectal cancer 288
retinoblastoma 247
melanoma 201
leukemia 200
lung cancer 178
Hippel 175
metastases 145
prostate cancer 137
squamous cell carcinoma 133
hepatocellular carcinoma 131
ovarian cancer 115
adenocarcinoma 113
renal cell carcinoma 108
gastric cancer 94
more...
Symptom
starvation 13
seizures 10
collapse 7
pain 5
ataxia 5
cerebellar ataxia 3
cachexia 3
exhaustion 3
abdominal pain 2
diarrhea 2
dystonia 2
anesthesia 2
dyspnea 2
splenomegaly 2
hemiplegia 1
paraparesis 1
fever of unknown origin 1
headache 1
dizziness 1
vomiting 1
more...
Drug
lysine 56
Dermatol 36
ETS 11
Paraffin 9
ROS 9
MAP 7
MDM 6
NADH 6
CSF 5
Imatinib 5
Asn 5
TES 5
IFN-gamma 4
-deoxyadenosine 4
GEO 4
ascorbate 4
CAM 4
ABC 4
Gleevec 4
DNase I 4
more...
Enzyme
ERK 179
protein kinase 162
mitogen-activated protein kinase 118
APC 94
proteasome 78
luciferase 72
focal adhesion kinase 63
AMP-activated protein kinase 50
cdc2 47
phosphoinositide 3-kinase 34
DNA methyltransferase 33
calcineurin 32
RNA polymerase 30
PARP 29
caspase-3 29
protein kinase C 29
MEK 24
reverse transcriptase 24
AMPK 24
AMPK 23
more...
Compound
DNA 1512
Dec 435
Clin 161
oxygen 132
urea 91
serine 85
tyrosine 74
lysine 65
arginine 63
threonine 63
DCC 55
ATP 43
glucose 39
MDA 38
calcium 37
zinc 34
phosphate 33
cysteine 32
alanine 30
AMP 28
more...