Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P43026 (
lipopolysaccharide
)
62,215
document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
lipopolysaccharide
62215
cytokine
8488
tumor necrosis factor
8035
IL-6
5465
TNF
5231
LPS
4418
Sep
4098
TLR4
3859
inducible nitric oxide synthase
3838
Mol
3800
interleukin-6
2456
IL-10
2363
interferon
2188
nitric oxide synthase
2180
TNF-alpha
2100
interferon-gamma
2082
tumor necrosis factor alpha
1992
p38
1914
IL-8
1767
p65
1730
IL-1
1700
cyclooxygenase-2
1642
CD14
1510
NMR
1450
Pseudomonas
1450
THP
1136
COX-2
1105
IFN
1099
chemokine
1088
gut
1084
IL-1 beta
1081
IFN-gamma
1066
IL-4
1027
cyclooxygenase
932
MAPK
914
myeloperoxidase
867
TLR2
834
Cytokine
827
JNK
803
galactosamine
753
superoxide dismutase
712
insulin
699
caspase-3
686
mitogen-activated protein
661
CD4
651
ERK
639
ERK1
632
membrane protein
628
lymphoid
623
collagen
608
IL-2
607
IgA
593
ATP
586
thymus
574
MyD88
566
heme oxygenase-1
546
interleukin-10
541
CD86
525
extracellular signal-regulated kinase
516
c-Jun
510
interleukin 6
492
CD40
491
interferon gamma
479
MCP-1
473
CD11b
466
granulocyte
460
p38 mitogen-activated protein kinase
457
macrophage colony-stimulating factor
443
albumin
428
AP-1
420
catalase
416
polypeptide
415
glycoprotein
412
SDS
410
IL-1 alpha
406
GSH
402
CD80
391
Tumor necrosis factor
390
tissue factor
388
granulocyte-macrophage colony-stimulating factor
382
more...
Disease
sepsis
3117
sepsis
3012
cancer
1765
tumor
1743
bacterial infection
743
depression
682
atherosclerosis
657
Alzheimer's disease
629
infectious diseases
589
arthritis
581
plaque
580
obesity
528
rheumatoid arthritis
519
diabetes
514
periodontitis
492
Parkinson's disease
480
endotoxic shock
478
Klebsiella
467
cholera
462
BDC
459
asthma
439
ischemia
427
SDS
411
GSH
402
colitis
395
Yersinia
379
HIV
377
Infection
334
pneumonia
331
Haemophilus
325
immunodeficiency
321
Mycobacterium
314
leukemia
312
NAME
306
Brucella abortus
288
pertussis
288
cystic fibrosis
282
MIP
280
pulmonary edema
278
stroke
270
inflammatory bowel disease
270
periodontal disease
262
chronic obstructive pulmonary disease
248
Chlamydia
246
virus infection
241
mastitis
232
multiple sclerosis
228
hepatitis
227
hepatocellular carcinoma
224
Proteus
217
tuberculosis
213
melanoma
212
Shigella flexneri
209
Bordetella
207
hypertension
198
systemic lupus erythematosus
197
Shigella
197
Spleen
193
peritonitis
189
liver disease
189
tumor growth
187
influenza
185
carcinogenesis
185
cold
182
NOD
178
lymphoma
178
brucellosis
178
cardiovascular disease
176
DBA
170
type 2 diabetes
168
autoimmune disease
163
adult respiratory distress syndrome
163
carcinoma
160
uterus
159
cognitive impairment
159
AIDS
158
Blocking
157
disseminated intravascular coagulation
156
bacteremia
155
osteoarthritis
152
more...
Symptom
pain
457
respiratory distress
322
diarrhea
272
hypothermia
210
anorexia
183
anesthesia
130
seizures
81
collapse
80
starvation
71
splenomegaly
65
cachexia
61
hyperoxia
56
fatigue
50
acute stress
47
vomiting
40
lethargy
39
cough
37
functional recovery
36
analgesia
33
headache
32
exhaustion
31
nausea
24
acidity
22
tremor
20
abdominal pain
20
weakness
19
Ill
19
overweight
18
arthralgia
18
despair
17
tachypnea
17
erythema
16
HSA
15
memory loss
15
insomnia
13
sleepiness
13
twitching
13
discomfort
12
agitation
12
discomfort
12
pelvic pain
12
ataxia
11
thinning
11
hypercapnia
11
adipsia
10
chills
10
low back pain
9
dyspnea
9
flushing
9
angina
9
myalgia
8
sore throat
8
Neuropathic pain
8
colic
8
microbial colonization
8
acute pain
8
hepatomegaly
7
POA
7
spasm
7
polyuria
6
dry eye
6
hepatosplenomegaly
6
wheezing
6
bladder pain
6
urinary frequency
6
paresis
6
back pain
5
oliguria
5
bradykinesia
5
constipation
5
muscle cramps
4
dental pain
4
intestinal bleeding
4
nasal congestion
4
incoordination
4
ophthalmoplegia
4
nausea and vomiting
4
hemoptysis
3
prostration
3
neuralgia
3
more...
Drug
IFN-gamma
1023
IL-2
609
CSF
453
lysine
348
ROS
317
Indomethacin
156
MAP
139
Gel
137
Dermatol
128
IFN-beta
109
Cardiovasc
98
Nitric Oxide
97
vitamin E
95
ascorbate
87
Heme
79
IL-1ra
78
p75
77
TAK
76
Leaf
76
G-CSF
69
lactose
67
Bifidobacterium
66
Monit
65
Ethanol
64
NADH
60
MOF
57
ampicillin
55
Nephron
52
NAG
51
Histamine
50
Asthma
49
CCL
49
ICI
49
Glutathione
47
caffeine
45
Glycyrrhiza
41
CTX
40
MIL
39
Taxol
38
ABC
38
Asn
37
DNase I
36
Aminoguanidine
35
DEX
34
BH4
33
Colistin
32
Forskolin
30
Dial
30
Propofol
29
Meth
28
Activin
28
Fraction
27
Albumin
25
Nephron
25
Angiotensin II
24
ETA
23
CaCl2
23
CaCl2
23
CaCl2
23
EE2
23
CAM
23
Portal
22
Simvastatin
21
CTX
21
BTC
21
ALA
21
EPA
21
citric acid
21
CTX
21
FAD
20
IL-11
20
Emodin
20
Emodin
20
Methylene blue
20
Retinoic acid
19
Fluorescein
19
TiO2
19
balanced salt solution
19
Rolipram
18
Lovastatin
18
more...
Enzyme
mitogen-activated protein kinase
3245
NO synthase
1523
peroxidase
1050
superoxide dismutase
844
protein kinase
802
ERK
802
luciferase
627
protein kinase C
617
alanine aminotransferase
616
caspase-3
524
catalase
472
aspartate aminotransferase
461
NOS
428
caspase-1
410
lysozyme
366
IKK
348
lactate dehydrogenase
348
thrombin
321
NADPH oxidase
315
reverse transcriptase
310
NADPH oxidase
305
alkaline phosphatase
287
MIP
280
focal adhesion kinase
279
trypsin
251
phospholipase A2
245
collagenase
233
glutathione peroxidase
229
MEK
223
phosphodiesterase
219
heme oxygenase
201
AMP-activated protein kinase
183
phosphatidylinositol 3-kinase
181
proteasome
181
elastase
168
ACS
157
phospholipase C
157
ATPase
153
arginase
152
RNA polymerase
137
guanylate cyclase
131
tyrosine hydroxylase
131
proteinase K
127
lipoxygenase
124
xanthine oxidase
122
RNase
121
APC
118
RNase
117
AST
113
thromboplastin
107
MAP
104
AMPK
103
acid phosphatase
101
neutrophil elastase
99
PARP
99
adenylate cyclase
96
caspase-11
89
acetylcholinesterase
89
phosphoinositide 3-kinase
88
caspase-11
88
caspase-8
85
transcriptase
85
calcineurin
84
renin
81
AMPK
80
GSK
78
lipase
74
urokinase-type plasminogen activator
74
glutathione S-transferase
73
neuraminidase
66
NQO1
65
tissue plasminogen activator
62
plasmin
61
matrix metalloproteinase 9
58
cathepsin K
57
MMP-3
57
creatine kinase
57
indoleamine 2,3-dioxygenase
56
histidine decarboxylase
55
caspase-9
55
more...
Compound
nitric oxide
6920
TNF
5231
Dec
4391
DNA
3124
oxygen
2787
Clin
2190
water
1828
sodium
1627
acetate
1619
arginine
1511
glucose
1475
calcium
1403
phosphate
1185
galactose
1167
THP
1139
THP
1137
sulfate
1042
ethanol
804
PGE
794
nitrogen
685
iron
660
hydrogen
595
PGE2
590
ATP
590
tyrosine
557
cAMP
512
cysteine
511
phenol
506
lysine
487
SDS
474
nitrate
442
GSH
427
GSH
427
Phe
415
leucine
413
heptose
412
heptose
412
heptose
412
MTT
382
serine
366
urea
351
zinc
315
methanol
303
alanine
294
H2O2
293
salt
282
methionine
273
glutamate
268
AMP
263
acetic acid
260
silver
251
cGMP
248
GlcNAc
242
thioglycollate
241
creatinine
238
PMA
232
CO2
220
tryptophan
220
NH2
214
PMA
210
Dexamethasone
208
tryptophan
207
bromide
205
tryptophan
202
tryptophan
202
hexose
202
potassium
199
EDTA
198
EDTA
196
N-acetylcysteine
188
ADP
183
ethyl acetate
182
prostacyclin
179
DBA
178
copper
177
ACTH
176
DBA
169
DBA
168
ADP
167
ADP
164
more...