Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P43026 (lipopolysaccharide)
62,215 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lipopolysaccharide 62215
cytokine 8488
tumor necrosis factor 8035
IL-6 5465
TNF 5231
LPS 4418
Sep 4098
TLR4 3859
inducible nitric oxide synthase 3838
Mol 3800
interleukin-6 2456
IL-10 2363
interferon 2188
nitric oxide synthase 2180
TNF-alpha 2100
interferon-gamma 2082
tumor necrosis factor alpha 1992
p38 1914
IL-8 1767
p65 1730
IL-1 1700
cyclooxygenase-2 1642
CD14 1510
NMR 1450
Pseudomonas 1450
THP 1136
COX-2 1105
IFN 1099
chemokine 1088
gut 1084
IL-1 beta 1081
IFN-gamma 1066
IL-4 1027
cyclooxygenase 932
MAPK 914
myeloperoxidase 867
TLR2 834
Cytokine 827
JNK 803
galactosamine 753
superoxide dismutase 712
insulin 699
caspase-3 686
mitogen-activated protein 661
CD4 651
ERK 639
ERK1 632
membrane protein 628
lymphoid 623
collagen 608
IL-2 607
IgA 593
ATP 586
thymus 574
MyD88 566
heme oxygenase-1 546
interleukin-10 541
CD86 525
extracellular signal-regulated kinase 516
c-Jun 510
interleukin 6 492
CD40 491
interferon gamma 479
MCP-1 473
CD11b 466
granulocyte 460
p38 mitogen-activated protein kinase 457
macrophage colony-stimulating factor 443
albumin 428
AP-1 420
catalase 416
polypeptide 415
glycoprotein 412
SDS 410
IL-1 alpha 406
GSH 402
CD80 391
Tumor necrosis factor 390
tissue factor 388
granulocyte-macrophage colony-stimulating factor 382
more...
Disease
sepsis 3117
sepsis 3012
cancer 1765
tumor 1743
bacterial infection 743
depression 682
atherosclerosis 657
Alzheimer's disease 629
infectious diseases 589
arthritis 581
plaque 580
obesity 528
rheumatoid arthritis 519
diabetes 514
periodontitis 492
Parkinson's disease 480
endotoxic shock 478
Klebsiella 467
cholera 462
BDC 459
asthma 439
ischemia 427
SDS 411
GSH 402
colitis 395
Yersinia 379
HIV 377
Infection 334
pneumonia 331
Haemophilus 325
immunodeficiency 321
Mycobacterium 314
leukemia 312
NAME 306
Brucella abortus 288
pertussis 288
cystic fibrosis 282
MIP 280
pulmonary edema 278
stroke 270
inflammatory bowel disease 270
periodontal disease 262
chronic obstructive pulmonary disease 248
Chlamydia 246
virus infection 241
mastitis 232
multiple sclerosis 228
hepatitis 227
hepatocellular carcinoma 224
Proteus 217
tuberculosis 213
melanoma 212
Shigella flexneri 209
Bordetella 207
hypertension 198
systemic lupus erythematosus 197
Shigella 197
Spleen 193
peritonitis 189
liver disease 189
tumor growth 187
influenza 185
carcinogenesis 185
cold 182
NOD 178
lymphoma 178
brucellosis 178
cardiovascular disease 176
DBA 170
type 2 diabetes 168
autoimmune disease 163
adult respiratory distress syndrome 163
carcinoma 160
uterus 159
cognitive impairment 159
AIDS 158
Blocking 157
disseminated intravascular coagulation 156
bacteremia 155
osteoarthritis 152
more...
Symptom
pain 457
respiratory distress 322
diarrhea 272
hypothermia 210
anorexia 183
anesthesia 130
seizures 81
collapse 80
starvation 71
splenomegaly 65
cachexia 61
hyperoxia 56
fatigue 50
acute stress 47
vomiting 40
lethargy 39
cough 37
functional recovery 36
analgesia 33
headache 32
exhaustion 31
nausea 24
acidity 22
tremor 20
abdominal pain 20
weakness 19
Ill 19
overweight 18
arthralgia 18
despair 17
tachypnea 17
erythema 16
HSA 15
memory loss 15
insomnia 13
sleepiness 13
twitching 13
discomfort 12
agitation 12
discomfort 12
pelvic pain 12
ataxia 11
thinning 11
hypercapnia 11
adipsia 10
chills 10
low back pain 9
dyspnea 9
flushing 9
angina 9
myalgia 8
sore throat 8
Neuropathic pain 8
colic 8
microbial colonization 8
acute pain 8
hepatomegaly 7
POA 7
spasm 7
polyuria 6
dry eye 6
hepatosplenomegaly 6
wheezing 6
bladder pain 6
urinary frequency 6
paresis 6
back pain 5
oliguria 5
bradykinesia 5
constipation 5
muscle cramps 4
dental pain 4
intestinal bleeding 4
nasal congestion 4
incoordination 4
ophthalmoplegia 4
nausea and vomiting 4
hemoptysis 3
prostration 3
neuralgia 3
more...
Drug
IFN-gamma 1023
IL-2 609
CSF 453
lysine 348
ROS 317
Indomethacin 156
MAP 139
Gel 137
Dermatol 128
IFN-beta 109
Cardiovasc 98
Nitric Oxide 97
vitamin E 95
ascorbate 87
Heme 79
IL-1ra 78
p75 77
TAK 76
Leaf 76
G-CSF 69
lactose 67
Bifidobacterium 66
Monit 65
Ethanol 64
NADH 60
MOF 57
ampicillin 55
Nephron 52
NAG 51
Histamine 50
Asthma 49
CCL 49
ICI 49
Glutathione 47
caffeine 45
Glycyrrhiza 41
CTX 40
MIL 39
Taxol 38
ABC 38
Asn 37
DNase I 36
Aminoguanidine 35
DEX 34
BH4 33
Colistin 32
Forskolin 30
Dial 30
Propofol 29
Meth 28
Activin 28
Fraction 27
Albumin 25
Nephron 25
Angiotensin II 24
ETA 23
CaCl2 23
CaCl2 23
CaCl2 23
EE2 23
CAM 23
Portal 22
Simvastatin 21
CTX 21
BTC 21
ALA 21
EPA 21
citric acid 21
CTX 21
FAD 20
IL-11 20
Emodin 20
Emodin 20
Methylene blue 20
Retinoic acid 19
Fluorescein 19
TiO2 19
balanced salt solution 19
Rolipram 18
Lovastatin 18
more...
Enzyme
mitogen-activated protein kinase 3245
NO synthase 1523
peroxidase 1050
superoxide dismutase 844
protein kinase 802
ERK 802
luciferase 627
protein kinase C 617
alanine aminotransferase 616
caspase-3 524
catalase 472
aspartate aminotransferase 461
NOS 428
caspase-1 410
lysozyme 366
IKK 348
lactate dehydrogenase 348
thrombin 321
NADPH oxidase 315
reverse transcriptase 310
NADPH oxidase 305
alkaline phosphatase 287
MIP 280
focal adhesion kinase 279
trypsin 251
phospholipase A2 245
collagenase 233
glutathione peroxidase 229
MEK 223
phosphodiesterase 219
heme oxygenase 201
AMP-activated protein kinase 183
phosphatidylinositol 3-kinase 181
proteasome 181
elastase 168
ACS 157
phospholipase C 157
ATPase 153
arginase 152
RNA polymerase 137
guanylate cyclase 131
tyrosine hydroxylase 131
proteinase K 127
lipoxygenase 124
xanthine oxidase 122
RNase 121
APC 118
RNase 117
AST 113
thromboplastin 107
MAP 104
AMPK 103
acid phosphatase 101
neutrophil elastase 99
PARP 99
adenylate cyclase 96
caspase-11 89
acetylcholinesterase 89
phosphoinositide 3-kinase 88
caspase-11 88
caspase-8 85
transcriptase 85
calcineurin 84
renin 81
AMPK 80
GSK 78
lipase 74
urokinase-type plasminogen activator 74
glutathione S-transferase 73
neuraminidase 66
NQO1 65
tissue plasminogen activator 62
plasmin 61
matrix metalloproteinase 9 58
cathepsin K 57
MMP-3 57
creatine kinase 57
indoleamine 2,3-dioxygenase 56
histidine decarboxylase 55
caspase-9 55
more...
Compound
nitric oxide 6920
TNF 5231
Dec 4391
DNA 3124
oxygen 2787
Clin 2190
water 1828
sodium 1627
acetate 1619
arginine 1511
glucose 1475
calcium 1403
phosphate 1185
galactose 1167
THP 1139
THP 1137
sulfate 1042
ethanol 804
PGE 794
nitrogen 685
iron 660
hydrogen 595
PGE2 590
ATP 590
tyrosine 557
cAMP 512
cysteine 511
phenol 506
lysine 487
SDS 474
nitrate 442
GSH 427
GSH 427
Phe 415
leucine 413
heptose 412
heptose 412
heptose 412
MTT 382
serine 366
urea 351
zinc 315
methanol 303
alanine 294
H2O2 293
salt 282
methionine 273
glutamate 268
AMP 263
acetic acid 260
silver 251
cGMP 248
GlcNAc 242
thioglycollate 241
creatinine 238
PMA 232
CO2 220
tryptophan 220
NH2 214
PMA 210
Dexamethasone 208
tryptophan 207
bromide 205
tryptophan 202
tryptophan 202
hexose 202
potassium 199
EDTA 198
EDTA 196
N-acetylcysteine 188
ADP 183
ethyl acetate 182
prostacyclin 179
DBA 178
copper 177
ACTH 176
DBA 169
DBA 168
ADP 167
ADP 164
more...