Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P43026 (
lipopolysaccharide
)
62,215
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
lipopolysaccharide
62215
cytokine
8488
tumor necrosis factor
8035
IL-6
5465
TNF
5231
LPS
4418
Sep
4098
TLR4
3859
inducible nitric oxide synthase
3838
Mol
3800
interleukin-6
2456
IL-10
2363
interferon
2188
nitric oxide synthase
2180
TNF-alpha
2100
interferon-gamma
2082
tumor necrosis factor alpha
1992
p38
1914
IL-8
1767
p65
1730
IL-1
1700
cyclooxygenase-2
1642
CD14
1510
Pseudomonas
1450
NMR
1450
THP
1136
COX-2
1105
IFN
1099
chemokine
1088
gut
1084
IL-1 beta
1081
IFN-gamma
1066
IL-4
1027
cyclooxygenase
932
MAPK
914
myeloperoxidase
867
TLR2
834
Cytokine
827
JNK
803
galactosamine
753
more...
Disease
sepsis
3117
sepsis
3012
cancer
1765
tumor
1743
bacterial infection
743
depression
682
atherosclerosis
657
Alzheimer's disease
629
infectious diseases
589
arthritis
581
plaque
580
obesity
528
rheumatoid arthritis
519
diabetes
514
periodontitis
492
Parkinson's disease
480
endotoxic shock
478
Klebsiella
467
cholera
462
BDC
459
asthma
439
ischemia
427
SDS
411
GSH
402
colitis
395
Yersinia
379
HIV
377
Infection
334
pneumonia
331
Haemophilus
325
immunodeficiency
321
Mycobacterium
314
leukemia
312
NAME
306
Brucella abortus
288
pertussis
288
cystic fibrosis
282
MIP
280
pulmonary edema
278
inflammatory bowel disease
270
more...
Symptom
pain
457
respiratory distress
322
diarrhea
272
hypothermia
210
anorexia
183
anesthesia
130
seizures
81
collapse
80
starvation
71
splenomegaly
65
cachexia
61
hyperoxia
56
fatigue
50
acute stress
47
vomiting
40
lethargy
39
cough
37
functional recovery
36
analgesia
33
headache
32
exhaustion
31
nausea
24
acidity
22
abdominal pain
20
tremor
20
weakness
19
Ill
19
arthralgia
18
overweight
18
tachypnea
17
despair
17
erythema
16
HSA
15
memory loss
15
insomnia
13
twitching
13
sleepiness
13
discomfort
12
discomfort
12
agitation
12
more...
Drug
IFN-gamma
1023
IL-2
609
CSF
453
lysine
348
ROS
317
Indomethacin
156
MAP
139
Gel
137
Dermatol
128
IFN-beta
109
Cardiovasc
98
Nitric Oxide
97
vitamin E
95
ascorbate
87
Heme
79
IL-1ra
78
p75
77
Leaf
76
TAK
76
G-CSF
69
lactose
67
Bifidobacterium
66
Monit
65
Ethanol
64
NADH
60
MOF
57
ampicillin
55
Nephron
52
NAG
51
Histamine
50
Asthma
49
CCL
49
ICI
49
Glutathione
47
caffeine
45
Glycyrrhiza
41
CTX
40
MIL
39
Taxol
38
ABC
38
more...
Enzyme
mitogen-activated protein kinase
3245
NO synthase
1523
peroxidase
1050
superoxide dismutase
844
ERK
802
protein kinase
802
luciferase
627
protein kinase C
617
alanine aminotransferase
616
caspase-3
524
catalase
472
aspartate aminotransferase
461
NOS
428
caspase-1
410
lysozyme
366
lactate dehydrogenase
348
IKK
348
thrombin
321
NADPH oxidase
315
reverse transcriptase
310
NADPH oxidase
305
alkaline phosphatase
287
MIP
280
focal adhesion kinase
279
trypsin
251
phospholipase A2
245
collagenase
233
glutathione peroxidase
229
MEK
223
phosphodiesterase
219
heme oxygenase
201
AMP-activated protein kinase
183
phosphatidylinositol 3-kinase
181
proteasome
181
elastase
168
ACS
157
phospholipase C
157
ATPase
153
arginase
152
RNA polymerase
137
more...
Compound
nitric oxide
6920
TNF
5231
Dec
4391
DNA
3124
oxygen
2787
Clin
2190
water
1828
sodium
1627
acetate
1619
arginine
1511
glucose
1475
calcium
1403
phosphate
1185
galactose
1167
THP
1139
THP
1137
sulfate
1042
ethanol
804
PGE
794
nitrogen
685
iron
660
hydrogen
595
ATP
590
PGE2
590
tyrosine
557
cAMP
512
cysteine
511
phenol
506
lysine
487
SDS
474
nitrate
442
GSH
427
GSH
427
Phe
415
leucine
413
heptose
412
heptose
412
heptose
412
MTT
382
serine
366
more...