Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P43026 (lipopolysaccharide)
 62,215 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lipopolysaccharide 62215
cytokine 8488
tumor necrosis factor 8035
IL-6 5465
TNF 5231
LPS 4418
Sep 4098
TLR4 3859
inducible nitric oxide synthase 3838
Mol 3800
interleukin-6 2456
IL-10 2363
interferon 2188
nitric oxide synthase 2180
TNF-alpha 2100
interferon-gamma 2082
tumor necrosis factor alpha 1992
p38 1914
IL-8 1767
p65 1730
IL-1 1700
cyclooxygenase-2 1642
CD14 1510
NMR 1450
Pseudomonas 1450
THP 1136
COX-2 1105
IFN 1099
chemokine 1088
gut 1084
IL-1 beta 1081
IFN-gamma 1066
IL-4 1027
cyclooxygenase 932
MAPK 914
myeloperoxidase 867
TLR2 834
Cytokine 827
JNK 803
galactosamine 753
superoxide dismutase 712
insulin 699
caspase-3 686
mitogen-activated protein 661
CD4 651
ERK 639
ERK1 632
membrane protein 628
lymphoid 623
collagen 608
IL-2 607
IgA 593
ATP 586
thymus 574
MyD88 566
heme oxygenase-1 546
interleukin-10 541
CD86 525
extracellular signal-regulated kinase 516
c-Jun 510
interleukin 6 492
CD40 491
interferon gamma 479
MCP-1 473
CD11b 466
granulocyte 460
p38 mitogen-activated protein kinase 457
macrophage colony-stimulating factor 443
albumin 428
AP-1 420
catalase 416
polypeptide 415
glycoprotein 412
SDS 410
IL-1 alpha 406
GSH 402
CD80 391
Tumor necrosis factor 390
tissue factor 388
alanine aminotransferase 382
granulocyte-macrophage colony-stimulating factor 382
p50 378
lectin 375
MD-2 372
ICAM-1 367
glucan 363
lysozyme 360
aspartate aminotransferase 352
interleukin-4 351
serum albumin 345
NLRP3 335
glucosamine 334
thrombin 327
CD8 326
IL-18 325
lactate dehydrogenase 321
interleukin-2 320
ROS 317
major histocompatibility complex 315
adhesion molecule 305
vascular cell adhesion molecule-1 293
intercellular adhesion molecule-1 287
alkaline phosphatase 285
COX-1 280
MIP 280
Bcl-2 277
STAT3 277
monocyte chemoattractant protein-1 274
matrix metalloproteinase 272
Nrf2 270
endoplasmic reticulum 270
C-reactive protein 264
RANTES 263
erythroid 260
GM-CSF 257
AKT 256
HO-1 256
E-selectin 253
IL-5 250
CSF 249
cyclooxygenase 2 248
IL-17 244
membrane-bound 244
AMP 244
histone 242
IkappaBalpha 241
PI3K 239
fibrinogen 236
CCL2 233
Gen 229
MHC 226
glutathione peroxidase 226
IL-13 224
A-I 223
IgE 222
glial fibrillary acidic protein 220
vascular endothelial growth factor 219
phosphodiesterase 216
TLR3 216
MMP-9 213
beta-endorphin 212
tyrosine kinase 208
p40 208
HLA-DR 198
CD18 198
IL6 197
SOD 196
peroxisome proliferator-activated receptor 196
IgG3 194
MHC class II 193
CXCL10 192
LPS-binding protein 192
Gal 191
STAT 190
IKK 189
lymphokine 183
CD11c 182
phosphatidylinositol 3-kinase 181
PBS 181
MIP-1alpha 181
more...
Disease
sepsis 3117
sepsis 3012
cancer 1765
tumor 1743
bacterial infection 743
depression 682
atherosclerosis 657
Alzheimer's disease 629
infectious diseases 589
arthritis 581
plaque 580
obesity 528
rheumatoid arthritis 519
diabetes 514
periodontitis 492
Parkinson's disease 480
endotoxic shock 478
Klebsiella 467
cholera 462
BDC 459
asthma 439
ischemia 427
SDS 411
GSH 402
colitis 395
Yersinia 379
HIV 377
Infection 334
pneumonia 331
Haemophilus 325
immunodeficiency 321
Mycobacterium 314
leukemia 312
NAME 306
Brucella abortus 288
pertussis 288
cystic fibrosis 282
MIP 280
pulmonary edema 278
stroke 270
inflammatory bowel disease 270
periodontal disease 262
chronic obstructive pulmonary disease 248
Chlamydia 246
virus infection 241
mastitis 232
multiple sclerosis 228
hepatitis 227
hepatocellular carcinoma 224
Proteus 217
tuberculosis 213
melanoma 212
Shigella flexneri 209
Bordetella 207
hypertension 198
Shigella 197
systemic lupus erythematosus 197
Spleen 193
peritonitis 189
liver disease 189
tumor growth 187
influenza 185
carcinogenesis 185
cold 182
brucellosis 178
lymphoma 178
NOD 178
cardiovascular disease 176
DBA 170
type 2 diabetes 168
autoimmune disease 163
adult respiratory distress syndrome 163
carcinoma 160
uterus 159
cognitive impairment 159
AIDS 158
Blocking 157
disseminated intravascular coagulation 156
bacteremia 155
osteoarthritis 152
ulcerative colitis 151
glioma 144
adenocarcinoma 143
Crohn's disease 142
tumorigenesis 134
SEM 133
Evans 131
uveitis 129
tetanus 128
cirrhosis 127
memory impairment 126
typhoid 120
encephalomyelitis 120
Shiga 118
meningitis 117
fatty liver 116
Legionella 114
lupus 113
Mycoplasma 113
multiple myeloma 113
lung disease 111
neuroblastoma 111
hypoglycemia 109
colon cancer 108
cerebral ischemia 108
Tumour necrosis 106
Shigella dysenteriae 106
hyperglycemia 105
metabolic syndrome 105
PHA 104
gonococcal 104
malaria 103
glomerulonephritis 101
pseudotuberculosis 101
lupus 101
breast cancer 100
proteinuria 99
graft-versus-host disease 98
lung cancer 96
salmonellosis 96
gastritis 95
psoriasis 94
osteoporosis 92
schizophrenia 92
malnutrition 92
dementia 92
B-cell lymphoma 91
colorectal cancer 89
Brucella melitensis 88
thrombocytopenia 86
Epstein 86
dermatitis 85
toxic shock syndrome 84
leukopenia 84
Shigella sonnei 81
abortion 80
atopic dermatitis 80
tumor progression 78
cytomegalovirus 78
respiratory disease 77
myocardial infarction 77
Shwartzman reaction 76
pancreatitis 76
heart failure 75
metastases 75
mimicry 75
encephalopathy 75
chorioamnionitis 74
pulmonary fibrosis 73
Adhesion 73
autism 72
acute pancreatitis 72
pulmonary hypertension 72
immunotoxicity 71
type 1 diabetes 70
liver fibrosis 69
renal failure 68
hepatitis B 67
Infections 67
major depressive disorder 67
more...
Symptom
pain 457
respiratory distress 322
diarrhea 272
hypothermia 210
anorexia 183
anesthesia 130
seizures 81
collapse 80
starvation 71
splenomegaly 65
cachexia 61
hyperoxia 56
fatigue 50
acute stress 47
vomiting 40
lethargy 39
cough 37
functional recovery 36
analgesia 33
headache 32
exhaustion 31
nausea 24
acidity 22
tremor 20
abdominal pain 20
weakness 19
Ill 19
arthralgia 18
overweight 18
despair 17
tachypnea 17
erythema 16
HSA 15
memory loss 15
sleepiness 13
insomnia 13
twitching 13
pelvic pain 12
discomfort 12
agitation 12
discomfort 12
hypercapnia 11
ataxia 11
thinning 11
chills 10
adipsia 10
flushing 9
low back pain 9
dyspnea 9
angina 9
myalgia 8
acute pain 8
sore throat 8
Neuropathic pain 8
colic 8
microbial colonization 8
hepatomegaly 7
spasm 7
POA 7
paresis 6
polyuria 6
dry eye 6
wheezing 6
urinary frequency 6
bladder pain 6
hepatosplenomegaly 6
bradykinesia 5
back pain 5
oliguria 5
constipation 5
incoordination 4
dental pain 4
nasal congestion 4
muscle cramps 4
ophthalmoplegia 4
intestinal bleeding 4
nausea and vomiting 4
neuralgia 3
prostration 3
Behavioral symptoms 3
fever of unknown origin 3
Wind 3
polydipsia 3
chest pain 3
menopausal symptoms 3
rigors 3
Depressive symptoms 3
cyanosis 3
syncope 3
rhinorrhea 3
bone pain 3
hemoptysis 3
spasticity 3
emaciation 2
hopelessness 2
Stepping 2
hypersomnia 2
Spots 2
joint stiffness 2
asthenia 2
BHS 2
night sweats 2
vertigo 2
impaired motor coordination 2
catarrh 2
cardiovascular impairment 2
apathy 2
dry skin 2
ACHE 2
decreased appetite 2
physical appearance 2
halitosis 2
exertional dyspnea 2
nasal discharge 2
hypoproteinemia 2
neurological disability 2
chest tightness 2
otalgia 1
tonic-clonic seizure 1
Physical findings 1
Fatigability 1
bitter taste 1
enuresis 1
Mental status changes 1
acute abdominal pain 1
facial pain 1
fasciculation 1
Halo 1
Fluctuation 1
feeling of malaise 1
rectal pain 1
Sore 1
Severe diarrhea 1
periorbital edema 1
distraction 1
stigma 1
Nasal inflammation 1
orofacial pain 1
skin damage 1
numbness 1
Circling 1
Scratch 1
ENT 1
cerebellar ataxia 1
abdominal cramps 1
neck pain 1
muscle rigidity 1
Appetite suppression 1
Ear swelling 1
paraparesis 1
pedal edema 1
sneezing 1
shortness of breath 1
snoring 1
CSR 1
aphagia 1
giddiness 1
tenesmus 1
chromosome marker 1
Gastrointestinal symptoms 1
more...
Drug
IFN-gamma 1023
IL-2 609
CSF 453
lysine 348
ROS 317
Indomethacin 156
MAP 139
Gel 137
Dermatol 128
IFN-beta 109
Cardiovasc 98
Nitric Oxide 97
vitamin E 95
ascorbate 87
Heme 79
IL-1ra 78
p75 77
TAK 76
Leaf 76
G-CSF 69
lactose 67
Bifidobacterium 66
Monit 65
Ethanol 64
NADH 60
MOF 57
ampicillin 55
Nephron 52
NAG 51
Histamine 50
CCL 49
Asthma 49
ICI 49
Glutathione 47
caffeine 45
Glycyrrhiza 41
CTX 40
MIL 39
Taxol 38
ABC 38
Asn 37
DNase I 36
Aminoguanidine 35
DEX 34
BH4 33
Colistin 32
Forskolin 30
Dial 30
Propofol 29
Activin 28
Meth 28
Fraction 27
Nephron 25
Albumin 25
Angiotensin II 24
CaCl2 23
EE2 23
CaCl2 23
CAM 23
CaCl2 23
ETA 23
Portal 22
EPA 21
ALA 21
CTX 21
BTC 21
Simvastatin 21
citric acid 21
CTX 21
Emodin 20
Methylene blue 20
FAD 20
Emodin 20
IL-11 20
Retinoic acid 19
TiO2 19
balanced salt solution 19
Fluorescein 19
Rolipram 18
Vitamin E 18
E5564 18
Lovastatin 18
Ginseng 17
ETS 16
DMI 16
MRC 16
Ringer's solution 16
Prednisolone 16
nitroglycerin 15
NBT 15
TAT 14
Silica 14
PTH 14
CDP 14
Fluorescein 14
Glucagon 13
ZnO 13
Rhamnose 13
Parkin 13
Parkin 13
Rutin 13
Hypaque 13
Hypaque 13
Rosiglitazone 12
Mutagen 12
ROC 12
Sodium nitroprusside 12
Doxycycline 11
Vitamin A 11
Budesonide 11
Ulinastatin 11
CIA 11
Amiloride 11
Myricetin 11
Biopolymers 11
Galactose 11
Adriamycin 11
PCP 11
SiO2 11
OMP 10
NH3 10
Honey 10
Imiquimod 10
Pronase 10
Azithromycin 10
Nimesulide 10
Clodronate 9
Epigallocatechin 9
9-THC 9
Cilostazol 9
Adenosine triphosphate 9
Captopril 9
Amiloride 9
Bosentan 8
Bosentan 8
Ouabain 8
Alanine 8
Methylprednisolone 8
-deoxyadenosine 8
IPM 8
Flunixin meglumine 8
uPA 7
3-Methyladenine 7
TAC 7
Auranofin 7
Tacrolimus 7
AMC 7
Itraconazole 7
Sesamol 7
Xanthium 7
Anakinra 7
Troglitazone 7
TMS 7
PCB 7
Ginger 7
Iloprost 7
niacin 7
ADM 7
Theophylline 6
Bestatin 6
more...
Enzyme
mitogen-activated protein kinase 3245
NO synthase 1523
peroxidase 1050
superoxide dismutase 844
protein kinase 802
ERK 802
luciferase 627
protein kinase C 617
alanine aminotransferase 616
caspase-3 524
catalase 472
aspartate aminotransferase 461
NOS 428
caspase-1 410
lysozyme 366
IKK 348
lactate dehydrogenase 348
thrombin 321
NADPH oxidase 315
reverse transcriptase 310
NADPH oxidase 305
alkaline phosphatase 287
MIP 280
focal adhesion kinase 279
trypsin 251
phospholipase A2 245
collagenase 233
glutathione peroxidase 229
MEK 223
phosphodiesterase 219
heme oxygenase 201
AMP-activated protein kinase 183
phosphatidylinositol 3-kinase 181
proteasome 181
elastase 168
ACS 157
phospholipase C 157
ATPase 153
arginase 152
RNA polymerase 137
tyrosine hydroxylase 131
guanylate cyclase 131
proteinase K 127
lipoxygenase 124
xanthine oxidase 122
RNase 121
APC 118
RNase 117
AST 113
thromboplastin 107
MAP 104
AMPK 103
acid phosphatase 101
neutrophil elastase 99
PARP 99
adenylate cyclase 96
caspase-11 89
acetylcholinesterase 89
caspase-11 88
phosphoinositide 3-kinase 88
transcriptase 85
caspase-8 85
calcineurin 84
renin 81
AMPK 80
GSK 78
urokinase-type plasminogen activator 74
lipase 74
glutathione S-transferase 73
neuraminidase 66
NQO1 65
tissue plasminogen activator 62
plasmin 61
matrix metalloproteinase 9 58
cathepsin K 57
creatine kinase 57
MMP-3 57
indoleamine 2,3-dioxygenase 56
histidine decarboxylase 55
caspase-9 55
chloramphenicol acetyltransferase 54
succinate dehydrogenase 54
glutathione reductase 52
beta-glucuronidase 48
MEKK1 48
beta-galactosidase 47
urease 45
urease 45
ornithine decarboxylase 44
DNase 43
cathepsin B 43
lipoprotein lipase 42
MDP 41
complex I 41
ACE 40
pepsin 40
MMP 40
kallikrein 40
ceruloplasmin 38
beta-lactamase 38
P-glycoprotein 37
prostaglandin synthetase 36
4-epimerase 36
ribonuclease 35
peroxiredoxin 35
caspase-4 35
phospholipase D 35
ribonuclease 35
endonuclease 34
caspase-4 34
gamma-glutamyl transpeptidase 33
cholinesterase 33
glyceraldehyde-3-phosphate dehydrogenase 32
bromelain 32
factor C 32
PDE 32
transglutaminase 32
NADPH-diaphorase 31
glyceraldehyde-3-phosphate dehydrogenase 30
tyrosinase 30
pyruvate dehydrogenase 29
papain 29
GTP cyclohydrolase I 29
cathepsin G 29
chymotrypsin 29
MPP 28
diamine oxidase 27
DNA polymerase 26
glucose-6-phosphate dehydrogenase 26
gamma-glutamylcysteine synthetase 26
matrix metalloproteinase 2 26
interstitial collagenase 26
hexosaminidase 26
soluble epoxide hydrolase 25
demethylase 25
thromboxane synthase 25
histone acetyltransferase 25
glutamine synthetase 24
Pla 24
myosin light chain kinase 24
glyceraldehyde-3-phosphate dehydrogenase 23
granzyme B 23
diaphorase 23
BAL 23
cytochrome oxidase 23
argininosuccinate synthetase 23
sialyltransferase 22
sialyltransferase 22
glyceraldehyde-3-phosphate dehydrogenase 22
sialyltransferase 22
protein phosphatase 2A 22
choline acetyltransferase 22
glyceraldehyde-3-phosphate dehydrogenase 22
CD10 21
chitinase 21
adenosine deaminase 20
adenosine deaminase 20
phosphomannomutase 20
hyaluronidase 20
phosphoglucomutase 20
more...
Compound
nitric oxide 6920
TNF 5231
Dec 4391
DNA 3124
oxygen 2787
Clin 2190
water 1828
sodium 1627
acetate 1619
arginine 1511
glucose 1475
calcium 1403
phosphate 1185
galactose 1167
THP 1139
THP 1137
sulfate 1042
ethanol 804
PGE 794
nitrogen 685
iron 660
hydrogen 595
ATP 590
PGE2 590
tyrosine 557
cAMP 512
cysteine 511
phenol 506
lysine 487
SDS 474
nitrate 442
GSH 427
GSH 427
Phe 415
leucine 413
heptose 412
heptose 412
heptose 412
MTT 382
serine 366
urea 351
zinc 315
methanol 303
alanine 294
H2O2 293
salt 282
methionine 273
glutamate 268
AMP 263
acetic acid 260
silver 251
cGMP 248
GlcNAc 242
thioglycollate 241
creatinine 238
PMA 232
tryptophan 220
CO2 220
NH2 214
PMA 210
Dexamethasone 208
tryptophan 207
bromide 205
hexose 202
tryptophan 202
tryptophan 202
potassium 199
EDTA 198
EDTA 196
N-acetylcysteine 188
ADP 183
ethyl acetate 182
prostacyclin 179
DBA 178
copper 177
ACTH 176
DBA 169
DBA 168
ADP 167
ADP 164
xylose 163
noradrenaline 161
BCG 159
glutamine 158
threonine 158
chloroform 158
ACS 156
ACS 156
retinoic acid 152
pyrrolidine 151
Curcumin 146
MDA 142
His 141
Indomethacin 141
iodine 139
ammonium 139
pyrrolidine 135
PEG 134
glycerol 133
NADPH 132
NADPH 131
Gly 130
dUTP 126
nicotinamide 122
COX 120
NAD 120
Mg2+ 116
GalNAc 115
UDP 113
hexose 112
hexose 112
hexose 112
benzene 111
Polymyxin B 110
5-HT 109
MAP 108
Asp 108
NO3 105
hydroxide 105
MIC 104
proline 103
vitamin D 102
MEK 100
NAD 99
TOF 99
palmitic acid 98
acetone 94
Melatonin 93
HCl 90
ASC 90
uridine 89
titanium 88
DMSO 87
Nitrite 87
ornithine 86
hexane 86
ornithine 86
ornithine 86
ornithine 86
ornithine 86
Nitrite 86
Heme 86
PEG 85
MPTP 84
aluminum 83
Resveratrol 83
Poly I 83
D-glucosamine 82
Triton X-100 82
phosphorus 82
kaempferol 81
DPPH 81
aldehyde 80
Insulin 80
tin 76
diacetate 75
GM1 75
nickel 73
manganese 73
pyridine 72
more...