Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UNIPROT:P43026 (lipopolysaccharide)
 62,215 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An in vitro comparison of the heat exchange properties of the Electromedics D1081A, Sarns MP-4 'Conducer Coil' 165720, Bentley HE-100 and the Shiley BCD Plus 4: 1 blood cardioplegia sets was performed. The efficiency was calculated for each heat exchanger and post-heat exchange blood path temperatures were compared. The calculated efficiency for each heat exchanger is as follows: Electromedics D1081A at 18 l/minute coil water flow (0.95); Sarns MP-4 165720 at 9 l/minute coil water flow (0.93); Bentley HE-100 at 10 l/minute coil water flow (0.91); Shiley BCD Plus at 15 l/minute coil water flow (0.90). Blood path, precoil temperatures for each unit were compared statistically with no differences found (p > 0.05). Blood side, postcoil temperatures were then compared. The average postcoil blood path temperature of the Electromedics D1081A was 1.6 degrees +/- 0.1 degree C, of the Sarns MP-4 165720 it was 2.1 degrees +/- 0.1 degree C, of the Bentley HE-100 it was 2.7 degrees +/- 0.3 degree C, and the Shiley BCD Plus 3.0 degrees +/- 0.4 degree C. The results of this experiment indicate that the average postcoil temperature of the Electromedics D1081A was lower than the Sarns MP-4 165720 (p < 0.05) which was lower than that of the Bentley HE-100 (p < 0.05) and Shiley BCD Plus (p < 0.05). No statistical difference was found between the average postcoil temperature of the Bentley HE-100 and the Shiley BDC Plus.
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PMID:Determination and comparison of heat exchange efficiency of four commercially available blood cardioplegia sets. 783 42

We report the enantioselective total synthesis of (+)-lysergic acid using two different strategies, which featured three metal-catalyzed reactions for the construction of the BCD three rings, involving Pd-catalyzed indole synthesis for the construction of the B ring, a ring-closing metathesis reaction for the formation of the D ring, and an intramolecular Heck reaction to forge the C ring. In synthetic strategy I, the synthesis was achieved in 20 steps following the ring construction sequence of BDC. In synthetic strategy II, the synthetic route was shortened to only 12 steps by following the ring construction sequence of DBC and using a 4-chlorotryptophan derivative for the intramolecular Heck reaction. Moreover, we also discussed an unsuccessful synthetic strategy.
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PMID:Total synthesis of (+)-lysergic acid. 2411 83