Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42574 (caspase-3)
45,978 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-3 1.000
caspase-9 0.078
Bcl-2 0.064
caspase-8 0.037
PARP 0.029
cytochrome c 0.024
annexin V 0.011
poly(ADP-ribose) polymerase 0.008
poly (ADP-ribose) polymerase 0.007
Bid 0.006
Fas 0.006
p53 0.005
bax 0.004
anti-apoptotic protein 0.004
XIAP 0.003
Bax protein 0.003
p38 0.003
Apaf-1 0.003
survivin 0.003
apoptosis-inducing factor 0.003
JNK 0.003
bcl-2 0.003
BAX 0.003
CPP32 0.003
pro-apoptotic protein 0.002
ROS 0.002
p21 0.002
Bak 0.002
Mcl-1 0.002
LC3 0.002
AIF 0.002
Smac 0.002
FasL 0.002
caspase 7 0.002
PI3K 0.002
inhibitor of apoptosis 0.002
PARP-1 0.001
AKT 0.001
TNF 0.001
GSH 0.001
superoxide dismutase 0.001
ICAD 0.001
X-linked inhibitor of apoptosis protein 0.001
tumor necrosis factor 0.001
Bcl-X 0.001
calpain 0.001
cyclin D1 0.001
Fas ligand 0.001
ERK1 0.001
cytochrome 0.001
MAPK 0.001
apoptosis-related protein 0.001
lactate dehydrogenase 0.001
ERK 0.001
Beclin-1 0.001
c-Jun 0.001
FADD 0.001
TdT 0.001
GRP78 0.001
DIABLO 0.001
cyclin B1 0.001
C/EBP homologous protein 0.001
proliferating cell nuclear antigen 0.001
p65 0.001
endonuclease G 0.001
inducible nitric oxide synthase 0.001
TRAIL 0.001
CHOP 0.001
catalase 0.001
mTOR 0.001
CD95 0.001
caspase-activated DNase 0.001
protein kinase B 0.001
p27 0.001
LDH 0.001
glutathione peroxidase 0.001
p62 0.001
Mol 0.001
caspase 6 0.001
PUMA 0.001
more...
Disease
cancer 0.002
GSH 0.001
B-cell lymphoma 0.001
tumor 0.001
ischemia 0.001
MCF 0.001
tumor growth 0.001
cerebral ischemia 0.001
neuroblastoma 0.001
colon cancer 0.001
hepatocellular carcinoma 0.000
leukemia 0.000
breast cancer 0.000
DDP 0.000
Alzheimer's disease 0.000
carcinoma 0.000
lung cancer 0.000
MTS 0.000
AGS 0.000
acute promyelocytic leukemia 0.000
prostate cancer 0.000
glioma 0.000
osteosarcoma 0.000
Parkinson's disease 0.000
glioblastoma 0.000
ovarian cancer 0.000
liver cancer 0.000
colorectal cancer 0.000
cervical cancer 0.000
adenocarcinoma 0.000
gastric cancer 0.000
non-small cell lung cancer 0.000
melanoma 0.000
liver cancer 0.000
carcinogenesis 0.000
tumorigenesis 0.000
renal ischemia 0.000
pancreatic cancer 0.000
FAS 0.000
squamous cell carcinoma 0.000
Osteosarcoma 0.000
Osteosarcoma 0.000
brain edema 0.000
myocardial ischemia 0.000
stroke 0.000
diabetic cardiomyopathy 0.000
diabetes 0.000
hyperglycemia 0.000
lymphoma 0.000
retinoblastoma 0.000
memory impairment 0.000
ATM 0.000
chronic myeloid leukemia 0.000
pheochromocytoma 0.000
multiple myeloma 0.000
bladder cancer 0.000
Pineal 0.000
oral cancer 0.000
Blocking 0.000
CEM 0.000
tumor progression 0.000
Reovirus infection 0.000
myeloid leukemia 0.000
liver fibrosis 0.000
solid tumor 0.000
Hepatocellular carcinoma 0.000
acute myeloid leukemia 0.000
Neuroblastoma 0.000
Neuroblastoma 0.000
lung carcinoma 0.000
diabetic nephropathy 0.000
cognitive impairment 0.000
sepsis 0.000
epithelial ovarian cancer 0.000
Middle cerebral artery occlusion 0.000
sepsis 0.000
SCID 0.000
glioblastoma multiforme 0.000
Huntington's disease 0.000
cerebral infarction 0.000
more...
Symptom
collapse 0.000
functional recovery 0.000
starvation 0.000
hyperoxia 0.000
hypothermia 0.000
seizures 0.000
skin damage 0.000
memory loss 0.000
anesthesia 0.000
Anoxia 0.000
neurological disability 0.000
bradykinesia 0.000
Chronic pelvic pain syndrome 0.000
neurological pain 0.000
Scratch 0.000
respiratory distress 0.000
breast hyperplasia 0.000
Motor dysfunction 0.000
thinning 0.000
not coping 0.000
sinus congestion 0.000
cachexia 0.000
diarrhea 0.000
infant diarrhea 0.000
pain 0.000
acute stress 0.000
Ear swelling 0.000
Circling 0.000
startle reaction 0.000
ataxia 0.000
Inflammatory pain 0.000
stomach pain 0.000
abiotrophy 0.000
Behavioral symptoms 0.000
POA 0.000
impaired motor coordination 0.000
dry eye 0.000
incoordination 0.000
Neuropathic pain 0.000
Tenderness 0.000
weakness 0.000
HSA 0.000
disturbed balance 0.000
loss of balance 0.000
male subfertility 0.000
exhaustion 0.000
Joint hypermobility 0.000
loss of equilibrium 0.000
tremor 0.000
peri-menopausal 0.000
Decreased activity 0.000
halitosis 0.000
cerebellar ataxia 0.000
forgetfulness 0.000
hyperemesis 0.000
acidity 0.000
chorea 0.000
loss of taste 0.000
hypercapnia 0.000
low back pain 0.000
menopausal symptoms 0.000
sore throat 0.000
joint stiffness 0.000
motor symptom 0.000
hyperesthesia 0.000
abdominal cramps 0.000
ataxic gait 0.000
ketonuria 0.000
personality change 0.000
fatigue 0.000
nasal discharge 0.000
bitter taste 0.000
tachypnea 0.000
erythema 0.000
limb pain 0.000
physical appearance 0.000
dystonia 0.000
despair 0.000
spasticity 0.000
vomiting 0.000
more...
Drug
ROS 0.002
Arsenic trioxide 0.000
AMC 0.000
3-Methyladenine 0.000
CED 0.000
Emodin 0.000
Edratide 0.000
TTC 0.000
Emodin 0.000
Bortezomib 0.000
Lexatumumab 0.000
Etoposide 0.000
MAP 0.000
Simvastatin 0.000
Sorafenib 0.000
Taxol 0.000
p75 0.000
PFT 0.000
Glycyrrhiza 0.000
Teroxirone 0.000
Ethanol 0.000
CA-074 0.000
Propidium 0.000
Ulinastatin 0.000
Flavopiridol 0.000
Epigallocatechin 0.000
vitamin E 0.000
Alsterpaullone 0.000
2-Iminobiotin 0.000
NVP 0.000
Scutellaria root 0.000
Glutathione 0.000
ascorbate 0.000
Senega 0.000
Purvalanol 0.000
Alisma rhizome 0.000
Condurango 0.000
2-Methoxyestradiol 0.000
Monit 0.000
Rutin 0.000
Propofol 0.000
Ginseng 0.000
Tezacitabine 0.000
Aquasol A 0.000
Mapatumumab 0.000
ADR 0.000
MRC 0.000
Imatinib 0.000
TAT 0.000
Advexin 0.000
Saccharin sodium 0.000
P-Nitrophenol 0.000
Liraglutide 0.000
Parkin 0.000
Parkin 0.000
Phosphatidylserine 0.000
Heme 0.000
Rasagiline 0.000
Hyperforin 0.000
CoCl2 0.000
CoCl2 0.000
Docetaxel 0.000
Oxaliplatin 0.000
Montirelin 0.000
ICI 0.000
Mevastatin 0.000
Myricetin 0.000
Fidarestat 0.000
Fidarestat 0.000
Gefitinib 0.000
IL-2 0.000
CPT-11 0.000
Benzoic Acid 0.000
7,8-Dihydroneopterin 0.000
Zebularine 0.000
IFN-gamma 0.000
Indomethacin 0.000
Fluorescein 0.000
VCR 0.000
Diammonium glycyrrhizinate 0.000
more...
Enzyme
caspase-3 0.764
caspase-9 0.066
caspase-8 0.031
PARP 0.028
caspase-7 0.007
caspase-7 0.007
mitogen-activated protein kinase 0.004
caspase-6 0.003
caspase-6 0.003
caspase-2 0.002
caspase-2 0.002
superoxide dismutase 0.002
caspase-1 0.002
lactate dehydrogenase 0.001
catalase 0.001
glutathione peroxidase 0.001
TdT 0.001
ERK 0.001
caspase-4 0.001
protein kinase 0.001
GSK 0.000
caspase-4 0.000
caspase-10 0.000
caspase-10 0.000
phosphatidylinositol 3-kinase 0.000
MEK 0.000
MPP 0.000
Omi/HtrA2 0.000
cdc2 0.000
alanine aminotransferase 0.000
aspartate aminotransferase 0.000
proteasome 0.000
phosphoinositide 3-kinase 0.000
AMP-activated protein kinase 0.000
luciferase 0.000
focal adhesion kinase 0.000
m-calpain 0.000
mu-calpain 0.000
AMPK 0.000
NADPH oxidase 0.000
protein kinase C 0.000
NADPH oxidase 0.000
cathepsin B 0.000
granzyme B 0.000
MMP 0.000
AST 0.000
AMPK 0.000
caspase-11 0.000
heme oxygenase 0.000
caspase-11 0.000
creatine kinase 0.000
glutathione reductase 0.000
complex I 0.000
peroxidase 0.000
cathepsin D 0.000
IKK 0.000
tyrosine hydroxylase 0.000
neutral sphingomyelinase 0.000
topoisomerase 0.000
NO synthase 0.000
topoisomerase 0.000
glutathione S-transferase 0.000
MAP 0.000
calcineurin 0.000
NQO1 0.000
P-glycoprotein 0.000
NOS 0.000
MEKK1 0.000
thioredoxin reductase 0.000
caspase-5 0.000
holocytochrome c synthetase 0.000
acetylcholinesterase 0.000
PDK1 0.000
DCF 0.000
ATPase 0.000
DNA ligase 0.000
DNA ligase 0.000
caspase-5 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
collagenase 0.000
more...
Compound
dUTP 0.007
MTT 0.006
ADP-ribose 0.002
oxygen 0.002
DNA 0.002
TNF 0.001
GSH 0.001
GSH 0.001
MDA 0.001
Hoechst 33342 0.001
N-acetylcysteine 0.001
iodine 0.001
Cyt 0.000
DDP 0.000
Cytochrome c 0.000
Asp 0.000
bromide 0.000
cysteine 0.000
MPP 0.000
MPP 0.000
Curcumin 0.000
nitric oxide 0.000
H2O2 0.000
acridine 0.000
ADR 0.000
MTS 0.000
glucose 0.000
ATP 0.000
Resveratrol 0.000
8-OHdG 0.000
Tanshinone 0.000
Oridonin 0.000
Adriamycin 0.000
MEK 0.000
Quercetin 0.000
DCB 0.000
DCB 0.000
DCB 0.000
calcium 0.000
ADP 0.000
Neuronal 0.000
CAT 0.000
CAT 0.000
CAT 0.000
Dec 0.000
diacetate 0.000
Berberine 0.000
DCB 0.000
Ursolic acid 0.000
ADP 0.000
ADP 0.000
ATF 0.000
glutamate 0.000
NOXA 0.000
DCB 0.000
hydrogen 0.000
Baicalin 0.000
Chrysin 0.000
Hematoxylin 0.000
GSSG 0.000
CMK 0.000
Staurosporine 0.000
Baicalein 0.000
serine 0.000
Sulforaphane 0.000
Staurosporine 0.000
Silymarin 0.000
Bongkrekic acid 0.000
3-Methyladenine 0.000
creatinine 0.000
Triptolide 0.000
Melatonin 0.000
XTT 0.000
Luteolin 0.000
Puerarin 0.000
Bufalin 0.000
Panam 0.000
Rotenone 0.000
Matrine 0.000
Matrine 0.000
more...