Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42574 (caspase-3)
 45,978 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

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Human Gene/Protein
caspase and RIP adapter with death domain 9.4
ACIN1 protein 9.4
Homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein 9.4
interleukin-12 p35 subunit 9.4
Rh family, C glycoprotein 9.4
TNFRSF6 protein 9.4
zinc finger protein 224 9.4
H2BFM 9.4
caspase-3 9.4
Minichromosome maintenance complex component 3 9.4
ALS2CR7 9.4
DDX46 protein 9.4
LASS5 protein 9.4
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 9.4
PLA2G16 protein 9.4
C1orf201 9.4
IRX5 protein 9.4
manic fringe homolog 9.4
hect domain and RLD 5 9.4
ubiquitin specific protease 47 9.4
gamma-glutamyltransferase 2 9.4
Glyoxylate reductase/hydroxypyruvate reductase 9.4
zinc finger protein 800 9.4
DAGD 9.4
ubiquitin specific protease 2 9.4
LOC401317 9.4
Death associated protein 3 9.4
BRI3-binding protein 9.4
Apoptotic peptidase activating factor 1 9.4
tetratricopeptide repeat domain 9C 9.4
troponin I, cardiac 9.4
TXNL5 9.4
Mst3 and SOK1-related kinase 9.4
AMPH1 9.4
p21, Cip1 8.9
DFF35 8.8
caspase-9 8.7
Caspase-activated DNase 8.5
caspase 7 8.4
tropomyosin 3 isoform 2 8.4
GCK family kinase 8.4
p21 protein (Cdc42/Rac)-activated kinase 3 8.4
transmembrane protein 117 8.4
death inducer-obliterator 1 8.4
Transient receptor potential cation channel, subfamily V, member 1 8.4
Sal-like 4 (Drosophila) 8.4
rho family, small GTP binding protein Rac1 8.4
G protein-coupled receptor 34 8.4
bridging integrator 2 8.4
Polypeptide N-acetylgalactosaminyltransferase 14 8.4
MAX interactor 1 8.4
sterile alpha motif and leucine zipper containing kinase AZK 8.4
C4orf22 8.4
WNK lysine deficient protein kinase 2 8.4
TBC1D19 8.4
Prune homolog 2 (Drosophila) 8.4
anti-Mullerian hormone receptor type II 8.4
XKR8 8.4
Engulfment and cell motility protein 1 8.4
RNA binding motif protein 25 8.4
RAN binding protein 9 8.4
RING finger protein 121 8.4
mitochondrial ubiquitin ligase activator of NFKB 1 8.4
Cell death activator 8.4
D4S234E 8.4
glutamate-rich 1 8.4
TDE1 8.4
DPYSL3 protein 8.4
LGP1 8.4
caspase-8 8.2
ICAD 8.2
caspase-activated DNase 8.1
apoptosis related protein 8.1
poly (ADP-ribose) polymerase 8.1
CPP32 8.1
NAIP protein 8.0
CDK5 protein 8.0
DFF40 8.0
PRAP 8.0
apoptosis-related protein 8.0
more...
Disease
Bovine tritrichomonosis 8.4
Infantile Krabbe disease 7.9
Non-bacterial prostatitis 7.9
Nutritional muscular dystrophy 7.9
DFNA24 7.9
Exudative diathesis 7.9
HMN7B 7.4
PFM2 7.4
POF4 7.4
Eimeriosis 7.1
Alcoholic liver damage 7.1
Reovirus infection 7.1
Retinal microaneurysms 7.1
recurrent gallbladder cancer 6.9
RCMD-RS 6.9
nutmeg liver 6.6
Ischemic cerebral infarction 6.6
Radiocontrast nephropathy 6.6
Brain Ischemia 6.6
Malignant insulinoma 6.4
Teratospermia 6.4
Diabetic encephalopathy 6.3
DFNA5 6.3
Neonatal pneumonia 6.3
Impaired social interaction 6.3
Neonatal necrotizing enterocolitis 6.3
Fowl cholera 6.2
Proteus mirabilis infection 6.1
endometrial adenoacanthoma 6.1
Coliform mastitis 6.1
DECD 6.1
cerebral ischemia/hypoxia 6.0
Middle cerebral artery occlusion 5.9
Hypoxic-ischemic brain injury 5.8
lung sarcoma 5.7
ADLTE 5.7
Neonatal anoxia 5.6
neck neoplasm 5.6
androgen independent prostate cancer 5.6
Thromboembolic stroke 5.5
Hereditary periodic fever 5.5
Intestinal ischemia 5.5
AGS 5.5
Testicular torsion 5.5
IHG 5.4
methionine synthase deficiency 5.4
oral neoplasm 5.4
Hypoxic-ischemic encephalopathy (HIE) 5.4
Glycogen storage disease type Ib 5.4
Retinal ischemia 5.4
MTS 5.4
heterophyiasis 5.3
B-cell lymphoma 5.3
DEND 5.2
Granular corneal dystrophy 5.2
salivary gland adenoid cystic carcinoma 5.2
NINA 5.2
metastatic follicular thyroid cancer 5.2
Zar 5.2
gastric cancer stage 5.2
Viral myocarditis 5.2
colon neoplasm 5.2
testicular dysfunction 5.1
Myelokathexis 5.1
Progression of prostate cancer 5.1
Critical illness myopathy 5.1
Postoperative cognitive dysfunction 5.1
Avian encephalomyelitis 5.0
CGL2 5.0
pediatric liver cancer 5.0
DDP 5.0
mouse leukemia L1210 5.0
Branch retinal vein occlusion 5.0
diabetic cardiomyopathy 5.0
Transient cerebral ischemia 5.0
renal ischemia 4.9
Silence 4.9
myocardial hypoxia 4.9
Acute respiratory distress 4.9
HIDS 4.9
more...
Symptom
Chronic pelvic pain syndrome 4.6
neurological pain 4.5
breast hyperplasia 4.3
not coping 4.2
sinus congestion 4.1
Motor dysfunction 4.1
infant diarrhea 3.7
skin damage 3.5
Anoxia 3.5
hyperoxia 3.5
Ear swelling 3.5
Circling 3.4
Scratch 3.4
Inflammatory pain 3.2
startle reaction 3.2
functional recovery 3.1
abiotrophy 3.1
Behavioral symptoms 3.1
neurological disability 3.0
collapse 2.9
impaired motor coordination 2.9
memory loss 2.8
disturbed balance 2.6
stomach pain 2.5
Tenderness 2.5
Joint hypermobility 2.5
starvation 2.4
male subfertility 2.4
POA 2.4
bradykinesia 2.3
loss of equilibrium 2.3
loss of balance 2.2
hypothermia 2.0
peri-menopausal 1.9
Neuropathic pain 1.8
incoordination 1.6
cachexia 1.4
dry eye 1.4
Decreased activity 1.4
acute stress 1.4
halitosis 1.2
HSA 1.2
hyperemesis 1.2
forgetfulness 1.0
thinning 1.0
loss of taste 0.9
seizures 0.8
respiratory distress 0.8
motor symptom 0.6
chorea 0.4
joint stiffness 0.4
hyperesthesia 0.4
abdominal cramps 0.4
menopausal symptoms 0.3
ataxic gait 0.3
ketonuria 0.3
personality change 0.3
ataxia 0.3
cerebellar ataxia 0.2
limb pain 0.0
nasal discharge 0.0
exhaustion 0.0
sore throat 0.0
bitter taste -0.0
anesthesia -0.1
physical appearance -0.1
diarrhea -0.2
despair -0.2
tachypnea -0.3
clubbing -0.4
tremor -0.4
DNA marker -0.4
weakness -0.5
hypercapnia -0.5
otalgia -0.5
twitching -0.6
microbial colonization -0.6
eds -0.6
muscle rigidity -0.6
low back pain -0.7
more...
Drug
Edratide 9.4
Senega 8.4
Lexatumumab 8.4
Alisma rhizome 8.4
Condurango 8.4
Teroxirone 8.1
Aquasol A 7.9
2-Iminobiotin 7.9
Tezacitabine 7.9
P-Nitrophenol 7.4
Saccharin sodium 7.4
Alsterpaullone 7.4
Montirelin 7.1
Mapatumumab 7.1
Scutellaria root 7.0
Advexin 7.0
Purvalanol 6.9
Benzoic Acid 6.9
Tandutinib 6.6
Visilizumab 6.6
Diammonium glycyrrhizinate 6.6
3-Methyladenine 6.6
Alexidine 6.4
7,8-Dihydroneopterin 6.4
Cassia seed 6.3
Bupleurum root 6.3
Balhimycin 6.3
Angelica dahurica root 6.3
Fidarestat 6.2
Fidarestat 6.2
Limaprost 6.1
3-Methoxybenzamide 6.1
Proflavin 6.1
Lemon oil 6.1
Zedoary 6.1
CA-074 6.1
Ulinastatin 6.1
Mevastatin 6.0
Bear bile 6.0
Bv2 6.0
Epothilone B 5.9
Avasimibe 5.9
Flurbiprofen axetil 5.7
Lestaurtinib 5.7
Azilect 5.7
Arsenic trioxide 5.7
Berberine chloride 5.7
ROS 5.7
Flavopiridol 5.7
2-Methoxyestradiol 5.6
Emodin 5.6
Sodium phenylbutyrate 5.6
Zebularine 5.6
CED 5.6
Sodium metabisulfite 5.6
Platonin 5.5
Fasudil hydrochloride 5.5
Benidipine hydrochloride 5.5
Propidium 5.5
Polaprezinc 5.5
Irofulven 5.5
Cupric sulfate 5.4
AMC 5.4
Penfluridol 5.4
Hyperforin 5.4
Tolfenamic acid 5.3
Emodin 5.3
Coix seed 5.3
Citrus unshiu peel 5.3
Quinaprilat 5.3
cetrorelix acetate 5.3
Rasagiline 5.3
Teduglutide 5.3
Benfotiamine 5.3
Atractylodes rhizome 5.3
Cilengitide 5.3
Safingol 5.3
Gardenia fruit 5.3
Tacalcitol 5.3
Valpromide 5.2
more...
Enzyme
caspase-3 9.4
caspase-9 8.8
caspase-7 8.7
caspase-7 8.7
holocytochrome c synthetase 8.4
caspase-6 8.4
caspase-6 8.4
caspase-8 8.3
caspase-2 8.0
caspase-2 8.0
caspase-10 7.8
caspase-10 7.8
PARP 7.7
caspase-4 7.4
caspase-4 7.4
Omi/HtrA2 7.1
cystine reductase 6.9
D-2-hydroxy acid dehydrogenase 6.4
TdT 6.4
caspase-1 6.2
caspase-5 6.2
caspase-11 6.2
caspase-11 6.1
mu-calpain 6.1
m-calpain 6.0
caspase-5 5.9
MPP 5.9
ceramide synthetase 5.8
calpain 10 5.8
GalT-4 5.6
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.4
BCKA 5.3
neutral sphingomyelinase 5.3
GSK 5.3
HPRP 5.3
phenylpyruvate tautomerase 5.3
MT 1 5.2
aspartate dehydrogenase 5.2
mitogen-activated protein kinase 5.0
granzyme B 4.9
lactate dehydrogenase 4.8
phosphoinositide 3-kinase 4.8
cdc2 4.8
inositol 3-kinase 4.8
superoxide dismutase 4.8
cathepsin B 4.7
sphingomyelin synthase 4.7
phosphatidylinositol 3-kinase 4.7
glutathione peroxidase 4.6
HK3 4.6
MMP 4.6
ceramidase 4.5
AMPK 4.5
HK2 4.4
DNase II 4.4
2,3-bisphosphoglycerate phosphatase 4.4
palmitoyl-protein thioesterase 4.4
heme oxygenase 4.4
MHCK 4.3
SNO 4.3
aspartase 4.3
AST 4.3
sphingosine kinase 4.3
L-amino-acid oxidase 4.3
AO1 4.3
MEK 4.3
AMP-activated protein kinase 4.2
isochorismatase 4.2
proteinase-3 4.2
catalase 4.2
3-hydroxyisobutyrate dehydrogenase 4.2
3-hydroxy-3-methylglutaryl-CoA lyase 4.2
MEKK1 4.1
glucosylceramide synthase 4.1
cathepsin D 4.1
NADPH oxidase 4.1
NADPH oxidase 4.1
granzyme K 4.0
STK4 4.0
aspartate aminotransferase 4.0
more...
Compound
C26H30O6 9.4
C25H28O6 9.4
2-phenylacetylenesulfonamide 9.4
trans-Dihydronarciclasine 9.4
C25H28O6 9.4
Altersolanol A 9.4
C35H36N4O5 9.4
crocetin di-(beta-d-glucosyl)-ester 9.4
crocetin-(beta-d-gentiobiosyl)-(beta-d-glucosyl)-ester 9.4
C25H28O6 9.4
C25H28O6 9.4
Podophyllotoxin acetate 9.4
estra-1,3,5(10)-trien-17-ol 9.4
Iodinin 9.4
C25H28O6 8.4
4-chloro-1H-indole 8.4
Uvaretin 8.4
Lunacridine 8.4
7-Deacetoxy-7-oxogedunin 8.4
4-chloro-N-methylbenzamide 8.4
5H-indeno[1,2-b]pyridin-5-one 8.4
C22H26N2O5 8.4
Lunacridine 8.4
8-Deoxylactucin 8.4
Abyssinone V 8.4
Vitamin K4 8.4
Armepavine 8.4
Dentatin 8.4
Methoxycamptothecin 8.4
Gymnemic acid I 8.4
Pseudolaric acid-B 8.4
Wighteone 8.4
Decylubiquinone 8.1
Sinularin 8.0
Sinulariolide 7.9
11H-indeno[1,2-b]quinoxaline 7.9
Venenatine 7.9
ergosta-7,22-dien-3-ol 7.9
2-Amino-3-hydroxypyridine 7.9
2,5-Dihydrophenylalanine 7.9
Lycopodine 7.9
Vitamin K4 7.9
Ginsenoside Rf 7.9
Aristololactam 7.9
3-Hydroxybiphenyl 7.9
Dracorhodin 7.8
Cassaine 7.6
Jervine 7.6
5,12-naphthacenedione 7.6
Deltonin 7.6
Pachymic acid 7.6
Quinalizarin 7.6
Raddeanin A 7.5
Dehydrocostus lactone 7.5
Bongkrekic acid 7.5
Sarcophine 7.4
Cajanol 7.4
Dehydrodieugenol 7.4
Kinetin riboside 7.4
Gluconasturtiin 7.4
4,6,8-trimethylazulene 7.4
GW 6471 7.4
methyl 3-oxo-3-phenylpropanoate 7.4
Scoulerine 7.4
Murrayanine 7.4
Bellidifolin 7.4
24-Hydroxycholesterol 7.4
Codeinone 7.4
6-methylquinoxaline 7.4
Auriculasin 7.4
Echinocystic acid 7.3
Methyl caffeate 7.3
Obacunone 7.2
dUTP 7.2
Isoalantolactone 7.2
Valtrate 7.1
Vernodalin 7.1
Saucernetin 7.1
N-Phenylmaleimide 7.1
2-hexadecanol 7.1
more...