Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P42574 (caspase-3)
45,978 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein caspase-3 45978 Bcl-2 9955 caspase-9 5818 cytochrome c 5073 p53 4298 Mol 4112 caspase-8 3908 PARP 3807 Sep 2935 annexin V 2173 TNF 2033 p38 1975 Fas 1899 tumor necrosis factor 1785 superoxide dismutase 1726 GSH 1600 JNK 1447 p21 1437 ROS 1415 PI3K 1292 MAPK 1291 poly(ADP-ribose) polymerase 1285 endoplasmic reticulum 1284 AKT 1253 catalase 1245 cytokine 1159 lactate dehydrogenase 1146 ERK 1138 ATP 1109 ERK1 1103 cytochrome 1068 IL-6 1028 bcl-2 962 mTOR 912 cyclin D1 831 inducible nitric oxide synthase 831 Bid 810 survivin 797 glutathione peroxidase 785 poly (ADP-ribose) polymerase 777 insulin 769 c-Jun 749 LC3 735 p65 708 proliferating cell nuclear antigen 703 lipopolysaccharide 686 bax 683 anti-apoptotic protein 671 BAX 637 SOD 611 calpain 567 XIAP 563 LDH 552 Mcl-1 541 collagen 526 proteasome 512 extracellular signal-regulated kinase 511 Bak 504 kit 503 vascular endothelial growth factor 482 FasL 482 Fas ligand 481 p27 480 Bax protein 469 protein kinase B 457 heme oxygenase-1 454 TNF-alpha 439 apoptosis-inducing factor 436 Nrf2 432 CHOP 430 inhibitor of apoptosis 429 ADP 423 phosphatidylinositol 3-kinase 419 PARP-1 415 pro-apoptotic protein 403 catenin 401 Ki-67 401 mitogen-activated protein 397 COX-2 392 glial fibrillary acidic protein 389 more...

Disease cancer 9401 tumor 5993 ischemia 2002 GSH 1601 breast cancer 1495 tumor growth 1455 leukemia 1424 carcinoma 1298 hepatocellular carcinoma 1273 Alzheimer's disease 1116 MCF 1016 diabetes 973 B-cell lymphoma 968 neuroblastoma 862 colon cancer 842 lung cancer 841 prostate cancer 753 Parkinson's disease 741 stroke 727 cerebral ischemia 686 adenocarcinoma 668 melanoma 643 colorectal cancer 597 carcinogenesis 590 tumorigenesis 555 glioma 540 gastric cancer 482 lymphoma 474 ovarian cancer 444 squamous cell carcinoma 432 osteosarcoma 393 cervical cancer 381 non-small cell lung cancer 367 glioblastoma 365 myocardial ischemia 345 liver cancer 325 pancreatic cancer 318 sepsis 315 multiple myeloma 309 sepsis 306 hyperglycemia 306 atherosclerosis 295 tumor progression 295 myocardial infarction 295 acute promyelocytic leukemia 273 acute myeloid leukemia 266 cognitive impairment 263 DDP 253 liver cancer 250 heart failure 235 chronic myeloid leukemia 225 type 2 diabetes 214 lung carcinoma 213 bladder cancer 208 obesity 203 virus infection 202 pheochromocytoma 197 HIV 194 ATM 189 hypertension 182 retinoblastoma 181 depression 178 osteoarthritis 176 metastases 166 cold 166 dementia 165 MTS 162 cardiovascular disease 158 rheumatoid arthritis 151 amyotrophic lateral sclerosis 147 AGS 146 Huntington's disease 144 memory impairment 144 Blocking 144 diabetic nephropathy 143 epithelial ovarian cancer 143 infectious diseases 141 acute lymphoblastic leukemia 138 skin cancer 137 brain edema 131 more...

Symptom collapse 307 seizures 201 starvation 190 functional recovery 169 anesthesia 148 pain 142 hypothermia 99 hyperoxia 83 diarrhea 72 respiratory distress 48 weakness 39 memory loss 36 thinning 33 ataxia 28 skin damage 25 cachexia 22 exhaustion 20 tremor 20 fatigue 18 bradykinesia 17 acute stress 17 acidity 13 vomiting 12 neurological disability 11 analgesia 10 dry eye 10 HSA 10 headache 9 angina 9 Anoxia 9 low back pain 9 overweight 9 abdominal pain 8 hypercapnia 8 incoordination 8 nausea 8 erythema 8 Neuropathic pain 7 cough 7 back pain 6 Scratch 6 cerebellar ataxia 6 dystonia 6 anorexia 6 insomnia 6 dyspnea 5 dizziness 5 splenomegaly 5 spasticity 5 POA 4 chorea 4 hypotonia 4 constipation 4 stomach pain 4 sore throat 4 vertigo 3 hepatomegaly 3 chest pain 3 hepatosplenomegaly 3 loss of balance 3 menopausal symptoms 3 Tenderness 3 tachypnea 3 nausea and vomiting 3 Motor dysfunction 2 male subfertility 2 hemiplegia 2 acute pain 2 disturbed balance 2 halitosis 2 bitter taste 2 agitation 2 exertional dyspnea 2 startle reaction 2 despair 2 pelvic pain 2 ophthalmoplegia 2 tinnitus 2 Decreased activity 2 polyuria 2 more...

Drug ROS 1415 Monit 186 ascorbate 156 MAP 153 vitamin E 142 lysine 137 Dermatol 130 IL-2 122 IFN-gamma 119 Cardiovasc 113 Ethanol 110 Arsenic trioxide 95 Glutathione 75 p75 74 CSF 74 AMC 73 Taxol 67 caffeine 64 TTC 63 CTX 56 Indomethacin 55 Bortezomib 54 ICI 54 Simvastatin 49 MRC 49 ZnO 48 Sorafenib 46 NADH 46 Heme 44 Glycyrrhiza 43 EE2 43 Etoposide 42 Propofol 42 Fluorescein 42 Imatinib 41 CED 40 TAT 40 Angiotensin II 39 Adriamycin 38 ADR 38 Ginseng 36 Emodin 34 Parkin 34 Parkin 34 Emodin 34 NVP 32 Docetaxel 31 CPT-11 30 Vitamin E 30 Mutagen 30 ADM 30 CoCl2 26 CoCl2 26 -deoxyadenosine 25 PFT 25 Leaf 25 ALA 24 Gefitinib 24 Rutin 24 Nitric Oxide 23 CTX 23 lactose 23 CTX 23 3-Methyladenine 23 Lovastatin 22 Oxaliplatin 22 Epigallocatechin 22 Phosphatidylserine 20 Gel 20 Retinoic acid 19 BH4 19 CCL 19 Portal 19 DNase I 19 Photofrin 19 EPA 18 IFN-beta 18 Rosiglitazone 17 Ouabain 17 Silica 17 more...

Enzyme caspase-3 35429 caspase-9 4758 mitogen-activated protein kinase 4383 PARP 4192 caspase-8 3145 superoxide dismutase 2288 ERK 1605 catalase 1443 protein kinase 1371 lactate dehydrogenase 1181 glutathione peroxidase 795 caspase-1 679 luciferase 577 focal adhesion kinase 573 alanine aminotransferase 572 protein kinase C 555 caspase-7 539 caspase-7 538 proteasome 521 MEK 504 aspartate aminotransferase 497 peroxidase 422 phosphatidylinositol 3-kinase 419 GSK 378 AMP-activated protein kinase 347 cdc2 330 caspase-2 292 caspase-2 289 NADPH oxidase 272 creatine kinase 260 NADPH oxidase 252 ATPase 242 caspase-6 241 caspase-6 235 phosphoinositide 3-kinase 233 TdT 227 AMPK 220 glutathione S-transferase 214 AMPK 205 tyrosine hydroxylase 191 NO synthase 182 calcineurin 181 alkaline phosphatase 177 glutathione reductase 177 AST 172 complex I 170 acetylcholinesterase 164 cathepsin B 160 MPP 158 P-glycoprotein 153 MMP 150 topoisomerase 147 granzyme B 141 topoisomerase 136 heme oxygenase 127 MAP 119 ACS 117 reverse transcriptase 115 collagenase 115 IKK 110 NQO1 105 cathepsin D 102 caspase-4 98 NOS 96 endonuclease 95 thrombin 87 caspase-4 85 m-calpain 77 phospholipase C 74 trypsin 74 phosphodiesterase 73 phospholipase A2 71 mu-calpain 70 succinate dehydrogenase 70 Omi/HtrA2 67 DNase 66 xanthine oxidase 66 RNA polymerase 62 caspase-10 60 caspase-10 59 more...

Compound DNA 8418 oxygen 6343 Dec 3253 MTT 2915 TNF 2033 glucose 1729 GSH 1639 GSH 1639 dUTP 1594 calcium 1382 water 1308 nitric oxide 1177 MDA 1167 iodine 1126 cysteine 1125 ATP 1109 hydrogen 930 bromide 870 ADP-ribose 804 Asp 792 Clin 763 sodium 760 N-acetylcysteine 634 glutamate 574 H2O2 573 ethanol 535 ADP 489 serine 487 nitrogen 461 alanine 460 creatinine 445 tyrosine 438 ADP 424 ADP 423 urea 415 DDP 381 zinc 362 phosphate 350 iron 334 MEK 308 Curcumin 303 Hoechst 33342 298 acetate 296 arginine 294 galactose 285 acridine 276 threonine 261 Cyt 258 Adriamycin 250 ADR 250 Neuronal 248 cadmium 227 retinoic acid 225 cAMP 222 CAT 219 CAT 219 CAT 219 potassium 209 copper 207 Resveratrol 197 selenium 193 aldehyde 191 sulfate 191 Cytochrome c 190 lysine 188 boron 186 NH2 183 NAD 183 aldehyde 183 diacetate 176 Panam 172 THP 169 THP 169 8-OHdG 163 MTS 162 fluorine 159 MPP 158 MPP 158 leucine 154 NAD 152 more...

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