Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P42574 (
caspase-3
)
45,978
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
caspase-3
45978
Bcl-2
9955
caspase-9
5818
cytochrome c
5073
p53
4298
Mol
4112
caspase-8
3908
PARP
3807
Sep
2935
annexin V
2173
TNF
2033
p38
1975
Fas
1899
tumor necrosis factor
1785
superoxide dismutase
1726
GSH
1600
JNK
1447
p21
1437
ROS
1415
PI3K
1292
MAPK
1291
poly(ADP-ribose) polymerase
1285
endoplasmic reticulum
1284
AKT
1253
catalase
1245
cytokine
1159
lactate dehydrogenase
1146
ERK
1138
ATP
1109
ERK1
1103
cytochrome
1068
IL-6
1028
bcl-2
962
mTOR
912
inducible nitric oxide synthase
831
cyclin D1
831
Bid
810
survivin
797
glutathione peroxidase
785
poly (ADP-ribose) polymerase
777
more...
Disease
cancer
9401
tumor
5993
ischemia
2002
GSH
1601
breast cancer
1495
tumor growth
1455
leukemia
1424
carcinoma
1298
hepatocellular carcinoma
1273
Alzheimer's disease
1116
MCF
1016
diabetes
973
B-cell lymphoma
968
neuroblastoma
862
colon cancer
842
lung cancer
841
prostate cancer
753
Parkinson's disease
741
stroke
727
cerebral ischemia
686
adenocarcinoma
668
melanoma
643
colorectal cancer
597
carcinogenesis
590
tumorigenesis
555
glioma
540
gastric cancer
482
lymphoma
474
ovarian cancer
444
squamous cell carcinoma
432
osteosarcoma
393
cervical cancer
381
non-small cell lung cancer
367
glioblastoma
365
myocardial ischemia
345
liver cancer
325
pancreatic cancer
318
sepsis
315
multiple myeloma
309
hyperglycemia
306
more...
Symptom
collapse
307
seizures
201
starvation
190
functional recovery
169
anesthesia
148
pain
142
hypothermia
99
hyperoxia
83
diarrhea
72
respiratory distress
48
weakness
39
memory loss
36
thinning
33
ataxia
28
skin damage
25
cachexia
22
exhaustion
20
tremor
20
fatigue
18
acute stress
17
bradykinesia
17
acidity
13
vomiting
12
neurological disability
11
analgesia
10
HSA
10
dry eye
10
low back pain
9
overweight
9
Anoxia
9
headache
9
angina
9
incoordination
8
abdominal pain
8
hypercapnia
8
erythema
8
nausea
8
Neuropathic pain
7
cough
7
insomnia
6
more...
Drug
ROS
1415
Monit
186
ascorbate
156
MAP
153
vitamin E
142
lysine
137
Dermatol
130
IL-2
122
IFN-gamma
119
Cardiovasc
113
Ethanol
110
Arsenic trioxide
95
Glutathione
75
CSF
74
p75
74
AMC
73
Taxol
67
caffeine
64
TTC
63
CTX
56
Indomethacin
55
Bortezomib
54
ICI
54
Simvastatin
49
MRC
49
ZnO
48
Sorafenib
46
NADH
46
Heme
44
Glycyrrhiza
43
EE2
43
Propofol
42
Fluorescein
42
Etoposide
42
Imatinib
41
CED
40
TAT
40
Angiotensin II
39
ADR
38
Adriamycin
38
more...
Enzyme
caspase-3
35429
caspase-9
4758
mitogen-activated protein kinase
4383
PARP
4192
caspase-8
3145
superoxide dismutase
2288
ERK
1605
catalase
1443
protein kinase
1371
lactate dehydrogenase
1181
glutathione peroxidase
795
caspase-1
679
luciferase
577
focal adhesion kinase
573
alanine aminotransferase
572
protein kinase C
555
caspase-7
539
caspase-7
538
proteasome
521
MEK
504
aspartate aminotransferase
497
peroxidase
422
phosphatidylinositol 3-kinase
419
GSK
378
AMP-activated protein kinase
347
cdc2
330
caspase-2
292
caspase-2
289
NADPH oxidase
272
creatine kinase
260
NADPH oxidase
252
ATPase
242
caspase-6
241
caspase-6
235
phosphoinositide 3-kinase
233
TdT
227
AMPK
220
glutathione S-transferase
214
AMPK
205
tyrosine hydroxylase
191
more...
Compound
DNA
8418
oxygen
6343
Dec
3253
MTT
2915
TNF
2033
glucose
1729
GSH
1639
GSH
1639
dUTP
1594
calcium
1382
water
1308
nitric oxide
1177
MDA
1167
iodine
1126
cysteine
1125
ATP
1109
hydrogen
930
bromide
870
ADP-ribose
804
Asp
792
Clin
763
sodium
760
N-acetylcysteine
634
glutamate
574
H2O2
573
ethanol
535
ADP
489
serine
487
nitrogen
461
alanine
460
creatinine
445
tyrosine
438
ADP
424
ADP
423
urea
415
DDP
381
zinc
362
phosphate
350
iron
334
MEK
308
more...