Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42574 (caspase-3)
45,978 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
caspase-3 45978
Bcl-2 9955
caspase-9 5818
cytochrome c 5073
p53 4298
Mol 4112
caspase-8 3908
PARP 3807
Sep 2935
annexin V 2173
TNF 2033
p38 1975
Fas 1899
tumor necrosis factor 1785
superoxide dismutase 1726
GSH 1600
JNK 1447
p21 1437
ROS 1415
PI3K 1292
MAPK 1291
poly(ADP-ribose) polymerase 1285
endoplasmic reticulum 1284
AKT 1253
catalase 1245
cytokine 1159
lactate dehydrogenase 1146
ERK 1138
ATP 1109
ERK1 1103
cytochrome 1068
IL-6 1028
bcl-2 962
mTOR 912
inducible nitric oxide synthase 831
cyclin D1 831
Bid 810
survivin 797
glutathione peroxidase 785
poly (ADP-ribose) polymerase 777
more...
Disease
cancer 9401
tumor 5993
ischemia 2002
GSH 1601
breast cancer 1495
tumor growth 1455
leukemia 1424
carcinoma 1298
hepatocellular carcinoma 1273
Alzheimer's disease 1116
MCF 1016
diabetes 973
B-cell lymphoma 968
neuroblastoma 862
colon cancer 842
lung cancer 841
prostate cancer 753
Parkinson's disease 741
stroke 727
cerebral ischemia 686
adenocarcinoma 668
melanoma 643
colorectal cancer 597
carcinogenesis 590
tumorigenesis 555
glioma 540
gastric cancer 482
lymphoma 474
ovarian cancer 444
squamous cell carcinoma 432
osteosarcoma 393
cervical cancer 381
non-small cell lung cancer 367
glioblastoma 365
myocardial ischemia 345
liver cancer 325
pancreatic cancer 318
sepsis 315
multiple myeloma 309
hyperglycemia 306
more...
Symptom
collapse 307
seizures 201
starvation 190
functional recovery 169
anesthesia 148
pain 142
hypothermia 99
hyperoxia 83
diarrhea 72
respiratory distress 48
weakness 39
memory loss 36
thinning 33
ataxia 28
skin damage 25
cachexia 22
exhaustion 20
tremor 20
fatigue 18
acute stress 17
bradykinesia 17
acidity 13
vomiting 12
neurological disability 11
analgesia 10
HSA 10
dry eye 10
low back pain 9
overweight 9
Anoxia 9
headache 9
angina 9
incoordination 8
abdominal pain 8
hypercapnia 8
erythema 8
nausea 8
Neuropathic pain 7
cough 7
insomnia 6
more...
Drug
ROS 1415
Monit 186
ascorbate 156
MAP 153
vitamin E 142
lysine 137
Dermatol 130
IL-2 122
IFN-gamma 119
Cardiovasc 113
Ethanol 110
Arsenic trioxide 95
Glutathione 75
CSF 74
p75 74
AMC 73
Taxol 67
caffeine 64
TTC 63
CTX 56
Indomethacin 55
Bortezomib 54
ICI 54
Simvastatin 49
MRC 49
ZnO 48
Sorafenib 46
NADH 46
Heme 44
Glycyrrhiza 43
EE2 43
Propofol 42
Fluorescein 42
Etoposide 42
Imatinib 41
CED 40
TAT 40
Angiotensin II 39
ADR 38
Adriamycin 38
more...
Enzyme
caspase-3 35429
caspase-9 4758
mitogen-activated protein kinase 4383
PARP 4192
caspase-8 3145
superoxide dismutase 2288
ERK 1605
catalase 1443
protein kinase 1371
lactate dehydrogenase 1181
glutathione peroxidase 795
caspase-1 679
luciferase 577
focal adhesion kinase 573
alanine aminotransferase 572
protein kinase C 555
caspase-7 539
caspase-7 538
proteasome 521
MEK 504
aspartate aminotransferase 497
peroxidase 422
phosphatidylinositol 3-kinase 419
GSK 378
AMP-activated protein kinase 347
cdc2 330
caspase-2 292
caspase-2 289
NADPH oxidase 272
creatine kinase 260
NADPH oxidase 252
ATPase 242
caspase-6 241
caspase-6 235
phosphoinositide 3-kinase 233
TdT 227
AMPK 220
glutathione S-transferase 214
AMPK 205
tyrosine hydroxylase 191
more...
Compound
DNA 8418
oxygen 6343
Dec 3253
MTT 2915
TNF 2033
glucose 1729
GSH 1639
GSH 1639
dUTP 1594
calcium 1382
water 1308
nitric oxide 1177
MDA 1167
iodine 1126
cysteine 1125
ATP 1109
hydrogen 930
bromide 870
ADP-ribose 804
Asp 792
Clin 763
sodium 760
N-acetylcysteine 634
glutamate 574
H2O2 573
ethanol 535
ADP 489
serine 487
nitrogen 461
alanine 460
creatinine 445
tyrosine 438
ADP 424
ADP 423
urea 415
DDP 381
zinc 362
phosphate 350
iron 334
MEK 308
more...