Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42345 (mTOR)
 26,049 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
laminin, alpha 4 10.3
GCST 10.3
TBC1 domain family member 7 10.3
DHX57 10.3
mTOR 10.3
FAM178A 10.3
KIAA0406 10.3
WD repeat domain 24 10.3
SNF related kinase 10.3
CRHSP24 10.3
KLHDC3 10.3
Tuberous sclerosis 1 10.3
ZNF426 10.3
PCDHGC3 10.3
KDEL (Lys-Asp-Glu-Leu) containing 2 10.3
phosphodiesterase 3B, cGMP-inhibited 10.3
TNFSF13 protein 10.3
anaphase-promoting complex subunit 7 10.3
ATP5A protein 10.3
DNA replication complex GINS protein PSF2 10.3
Ras-related GTP binding B 10.3
ZNF605 10.3
partner of NOB1 10.3
six-transmembrane epithelial antigen of prostate 2 10.3
Basic leucine zipper and W2 domains 2 10.3
CRISPLD1 10.3
PCDHGB4 10.3
SH2B3 protein 10.3
Unkempt-like 10.3
ZSCAN29 10.3
Aryl-hydrocarbon receptor interacting protein 10.3
raptor protein 9.9
Tumor suppressor candidate 4 9.7
Rheb2 9.7
EIF4EBP2 9.6
4EBP1 9.6
Protor-1 9.5
mitogen-activated protein kinase kinase kinase kinase 3 9.5
P70S6K 9.5
S6K2 9.5
Raptor 9.5
S6K1 9.5
ribosomal protein S6 kinase 1 9.4
Rheb 9.4
RICTOR 9.4
4E-BP1 9.3
Ras homolog enriched in brain 9.3
thyroid adenoma associated 9.3
Protor-2 9.3
TSC1 protein 9.3
MAPK1IP1L 9.3
asparagine-linked glycosylation 13 homolog 9.3
serum amyloid A-like 1 9.3
TBC1D7 protein 9.3
ARL6IP2 9.3
NEDD4L variant 9.3
ANG-5 9.3
plakophilin 4 9.3
Tuftelin 1 9.3
M6PR protein 9.3
GRAMD1C 9.3
Alpha-2,8-sialyltransferase 9.3
UBX domain protein 11 9.3
EVI5L 9.3
ACTR6 9.3
ARMCX4 9.3
ANGPT3 9.3
transmembrane protein 93 9.3
Poly (ADP-ribose) glycohydrolase 9.3
Regulatory factor X 7 9.3
Exophilin-5 9.3
phosphoinositide-3-kinase, catalytic, delta polypeptide 9.3
regulator of G protein signaling 12 9.3
Eukaryotic translation initiation factor 5B 9.3
Adenylyl cyclase-associated protein 9.3
C17orf75 9.3
RNH1 protein 9.3
p44.5 9.3
Starch-binding domain-containing protein 1 9.3
P55PIK 9.3
more...
Disease
Idiopathic (IPAH) 10.3
Insulin-resistant diabetes 8.7
Multiple Lentigines 8.3
Amino acid deficiency 8.3
Glucagon resistance 8.3
Pancreatic mass 8.3
Multifocal micronodular pneumocyte hyperplasia 7.9
Cardiac rhabdomyoma 7.9
dual addiction 7.9
tuberous sclerosis 7.7
pre-T LBL 7.7
Subependymal giant cell astrocytoma 7.6
adult pilocytic astrocytoma 7.4
T Cell Leukemia 7.4
pulmonary vascular disorder 7.4
Ischemic cerebral infarction 7.4
Myxoid chondrosarcoma 7.4
SHORT syndrome 7.3
recurrent Ewing's sarcoma 7.3
type C thymoma 7.3
relapsed small lymphocytic lymphoma 7.1
phakoma 7.1
Papillary Thyroid Carcinoma 7.1
Unilateral condylar hyperplasia 7.1
Leishmania tropica infection 7.1
Malignant Peripheral Nerve Sheath Tumor 6.9
DIPNECH 6.8
Multiple cancer 6.8
High grade prostatic intraepithelial neoplasia 6.8
metastatic renal cell carcinoma 6.7
BHD 6.7
Hidradenocarcinoma 6.7
PEComa 6.6
BHD 6.6
Hyper IgM syndrome 6.6
Egg drop syndrome 6.6
ATP synthase deficiency 6.6
skin pigmentation disorder 6.6
Cortical dysplasia 6.5
lymphangioleiomyomatosis 6.5
Centrilobular emphysema 6.4
Autosomal recessive hypophosphatemic rickets 6.4
Metastatic squamous cell carcinoma 6.4
Diffuse astrocytoma 6.3
Pulmonary lymphangioleiomyomatosis 6.3
EBSS 6.3
Small cell osteosarcoma 6.3
grade II meningioma 6.3
Athlete's heart 6.3
Invasive bladder cancer 6.2
Facial angiofibromas 6.1
Fanconi-like syndrome 6.1
Brailsford 6.1
metastatic follicular thyroid cancer 6.0
Kaposiform hemangioendothelioma 6.0
Granular corneal dystrophy 6.0
CNS germinoma 6.0
Demyelinating disorders 5.9
Myelokathexis 5.9
Cystic kidney disease 5.9
unable to stop smoking 5.9
Endometrial Carcinoma 5.9
recurrent endometrial cancer 5.9
Autosomal dominant polycystic kidney disease 5.9
Ph-positive acute lymphoblastic leukemia 5.9
recurrent neuroblastoma 5.9
LKE 5.9
metastatic parathyroid carcinoma 5.8
Hepatitis B reactivation 5.8
Polycystic liver disease 5.8
IBMPFD 5.8
recurrent osteosarcoma 5.8
HIVAN 5.7
Hypopharynx 5.7
bone marrow cancer 5.7
ALS8 5.7
Congenital myotonic dystrophy 5.7
angiomyolipoma 5.6
Sticker 5.6
WM1 5.6
more...
Symptom
Convulsive seizure 6.3
difficulty with urination 5.5
Peripheral neuropathic pain 5.3
localized abdominal pain 5.1
finger pain 5.0
Scratch 4.4
starvation 4.4
brittle nails 4.2
delayed language development 3.8
Excitable 3.8
peri-menopausal 3.8
elevated mood 3.5
nerve pain 3.5
cachexia 3.5
facial droop 3.3
Muscle soreness 3.1
Neuropathic pain 2.8
pachyonychia 2.7
functional recovery 2.6
neurological disability 2.4
motor symptom 2.4
exhaustion 2.2
male subfertility 2.2
memory loss 2.1
seizures 1.9
despair 1.9
loin pain 1.9
asthenia 1.9
leg edema 1.9
bladder pain 1.6
hypotonia 1.4
loss of balance 1.4
Decreased activity 1.2
swollen joints 1.2
Anoxia 1.1
personality change 1.1
urinary frequency 1.1
anorexia 1.1
pelvic pain 1.1
splenomegaly 1.1
decreased appetite 1.1
incoordination 1.0
fatigue 1.0
hyperoxia 0.9
right upper quadrant pain 0.8
ataxia 0.8
hepatomegaly 0.8
polydipsia 0.7
collapse 0.7
skin damage 0.7
intestinal bleeding 0.6
menopausal symptoms 0.6
rigors 0.6
general problem 0.5
diarrhea 0.5
dry eye 0.5
flushing 0.4
dysesthesia 0.4
overweight 0.3
hoarseness 0.3
acute pain 0.3
dry skin 0.3
arthralgia 0.3
blurred vision 0.2
bone pain 0.2
joint stiffness 0.2
hypothermia 0.2
weakness 0.1
abnormal gait 0.1
hunger 0.1
exertional dyspnea 0.1
night sweats 0.0
hot flushes -0.0
myalgia -0.1
tonic-clonic seizure -0.1
acidity -0.2
nausea -0.2
hepatosplenomegaly -0.3
polyuria -0.3
hemoptysis -0.3
more...
Drug
Benproperine phosphate 10.3
Torisel 9.7
Everolimus 9.3
Tandutinib 8.4
Rapamune 8.1
NVP 8.0
N-Formylmethionine 7.9
3-Methyladenine 7.6
Atractylodes rhizome 7.1
Lonafarnib 7.0
Balanol 6.9
Nexavar 6.8
Aromasin 6.8
Loxoribine 6.7
Emcyt 6.6
Fidarestat 6.4
Fidarestat 6.4
Longgu 6.4
Sunitinib malate 6.4
Belatacept 6.4
Platonin 6.3
Acadesine 6.3
Vandetanib 6.2
Aescin 6.2
Safingol 6.1
Sorafenib 6.1
Tykerb 6.1
Metreleptin 5.9
Motesanib 5.9
Purvalanol 5.7
Epothilone B 5.7
Arachidonic Acid 5.6
Zotarolimus 5.6
Pertuzumab 5.5
Provenge 5.4
Romidepsin 5.4
Norleucine 5.4
Adenosine Monophosphate 5.3
Tipifarnib 5.1
Fulvestrant 5.0
Stelazine 4.9
Pemetrexed 4.9
Thioridazine 4.9
Cetuximab 4.9
Emodin 4.8
fluphenazine dihydrochloride 4.8
Compound 19 4.8
Cilastatin 4.8
Axitinib 4.8
Erlotinib 4.8
Vatalanib 4.8
Pirarubicin 4.7
Bosutinib 4.7
Gefitinib 4.7
Benzofuran 4.7
Artesunate 4.6
Epalrestat 4.6
Myricetin 4.6
Bevacizumab 4.6
Emodin 4.5
Herceptin 4.5
Parkin 4.5
Parkin 4.5
Tarceva 4.5
Panitumumab 4.5
Liraglutide 4.5
Dasatinib 4.5
Ara-A 4.4
Imatinib 4.4
Alarin 4.4
ROS 4.4
Vorinostat 4.4
Ontak 4.3
Ontak 4.3
RFP 4.3
Nipradilol 4.3
Midostaurin 4.3
Asparaginase 4.3
Rhubarb 4.2
Arsenic trioxide 4.2
more...
Enzyme
phosphatidylinositol-3-phosphatase 8.7
AMPK 7.9
eEF2 kinase 7.7
AMP-activated protein kinase 7.5
phosphatidylinositol-4,5-bisphosphate 3-kinase 7.3
phosphoinositide 3-kinase 7.2
AMP-activated kinase 7.1
EC 6.1.1.1 7.1
TOR 7.1
AMPK 7.0
PDK1 6.8
phosphatidylinositol 3-kinase 6.8
inositol 3-kinase 6.8
inositol polyphosphate 4-phosphatase 6.7
STK11 6.3
ecdysone oxidase 6.0
MEK 5.9
GK2 5.8
HK2 5.8
STK2 5.7
acylglycerol kinase 5.6
GSK 5.5
branched-chain aminotransferase 5.4
PARP 5.1
protein phosphatase 2A 5.1
mitogen-activated protein kinase 5.1
Ins(1,4,5)P3 3-kinase 5.0
leucyl-tRNA synthetase 5.0
isochorismatase 5.0
farnesyltransferase 5.0
ERK 5.0
calcineurin 5.0
thiaminase 4.9
glycyl-tRNA synthetase 4.9
pyruvate dehydrogenase phosphatase 4.8
acetyl-CoA carboxylase 4.8
asparagine synthetase 4.7
ribulose 5-phosphate 3-epimerase 4.7
protein kinase 4.6
farnesyltransferase 4.6
caspase-3 4.5
focal adhesion kinase 4.5
caspase-7 4.4
phosphatidylinositol 4-kinase 4.4
polyphosphatase 4.4
caspase-7 4.4
enzyme X 4.4
succinic semialdehyde dehydrogenase 4.4
CTP synthase 4.3
phospholipase D 4.3
caspase-9 4.3
glutaminase 4.3
Tpt1 4.3
branched-chain alpha-keto acid dehydrogenase 4.2
D-dopachrome tautomerase 4.2
IKK 4.2
seryl-tRNA synthetase 4.1
10-formyltetrahydrofolate dehydrogenase 4.1
thiaminase 4.1
proteasome 4.1
phosphatidate phosphatase 4.1
dihydroorotase 4.1
cdc2 4.1
malonyl-CoA decarboxylase 4.1
cathepsin X 4.0
nicotinamide phosphoribosyltransferase 4.0
STK 4.0
ALDH 4.0
MPP 4.0
IMP dehydrogenase 4.0
protein L-isoaspartyl methyltransferase 4.0
inositol phosphatase 3.9
fatty acid elongase 3.8
Omi/HtrA2 3.8
mu-calpain 3.8
proline oxidase 3.7
methylcrotonyl-CoA carboxylase 3.7
cathepsin K 3.7
isopeptidase 3.7
diacylglycerol kinase 3.6
more...
Compound
12-Deoxyphorbol 13-palmitate 10.3
Chelerythrine hydrochloride 10.3
Postin 10.3
8-Aminoadenosine 10.3
8-Aminoadenosine 10.3
Temsirolimus 9.6
Gymnemic acid I 9.3
Rapamycin 8.7
C10H13N5O5 8.7
Oxyphenisatin 8.7
Scirpusin A 8.7
Dioxindole 8.7
Tuberin 8.6
Eburicoic acid 8.3
C8H8O3 8.3
6-methylquinoxaline 8.3
XCT 790 8.3
Auriculasin 8.3
Sinulariolide 8.1
TSC 8.0
C19H18O3 7.9
1-(4-chlorophenyl)ethanol 7.9
C19H18O3 7.9
Tephrosin 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
Mahanimbine 7.9
C19H18O3 7.9
C19H18O3 7.9
Pristimerin 7.8
Pristimerin 7.8
Pristimerin 7.8
Pristimerin 7.8
Gartanin 7.7
Xanthotoxol 7.7
C19H18O3 7.7
C19H18O3 7.7
3-Methyladenine 7.6
Guaiol 7.4
Sinensetin 7.4
Deltonin 7.4
C10H12O2 7.4
Virosecurinine 7.4
Cotylenin A 7.4
C19H18O3 7.4
Jervine 7.4
Sinularin 7.3
Diphyllin 7.3
Ginkgolide C 7.3
C19H18O3 7.3
Panaxatriol 7.3
Aloperine 7.1
[1,2,4]triazolo[1,5-a]pyridine 7.1
Veratramine 7.1
N-acetylleucine 7.1
N-acetylleucine 7.1
Coumarin 30 7.1
Girinimbine 7.1
HBPA 7.1
Raddeanin A 7.0
AICAR 7.0
5-bromo-2-hydroxybenzaldehyde 6.9
C19H18O3 6.9
Monotropein 6.8
Sulfamonomethoxine 6.8
N-acetylleucine 6.8
Apigetrin 6.8
imidazo[1,5-a]pyrazine 6.7
Chebulagic acid 6.7
Chebulagic acid 6.7
more...