Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42345 (mTOR)
26,049 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
mTOR 1.000
PI3K 0.039
AKT 0.032
S6K1 0.025
4E-BP1 0.022
TSC2 0.012
4EBP1 0.011
AMPK 0.010
TSC1 0.009
ribosomal protein S6 0.009
Raptor 0.007
LC3 0.007
Rheb 0.006
protein kinase B 0.005
raptor 0.004
p70 0.004
PTEN 0.004
phosphatidylinositol 3-kinase 0.004
p70 S6 kinase 0.004
P70S6K 0.004
phosphoinositide 3-kinase 0.003
p62 0.003
Beclin-1 0.003
AMP-activated protein kinase 0.003
eIF4E 0.003
ULK1 0.002
ribosomal protein S6 kinase 1 0.002
ERK 0.002
RICTOR 0.002
tuberin 0.002
MAPK 0.002
ribosomal S6 kinase 0.002
PIK3CA 0.002
REDD1 0.002
Ras homolog enriched in brain 0.002
MEK 0.002
LC3B 0.001
eukaryotic translation initiation factor 4E 0.001
TSC 0.001
phosphatase and tensin homolog 0.001
more...
Disease
tuberous sclerosis 0.006
cancer 0.002
tumor 0.002
tumor growth 0.001
tumorigenesis 0.001
metastatic renal cell carcinoma 0.001
renal cell carcinoma 0.001
breast cancer 0.000
lymphangioleiomyomatosis 0.000
hepatocellular carcinoma 0.000
tumor progression 0.000
glioblastoma 0.000
renal cancer 0.000
prostate cancer 0.000
Hippel 0.000
non-small cell lung cancer 0.000
carcinogenesis 0.000
glioma 0.000
lung cancer 0.000
polycystic kidney 0.000
MCF 0.000
colorectal cancer 0.000
ovarian cancer 0.000
obesity 0.000
angiomyolipoma 0.000
mantle cell lymphoma 0.000
Hepatocellular carcinoma 0.000
liver cancer 0.000
tumor angiogenesis 0.000
gastric cancer 0.000
PEComa 0.000
pancreatic cancer 0.000
Autosomal dominant polycystic kidney disease 0.000
liver cancer 0.000
diabetes 0.000
squamous cell carcinoma 0.000
colon cancer 0.000
carcinoma 0.000
metastatic breast cancer 0.000
Blocking 0.000
more...
Symptom
starvation 0.000
seizures 0.000
cachexia 0.000
functional recovery 0.000
Convulsive seizure 0.000
exhaustion 0.000
Scratch 0.000
difficulty with urination 0.000
fatigue 0.000
Peripheral neuropathic pain 0.000
localized abdominal pain 0.000
finger pain 0.000
diarrhea 0.000
pain 0.000
brittle nails 0.000
Neuropathic pain 0.000
memory loss 0.000
collapse 0.000
peri-menopausal 0.000
delayed language development 0.000
anorexia 0.000
Excitable 0.000
elevated mood 0.000
nerve pain 0.000
ataxia 0.000
hypotonia 0.000
splenomegaly 0.000
weakness 0.000
facial droop 0.000
asthenia 0.000
overweight 0.000
Muscle soreness 0.000
neurological disability 0.000
despair 0.000
pachyonychia 0.000
motor symptom 0.000
hypothermia 0.000
pelvic pain 0.000
hyperoxia 0.000
male subfertility 0.000
more...
Drug
Everolimus 0.007
NVP 0.002
ROS 0.000
Torisel 0.000
Sorafenib 0.000
3-Methyladenine 0.000
Rapamune 0.000
Benproperine phosphate 0.000
Nexavar 0.000
Tandutinib 0.000
Herceptin 0.000
Sunitinib malate 0.000
Imatinib 0.000
Parkin 0.000
Bevacizumab 0.000
Parkin 0.000
Belatacept 0.000
Lonafarnib 0.000
Cetuximab 0.000
Vandetanib 0.000
N-Formylmethionine 0.000
Gefitinib 0.000
Atractylodes rhizome 0.000
Erlotinib 0.000
Aromasin 0.000
IL-2 0.000
RFP 0.000
Bortezomib 0.000
MAP 0.000
Balanol 0.000
Arsenic trioxide 0.000
Emodin 0.000
Fidarestat 0.000
Fidarestat 0.000
Pemetrexed 0.000
Loxoribine 0.000
Fulvestrant 0.000
Tykerb 0.000
Acadesine 0.000
Pertuzumab 0.000
more...
Enzyme
AMP-activated protein kinase 0.011
AMPK 0.010
AMPK 0.005
phosphatidylinositol 3-kinase 0.004
phosphoinositide 3-kinase 0.003
mitogen-activated protein kinase 0.003
ERK 0.002
MEK 0.002
protein kinase 0.001
PDK1 0.001
TOR 0.001
focal adhesion kinase 0.001
caspase-3 0.000
PARP 0.000
calcineurin 0.000
GSK 0.000
eEF2 kinase 0.000
AMP-activated kinase 0.000
proteasome 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
protein phosphatase 2A 0.000
inositol 3-kinase 0.000
STK11 0.000
caspase-9 0.000
protein kinase C 0.000
luciferase 0.000
cdc2 0.000
acetyl-CoA carboxylase 0.000
HK2 0.000
IKK 0.000
phospholipase D 0.000
phosphatidylinositol-3-phosphatase 0.000
farnesyltransferase 0.000
farnesyltransferase 0.000
MAP 0.000
glutaminase 0.000
caspase-8 0.000
superoxide dismutase 0.000
inositol polyphosphate 4-phosphatase 0.000
complex I 0.000
more...
Compound
Rapamycin 0.016
Temsirolimus 0.003
MEK 0.002
TSC 0.001
Metformin 0.001
Metformin 0.001
AICAR 0.000
Tuberin 0.000
glucose 0.000
Leucine 0.000
MTT 0.000
threonine 0.000
AICAR 0.000
3-Methyladenine 0.000
oxygen 0.000
leucine 0.000
MDA 0.000
ATP 0.000
Phosphatidylinositol 0.000
serine 0.000
Insulin 0.000
TNF 0.000
tyrosine 0.000
DNA 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
LY 294002 0.000
glutamine 0.000
AMP 0.000
Wortmannin 0.000
methionine 0.000
FK506 0.000
Postin 0.000
Chelerythrine hydrochloride 0.000
12-Deoxyphorbol 13-palmitate 0.000
8-Aminoadenosine 0.000
8-Aminoadenosine 0.000
Dec 0.000
more...