Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42345 (mTOR)
 26,049 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
Unkempt-like 10.3
phosphodiesterase 3B, cGMP-inhibited 10.3
WD repeat domain 24 10.3
anaphase-promoting complex subunit 7 10.3
KDEL (Lys-Asp-Glu-Leu) containing 2 10.3
partner of NOB1 10.3
DNA replication complex GINS protein PSF2 10.3
TBC1 domain family member 7 10.3
mTOR 10.3
SNF related kinase 10.3
FAM178A 10.3
CRISPLD1 10.3
ZSCAN29 10.3
six-transmembrane epithelial antigen of prostate 2 10.3
KLHDC3 10.3
PCDHGB4 10.3
Basic leucine zipper and W2 domains 2 10.3
TNFSF13 protein 10.3
GCST 10.3
DHX57 10.3
SH2B3 protein 10.3
ZNF605 10.3
CRHSP24 10.3
KIAA0406 10.3
Ras-related GTP binding B 10.3
Aryl-hydrocarbon receptor interacting protein 10.3
laminin, alpha 4 10.3
Tuberous sclerosis 1 10.3
ZNF426 10.3
PCDHGC3 10.3
ATP5A protein 10.3
raptor protein 9.9
Rheb2 9.7
Tumor suppressor candidate 4 9.7
EIF4EBP2 9.6
4EBP1 9.6
mitogen-activated protein kinase kinase kinase kinase 3 9.5
Protor-1 9.5
P70S6K 9.5
S6K2 9.5
more...
Disease
Idiopathic (IPAH) 10.3
Insulin-resistant diabetes 8.7
Multiple Lentigines 8.3
Pancreatic mass 8.3
Glucagon resistance 8.3
Amino acid deficiency 8.3
Cardiac rhabdomyoma 7.9
Multifocal micronodular pneumocyte hyperplasia 7.9
dual addiction 7.9
tuberous sclerosis 7.7
pre-T LBL 7.7
Subependymal giant cell astrocytoma 7.6
T Cell Leukemia 7.4
adult pilocytic astrocytoma 7.4
Ischemic cerebral infarction 7.4
Myxoid chondrosarcoma 7.4
pulmonary vascular disorder 7.4
SHORT syndrome 7.3
recurrent Ewing's sarcoma 7.3
type C thymoma 7.3
relapsed small lymphocytic lymphoma 7.1
Papillary Thyroid Carcinoma 7.1
Leishmania tropica infection 7.1
phakoma 7.1
Unilateral condylar hyperplasia 7.1
Malignant Peripheral Nerve Sheath Tumor 6.9
DIPNECH 6.8
High grade prostatic intraepithelial neoplasia 6.8
Multiple cancer 6.8
metastatic renal cell carcinoma 6.7
BHD 6.7
Hidradenocarcinoma 6.7
PEComa 6.6
BHD 6.6
skin pigmentation disorder 6.6
Egg drop syndrome 6.6
Hyper IgM syndrome 6.6
ATP synthase deficiency 6.6
Cortical dysplasia 6.5
lymphangioleiomyomatosis 6.5
more...
Symptom
Convulsive seizure 6.3
difficulty with urination 5.5
Peripheral neuropathic pain 5.3
localized abdominal pain 5.1
finger pain 5.0
Scratch 4.4
starvation 4.4
brittle nails 4.2
delayed language development 3.8
Excitable 3.8
peri-menopausal 3.8
elevated mood 3.5
nerve pain 3.5
cachexia 3.5
facial droop 3.3
Muscle soreness 3.1
Neuropathic pain 2.8
pachyonychia 2.7
functional recovery 2.6
neurological disability 2.4
motor symptom 2.4
exhaustion 2.2
male subfertility 2.2
memory loss 2.1
seizures 1.9
despair 1.9
loin pain 1.9
asthenia 1.9
leg edema 1.9
bladder pain 1.6
hypotonia 1.4
loss of balance 1.4
Decreased activity 1.2
swollen joints 1.2
Anoxia 1.1
personality change 1.1
urinary frequency 1.1
anorexia 1.1
pelvic pain 1.1
splenomegaly 1.1
more...
Drug
Benproperine phosphate 10.3
Torisel 9.7
Everolimus 9.3
Tandutinib 8.4
Rapamune 8.1
NVP 8.0
N-Formylmethionine 7.9
3-Methyladenine 7.6
Atractylodes rhizome 7.1
Lonafarnib 7.0
Balanol 6.9
Nexavar 6.8
Aromasin 6.8
Loxoribine 6.7
Emcyt 6.6
Longgu 6.4
Fidarestat 6.4
Fidarestat 6.4
Sunitinib malate 6.4
Belatacept 6.4
Platonin 6.3
Acadesine 6.3
Vandetanib 6.2
Aescin 6.2
Safingol 6.1
Sorafenib 6.1
Tykerb 6.1
Motesanib 5.9
Metreleptin 5.9
Purvalanol 5.7
Epothilone B 5.7
Arachidonic Acid 5.6
Zotarolimus 5.6
Pertuzumab 5.5
Provenge 5.4
Romidepsin 5.4
Norleucine 5.4
Adenosine Monophosphate 5.3
Tipifarnib 5.1
Fulvestrant 5.0
more...
Enzyme
phosphatidylinositol-3-phosphatase 8.7
AMPK 7.9
eEF2 kinase 7.7
AMP-activated protein kinase 7.5
phosphatidylinositol-4,5-bisphosphate 3-kinase 7.3
phosphoinositide 3-kinase 7.2
AMP-activated kinase 7.1
EC 6.1.1.1 7.1
TOR 7.1
AMPK 7.0
PDK1 6.8
phosphatidylinositol 3-kinase 6.8
inositol 3-kinase 6.8
inositol polyphosphate 4-phosphatase 6.7
STK11 6.3
ecdysone oxidase 6.0
MEK 5.9
GK2 5.8
HK2 5.8
STK2 5.7
acylglycerol kinase 5.6
GSK 5.5
branched-chain aminotransferase 5.4
PARP 5.1
protein phosphatase 2A 5.1
mitogen-activated protein kinase 5.1
Ins(1,4,5)P3 3-kinase 5.0
leucyl-tRNA synthetase 5.0
isochorismatase 5.0
farnesyltransferase 5.0
ERK 5.0
calcineurin 5.0
thiaminase 4.9
glycyl-tRNA synthetase 4.9
pyruvate dehydrogenase phosphatase 4.8
acetyl-CoA carboxylase 4.8
asparagine synthetase 4.7
ribulose 5-phosphate 3-epimerase 4.7
protein kinase 4.6
farnesyltransferase 4.6
more...
Compound
8-Aminoadenosine 10.3
8-Aminoadenosine 10.3
Postin 10.3
12-Deoxyphorbol 13-palmitate 10.3
Chelerythrine hydrochloride 10.3
Temsirolimus 9.6
Gymnemic acid I 9.3
Rapamycin 8.7
Dioxindole 8.7
Oxyphenisatin 8.7
Scirpusin A 8.7
C10H13N5O5 8.7
Tuberin 8.6
6-methylquinoxaline 8.3
Eburicoic acid 8.3
C8H8O3 8.3
XCT 790 8.3
Auriculasin 8.3
Sinulariolide 8.1
TSC 8.0
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
Tephrosin 7.9
C19H18O3 7.9
C19H18O3 7.9
1-(4-chlorophenyl)ethanol 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
Mahanimbine 7.9
C19H18O3 7.9
C19H18O3 7.9
C19H18O3 7.9
Pristimerin 7.8
more...