Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P42345 (mTOR)
26,049 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein mTOR 26049 PI3K 4856 AKT 4378 Mol 2655 insulin 1789 Sep 1559 AMPK 1249 MAPK 1215 ERK 1170 S6K1 1123 p53 1099 LC3 1078 4E-BP1 1076 phosphatidylinositol 3-kinase 1035 PTEN 945 protein kinase B 930 caspase-3 912 AMP-activated protein kinase 784 Bcl-2 739 phosphoinositide 3-kinase 730 vascular endothelial growth factor 728 MEK 719 TSC2 707 tyrosine kinase 692 ATP 679 p62 666 cytokine 641 ribosomal protein S6 626 ERK1 607 epidermal growth factor receptor 565 TSC1 561 VEGF 512 p38 501 p70 495 EGFR 491 endoplasmic reticulum 464 Beclin-1 456 4EBP1 448 eIF4E 429 cyclin D1 413 more...

Disease cancer 7700 tumor 5265 breast cancer 1380 tumor growth 1317 tumorigenesis 1078 tuberous sclerosis 954 diabetes 777 hepatocellular carcinoma 735 renal cell carcinoma 636 obesity 615 carcinoma 554 lung cancer 532 tumor progression 531 carcinogenesis 515 prostate cancer 506 metastases 437 leukemia 417 colorectal cancer 411 Alzheimer's disease 384 melanoma 358 adenocarcinoma 357 glioma 350 glioblastoma 336 type 2 diabetes 326 non-small cell lung cancer 310 epilepsy 308 MCF 308 squamous cell carcinoma 306 gastric cancer 304 ovarian cancer 297 ischemia 291 lymphoma 255 colon cancer 246 acute myeloid leukemia 236 Parkinson's disease 229 metastatic renal cell carcinoma 225 pancreatic cancer 225 hypertension 212 multiple myeloma 201 depression 199 more...

Symptom starvation 419 seizures 253 pain 141 fatigue 83 functional recovery 68 diarrhea 66 exhaustion 52 cachexia 52 collapse 38 weakness 34 anesthesia 31 overweight 27 anorexia 24 ataxia 23 splenomegaly 17 nausea 17 dyspnea 16 hypothermia 16 cough 15 memory loss 13 hypotonia 13 acidity 11 vomiting 10 respiratory distress 10 headache 9 hepatomegaly 8 hyperoxia 8 Neuropathic pain 8 asthenia 8 pelvic pain 7 analgesia 7 flushing 7 Scratch 7 arthralgia 7 abdominal pain 7 hunger 5 myalgia 5 erythema 5 discomfort 5 discomfort 5 more...

Drug Everolimus 350 ROS 327 NVP 199 Dermatol 114 IL-2 103 lysine 93 Sorafenib 83 Monit 74 MAP 73 Cardiovasc 52 Herceptin 43 Imatinib 43 Parkin 35 Parkin 35 Bevacizumab 34 CSF 30 3-Methyladenine 26 Gefitinib 25 NADH 24 Cetuximab 23 Ethanol 23 caffeine 22 Bortezomib 22 Glucagon 22 ENT 20 RFP 20 DM1 19 Arsenic trioxide 19 Erlotinib 17 lactose 17 Dial 17 Tacrolimus 17 GEO 16 ABC 16 Gleevec 16 IFN-gamma 15 CoCl2 14 CoCl2 14 Rituximab 14 EE2 13 more...

Enzyme mitogen-activated protein kinase 2647 ERK 2431 AMP-activated protein kinase 1962 protein kinase 1578 AMPK 1266 AMPK 1249 phosphatidylinositol 3-kinase 1035 MEK 880 focal adhesion kinase 788 phosphoinositide 3-kinase 730 caspase-3 641 calcineurin 433 proteasome 408 PARP 394 protein kinase C 315 luciferase 264 GSK 260 PDK1 210 superoxide dismutase 169 TOR 161 ATPase 136 caspase-9 123 cdc2 115 lactate dehydrogenase 107 catalase 105 protein phosphatase 2A 84 IKK 75 alanine aminotransferase 73 aspartate aminotransferase 68 MAP 64 acetyl-CoA carboxylase 64 phospholipase D 62 ACS 59 complex I 59 caspase-8 57 RNA polymerase 56 P-glycoprotein 56 AMP-activated kinase 52 alkaline phosphatase 51 NADPH oxidase 42 more...

Compound Dec 1663 glucose 1567 DNA 1420 oxygen 1247 Rapamycin 1170 Clin 891 MEK 717 ATP 679 threonine 515 leucine 500 tyrosine 493 MTT 456 serine 444 TNF 402 calcium 365 MDA 305 methionine 298 Insulin 285 AMP 282 water 279 Metformin 239 Metformin 239 glutamine 230 phosphate 223 glutamate 187 sodium 186 arginine 167 cAMP 161 cysteine 159 nitric oxide 154 hydrogen 135 lysine 133 TSC 131 Leucine 124 nitrogen 119 urea 117 N-acetylcysteine 115 Temsirolimus 106 alanine 105 acetate 103 more...

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