Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P42345 (
mTOR
)
26,049
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mTOR
26049
PI3K
4856
AKT
4378
Mol
2655
insulin
1789
Sep
1559
AMPK
1249
MAPK
1215
ERK
1170
S6K1
1123
p53
1099
LC3
1078
4E-BP1
1076
phosphatidylinositol 3-kinase
1035
PTEN
945
protein kinase B
930
caspase-3
912
AMP-activated protein kinase
784
Bcl-2
739
phosphoinositide 3-kinase
730
more...
Disease
cancer
7700
tumor
5265
breast cancer
1380
tumor growth
1317
tumorigenesis
1078
tuberous sclerosis
954
diabetes
777
hepatocellular carcinoma
735
renal cell carcinoma
636
obesity
615
carcinoma
554
lung cancer
532
tumor progression
531
carcinogenesis
515
prostate cancer
506
metastases
437
leukemia
417
colorectal cancer
411
Alzheimer's disease
384
melanoma
358
more...
Symptom
starvation
419
seizures
253
pain
141
fatigue
83
functional recovery
68
diarrhea
66
cachexia
52
exhaustion
52
collapse
38
weakness
34
anesthesia
31
overweight
27
anorexia
24
ataxia
23
splenomegaly
17
nausea
17
hypothermia
16
dyspnea
16
cough
15
memory loss
13
more...
Drug
Everolimus
350
ROS
327
NVP
199
Dermatol
114
IL-2
103
lysine
93
Sorafenib
83
Monit
74
MAP
73
Cardiovasc
52
Imatinib
43
Herceptin
43
Parkin
35
Parkin
35
Bevacizumab
34
CSF
30
3-Methyladenine
26
Gefitinib
25
NADH
24
Cetuximab
23
more...
Enzyme
mitogen-activated protein kinase
2647
ERK
2431
AMP-activated protein kinase
1962
protein kinase
1578
AMPK
1266
AMPK
1249
phosphatidylinositol 3-kinase
1035
MEK
880
focal adhesion kinase
788
phosphoinositide 3-kinase
730
caspase-3
641
calcineurin
433
proteasome
408
PARP
394
protein kinase C
315
luciferase
264
GSK
260
PDK1
210
superoxide dismutase
169
TOR
161
more...
Compound
Dec
1663
glucose
1567
DNA
1420
oxygen
1247
Rapamycin
1170
Clin
891
MEK
717
ATP
679
threonine
515
leucine
500
tyrosine
493
MTT
456
serine
444
TNF
402
calcium
365
MDA
305
methionine
298
Insulin
285
AMP
282
water
279
more...