Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P42345 (mTOR)
26,049 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
mTOR 26049
PI3K 4856
AKT 4378
Mol 2655
insulin 1789
Sep 1559
AMPK 1249
MAPK 1215
ERK 1170
S6K1 1123
p53 1099
LC3 1078
4E-BP1 1076
phosphatidylinositol 3-kinase 1035
PTEN 945
protein kinase B 930
caspase-3 912
AMP-activated protein kinase 784
Bcl-2 739
phosphoinositide 3-kinase 730
more...
Disease
cancer 7700
tumor 5265
breast cancer 1380
tumor growth 1317
tumorigenesis 1078
tuberous sclerosis 954
diabetes 777
hepatocellular carcinoma 735
renal cell carcinoma 636
obesity 615
carcinoma 554
lung cancer 532
tumor progression 531
carcinogenesis 515
prostate cancer 506
metastases 437
leukemia 417
colorectal cancer 411
Alzheimer's disease 384
melanoma 358
more...
Symptom
starvation 419
seizures 253
pain 141
fatigue 83
functional recovery 68
diarrhea 66
cachexia 52
exhaustion 52
collapse 38
weakness 34
anesthesia 31
overweight 27
anorexia 24
ataxia 23
splenomegaly 17
nausea 17
hypothermia 16
dyspnea 16
cough 15
memory loss 13
more...
Drug
Everolimus 350
ROS 327
NVP 199
Dermatol 114
IL-2 103
lysine 93
Sorafenib 83
Monit 74
MAP 73
Cardiovasc 52
Imatinib 43
Herceptin 43
Parkin 35
Parkin 35
Bevacizumab 34
CSF 30
3-Methyladenine 26
Gefitinib 25
NADH 24
Cetuximab 23
more...
Enzyme
mitogen-activated protein kinase 2647
ERK 2431
AMP-activated protein kinase 1962
protein kinase 1578
AMPK 1266
AMPK 1249
phosphatidylinositol 3-kinase 1035
MEK 880
focal adhesion kinase 788
phosphoinositide 3-kinase 730
caspase-3 641
calcineurin 433
proteasome 408
PARP 394
protein kinase C 315
luciferase 264
GSK 260
PDK1 210
superoxide dismutase 169
TOR 161
more...
Compound
Dec 1663
glucose 1567
DNA 1420
oxygen 1247
Rapamycin 1170
Clin 891
MEK 717
ATP 679
threonine 515
leucine 500
tyrosine 493
MTT 456
serine 444
TNF 402
calcium 365
MDA 305
methionine 298
Insulin 285
AMP 282
water 279
more...