Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P41181 (collecting duct)
5,183 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collecting duct 5183
vasopressin 865
proximal tubule 552
ATPase 540
aquaporin 436
Sep 324
ENaC 295
water channel 293
arginine vasopressin 287
sodium channel 213
ATP 168
Mol 155
AQP2 145
renin 143
aquaporin 2 142
angiotensin II 103
ROMK 98
AVP 94
insulin 82
NDI 77
mineralocorticoid receptor 77
carbonic anhydrase 75
lectin 73
pendrin 73
AQP3 73
CO2 72
AQP2 protein 71
NKCC2 69
atrial natriuretic peptide 65
anion exchanger 62
AMP 61
bradykinin 59
endoplasmic reticulum 58
brush border 57
AQP1 56
nitric oxide synthase 56
PKA 56
adenylate cyclase 56
adenosinetriphosphatase 55
collagen 54
glycoprotein 54
natriuretic peptide 52
AQP4 50
mm-1 50
adenylyl cyclase 50
atrial natriuretic factor 49
AE1 49
Ang II 46
cyclooxygenase 45
endothelin-1 45
phosphodiesterase 43
aquaporin-3 43
CCD 41
p38 40
parathyroid hormone 40
X-linked 40
ET-1 40
ERK 40
NHE3 39
albumin 39
epidermal growth factor 39
Gen 39
PKC 38
vimentin 38
CHIP28 37
Arginine vasopressin 37
membrane protein 36
ANG 36
calmodulin 35
MAPK 35
Nedd4-2 33
cytokeratin 33
Pendrin 32
E-cadherin 32
ERK1 31
cystic fibrosis transmembrane conductance regulator 31
oxytocin 31
polypeptide 29
fetal kidney 29
renin receptor 28
more...
Disease
hypertension 286
nephrogenic diabetes insipidus 194
carcinoma 193
tumor 177
renal cell carcinoma 169
polycystic kidney 142
renal disease 96
dehydration 90
cancer 84
antidiuresis 81
renal failure 73
renal tubular acidosis 68
diabetes insipidus 66
diabetes 64
wasting 55
ureter 52
nephrotic syndrome 48
heart failure 45
congestive heart failure 43
metabolic alkalosis 42
cirrhosis 41
proteinuria 41
CCD 41
CCD 41
metastases 40
Bellini duct carcinoma 38
Luminal 38
hyperosmolality 36
ischemia 35
renal cyst 34
alkalosis 34
pertussis 32
acute renal failure 31
hypercalciuria 30
chronic renal failure 27
renal cancer 27
Bartter's syndrome 26
SEM 26
diabetic nephropathy 26
hypercalcemia 24
nephrolithiasis 22
WT1 22
dysplasia 22
Autosomal dominant polycystic kidney disease 22
adenoma 21
ADH 21
ATM 21
hypernatremia 20
Liddle's syndrome 20
pyelonephritis 18
nephrocalcinosis 17
NAME 17
Autosomal recessive polycystic kidney disease 17
aldosteronism 16
azotemia 16
SDS 16
acute tubular necrosis 15
fluid overload 15
glomerulosclerosis 15
Congenital nephrogenic diabetes insipidus 15
renal insufficiency 14
transitional cell carcinoma 14
urinary tract obstruction 14
type 2 diabetes 14
Hippel 14
carcinogenesis 14
deafness 13
NDI 13
hydronephrosis 13
cystic fibrosis 13
glomerulonephritis 13
bipolar disorder 12
respiratory acidosis 12
epididymis 12
cold 12
PDS 12
urolithiasis 11
renal ischemia 11
genetic disorder 11
Steroids 10
more...
Symptom
polyuria 137
polydipsia 40
hypercapnia 6
functional recovery 5
back pain 5
collapse 5
weakness 5
oliguria 4
diarrhea 4
acidity 4
seizures 4
anesthesia 4
fatigue 4
vomiting 4
constipation 3
Macula 3
flank pain 3
anorexia 3
low back pain 3
cough 2
tremor 2
pain 2
dizziness 2
dyspnea 2
lethargy 2
rundown 2
excessive urination 2
flushing 2
tinnitus 1
Decreased activity 1
chest tightness 1
abdominal fullness 1
starvation 1
acute stress 1
Cushingoid 1
hunger 1
male puberty 1
persistent cough 1
abdominal pain 1
exhaustion 1
ketonuria 1
enuresis 1
Cushingoid 1
splenomegaly 1
hypocapnia 1
syncope 1
renal colic 1
respiratory distress 1
headache 1
bitter taste 1
shortness of breath 1
ataxia 1
numbness 1
Drug
Nephron 54
Nephron 48
lysine 46
Amiloride 43
Amiloride 43
NH3 33
Angiotensin II 23
ETA 19
Ouabain 16
Forskolin 14
Cardiovasc 13
Dial 12
DDAVP 12
DDAVP 11
Leaf 9
Indomethacin 9
NADH 9
Ringer's solution 8
caffeine 7
Tolvaptan 7
MAP 6
Glucagon 5
ICI 5
Gel 5
Sulprostone 5
Albumin 5
citric acid 4
Bosentan 4
PTH 4
CAM 4
Bosentan 4
IFN-gamma 4
NAG 4
Asn 4
Bumetanide 4
ROS 3
ETS 3
Hydrochlorothiazide 3
Retinoic acid 3
Aliskiren 3
KGF 3
Monit 3
ABC 2
Demeclocycline 2
Clopidogrel 2
nitroglycerin 2
Captopril 2
Felodipine 2
Fenoldopam 2
Sodium nitroprusside 2
Valsartan 2
IL-2 2
AmBisome 2
Nitric Oxide 2
Growth hormone 2
Ethanol 2
Iloprost 2
EE2 2
Chlorothiazide 2
Helium 2
Adriamycin 2
Growth hormone 2
DNase I 2
Glycerol 2
RPH 2
Estrogens 2
Troglitazone 1
Roflumilast 1
Taxol 1
DOCP 1
niacin 1
Erlotinib 1
Torasemide 1
Adenosine triphosphate 1
Phosphoramidon 1
Glutathione 1
CTA 1
Alanine 1
CTC 1
Carbenoxolone 1
more...
Enzyme
ATPase 573
protein kinase 215
renin 143
protein kinase C 134
mitogen-activated protein kinase 104
ERK 81
carbonic anhydrase 74
luciferase 58
adenylate cyclase 57
phospholipase C 44
phosphodiesterase 43
NO synthase 36
guanylate cyclase 35
peroxidase 30
MEK 25
collagenase 24
kallikrein 24
glutathione S-transferase 22
RNase 22
RNase 22
alcohol dehydrogenase 21
ADH 21
reverse transcriptase 21
11beta-hydroxysteroid dehydrogenase 20
caspase-3 19
PKG 17
aldose reductase 17
trypsin 16
phosphatidylinositol 3-kinase 16
CD10 16
ACE 16
calcineurin 16
H,K-ATPase 15
NADPH oxidase 13
NADPH oxidase 13
phospholipase A2 13
proteasome 13
RNA polymerase 13
plasmin 13
alkaline phosphatase 12
AMP-activated protein kinase 12
prostasin 12
ribonuclease 11
ribonuclease 11
DCF 11
HSD 10
AMPK 10
transcriptase 10
ubiquitin-protein ligase 10
CPT 9
beta-galactosidase 9
urokinase-type plasminogen activator 9
pyruvate kinase 9
CPT 9
gamma-glutamyl transpeptidase 9
CPT 9
focal adhesion kinase 9
ATP synthase 8
succinate dehydrogenase 8
furin 8
GSK 8
fumarase 8
tissue kallikrein 7
cathepsin D 7
hyaluronidase 7
hyaluronidase 7
glutamine synthetase 7
cGMP phosphodiesterase 7
phosphoinositide 3-kinase 7
malate dehydrogenase 6
NOS 6
glyceraldehyde-3-phosphate dehydrogenase 6
phosphoenolpyruvate carboxykinase 6
PDE 6
sorbitol dehydrogenase 6
phosphoenolpyruvate carboxykinase 6
MIP 6
phosphoenolpyruvate carboxykinase 6
superoxide dismutase 5
myosin light chain kinase 5
more...
Compound
water 1332
sodium 1202
aldosterone 500
cAMP 384
Dec 375
calcium 371
potassium 350
urea 347
salt 340
Clin 311
carbonate 186
ATP 168
Vasopressin 154
DNA 121
arginine 114
ammonium 98
ammonia 96
glucose 94
HCO 92
phosphate 90
nitric oxide 89
cGMP 89
CO2 87
hydrogen 82
creatinine 77
NH2 75
serine 72
PGE2 71
acetate 69
AMP 65
oxygen 60
lysine 55
sodium chloride 51
tyrosine 50
Lithium 43
Amiloride 43
PGE 42
Sodium 41
Luminal 39
oxalate 34
alanine 34
Angiotensin II 32
DIDS 31
galactose 31
glycerol 31
threonine 31
ADP 30
nitrogen 30
sulfate 29
ADP 28
ADP 27
Ang II 26
UTP 23
Mg2+ 22
proline 22
DOCA 22
alcohol dehydrogenase 21
leucine 21
methionine 21
MEK 19
ETA 19
vitamin D 18
barium 18
NPPB 18
GMP 17
SDS 17
Salix 17
Ouabain 16
His 16
mercury 16
cysteine 15
bromide 15
GTP 15
Insulin 15
HCl 14
benzoic acid 14
betaine 14
Dopamine 14
NAD 14
PNA 14
more...