Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P41181 (
collecting duct
)
5,183
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
collecting duct
5183
vasopressin
865
proximal tubule
552
ATPase
540
aquaporin
436
Sep
324
ENaC
295
water channel
293
arginine vasopressin
287
sodium channel
213
ATP
168
Mol
155
AQP2
145
renin
143
aquaporin 2
142
angiotensin II
103
ROMK
98
AVP
94
insulin
82
NDI
77
mineralocorticoid receptor
77
carbonic anhydrase
75
lectin
73
pendrin
73
AQP3
73
CO2
72
AQP2 protein
71
NKCC2
69
atrial natriuretic peptide
65
anion exchanger
62
AMP
61
bradykinin
59
endoplasmic reticulum
58
brush border
57
AQP1
56
nitric oxide synthase
56
PKA
56
adenylate cyclase
56
adenosinetriphosphatase
55
collagen
54
glycoprotein
54
natriuretic peptide
52
AQP4
50
mm-1
50
adenylyl cyclase
50
atrial natriuretic factor
49
AE1
49
Ang II
46
cyclooxygenase
45
endothelin-1
45
phosphodiesterase
43
aquaporin-3
43
CCD
41
p38
40
parathyroid hormone
40
X-linked
40
ET-1
40
ERK
40
NHE3
39
albumin
39
epidermal growth factor
39
Gen
39
PKC
38
vimentin
38
CHIP28
37
Arginine vasopressin
37
membrane protein
36
ANG
36
calmodulin
35
MAPK
35
Nedd4-2
33
cytokeratin
33
Pendrin
32
E-cadherin
32
ERK1
31
cystic fibrosis transmembrane conductance regulator
31
oxytocin
31
polypeptide
29
fetal kidney
29
renin receptor
28
more...
Disease
hypertension
286
nephrogenic diabetes insipidus
194
carcinoma
193
tumor
177
renal cell carcinoma
169
polycystic kidney
142
renal disease
96
dehydration
90
cancer
84
antidiuresis
81
renal failure
73
renal tubular acidosis
68
diabetes insipidus
66
diabetes
64
wasting
55
ureter
52
nephrotic syndrome
48
heart failure
45
congestive heart failure
43
metabolic alkalosis
42
cirrhosis
41
proteinuria
41
CCD
41
CCD
41
metastases
40
Bellini duct carcinoma
38
Luminal
38
hyperosmolality
36
ischemia
35
renal cyst
34
alkalosis
34
pertussis
32
acute renal failure
31
hypercalciuria
30
chronic renal failure
27
renal cancer
27
Bartter's syndrome
26
SEM
26
diabetic nephropathy
26
hypercalcemia
24
nephrolithiasis
22
WT1
22
dysplasia
22
Autosomal dominant polycystic kidney disease
22
adenoma
21
ADH
21
ATM
21
hypernatremia
20
Liddle's syndrome
20
pyelonephritis
18
nephrocalcinosis
17
NAME
17
Autosomal recessive polycystic kidney disease
17
aldosteronism
16
azotemia
16
SDS
16
acute tubular necrosis
15
fluid overload
15
glomerulosclerosis
15
Congenital nephrogenic diabetes insipidus
15
renal insufficiency
14
transitional cell carcinoma
14
urinary tract obstruction
14
type 2 diabetes
14
Hippel
14
carcinogenesis
14
deafness
13
NDI
13
hydronephrosis
13
cystic fibrosis
13
glomerulonephritis
13
bipolar disorder
12
respiratory acidosis
12
epididymis
12
cold
12
PDS
12
urolithiasis
11
renal ischemia
11
genetic disorder
11
Steroids
10
more...
Symptom
polyuria
137
polydipsia
40
hypercapnia
6
functional recovery
5
back pain
5
collapse
5
weakness
5
oliguria
4
diarrhea
4
acidity
4
seizures
4
anesthesia
4
fatigue
4
vomiting
4
constipation
3
Macula
3
flank pain
3
anorexia
3
low back pain
3
cough
2
tremor
2
pain
2
dizziness
2
dyspnea
2
lethargy
2
rundown
2
excessive urination
2
flushing
2
tinnitus
1
Decreased activity
1
chest tightness
1
abdominal fullness
1
starvation
1
acute stress
1
Cushingoid
1
hunger
1
male puberty
1
persistent cough
1
abdominal pain
1
exhaustion
1
ketonuria
1
enuresis
1
Cushingoid
1
splenomegaly
1
hypocapnia
1
syncope
1
renal colic
1
respiratory distress
1
headache
1
bitter taste
1
shortness of breath
1
ataxia
1
numbness
1
Drug
Nephron
54
Nephron
48
lysine
46
Amiloride
43
Amiloride
43
NH3
33
Angiotensin II
23
ETA
19
Ouabain
16
Forskolin
14
Cardiovasc
13
Dial
12
DDAVP
12
DDAVP
11
Leaf
9
Indomethacin
9
NADH
9
Ringer's solution
8
caffeine
7
Tolvaptan
7
MAP
6
Glucagon
5
ICI
5
Gel
5
Sulprostone
5
Albumin
5
citric acid
4
Bosentan
4
PTH
4
CAM
4
Bosentan
4
IFN-gamma
4
NAG
4
Asn
4
Bumetanide
4
ROS
3
ETS
3
Hydrochlorothiazide
3
Retinoic acid
3
Aliskiren
3
KGF
3
Monit
3
ABC
2
Demeclocycline
2
Clopidogrel
2
nitroglycerin
2
Captopril
2
Felodipine
2
Fenoldopam
2
Sodium nitroprusside
2
Valsartan
2
IL-2
2
AmBisome
2
Nitric Oxide
2
Growth hormone
2
Ethanol
2
Iloprost
2
EE2
2
Chlorothiazide
2
Helium
2
Adriamycin
2
Growth hormone
2
DNase I
2
Glycerol
2
RPH
2
Estrogens
2
Troglitazone
1
Roflumilast
1
Taxol
1
DOCP
1
niacin
1
Erlotinib
1
Torasemide
1
Adenosine triphosphate
1
Phosphoramidon
1
Glutathione
1
CTA
1
Alanine
1
CTC
1
Carbenoxolone
1
more...
Enzyme
ATPase
573
protein kinase
215
renin
143
protein kinase C
134
mitogen-activated protein kinase
104
ERK
81
carbonic anhydrase
74
luciferase
58
adenylate cyclase
57
phospholipase C
44
phosphodiesterase
43
NO synthase
36
guanylate cyclase
35
peroxidase
30
MEK
25
collagenase
24
kallikrein
24
glutathione S-transferase
22
RNase
22
RNase
22
alcohol dehydrogenase
21
ADH
21
reverse transcriptase
21
11beta-hydroxysteroid dehydrogenase
20
caspase-3
19
PKG
17
aldose reductase
17
trypsin
16
phosphatidylinositol 3-kinase
16
CD10
16
ACE
16
calcineurin
16
H,K-ATPase
15
NADPH oxidase
13
NADPH oxidase
13
phospholipase A2
13
proteasome
13
RNA polymerase
13
plasmin
13
alkaline phosphatase
12
AMP-activated protein kinase
12
prostasin
12
ribonuclease
11
ribonuclease
11
DCF
11
HSD
10
AMPK
10
transcriptase
10
ubiquitin-protein ligase
10
CPT
9
beta-galactosidase
9
urokinase-type plasminogen activator
9
pyruvate kinase
9
CPT
9
gamma-glutamyl transpeptidase
9
CPT
9
focal adhesion kinase
9
ATP synthase
8
succinate dehydrogenase
8
furin
8
GSK
8
fumarase
8
tissue kallikrein
7
cathepsin D
7
hyaluronidase
7
hyaluronidase
7
glutamine synthetase
7
cGMP phosphodiesterase
7
phosphoinositide 3-kinase
7
malate dehydrogenase
6
NOS
6
glyceraldehyde-3-phosphate dehydrogenase
6
phosphoenolpyruvate carboxykinase
6
PDE
6
sorbitol dehydrogenase
6
phosphoenolpyruvate carboxykinase
6
MIP
6
phosphoenolpyruvate carboxykinase
6
superoxide dismutase
5
myosin light chain kinase
5
more...
Compound
water
1332
sodium
1202
aldosterone
500
cAMP
384
Dec
375
calcium
371
potassium
350
urea
347
salt
340
Clin
311
carbonate
186
ATP
168
Vasopressin
154
DNA
121
arginine
114
ammonium
98
ammonia
96
glucose
94
HCO
92
phosphate
90
nitric oxide
89
cGMP
89
CO2
87
hydrogen
82
creatinine
77
NH2
75
serine
72
PGE2
71
acetate
69
AMP
65
oxygen
60
lysine
55
sodium chloride
51
tyrosine
50
Lithium
43
Amiloride
43
PGE
42
Sodium
41
Luminal
39
oxalate
34
alanine
34
Angiotensin II
32
DIDS
31
galactose
31
glycerol
31
threonine
31
ADP
30
nitrogen
30
sulfate
29
ADP
28
ADP
27
Ang II
26
UTP
23
Mg2+
22
proline
22
DOCA
22
alcohol dehydrogenase
21
leucine
21
methionine
21
MEK
19
ETA
19
vitamin D
18
barium
18
NPPB
18
GMP
17
SDS
17
Salix
17
Ouabain
16
His
16
mercury
16
cysteine
15
bromide
15
GTP
15
Insulin
15
HCl
14
benzoic acid
14
betaine
14
Dopamine
14
NAD
14
PNA
14
more...