Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P41181 (collecting duct)
 5,183 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PCD9 12.6
VIT32 12.6
collecting duct 12.6
Rh type B glycoprotein 12.6
xGPAT1 12.6
FHAD1 12.6
COMMD2 12.6
synaptotagmin VIII 12.6
VIP32 12.6
AQP2 protein 12.1
KIAA1185 11.6
V-ATPase B1 subunit 11.6
Aquaporin-2 mutant 11.6
RCCD1 11.6
chloride channel CLC-5 11.6
Histone H4 gene 11.6
aquaporin 2 11.5
MIWC 11.4
cGMP-gated cation channel protein 11.3
dyf-13 11.0
aquaporin 6 11.0
glycerophosphodiester phosphodiesterase domain containing 5 11.0
Transmembrane protein 174 11.0
AQP2 11.0
Aquaporin adipose 10.9
UT-A2 10.8
RNF183 10.7
ENaCalpha 10.6
N4WBP5A 10.6
ENaCgamma 10.6
kinesin family member 3B 10.6
TMEM51 10.6
AE2 anion exchanger 10.5
GPR80 10.5
aquaporin-3 10.4
MCD4 10.4
ROMK 10.4
ClC-K2 10.4
AKAP18 10.4
CHIP28 10.3
phosphodiesterase 4C 10.3
COMMD9 10.3
VPP1 10.3
IBA2 10.3
PRKWNK4 10.3
pendrin 10.2
UT2 10.1
Pendrin 10.1
ENaCbeta 10.0
DAPL1 10.0
P2Y2-like 10.0
AVPR2 10.0
B/K protein 10.0
TTC26 10.0
Receptor activity-modifying protein 3 10.0
38KD 10.0
MOX1 10.0
Na,K-ATPase gamma subunit 10.0
collagen type IV alpha 2 10.0
MAPKBP1 10.0
NHE4 9.9
Ksp-cadherin 9.9
ATP6B1 9.9
NBC3 9.9
ENaC 9.8
SLC4A5 9.8
BSC1 9.8
ERAP140 9.8
bumetanide-sensitive Na-K-2Cl cotransporter 9.8
CNKSR3 9.8
EMI domain-containing protein 2 9.8
arginine vasopressin V2 receptor 9.8
COMMD3 9.8
aquaporin 9.7
CHIF 9.7
AQP3 9.7
ATP6V0A4 9.7
AQP3 protein 9.7
HUT11 9.7
Kir1.1 9.7
Tonicity-responsive enhancer binding protein 9.7
adenylyl cyclase type VI 9.7
AE4 9.7
ClC-K1 9.6
amiloride-sensitive sodium channel 9.6
DD96 9.6
ATP6V1G3 9.6
NAIP protein 9.6
gamma hENaC 9.6
NCOA7 9.6
water channel 9.5
NKCC2 9.4
ATP6V1B1 9.4
Nedd4-2 9.4
mitogen-activated protein kinase kinase kinase 7 9.4
SLC4A8 9.4
BTR1 9.4
ROAT1 9.4
TMOD1 9.4
FXYD5 9.4
HLPR 9.4
NSF protein 9.4
Na(+)/H(+) exchanger 3 9.3
cGMP-gated cation channel 9.3
GDPD5 9.3
Cellubrevin 9.3
NFAT5 protein 9.3
OCRL-1 9.3
AQP11 9.2
AQP7 9.2
glucocorticoid-induced leucine zipper protein 9.2
collectrin 9.2
kanadaptin 9.1
SLC22A17 9.1
Aquaporin-7 9.1
OTUD4 9.1
NHE-3 9.1
anion exchanger 1 9.0
aquaporin 3 9.0
fibrocystin 9.0
UTE 9.0
SLC13A2 9.0
sodium bicarbonate cotransporter 9.0
prominin-2 9.0
LAT4 9.0
KCNJ1 9.0
SLC12A3 9.0
ATP1AL1 8.9
mm-1 8.9
NDI 8.9
prostasin 8.9
barttin 8.9
PKK2 8.9
R37A 8.9
NEK8 8.9
VMA4 8.9
VR-OAC 8.9
SLC14A1 8.9
KLHL3 8.8
AQP1 8.8
tonicity-responsive enhancer binding protein 8.8
adenylate cyclase 6 8.8
Foxl1 8.8
Nek8 8.8
ATP4B 8.8
K79 8.8
NBCe2 8.7
TonEBP 8.7
NEDD4-2 8.7
CYS1 8.7
FAM64A 8.7
dysadherin 8.6
proximal tubule 8.6
renin receptor 8.6
polaris 8.6
polycystic kidney and hepatic disease 1 8.6
adenosinetriphosphatase 8.6
ARPKD 8.6
paracingulin 8.6
CHAR 8.6
more...
Disease
Acquired nephrogenic diabetes insipidus 11.6
Renal coccidiosis 11.0
Congenital nephrogenic diabetes insipidus 10.8
Bellini duct carcinoma 10.6
Familial central diabetes insipidus 10.6
nephrogenic diabetes insipidus 10.3
NSIAD 10.3
Chronic hyperkalemia 10.3
FH II 10.0
Metanephric adenofibroma 10.0
Chromophobe cell renal carcinoma 9.4
Distal renal tubular acidosis 9.4
Liddle's syndrome 9.2
antidiuresis 9.2
Colonic pseudo-obstruction 8.8
Autosomal recessive polycystic kidney disease 8.7
NPHP2 8.6
Polyomavirus-associated nephropathy 8.6
PHA2 8.6
Gordon's syndrome 8.4
Cystic kidney disease 8.3
Renal oncocytoma 8.2
Renal tubular dysfunction 8.0
hyperosmolality 7.9
Dent's disease 7.9
NDI 7.9
Ask-Upmark kidney 7.8
sponge kidney 7.8
Hereditary Leiomyomatosis and Renal Cell Cancer 7.7
Mesoblastic nephroma 7.7
renal tubular acidosis 7.7
pelvic neoplasm 7.6
polycystic kidney 7.5
gouty nephropathy 7.5
Pseudohypoaldosteronism 7.5
renal papillary necrosis 7.5
MKS3 7.5
NPHP3 7.4
BSND 7.3
Bartter's syndrome 7.3
metabolic alkalosis 7.2
pancreatic gastrinoma 7.2
Autosomal dominant polycystic kidney disease 7.2
NPHP1 7.1
renal cyst 7.1
hypo-osmolality 7.1
BK virus nephropathy 7.0
Luminal 7.0
synchronous neoplasms 7.0
Psammoma 6.9
Acute pyelonephritis 6.9
Oncocytoma 6.8
Oncocytoma 6.8
diabetes insipidus 6.8
Oncocytoma 6.8
Gitelman syndrome 6.7
uricosuria 6.7
hyporeninemic hypoaldosteronism 6.7
Benign neoplasms 6.7
Benign neoplasms 6.7
Ureter 6.7
Ureter 6.7
Metanephric adenoma 6.5
Familial hypocalciuric hypercalcemia 6.5
alkalosis 6.5
Renal interstitial fibrosis 6.5
Ovarian metastasis 6.5
potassium deficiency 6.4
BHD 6.4
Ureteral obstruction 6.3
urinary tract obstruction 6.3
Central diabetes insipidus 6.3
hypernatremia 6.2
hypercalciuria 6.2
Heck's disease 6.2
nephrocalcinosis 6.2
kidney tumor 6.1
Azotemia 6.1
Tubulointerstitial nephritis 6.1
BK virus infection 6.1
PDS 6.0
Hajdu-Cheney syndrome 6.0
renal glycosuria 6.0
Androgen deficiency 6.0
kidney hypertrophy 5.9
BHD 5.9
ADH 5.9
azotemia 5.8
Hypokalemic periodic paralysis 5.8
BCD 5.8
glomerulitis 5.7
CCD 5.7
Kidney Cancer 5.7
PCT 5.7
hydroxyapatite deposition 5.7
Collet-Sicard syndrome 5.7
nephrolithiasis 5.7
hypochloremia 5.6
CCD 5.6
respiratory acidosis 5.6
SIADH 5.6
bladder neoplasm 5.6
Medullary carcinoma 5.6
renal cell carcinoma 5.5
hypoaldosteronism 5.5
fluid overload 5.5
familial disorder 5.5
acute tubular necrosis 5.4
wasting 5.4
ureteritis 5.3
endolymphatic hydrops 5.3
genetic hypertension 5.2
hypokalemic alkalosis 5.2
Emphysematous pyelonephritis 5.2
Minimal change disease 5.2
Ogilvie's syndrome 5.1
renal cancer 5.1
ureter 5.0
phosphaturia 5.0
aldosteronism 5.0
chylopericardium 5.0
angiomyolipoma 4.9
MCD 4.9
PAPA 4.9
nephrotic syndrome 4.9
Heymann nephritis 4.8
NPHS2 4.8
Goldblatt 4.8
nephrosis 4.8
clear cell carcinoma 4.8
renal ischemia 4.7
diabetic hyperglycemia 4.7
Simpson-Golabi-Behmel syndrome 4.7
chronic cystitis 4.7
porphyria cutanea tarda 4.7
interstitial nephritis 4.6
tubular necrosis 4.6
Bubo 4.6
dehydration 4.5
Chronic heart failure 4.5
angiolipoma 4.5
nephrosclerosis 4.5
transitional cell carcinoma 4.4
uropathy 4.4
Silence 4.4
hyperoxaluria 4.3
papillitis 4.3
habitual abortion 4.3
hypertensive nephropathy 4.3
hypermagnesemia 4.3
Hippel 4.3
malignant hypertension 4.2
pH increased 4.2
IBR 4.2
hepatorenal syndrome 4.2
pyelonephritis 4.2
EKC 4.2
NPS 4.1
Lowe syndrome 4.1
urolithiasis 4.1
more...
Symptom
excessive urination 9.6
polyuria 8.1
Macula 7.3
polydipsia 6.8
male puberty 6.1
Cushingoid 4.8
Cushingoid 4.8
rundown 4.6
abdominal fullness 3.9
oliguria 3.7
Decreased activity 3.5
ketonuria 3.5
persistent cough 3.3
flank pain 3.1
chest tightness 3.0
renal colic 2.9
hypercapnia 2.2
bitter taste 2.1
enuresis 1.9
hypocapnia 1.9
back pain 1.3
functional recovery 1.2
lethargy 1.1
flushing 0.9
low back pain 0.9
constipation 0.8
acidity 0.7
anorexia 0.4
acute stress 0.4
dizziness 0.3
numbness 0.2
shortness of breath 0.2
hunger 0.1
collapse 0.1
tinnitus -0.1
weakness -0.3
vomiting -0.4
tremor -0.6
syncope -0.6
splenomegaly -0.7
cough -1.0
fatigue -1.1
exhaustion -1.2
dyspnea -1.2
diarrhea -1.2
ataxia -1.4
respiratory distress -1.7
seizures -1.7
starvation -2.0
anesthesia -2.2
abdominal pain -2.3
headache -3.2
pain -4.4
Drug
DOCP 9.6
Demeclocycline 8.2
Micardis 8.1
Imidafenacin 8.1
Sulprostone 7.9
RPH 7.8
Camostat mesilate 7.8
Tolvaptan 7.6
Amiloride 7.4
Amiloride 7.2
Piretanide 6.9
Parecoxib 6.8
Butaprost 6.6
Nafamostat mesilate 6.6
Chlorothiazide 6.6
DDAVP 6.3
Aliskiren 6.1
DDAVP 6.1
Fenoldopam 6.0
Torasemide 5.9
Bumetanide 5.9
Bosentan 5.9
Bosentan 5.9
Plavix 5.6
Roflumilast 5.6
Roflumilast 5.6
Hydrochlorothiazide 5.5
ETA 5.4
Ouabain 5.3
KGF 5.3
Atipamezole 5.2
Felodipine 5.1
Forskolin 5.0
Carbenoxolone 5.0
Olmesartan 4.9
Diamminedichloroplatinum 4.9
NH3 4.8
Phosphoramidon 4.8
Angiotensin II 4.8
Valsartan 4.7
Nephron 4.6
AmBisome 4.6
Iloprost 4.5
Pitressin 4.5
KCL 4.5
Helium 4.3
Vena 4.3
Vena 4.3
Nephron 4.2
AC2 4.2
Ringer's solution 4.1
MDM 3.9
Rolipram 3.8
Hyaluronidase 3.8
Viagra 3.7
Sodium nitroprusside 3.7
EHDP 3.6
Hyaluronidase 3.6
Troglitazone 3.5
NAG 3.5
Clopidogrel 3.5
Viagra 3.4
Urokinase 3.3
R1881 3.3
Adenosine deaminase 3.2
Everolimus 3.1
Indomethacin 3.1
Secretin 3.1
Glucagon 3.0
Erlotinib 3.0
ETS 2.8
Adenosine triphosphate 2.8
Aprotinin 2.7
Monensin 2.7
Albumin 2.7
PFA 2.6
Diphenhydramine 2.6
CTC 2.5
ICI 2.5
Estrogens 2.4
Retinoic acid 2.4
Captopril 2.4
Glycerol 2.4
CoCl2 2.3
CoCl2 2.3
DPA 2.3
lysine 2.3
CTC 2.3
Nitric Oxide 2.2
IL-1ra 2.2
CTA 2.1
Glycyrrhiza 2.1
CAM 2.1
Growth hormone 2.0
Growth hormone 2.0
MgSO4 2.0
Activin 1.9
PTH 1.9
PTC 1.8
Fructose 1.7
uPA 1.5
Propofol 1.5
Paraffin 1.5
G418 1.5
Adriamycin 1.4
CDP 1.4
Leaf 1.4
NADH 1.3
citric acid 1.3
Dial 1.3
MAP 1.2
Fluorescein 1.2
Alanine 1.1
ALA 1.1
Asn 1.1
Gel 1.0
IFN-beta 1.0
caffeine 1.0
Heme 1.0
Taxol 0.9
Atropine 0.9
MRC 0.8
Fluorescein 0.7
niacin 0.7
EE2 0.7
DNase I 0.6
ABC 0.5
nitroglycerin 0.5
Ethanol 0.3
Glutathione 0.2
Histamine 0.1
CTX 0.1
CTX 0.1
CaCl2 -0.0
CaCl2 -0.0
ROS -0.1
CaCl2 -0.1
IFN-gamma -0.2
THF -0.4
Biopolymers -0.5
CTX -0.7
Monit -0.9
IL-2 -1.2
Cardiovasc -1.3
lactose -1.4
Enzyme
prostasin 9.0
site-1 protease 8.4
H,K-ATPase 8.3
glycerophosphocholine phosphodiesterase 8.0
RPH 7.9
site-1 protease 7.4
11beta-hydroxysteroid dehydrogenase 6.6
ubiquitin-protein ligase 6.3
gluconate dehydrogenase 6.1
matrix metalloproteinase 14 6.1
carbonic anhydrase 5.9
ketohexokinase 5.9
ADH 5.9
DAP II 5.8
alpha-methylacyl-CoA racemase 5.8
ATPase 5.8
AMP-activated kinase 5.7
N-acetylgalactosaminidase 5.5
cGMP phosphodiesterase 5.5
fumarase 5.4
PKG 5.4
oxaloacetate decarboxylase 5.2
sorbitol dehydrogenase 5.1
DCF 5.1
tissue kallikrein 5.1
aldose reductase 5.0
PIP kinase 4.9
phosphocholine cytidylyltransferase 4.8
aminopeptidase B 4.8
proton-translocating ATPase 4.8
inositol 3-kinase 4.7
oxytocinase 4.7
sphingomyelin synthase 4.7
endo-N 4.7
ornithine aminotransferase 4.7
guanylate cyclase 4.7
estrogen sulfotransferase 4.7
renin 4.6
kallikrein 4.6
ADH3 4.6
HK2 4.5
citrate lyase 4.5
biliverdin reductase 4.5
1-hydroxylase 4.4
caspase-7 4.4
LTA4 hydrolase 4.3
caspase-7 4.3
uridine phosphorylase 4.3
dimethylarginine dimethylaminohydrolase 4.3
15-hydroxyprostaglandin dehydrogenase 4.3
adenylate cyclase 4.2
HSD 4.1
CPT 4.1
protein kinase C 4.1
nucleotide pyrophosphatase 4.0
protein kinase 4.0
prostacyclin synthase 4.0
CPT 4.0
cathepsin C 4.0
furin 3.9
3'-exonuclease 3.9
PST 3.9
phospholipase C 3.9
aminopeptidase A 3.9
phosphodiesterase 3.8
NO synthase 3.8
alcohol dehydrogenase 3.8
purine nucleoside phosphorylase 3.7
DMT 3.7
CPT 3.6
angiotensin-converting enzyme 2 3.6
apyrase 3.6
neuropathy target esterase 3.5
aromatic L-amino acid decarboxylase 3.5
myosin light chain kinase 3.5
ADPase 3.5
estrogen sulfotransferase 3.5
isopeptidase 3.4
pyruvate kinase 3.4
cathepsin D 3.4
ribonuclease 3.4
ribonuclease 3.4
prolyl hydroxylase 3.3
endoglycosidase H 3.3
CD10 3.3
PDE 3.3
glutaminase 3.3
endothelin-converting enzyme 3.3
hyaluronidase 3.2
luciferase 3.2
AMP deaminase 3.2
phosphatidylinositol 3-kinase 3.2
plasmin 3.1
phosphoenolpyruvate carboxykinase 3.1
phosphoenolpyruvate carboxykinase 3.1
glutamine synthetase 3.1
MEK 3.1
RNase 3.0
sphingosine kinase 3.0
protein phosphatase 2A 3.0
collagenase 3.0
malate dehydrogenase 3.0
caspase-2 3.0
phosphoenolpyruvate carboxykinase 3.0
sucrose synthase 3.0
TMT 3.0
NADPH oxidase 3.0
caspase-2 2.9
SPS 2.9
m-calpain 2.9
RNase 2.9
MIP 2.9
phosphoinositide 3-kinase 2.9
GSK 2.9
NADPH oxidase 2.8
ATP synthase 2.8
hyaluronidase 2.8
citrate synthase 2.8
prostaglandin synthetase 2.7
mitogen-activated protein kinase 2.7
cathepsin K 2.7
arginase 2.7
3beta-hydroxysteroid dehydrogenase 2.7
adenosine kinase 2.7
TdT 2.7
transcriptase 2.7
diacylglycerol kinase 2.6
gamma-glutamyl transpeptidase 2.6
CaMKII 2.6
RNase III 2.6
succinate dehydrogenase 2.6
glutathione S-transferase 2.6
paraoxonase 2.6
ECH 2.5
calcineurin 2.5
5alpha-reductase 2.5
5alpha-reductase 2.5
glyceraldehyde-3-phosphate dehydrogenase 2.5
AMP-activated protein kinase 2.5
phospholipase A2 2.5
ACE 2.4
matrix metalloproteinase 2 2.4
ERK 2.4
urokinase-type plasminogen activator 2.4
CD13 2.4
Thy1 2.3
NOS 2.3
AMPK 2.3
heparinase 2.3
alpha-ketoglutarate dehydrogenase 2.3
NADPH-diaphorase 2.2
peroxiredoxin 2.2
chymase 2.2
sialidase 2.2
cathepsin B 2.1
heme oxygenase 2.1
dopamine beta-hydroxylase 2.1
acyl-CoA dehydrogenase 2.1
6-phosphogluconate dehydrogenase 2.1
glyceraldehyde-3-phosphate dehydrogenase 2.1
more...
Compound
2-Bromoethylamine hydrobromide 11.0
2-Bromoethylamine hydrobromide 11.0
8-Aminoguanine 10.6
8-Bromoadenosine 8.8
8-Bromoadenosine 8.8
8-Bromoadenosine 8.8
8-Bromoadenosine 8.8
8-Bromoadenosine 8.8
8-Bromoadenosine 8.8
8-Bromoadenosine 8.8
Vasopressin 8.7
2-sulfobenzoic acid 8.6
Fludrocortisone acetate 8.6
Trichlormethiazide 8.4
Glycerophosphocholine 8.4
Cytochalasin E 7.9
11,12-EET 7.8
DTMA 7.8
Benzamil 7.7
Amiloride 7.4
hexanamide 7.4
NPPB 7.2
8-HETE 7.0
Biopterin 7.0
aldosterone 7.0
Methazolamide 6.9
Kallidin 6.9
DIDS 6.9
Meclofenamate 6.9
Desmopressin 6.8
Triamterene 6.8
14,15-DHET 6.8
DDMS 6.8
Angiotensin IV 6.8
Monastral Blue 6.8
HCO 6.7
Guanabenz 6.7
Guggulsterone 6.6
Acetazolamide 6.5
NBC 6.5
Diisopropyl fluorophosphate 6.4
Nedaplatin 6.4
Phloretin 6.4
Chelerythrine 6.3
Chelerythrine 6.3
CHIP 6.3
Thiazide 6.2
DTBP 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.2
carbonic acid 6.1
carbonic acid 6.1
carbonic acid 6.1
carbonic acid 6.1
carbonic acid 6.1
carbonic acid 6.1
carbonic acid 6.1
Fenoldopam 6.1
DOCA 6.1
carbonic acid 6.1
3'-AMP 6.1
Lithium chloride 6.1
carbonic acid 6.1
Spironolactone 6.1
Sorbitol 6.0
Luminal 6.0
Jasplakinolide 6.0
Candesartan 6.0
BQ 123 5.9
Oxymetazoline 5.9
TSC 5.9
3,4,5-trimethoxybenzoic acid 5.8
Lithium 5.8
20-HETE 5.8
Combretastatin 5.8
Diamminedichloroplatinum 5.7
carbonic acid 5.7
carbonic acid 5.6
BaCl2 5.6
SHM 5.6
22R-hydroxycholesterol 5.6
PC-2 5.6
M 3 5.4
butyramide 5.4
SITS 5.4
Solu-Medrol 5.3
Inulin 5.3
cAMP 5.3
SDMA 5.3
ethanesulfonic acid 5.3
ethanesulfonic acid 5.3
ETA 5.3
Ouabain 5.3
carbonate 5.3
Hydrochlorothiazide 5.3
DPC 5.3
DPC 5.3
Temsirolimus 5.2
Nystatin 5.2
Kallikrein 5.2
Antimycin 5.2
Nystatin 5.2
Ochratoxin A 5.2
PNA 5.1
D-allose 5.1
Bradykinin 5.1
Heptachlor 5.1
Benzyl alcohol 5.1
urea 5.1
Forskolin 5.0
NEM 5.0
Gb4 5.0
Hoe 4.9
Calcein 4.9
Aspartame 4.9
Cytochalasin D 4.9
PGE2 4.9
UTP 4.9
AICAR 4.9
PGE 4.9
coproporphyrinogen III 4.8
Poly(I:C) 4.8
prostaglandin J2 4.8
Ethacrynic acid 4.8
Phosphoramidon 4.8
Herbimycin 4.8
Foscarnet 4.8
sodium chloride 4.8
PRD 4.8
MAL 4.8
benzenesulfonic acid 4.8
His-Leu 4.8
Sodium 4.7
sodium 4.7
Salix 4.7
cGMP 4.7
methanesulfonamide 4.7
Losartan 4.7
methanesulfonamide 4.7
Neutral Red 4.6
HgCl2 4.6
Nitro-L-arginine 4.6
INN 4.6
SKF 525A 4.6
NPA 4.6
Ang II 4.5
2-methylpiperazine 4.5
S 1 4.5
DETA 4.5
potassium 4.5
MHS 4.5
Thromboxane B2 4.5
Angiotensin II 4.5
more...