Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P41181 (collecting duct)
 5,183 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
collecting duct 5183
vasopressin 865
proximal tubule 552
ATPase 540
aquaporin 436
Sep 324
ENaC 295
water channel 293
arginine vasopressin 287
sodium channel 213
ATP 168
Mol 155
AQP2 145
renin 143
aquaporin 2 142
angiotensin II 103
ROMK 98
AVP 94
insulin 82
mineralocorticoid receptor 77
NDI 77
carbonic anhydrase 75
AQP3 73
pendrin 73
lectin 73
CO2 72
AQP2 protein 71
NKCC2 69
atrial natriuretic peptide 65
anion exchanger 62
AMP 61
bradykinin 59
endoplasmic reticulum 58
brush border 57
nitric oxide synthase 56
PKA 56
AQP1 56
adenylate cyclase 56
adenosinetriphosphatase 55
glycoprotein 54
collagen 54
natriuretic peptide 52
adenylyl cyclase 50
AQP4 50
mm-1 50
atrial natriuretic factor 49
AE1 49
Ang II 46
cyclooxygenase 45
endothelin-1 45
aquaporin-3 43
phosphodiesterase 43
CCD 41
p38 40
ERK 40
ET-1 40
X-linked 40
parathyroid hormone 40
albumin 39
NHE3 39
Gen 39
epidermal growth factor 39
vimentin 38
PKC 38
CHIP28 37
Arginine vasopressin 37
membrane protein 36
ANG 36
MAPK 35
calmodulin 35
Nedd4-2 33
cytokeratin 33
E-cadherin 32
Pendrin 32
cystic fibrosis transmembrane conductance regulator 31
oxytocin 31
ERK1 31
polypeptide 29
fetal kidney 29
glucocorticoid receptor 28
PK1 28
renin receptor 28
ADP 27
aquaporin-4 27
UT-A2 27
ubiquitin 26
EP1 26
GFR 26
Net 26
chloride channel 26
EP4 26
membrane-bound 25
alpha, beta 25
EP3 24
COX-2 24
proton pump 24
kallikrein 24
peroxidase 24
hepatocyte growth factor 24
caspase-3 24
catenin 24
PKD1 23
guanylate cyclase 23
p53 23
collagenase 23
ETB 23
lipopolysaccharide 23
SLC12A3 22
calbindin 22
papillary renal cell carcinoma 22
calcitonin 22
Kir1.1 22
tyrosine kinase 21
ADH 21
SGK1 21
anion exchanger 1 21
HEK 21
chronic renal failure 21
P2Y2 21
cyclooxygenase-2 21
glucagon 21
extracellular signal-regulated kinase 21
TRPV4 20
EP2 20
AT1 20
HSD2 20
microsomal 20
fibronectin 20
MEK 20
dilute 20
ETA 19
aquaporin 4 19
PRR 19
threonine 19
serine protease 19
beta 1 19
cytokine 18
erythroid 18
JNK 18
ANP 18
PKD2 18
Renin 18
PKG 17
adenosine triphosphatase 17
Carbonic anhydrase 17
Rho 17
phosphatase 17
aldose reductase 17
fused 17
ET-3 17
WNK1 16
phosphatidylinositol 3-kinase 16
AVPR2 16
protein tyrosine kinase 16
carbonic anhydrase II 16
PKD 16
SDS 16
angiotensinogen 16
BK channel 16
transporter protein 16
more...
Disease
hypertension 286
nephrogenic diabetes insipidus 194
carcinoma 193
tumor 177
renal cell carcinoma 169
polycystic kidney 142
renal disease 96
dehydration 90
cancer 84
antidiuresis 81
renal failure 73
renal tubular acidosis 68
diabetes insipidus 66
diabetes 64
wasting 55
ureter 52
nephrotic syndrome 48
heart failure 45
congestive heart failure 43
metabolic alkalosis 42
CCD 41
proteinuria 41
cirrhosis 41
CCD 41
metastases 40
Luminal 38
Bellini duct carcinoma 38
hyperosmolality 36
ischemia 35
renal cyst 34
alkalosis 34
pertussis 32
acute renal failure 31
hypercalciuria 30
renal cancer 27
chronic renal failure 27
diabetic nephropathy 26
SEM 26
Bartter's syndrome 26
hypercalcemia 24
Autosomal dominant polycystic kidney disease 22
dysplasia 22
nephrolithiasis 22
WT1 22
ADH 21
ATM 21
adenoma 21
Liddle's syndrome 20
hypernatremia 20
pyelonephritis 18
NAME 17
Autosomal recessive polycystic kidney disease 17
nephrocalcinosis 17
aldosteronism 16
azotemia 16
SDS 16
Congenital nephrogenic diabetes insipidus 15
acute tubular necrosis 15
glomerulosclerosis 15
fluid overload 15
renal insufficiency 14
Hippel 14
carcinogenesis 14
transitional cell carcinoma 14
type 2 diabetes 14
urinary tract obstruction 14
cystic fibrosis 13
NDI 13
deafness 13
hydronephrosis 13
glomerulonephritis 13
PDS 12
epididymis 12
bipolar disorder 12
cold 12
respiratory acidosis 12
renal ischemia 11
urolithiasis 11
genetic disorder 11
Steroids 10
essential hypertension 10
tumorigenesis 10
interstitial nephritis 10
urinary tract infection 10
tuberous sclerosis 10
SCH 10
Evans 10
adenocarcinoma 10
liver disease 9
obesity 9
DBA 9
depression 9
plaque 9
angiomyolipoma 9
hyperparathyroidism 9
Distal renal tubular acidosis 8
Blocking 8
uterus 8
renal papillary necrosis 8
clear cell carcinoma 7
Gitelman syndrome 7
pH increased 7
rare disease 7
nephrosis 7
metastatic renal cell carcinoma 7
uremia 7
nephritis 7
stroke 7
PCT 7
porphyria cutanea tarda 7
NPHP1 7
Brown 7
kidney tumor 7
hyperglycemia 6
hypercholesterolemia 6
preeclampsia 6
cardiovascular disease 6
sepsis 6
sepsis 6
cholera 6
endolymphatic hydrops 6
uropathy 6
MIP 6
Dent's disease 6
sarcoma 6
immaturity 6
cytomegalovirus 5
tubular necrosis 5
benign tumor 5
microalbuminuria 5
sponge kidney 5
potassium deficiency 5
hypothyroidism 5
atherosclerosis 5
type 1 diabetes 5
brain edema 5
EMA 5
epithelial tumor 5
lymphoma 5
HGF 5
hyperinsulinemia 4
aggression 4
PHA 4
goiter 4
PDE 4
melioidosis 4
tetanus 4
ARF 4
neuroblastoma 4
CAM 4
Ureteral obstruction 4
primary tumor 4
hypo-osmolality 4
lymphadenopathy 4
Schmidt 4
renal impairment 4
peritonitis 4
genetic hypertension 4
anemia 4
Pseudohypoaldosteronism 3
more...
Symptom
polyuria 137
polydipsia 40
hypercapnia 6
functional recovery 5
back pain 5
collapse 5
weakness 5
oliguria 4
diarrhea 4
acidity 4
seizures 4
anesthesia 4
fatigue 4
vomiting 4
constipation 3
Macula 3
flank pain 3
anorexia 3
low back pain 3
cough 2
tremor 2
pain 2
dizziness 2
dyspnea 2
lethargy 2
rundown 2
excessive urination 2
flushing 2
tinnitus 1
Decreased activity 1
chest tightness 1
abdominal fullness 1
starvation 1
acute stress 1
Cushingoid 1
hunger 1
male puberty 1
persistent cough 1
abdominal pain 1
exhaustion 1
ketonuria 1
enuresis 1
Cushingoid 1
splenomegaly 1
hypocapnia 1
syncope 1
renal colic 1
respiratory distress 1
headache 1
bitter taste 1
shortness of breath 1
ataxia 1
numbness 1
Drug
Nephron 54
Nephron 48
lysine 46
Amiloride 43
Amiloride 43
NH3 33
Angiotensin II 23
ETA 19
Ouabain 16
Forskolin 14
Cardiovasc 13
Dial 12
DDAVP 12
DDAVP 11
Indomethacin 9
NADH 9
Leaf 9
Ringer's solution 8
Tolvaptan 7
caffeine 7
MAP 6
ICI 5
Sulprostone 5
Glucagon 5
Gel 5
Albumin 5
IFN-gamma 4
Bumetanide 4
CAM 4
citric acid 4
PTH 4
Bosentan 4
Bosentan 4
NAG 4
Asn 4
ROS 3
ETS 3
Aliskiren 3
Monit 3
KGF 3
Hydrochlorothiazide 3
Retinoic acid 3
nitroglycerin 2
Captopril 2
Demeclocycline 2
Clopidogrel 2
Fenoldopam 2
IL-2 2
Sodium nitroprusside 2
DNase I 2
Nitric Oxide 2
Chlorothiazide 2
Growth hormone 2
Ethanol 2
Helium 2
Iloprost 2
EE2 2
Adriamycin 2
Glycerol 2
RPH 2
Growth hormone 2
AmBisome 2
Felodipine 2
Valsartan 2
ABC 2
Estrogens 2
Diamminedichloroplatinum 1
Taxol 1
IL-1ra 1
DOCP 1
niacin 1
MgSO4 1
Adenosine triphosphate 1
CoCl2 1
CoCl2 1
Phosphoramidon 1
Glutathione 1
MRC 1
Urokinase 1
Alanine 1
CTC 1
Carbenoxolone 1
Camostat mesilate 1
EHDP 1
CaCl2 1
Everolimus 1
PFA 1
DPA 1
Butaprost 1
Parecoxib 1
Plavix 1
lactose 1
Fluorescein 1
KCL 1
Pitressin 1
Propofol 1
Aprotinin 1
Biopolymers 1
CDP 1
Monensin 1
Rolipram 1
Vena 1
Vena 1
Roflumilast 1
CTX 1
THF 1
Hyaluronidase 1
CaCl2 1
Viagra 1
CaCl2 1
Piretanide 1
Fructose 1
uPA 1
Histamine 1
MDM 1
Atropine 1
CTC 1
Micardis 1
CTX 1
Imidafenacin 1
AC2 1
Olmesartan 1
PTC 1
Secretin 1
Troglitazone 1
Paraffin 1
Roflumilast 1
Viagra 1
ALA 1
CTX 1
Nafamostat mesilate 1
Heme 1
Erlotinib 1
Torasemide 1
CTA 1
G418 1
Activin 1
Fluorescein 1
Hyaluronidase 1
IFN-beta 1
R1881 1
Glycyrrhiza 1
Adenosine deaminase 1
Atipamezole 1
Diphenhydramine 1
Enzyme
ATPase 573
protein kinase 215
renin 143
protein kinase C 134
mitogen-activated protein kinase 104
ERK 81
carbonic anhydrase 74
luciferase 58
adenylate cyclase 57
phospholipase C 44
phosphodiesterase 43
NO synthase 36
guanylate cyclase 35
peroxidase 30
MEK 25
kallikrein 24
collagenase 24
RNase 22
RNase 22
glutathione S-transferase 22
ADH 21
reverse transcriptase 21
alcohol dehydrogenase 21
11beta-hydroxysteroid dehydrogenase 20
caspase-3 19
PKG 17
aldose reductase 17
trypsin 16
phosphatidylinositol 3-kinase 16
CD10 16
ACE 16
calcineurin 16
H,K-ATPase 15
proteasome 13
RNA polymerase 13
NADPH oxidase 13
plasmin 13
NADPH oxidase 13
phospholipase A2 13
alkaline phosphatase 12
prostasin 12
AMP-activated protein kinase 12
ribonuclease 11
ribonuclease 11
DCF 11
AMPK 10
ubiquitin-protein ligase 10
HSD 10
transcriptase 10
CPT 9
focal adhesion kinase 9
CPT 9
CPT 9
gamma-glutamyl transpeptidase 9
urokinase-type plasminogen activator 9
pyruvate kinase 9
beta-galactosidase 9
GSK 8
furin 8
succinate dehydrogenase 8
fumarase 8
ATP synthase 8
tissue kallikrein 7
hyaluronidase 7
cathepsin D 7
phosphoinositide 3-kinase 7
hyaluronidase 7
cGMP phosphodiesterase 7
glutamine synthetase 7
phosphoenolpyruvate carboxykinase 6
phosphoenolpyruvate carboxykinase 6
malate dehydrogenase 6
sorbitol dehydrogenase 6
glyceraldehyde-3-phosphate dehydrogenase 6
PDE 6
MIP 6
NOS 6
phosphoenolpyruvate carboxykinase 6
MAP 5
xanthine oxidase 5
superoxide dismutase 5
citrate synthase 5
myosin light chain kinase 5
lactate dehydrogenase 5
CaMKII 4
caspase-1 4
AMPK 4
protein phosphatase 2A 4
AMP-activated kinase 4
arginase 4
neuraminidase 4
P-glycoprotein 4
glutaminase 3
cathepsin B 3
IKK 3
glyceraldehyde-3-phosphate dehydrogenase 3
CD13 3
hexokinase 3
glyceraldehyde-3-phosphate dehydrogenase 3
apyrase 3
caspase-7 3
lipoxygenase 3
endoglycosidase H 3
heme oxygenase 3
chymotrypsin 3
prolyl hydroxylase 3
urease 3
ornithine aminotransferase 3
site-1 protease 3
acid phosphatase 3
urease 3
glyceraldehyde-3-phosphate dehydrogenase 3
site-1 protease 3
purine nucleoside phosphorylase 3
caspase-7 3
NADPH-diaphorase 3
glyceraldehyde-3-phosphate dehydrogenase 3
PARP 2
catalase 2
TdT 2
glucose oxidase 2
RPH 2
cathepsin K 2
angiotensin-converting enzyme 2 2
sialidase 2
neuropathy target esterase 2
caspase-9 2
CAD 2
cytochrome oxidase 2
matrix metalloproteinase 2 2
thrombin 2
5'-nucleotidase 2
kinesin 2
hexosaminidase 2
prostaglandin synthetase 2
diaphorase 2
glucose-6-phosphate dehydrogenase 2
aldolase 2
HK2 2
15-hydroxyprostaglandin dehydrogenase 2
proton-translocating ATPase 2
complex I 2
glucose-6-phosphatase 2
endonuclease 2
pepsin 2
DNase 2
PST 2
phospholipase D 2
adenosine deaminase 2
1-hydroxylase 2
lysozyme 2
adenosine deaminase 2
peroxiredoxin 2
CAD 2
CAD 2
paraoxonase 2
isopeptidase 1
uridine phosphorylase 1
elastase 1
monoamine oxidase 1
more...
Compound
water 1332
sodium 1202
aldosterone 500
cAMP 384
Dec 375
calcium 371
potassium 350
urea 347
salt 340
Clin 311
carbonate 186
ATP 168
Vasopressin 154
DNA 121
arginine 114
ammonium 98
ammonia 96
glucose 94
HCO 92
phosphate 90
cGMP 89
nitric oxide 89
CO2 87
hydrogen 82
creatinine 77
NH2 75
serine 72
PGE2 71
acetate 69
AMP 65
oxygen 60
lysine 55
sodium chloride 51
tyrosine 50
Amiloride 43
Lithium 43
PGE 42
Sodium 41
Luminal 39
alanine 34
oxalate 34
Angiotensin II 32
threonine 31
glycerol 31
galactose 31
DIDS 31
nitrogen 30
ADP 30
sulfate 29
ADP 28
ADP 27
Ang II 26
UTP 23
proline 22
Mg2+ 22
DOCA 22
methionine 21
leucine 21
alcohol dehydrogenase 21
MEK 19
ETA 19
vitamin D 18
NPPB 18
barium 18
GMP 17
SDS 17
Salix 17
His 16
Ouabain 16
mercury 16
Insulin 15
bromide 15
GTP 15
cysteine 15
Dopamine 14
betaine 14
Forskolin 14
PNA 14
HCl 14
NAD 14
benzoic acid 14
Asp 13
Acetazolamide 13
nitrate 12
prostacyclin 12
H2O2 12
chlorine 12
Bradykinin 12
glutamine 12
manganese 12
CHIP 11
Dial 11
iron 11
cadmium 11
Dexamethasone 11
zinc 10
Adenosine 10
NAD 10
PMA 10
HgCl2 9
NADPH 9
CPT 9
DBA 9
iodine 9
retinoic acid 9
Phe 9
acetamide 9
carbonic acid 9
DBA 9
DBA 9
NADH 9
silver 9
acetamide 9
NADPH 9
NADP 9
adenylate 9
CPT 9
formaldehyde 9
Salt 9
Triton X-100 9
Indomethacin 8
Sorbitol 8
PMA 8
11,12-EET 8
2-hydroxyethyl 8
Spironolactone 8
carbonic acid 7
carbonic acid 7
noradrenaline 7
carbonic acid 7
phosphorus 7
ethanol 7
Oxytocin 7
TNM 7
carbonic acid 7
tryptophan 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
rubidium 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
Desmopressin 7
carbonic acid 7
COX 7
carbonic acid 7
carbonic acid 7
carbonic acid 7
SCN 7
thiourea 7
DCC 7
caffeine 7
MAP 6
pyrimidine 6
more...