Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P41181 (collecting duct)
 5,183 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Renal coccidiosis is reported for the first time in an auk (Alcidae). Infection was detected in seven of 50 nestling Atlantic puffins (Fratercula arctica) and a new species of coccidia, Eimeria fraterculae sp. n., is described. The structure and sporulation of oocysts are characterized. Meronts, gamonts, and developing oocysts were present in collecting duct epithelium of medullary cones. The predominant host response was hypertrophy of infected cells, tubule dilation, and a mild localized peritubular infiltration with mononuclear inflammatory cells.
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PMID:Eimeria fraterculae sp. n. in the kidneys of Atlantic puffins (Fratercula arctica) from Newfoundland, Canada: species description and lesions. 350 38

We diagnosed renal coccidiosis in two of five Great-horned Owls ( Bubo virginianus ) examined in eastern Tennessee, US, 2007-13. Histopathologic examination of the kidneys revealed multifocal mild-to-moderate dilation and epithelial hyperplasia of collecting ducts. Renal collecting duct epithelial cells contained intracytoplasmic microgametocytes, macrogametocytes, and sporulating and sporulated oocysts. Renal coccidiosis in affected birds did not result in significant inflammation. Sequence analysis of the amplified partial 18S short subunit ribosomal RNA coding region from examination of formalin fixed tissue by using PCR disclosed a 93% identity to Eimeria reichenowi in GenBank, suggesting a novel Eimeria sp.
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PMID:Identification of a Novel Renal Coccidian (Apicomplexa: Eimeriidae) from the Great-Horned Owl ( Bubo virginianus ), USA. 2813 53