Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P39060 (endostatin)
2,284 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
endostatin 2284
vascular endothelial growth factor 365
Endostatin 312
Sep 168
VEGF 152
collagen 144
Mol 132
thrombospondin 77
matrix metalloproteinase 46
CD31 42
perlecan 40
tyrosine kinase 40
VEGFR2 37
MMP-9 36
cytokine 33
MMP-2 32
Vascular endothelial growth factor 30
proteoglycan 28
endogenous angiogenesis inhibitor 26
p53 25
fibronectin 24
angiogenin 24
vascular endothelial growth factor receptor 24
NMR 23
plasminogen 23
polypeptide 22
agrin 22
caspase-3 22
TMN 22
epidermal growth factor receptor 22
COL18A1 21
mTOR 20
platelet-derived growth factor 20
vascular endothelial growth factor A 19
bFGF 19
platelet-derived 19
tumor necrosis factor 19
FGF 19
ACS 18
ATP 18
vascular endothelial growth factor receptor 2 17
hepatocyte growth factor 17
KDR 16
Plasmin 16
vascular endothelium 15
angiopoietin-1 15
endoglin 15
ATPase 14
FGF-2 14
SDS 14
p38 14
nitric oxide synthase 14
pigment epithelium-derived factor 14
PEG 14
interferon 14
PDGF 14
CD34 14
MRI 13
ERK1 13
VEGFR-1 13
frizzled 13
HPO 12
ERK 12
hemoglobin 12
type XV collagen 12
placental growth factor 12
angiopoietin-2 12
NADH 11
receptor tyrosine kinase 11
fused 11
restin 11
osteopontin 11
Pseudomonas 11
metalloproteinase 11
TNF 10
TIMP-2 10
cage 10
nucleolin 10
colon carcinoma 10
glutamine synthetase 10
more...
Disease
KNO 634
tumor 604
cancer 574
tumor growth 316
tumor angiogenesis 99
metastases 72
breast cancer 71
tumor progression 63
carcinoma 60
lung cancer 53
hepatocellular carcinoma 52
lung carcinoma 45
colorectal cancer 41
non-small cell lung cancer 39
glioma 36
prostate cancer 35
tumor vasculature 34
melanoma 32
hypertension 32
renal cell carcinoma 27
adenocarcinoma 27
glioblastoma 27
colon cancer 27
diabetes 26
primary tumor 25
ovarian cancer 25
squamous cell carcinoma 23
rheumatoid arthritis 21
gastric cancer 20
macular degeneration 20
carcinogenesis 18
tumorigenesis 18
diabetic retinopathy 18
liver cancer 18
ischemia 18
arthritis 17
multiple myeloma 16
stroke 16
cornea 15
lung metastases 14
PSS 14
solid tumor 14
SDS 14
heart failure 13
glioblastoma multiforme 13
liver cancer 13
atherosclerosis 13
leukemia 13
pancreatic cancer 12
SCID 12
acute myeloid leukemia 12
mole 12
mole 12
Alzheimer's disease 11
proteinuria 11
epithelial ovarian cancer 11
neutropenia 11
MCF 11
obesity 11
brain tumor 11
metastatic breast cancer 10
brain metastases 10
myocardial infarction 10
Hepatocellular carcinoma 9
TEM 9
coronary artery disease 9
blindness 9
TEM 9
osteosarcoma 9
liver metastases 9
mammary tumor 8
neuroblastoma 8
vitreoretinal degeneration 8
cervical cancer 8
cardiovascular disease 8
metastatic renal cell carcinoma 8
endometriosis 8
anemia 8
sarcoma 7
mimicry 7
more...
Symptom
diarrhea 12
fatigue 10
pain 9
nausea 7
starvation 6
vomiting 6
acidity 5
hemoptysis 4
agitation 4
overweight 4
collapse 4
hyperoxia 3
constipation 3
tremor 3
headache 3
nausea and vomiting 3
chest pain 3
thinning 3
cough 2
anorexia 2
weakness 2
functional recovery 2
anesthesia 2
cyanosis 1
Halo 1
atypical chest pain 1
sleepiness 1
dysarthria 1
dyspnea 1
discomfort 1
dry eye 1
lethargy 1
flushing 1
abdominal cramps 1
discomfort 1
insomnia 1
microbial colonization 1
Continuous leakage 1
Wind 1
hypotonia 1
hypoproteinemia 1
respiratory distress 1
hepatosplenomegaly 1
asthenia 1
seizures 1
numbness 1
hoarseness 1
ataxia 1
rigors 1
Drug
Bevacizumab 48
NADH 11
lysine 11
CTX 10
ascorbate 8
Bifidobacterium 7
CTX 7
CTX 7
citric acid 6
Leaf 6
CAM 5
vitamin E 5
Monit 4
Everolimus 4
Cetuximab 4
Sorafenib 4
Dermatol 4
ROC 4
NaI 3
IL-2 3
NaI 3
Alanine 3
Gel 3
IFN-gamma 3
uPA 3
NaI 3
KGF 3
Docetaxel 3
MAP 3
CSF 3
NaI 3
Nephron 2
LMWH 2
Cardiovasc 2
Sensodyne 2
Nitric Oxide 2
CTT 2
Etoposide 2
Gentian violet 2
CoCl2 2
TES 2
CoCl2 2
Fragment 2
Itraconazole 2
IL-1ra 2
TAC 2
Adriamycin 2
ROS 2
RbCl 2
Erlotinib 2
ABC 2
RbCl 2
PZC 2
Spectrum 2
EHDP 2
DPA 2
Doyle 1
ampicillin 1
MOF 1
Proleukin 1
Hyperforin 1
Xanthium 1
Talc 1
Magnesium phosphate 1
Zoledronic acid 1
Sunitinib malate 1
EPI 1
Gefitinib 1
Gelatin 1
Rituximab 1
NOV 1
Arsenic trioxide 1
AMC 1
Orphan 1
GEO 1
Axitinib 1
Ranitidine 1
Navelbine 1
Herceptin 1
Asn 1
more...
Enzyme
ERK 69
mitogen-activated protein kinase 32
nitrate reductase 31
nitrate reductase 29
nitrate reductase 29
nitrate reductase 29
nitrate reductase 29
nitrate reductase 29
caspase-3 20
ACS 18
collagenase 17
focal adhesion kinase 16
ATPase 15
luciferase 15
urokinase-type plasminogen activator 12
protein kinase 12
NO synthase 12
MMP 10
glutamine synthetase 10
plasmin 9
proteasome 9
peroxidase 9
TSP-1 9
alkaline phosphatase 8
cathepsin L 8
protein kinase C 7
nitrogenase 7
PARP 6
trypsin 6
thrombin 6
nitrite reductase 5
nitrite reductase 5
nitrite reductase 5
caspase-9 5
NADPH oxidase 5
phosphatidylinositol 3-kinase 5
MAP 5
MMP-3 5
cytosine deaminase 5
tissue plasminogen activator 5
MEK 4
catalase 4
caspase-8 4
NOS 4
lactate dehydrogenase 4
glutathione S-transferase 4
elastase 4
cdc2 4
lipase 4
RNase 4
glutathione reductase 4
superoxide dismutase 4
hyaluronidase 3
guanylate cyclase 3
sucrose synthase 3
reverse transcriptase 3
ribonuclease 3
RNase 3
ACE 3
cathepsin B 3
chymotrypsin 3
ribonuclease 3
phosphoenolpyruvate carboxylase 3
ceruloplasmin 3
lysyl oxidase 3
heparinase 3
SMP 2
carbonic anhydrase 2
isocitrate dehydrogenase 2
isocitrate dehydrogenase 2
aspartate aminotransferase 2
diaphorase 2
calcineurin 2
NADPH oxidase 2
prostate-specific antigen 2
topoisomerase 2
xylanase 2
renin 2
beta-galactosidase 2
kallikrein 2
more...
Compound
nitrate 161
Dec 152
water 127
nitrogen 125
Clin 89
oxygen 87
potassium 86
salt 72
sulfate 71
DNA 61
nitric oxide 51
copper 49
sodium 46
phosphate 44
ammonium 39
glucose 39
zinc 38
arginine 33
Collagen 32
urea 30
calcium 29
hydrogen 27
MTT 27
Gly 26
EDTA 20
EDTA 20
acetate 20
alanine 20
Nitrate 19
iron 19
Cu(II) 18
ATP 18
ACS 18
ACS 18
PEG 17
tyrosine 17
PEG 17
NH2 17
cysteine 16
silver 15
ethanol 15
His 15
HCl 14
galactose 14
SDS 14
Asp 13
cadmium 13
nickel 13
MDA 13
glycerol 12
ADP 12
Neo 12
lysine 11
KOH 11
NADH 11
ammonia 11
CTX 10
serine 10
TNF 10
iodine 10
bromide 10
TEM 10
acetic acid 10
ClO 9
Heparan sulfate 9
proline 9
mercury 9
CO2 9
ADP 8
pyridine 8
hydroxide 8
ADP 8
leucine 8
glutamine 7
methanol 7
methionine 7
chromium 7
creatinine 7
ASA 7
manganese 7
more...