Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P39060 (
endostatin
)
2,284
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
endostatin
2284
vascular endothelial growth factor
365
Endostatin
312
Sep
168
VEGF
152
collagen
144
Mol
132
thrombospondin
77
matrix metalloproteinase
46
CD31
42
perlecan
40
tyrosine kinase
40
VEGFR2
37
MMP-9
36
cytokine
33
MMP-2
32
Vascular endothelial growth factor
30
proteoglycan
28
endogenous angiogenesis inhibitor
26
p53
25
fibronectin
24
angiogenin
24
vascular endothelial growth factor receptor
24
NMR
23
plasminogen
23
polypeptide
22
agrin
22
caspase-3
22
TMN
22
epidermal growth factor receptor
22
COL18A1
21
mTOR
20
platelet-derived growth factor
20
vascular endothelial growth factor A
19
bFGF
19
platelet-derived
19
tumor necrosis factor
19
FGF
19
ACS
18
ATP
18
vascular endothelial growth factor receptor 2
17
hepatocyte growth factor
17
KDR
16
Plasmin
16
vascular endothelium
15
angiopoietin-1
15
endoglin
15
ATPase
14
FGF-2
14
SDS
14
p38
14
nitric oxide synthase
14
pigment epithelium-derived factor
14
PEG
14
interferon
14
PDGF
14
CD34
14
MRI
13
ERK1
13
VEGFR-1
13
frizzled
13
HPO
12
ERK
12
hemoglobin
12
type XV collagen
12
placental growth factor
12
angiopoietin-2
12
NADH
11
receptor tyrosine kinase
11
fused
11
restin
11
osteopontin
11
Pseudomonas
11
metalloproteinase
11
TNF
10
TIMP-2
10
cage
10
nucleolin
10
colon carcinoma
10
glutamine synthetase
10
more...
Disease
KNO
634
tumor
604
cancer
574
tumor growth
316
tumor angiogenesis
99
metastases
72
breast cancer
71
tumor progression
63
carcinoma
60
lung cancer
53
hepatocellular carcinoma
52
lung carcinoma
45
colorectal cancer
41
non-small cell lung cancer
39
glioma
36
prostate cancer
35
tumor vasculature
34
melanoma
32
hypertension
32
renal cell carcinoma
27
adenocarcinoma
27
glioblastoma
27
colon cancer
27
diabetes
26
primary tumor
25
ovarian cancer
25
squamous cell carcinoma
23
rheumatoid arthritis
21
gastric cancer
20
macular degeneration
20
carcinogenesis
18
tumorigenesis
18
diabetic retinopathy
18
liver cancer
18
ischemia
18
arthritis
17
multiple myeloma
16
stroke
16
cornea
15
lung metastases
14
PSS
14
solid tumor
14
SDS
14
heart failure
13
glioblastoma multiforme
13
liver cancer
13
atherosclerosis
13
leukemia
13
pancreatic cancer
12
SCID
12
acute myeloid leukemia
12
mole
12
mole
12
Alzheimer's disease
11
proteinuria
11
epithelial ovarian cancer
11
neutropenia
11
MCF
11
obesity
11
brain tumor
11
metastatic breast cancer
10
brain metastases
10
myocardial infarction
10
Hepatocellular carcinoma
9
TEM
9
coronary artery disease
9
blindness
9
TEM
9
osteosarcoma
9
liver metastases
9
mammary tumor
8
neuroblastoma
8
vitreoretinal degeneration
8
cervical cancer
8
cardiovascular disease
8
metastatic renal cell carcinoma
8
endometriosis
8
anemia
8
sarcoma
7
mimicry
7
more...
Symptom
diarrhea
12
fatigue
10
pain
9
nausea
7
starvation
6
vomiting
6
acidity
5
hemoptysis
4
agitation
4
overweight
4
collapse
4
hyperoxia
3
constipation
3
tremor
3
headache
3
nausea and vomiting
3
chest pain
3
thinning
3
cough
2
anorexia
2
weakness
2
functional recovery
2
anesthesia
2
cyanosis
1
Halo
1
atypical chest pain
1
sleepiness
1
dysarthria
1
dyspnea
1
discomfort
1
dry eye
1
lethargy
1
flushing
1
abdominal cramps
1
discomfort
1
insomnia
1
microbial colonization
1
Continuous leakage
1
Wind
1
hypotonia
1
hypoproteinemia
1
respiratory distress
1
hepatosplenomegaly
1
asthenia
1
seizures
1
numbness
1
hoarseness
1
ataxia
1
rigors
1
Drug
Bevacizumab
48
NADH
11
lysine
11
CTX
10
ascorbate
8
Bifidobacterium
7
CTX
7
CTX
7
citric acid
6
Leaf
6
CAM
5
vitamin E
5
Monit
4
Everolimus
4
Cetuximab
4
Sorafenib
4
Dermatol
4
ROC
4
NaI
3
IL-2
3
NaI
3
Alanine
3
Gel
3
IFN-gamma
3
uPA
3
NaI
3
KGF
3
Docetaxel
3
MAP
3
CSF
3
NaI
3
Nephron
2
LMWH
2
Cardiovasc
2
Sensodyne
2
Nitric Oxide
2
CTT
2
Etoposide
2
Gentian violet
2
CoCl2
2
TES
2
CoCl2
2
Fragment
2
Itraconazole
2
IL-1ra
2
TAC
2
Adriamycin
2
ROS
2
RbCl
2
Erlotinib
2
ABC
2
RbCl
2
PZC
2
Spectrum
2
EHDP
2
DPA
2
Doyle
1
ampicillin
1
MOF
1
Proleukin
1
Hyperforin
1
Xanthium
1
Talc
1
Magnesium phosphate
1
Zoledronic acid
1
Sunitinib malate
1
EPI
1
Gefitinib
1
Gelatin
1
Rituximab
1
NOV
1
Arsenic trioxide
1
AMC
1
Orphan
1
GEO
1
Axitinib
1
Ranitidine
1
Navelbine
1
Herceptin
1
Asn
1
more...
Enzyme
ERK
69
mitogen-activated protein kinase
32
nitrate reductase
31
nitrate reductase
29
nitrate reductase
29
nitrate reductase
29
nitrate reductase
29
nitrate reductase
29
caspase-3
20
ACS
18
collagenase
17
focal adhesion kinase
16
ATPase
15
luciferase
15
urokinase-type plasminogen activator
12
protein kinase
12
NO synthase
12
MMP
10
glutamine synthetase
10
plasmin
9
proteasome
9
peroxidase
9
TSP-1
9
alkaline phosphatase
8
cathepsin L
8
protein kinase C
7
nitrogenase
7
PARP
6
trypsin
6
thrombin
6
nitrite reductase
5
nitrite reductase
5
nitrite reductase
5
caspase-9
5
NADPH oxidase
5
phosphatidylinositol 3-kinase
5
MAP
5
MMP-3
5
cytosine deaminase
5
tissue plasminogen activator
5
MEK
4
catalase
4
caspase-8
4
NOS
4
lactate dehydrogenase
4
glutathione S-transferase
4
elastase
4
cdc2
4
lipase
4
RNase
4
glutathione reductase
4
superoxide dismutase
4
hyaluronidase
3
guanylate cyclase
3
sucrose synthase
3
reverse transcriptase
3
ribonuclease
3
RNase
3
ACE
3
cathepsin B
3
chymotrypsin
3
ribonuclease
3
phosphoenolpyruvate carboxylase
3
ceruloplasmin
3
lysyl oxidase
3
heparinase
3
SMP
2
carbonic anhydrase
2
isocitrate dehydrogenase
2
isocitrate dehydrogenase
2
aspartate aminotransferase
2
diaphorase
2
calcineurin
2
NADPH oxidase
2
prostate-specific antigen
2
topoisomerase
2
xylanase
2
renin
2
beta-galactosidase
2
kallikrein
2
more...
Compound
nitrate
161
Dec
152
water
127
nitrogen
125
Clin
89
oxygen
87
potassium
86
salt
72
sulfate
71
DNA
61
nitric oxide
51
copper
49
sodium
46
phosphate
44
ammonium
39
glucose
39
zinc
38
arginine
33
Collagen
32
urea
30
calcium
29
hydrogen
27
MTT
27
Gly
26
EDTA
20
EDTA
20
acetate
20
alanine
20
Nitrate
19
iron
19
Cu(II)
18
ATP
18
ACS
18
ACS
18
PEG
17
tyrosine
17
PEG
17
NH2
17
cysteine
16
silver
15
ethanol
15
His
15
HCl
14
galactose
14
SDS
14
Asp
13
cadmium
13
nickel
13
MDA
13
glycerol
12
ADP
12
Neo
12
lysine
11
KOH
11
NADH
11
ammonia
11
CTX
10
serine
10
TNF
10
iodine
10
bromide
10
TEM
10
acetic acid
10
ClO
9
Heparan sulfate
9
proline
9
mercury
9
CO2
9
ADP
8
pyridine
8
hydroxide
8
ADP
8
leucine
8
glutamine
7
methanol
7
methionine
7
chromium
7
creatinine
7
ASA
7
manganese
7
more...