Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P39060 (endostatin)
2,284 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
endostatin 2284
vascular endothelial growth factor 365
Endostatin 312
Sep 168
VEGF 152
collagen 144
Mol 132
thrombospondin 77
matrix metalloproteinase 46
CD31 42
perlecan 40
tyrosine kinase 40
VEGFR2 37
MMP-9 36
cytokine 33
MMP-2 32
Vascular endothelial growth factor 30
proteoglycan 28
endogenous angiogenesis inhibitor 26
p53 25
angiogenin 24
vascular endothelial growth factor receptor 24
fibronectin 24
plasminogen 23
NMR 23
agrin 22
epidermal growth factor receptor 22
polypeptide 22
caspase-3 22
TMN 22
COL18A1 21
mTOR 20
platelet-derived growth factor 20
bFGF 19
tumor necrosis factor 19
vascular endothelial growth factor A 19
platelet-derived 19
FGF 19
ATP 18
ACS 18
more...
Disease
KNO 634
tumor 604
cancer 574
tumor growth 316
tumor angiogenesis 99
metastases 72
breast cancer 71
tumor progression 63
carcinoma 60
lung cancer 53
hepatocellular carcinoma 52
lung carcinoma 45
colorectal cancer 41
non-small cell lung cancer 39
glioma 36
prostate cancer 35
tumor vasculature 34
hypertension 32
melanoma 32
adenocarcinoma 27
renal cell carcinoma 27
colon cancer 27
glioblastoma 27
diabetes 26
primary tumor 25
ovarian cancer 25
squamous cell carcinoma 23
rheumatoid arthritis 21
macular degeneration 20
gastric cancer 20
ischemia 18
carcinogenesis 18
diabetic retinopathy 18
tumorigenesis 18
liver cancer 18
arthritis 17
multiple myeloma 16
stroke 16
cornea 15
SDS 14
more...
Symptom
diarrhea 12
fatigue 10
pain 9
nausea 7
starvation 6
vomiting 6
acidity 5
hemoptysis 4
collapse 4
agitation 4
overweight 4
hyperoxia 3
constipation 3
tremor 3
chest pain 3
nausea and vomiting 3
headache 3
thinning 3
cough 2
anorexia 2
weakness 2
functional recovery 2
anesthesia 2
cyanosis 1
Halo 1
atypical chest pain 1
sleepiness 1
dysarthria 1
discomfort 1
abdominal cramps 1
discomfort 1
hypotonia 1
insomnia 1
dry eye 1
lethargy 1
hypoproteinemia 1
respiratory distress 1
hepatosplenomegaly 1
asthenia 1
numbness 1
more...
Drug
Bevacizumab 48
lysine 11
NADH 11
CTX 10
ascorbate 8
Bifidobacterium 7
CTX 7
CTX 7
Leaf 6
citric acid 6
CAM 5
vitamin E 5
Monit 4
Everolimus 4
Sorafenib 4
Cetuximab 4
Dermatol 4
ROC 4
Alanine 3
NaI 3
Gel 3
KGF 3
IFN-gamma 3
CSF 3
uPA 3
NaI 3
Docetaxel 3
NaI 3
NaI 3
IL-2 3
MAP 3
Nephron 2
Cardiovasc 2
LMWH 2
Sensodyne 2
DPA 2
Nitric Oxide 2
PZC 2
Gentian violet 2
EHDP 2
more...
Enzyme
ERK 69
mitogen-activated protein kinase 32
nitrate reductase 31
nitrate reductase 29
nitrate reductase 29
nitrate reductase 29
nitrate reductase 29
nitrate reductase 29
caspase-3 20
ACS 18
collagenase 17
focal adhesion kinase 16
ATPase 15
luciferase 15
urokinase-type plasminogen activator 12
NO synthase 12
protein kinase 12
glutamine synthetase 10
MMP 10
TSP-1 9
proteasome 9
plasmin 9
peroxidase 9
alkaline phosphatase 8
cathepsin L 8
nitrogenase 7
protein kinase C 7
PARP 6
thrombin 6
trypsin 6
nitrite reductase 5
tissue plasminogen activator 5
MAP 5
MMP-3 5
nitrite reductase 5
nitrite reductase 5
NADPH oxidase 5
phosphatidylinositol 3-kinase 5
caspase-9 5
cytosine deaminase 5
more...
Compound
nitrate 161
Dec 152
water 127
nitrogen 125
Clin 89
oxygen 87
potassium 86
salt 72
sulfate 71
DNA 61
nitric oxide 51
copper 49
sodium 46
phosphate 44
ammonium 39
glucose 39
zinc 38
arginine 33
Collagen 32
urea 30
calcium 29
hydrogen 27
MTT 27
Gly 26
EDTA 20
EDTA 20
acetate 20
alanine 20
iron 19
Nitrate 19
ACS 18
ACS 18
Cu(II) 18
ATP 18
tyrosine 17
PEG 17
NH2 17
PEG 17
cysteine 16
ethanol 15
more...