Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P39060 (endostatin)
 2,284 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
endostatin 13.8
pigment epithelial-differentiating factor 13.8
Endostatin 13.5
P4HA2 protein 12.8
COL18A1 12.0
restin 11.8
METH-2 11.8
endogenous angiogenesis inhibitor 11.7
type IV collagen alpha3 chain 11.4
type XV collagen 11.4
FADS6 11.2
G protein-coupled receptor 124 11.2
canstatin 10.9
bamacan 10.7
carboxypeptidase Z 10.6
PR48 10.4
MYO1D 10.4
Rab11-FIP4 10.3
FGF-13 10.3
AMACO 10.3
PTP4A2 10.3
arresten 10.2
frizzled 1 10.1
INCLUDED 10.0
Ephrin-B3 10.0
TMN 9.9
matrix metalloproteinase 11 9.9
DOC1 9.7
plasminogen-like protein 9.6
PTPsigma 9.6
lipophilin B 9.5
NG3 9.4
fibulin-2 9.4
Tissue inhibitor of metalloproteinase 1 9.4
opticin 9.3
P125 9.3
COL14A1 9.2
BAVM 9.2
BCL-G 9.2
NP-I 9.2
nidogen-2 9.1
LCA2 9.1
allele c 9.1
metargidin 9.0
GPR124 9.0
ANGPTL1 9.0
PCPE-1 9.0
PEDF 8.9
NAC-1 8.9
perlecan 8.9
pigment epithelium-derived factor 8.8
chondromodulin-I 8.8
mTERF 8.8
UNC119 8.8
ENDO 8.7
fibulin-1 8.7
cathepsin V 8.6
CXCL4L1 8.6
Angiopoietin 2 8.6
PTPRK 8.5
gravin 8.5
FREM2 8.5
ADAMTS20 8.4
ME3 8.4
type XIX collagen 8.4
C-X-C motif chemokine 5 8.3
RPS7 8.3
agrin 8.3
angiogenin 8.3
DOCK4 8.3
endomucin 8.2
UTF1 8.2
endocan 8.1
PZP 8.1
ATP1B1 8.1
Ror1 8.1
carcinoembryonic antigen-related cell adhesion molecule 8.1
thrombospondin 8.0
frizzled 8.0
Down syndrome candidate region 1 8.0
angiopoietin-2 8.0
FRAS1 8.0
adenomatous polyposis coli protein 7.9
ULBP3 7.9
EGFL7 7.9
hyaluronan binding protein 7.9
VEGFB 7.9
Plasmin 7.8
thrombospondin 1 7.8
Pigment epithelium-derived factor 7.8
glutamate dehydrogenase 1 7.8
transient receptor potential melastatin 6 7.8
GDH2 7.8
deoxynucleotidyltransferase 7.7
HUB 7.7
Angiopoietin-2 7.7
fibulin-4 7.7
SUT 7.7
FZD8 7.7
FUT6 7.6
PAR4 7.6
endoglin 7.6
CgA 7.6
insulin-like growth factor binding protein 7 7.6
FAR1 7.6
ATG9A 7.6
KRT1 7.6
vascular endothelial growth factor receptor 2 7.6
Platelet factor 4 7.6
asporin 7.6
TAPS 7.5
TTG1 7.5
ESM-1 7.5
E1B19K 7.5
BMP10 7.5
BAI1 7.5
EGP 7.5
CTP synthase 7.5
ISG20 7.5
DNA polymerase lambda 7.5
ORP150 7.5
HE1 7.5
ephrin-B3 7.5
of 300 kDa 7.4
AHSG 7.4
anion exchange protein 7.4
angiopoietin-1 7.4
PSP94 7.4
Cathepsin L 7.4
VAMP-8 7.4
PG-M 7.4
AKAP12 7.4
vascular endothelial growth factor 7.4
hES 7.4
GPAT 7.3
PLGF 7.2
LH3 7.2
Cav3.3 7.2
P66 7.2
nidogen 7.2
3-phosphoinositide-dependent protein kinase 1 7.2
HSP-60 7.2
C1qR 7.2
syntaxin 6 7.2
methionine aminopeptidase 7.2
CSE1L 7.2
GIPC 7.2
RGS5 7.2
protease-activated receptor 4 7.2
tissue inhibitor of metalloproteinase-3 7.1
TEM8 7.1
alpha S1-casein 7.1
A121 7.1
ADAM33 7.1
ZIP4 7.1
TE2 7.1
metallocarboxypeptidase 7.1
saccharopine dehydrogenase 7.0
KDR 7.0
VEGF 7.0
more...
Disease
KNO 13.8
KNO2 10.8
vitreoretinal degeneration 10.6
Metastatic Prostate Cancer 10.2
Funisitis 10.0
Neovascular age-related macular degeneration 8.7
Primary intestinal lymphangiectasia 8.7
androgen independent prostate cancer 7.9
tumor angiogenesis 7.8
Blackleg 7.7
cancer angiogenesis 7.6
tumor vasculature 7.6
DA3 7.4
Lewis Lung Carcinoma 7.1
Microangiopathy 7.1
recurrent NSCLC 7.0
NNH 7.0
recurrent ovarian cancer 6.9
eye cancer 6.8
hand-foot syndrome 6.7
metastatic cervical cancer 6.6
recurrent cervical cancer 6.6
malignant ascites 6.6
CLE 6.5
CLE 6.4
tumor growth 6.2
TCO 6.1
bone neoplasm 5.9
cherubism 5.8
hemangiosarcoma 5.7
hemangioendothelioma 5.7
GS1 5.7
metastatic neuroblastoma 5.7
local cancer 5.6
Hypertrophic 5.6
malignant pleural effusion 5.6
diffuse scleroderma 5.5
hormone refractory prostate cancer 5.5
neovascular glaucoma 5.4
metastatic renal cell carcinoma 5.4
AIDS-related Kaposi's sarcoma 5.4
metastatic neuroblastoma 5.4
OCP 5.4
VISA 5.3
macular degeneration 5.3
tuberculous pleurisy 5.3
potassium deficiency 5.3
Liver regeneration 5.3
Granuloma 5.2
Sutton 5.2
lung metastases 5.2
DIG 5.2
Choroid 5.1
Choroid 5.1
HGF 5.0
gastrointestinal dysfunction 5.0
brain metastases 4.9
retinopathy of prematurity 4.9
collagen disease 4.9
diabetic retinopathy 4.9
FPP 4.9
squamous cell carcinoma of the skin 4.8
Age-related macular degeneration 4.8
metastatic pancreatic cancer 4.8
metastatic colon cancer 4.8
FHA 4.7
metastatic gastric cancer 4.7
lung carcinoma 4.7
macular edema 4.7
TEC 4.7
solid tumor 4.7
collagen disease 4.7
juvenile myelomonocytic leukemia 4.7
non-small cell lung cancer 4.6
Zinc deficiency 4.6
carcinomatosis 4.6
spastic diplegia 4.5
arteriopathy 4.5
fetal hypoxia 4.5
Beard 4.4
Tumour necrosis 4.4
chronic ischemic heart disease 4.4
tumor progression 4.4
ATRX 4.4
lymphatic vessels 4.4
glioblastoma 4.4
ATN 4.3
glioblastoma multiforme 4.3
Hepatocellular carcinoma 4.3
EIA 4.3
gliosarcoma 4.3
chlorosis 4.3
macular hole 4.2
tetany 4.2
PDR 4.2
leukoencephalopathy 4.2
metastatic breast cancer 4.2
PSS 4.2
recurrent breast cancer 4.1
primary tumor 4.1
Wilson's disease 4.1
Tag 4.1
cervical dysplasia 4.1
lentigo 4.1
mammary tumor 4.1
PCT 4.1
mimicry 4.1
nephrosclerosis 4.1
renal cell carcinoma 4.1
liver cancer 4.0
desmoid 4.0
glioma 4.0
Lennox-Gastaut syndrome 4.0
CTX 4.0
rind 4.0
myopia 4.0
liver cancer 4.0
CEP 4.0
B-cell chronic lymphocytic leukemia 4.0
SCID 3.9
HTS 3.9
Colorectal Cancer 3.9
skin tumor 3.9
Hypertrophic cardiomyopathy 3.9
liver metastases 3.9
immunotoxicity 3.9
Jensen 3.9
Robinson 3.8
Rosenthal 3.8
Glioblastoma 3.8
retinal detachment 3.8
HCC 3.8
intellectual impairment 3.8
angiosarcoma 3.8
moyamoya 3.8
gynecologic cancer 3.8
protein-losing enteropathy 3.8
epithelial ovarian cancer 3.7
myoma 3.7
strongyloidiasis 3.7
brain cancer 3.7
GCE 3.7
colon cancer 3.7
CNS tumors 3.7
conversion reaction 3.7
carcinoma of the pancreas 3.7
familial adenomatous polyposis 3.7
PAL 3.7
Osteosarcoma 3.7
Osteosarcoma 3.7
proctitis 3.7
ALD 3.7
brain tumor 3.7
Neuroblastoma 3.6
Neuroblastoma 3.6
spondyloarthropathy 3.6
NOD 3.6
Wiskott-Aldrich syndrome 3.6
HOS 3.6
CAM 3.6
more...
Symptom
Continuous leakage 12.8
Halo 4.9
abdominal cramps 4.7
atypical chest pain 4.4
rigors 4.1
microbial colonization 3.7
hypoproteinemia 3.6
hemoptysis 3.2
hyperoxia 3.0
Wind 2.4
dry eye 2.4
asthenia 2.4
hoarseness 2.2
agitation 2.2
acidity 2.2
nausea and vomiting 2.1
nausea 2.1
constipation 2.0
thinning 1.9
cyanosis 1.9
dysarthria 1.9
starvation 1.7
hepatosplenomegaly 1.7
diarrhea 1.5
fatigue 1.4
numbness 1.4
vomiting 1.4
lethargy 1.3
chest pain 1.3
hypotonia 1.3
tremor 1.2
flushing 1.1
overweight 1.1
functional recovery 1.1
anorexia 1.0
collapse 1.0
insomnia 0.4
cough 0.2
sleepiness 0.1
ataxia -0.2
headache -0.4
weakness -0.4
respiratory distress -0.5
discomfort -0.7
discomfort -0.8
dyspnea -1.0
pain -1.1
anesthesia -2.0
seizures -2.5
Drug
Pipamperone 9.9
Magnesium phosphate 9.5
Gentian violet 9.3
Sensodyne 9.2
Proleukin 8.7
Bevacizumab 8.6
Marimastat 7.6
Trifluoroethanol 7.5
PZC 7.1
Axitinib 6.7
RbCl 6.7
RbCl 6.7
Hyperforin 6.7
Sunitinib malate 6.6
KGF 6.4
2-Methoxyestradiol 6.4
Malachite Green 6.3
Everolimus 6.3
Navelbine 6.3
CTT 6.1
NOV 6.0
Talc 6.0
Ammonium chloride 5.9
Cetuximab 5.9
EHDP 5.8
LMWH 5.7
TES 5.6
Perindopril 5.4
anti-CD33 5.4
Erlotinib 5.2
Sorafenib 5.2
Orlistat 5.2
Dextrose 5.1
Doyle 5.1
Vinorelbine 5.0
Zoledronic acid 4.8
Citric acid 4.8
Imiquimod 4.7
Orphan 4.7
Etoposide 4.6
Docetaxel 4.6
NaI 4.5
NaI 4.5
NaI 4.5
NaI 4.5
CoCl2 4.5
CoCl2 4.5
DPA 4.5
IL-1ra 4.3
uPA 4.3
Zoledronic acid 4.1
CTX 4.1
TAC 4.1
Irinotecan 4.1
CTX 4.1
Xanthium 4.1
Bifidobacterium 4.1
Alanine 3.9
Itraconazole 3.8
Omeprazole 3.8
CTX 3.8
Fragment 3.6
CAM 3.6
AMC 3.6
Gefitinib 3.5
Arsenic trioxide 3.5
Nitric Oxide 3.4
CTA 3.3
Glycyrrhiza 3.3
Bortezomib 3.2
BH4 3.2
GEO 3.2
Ranitidine 3.1
Acacia 3.1
citric acid 3.1
Simvastatin 3.1
Activin 3.0
Gelatin 3.0
CPT-11 2.9
ROC 2.8
NADH 2.8
EPI 2.7
Herceptin 2.6
Adriamycin 2.6
Silica 2.5
Rituximab 2.3
ascorbate 2.3
MOF 2.2
IFN-beta 2.2
Taxol 2.1
MRC 2.0
vitamin E 2.0
Leaf 1.9
niacin 1.9
Spectrum 1.8
ABC 1.7
Gel 1.5
MAP 1.4
lysine 1.4
Glutathione 1.4
ICI 1.4
Indomethacin 1.1
PTH 1.0
Monit 0.7
Nephron 0.6
ROS 0.5
IFN-gamma 0.5
IL-2 0.5
CSF 0.4
Asn 0.2
ampicillin -0.3
Dermatol -2.2
Cardiovasc -2.8
Enzyme
cathepsin V 8.8
EC 2.7.1.90 8.6
threonine synthase 7.5
TSP-1 7.2
uracil phosphoribosyltransferase 7.1
procollagen C-proteinase 7.1
saccharopine dehydrogenase 6.9
CTP synthase 6.8
nitrate reductase 6.8
nitrate reductase 6.8
nitrate reductase 6.8
nitrate reductase 6.8
nitrate reductase 6.8
nitrate reductase 6.8
dihydrodipicolinate synthase 6.5
cytosine deaminase 6.5
glycolate oxidase 6.3
pregnancy-associated plasma protein-A 6.0
mercuric reductase 5.9
3-mercaptopyruvate sulfurtransferase 5.9
cathepsin L 5.8
lysyl hydroxylase 5.8
cathepsin S 5.8
sucrose synthase 5.8
biliverdin reductase 5.6
4CL 5.4
SMP 5.3
anthranilate synthase 5.3
threonine deaminase 5.2
nitrite reductase 5.2
nitrite reductase 5.2
catechol 2,3-dioxygenase 5.2
nitrite reductase 5.2
aspartokinase 5.1
carboxypeptidase E 5.1
lysyl oxidase 5.1
heparinase 5.0
MMP 5.0
arginine deiminase 5.0
proton-translocating ATPase 4.9
glutamine synthetase 4.8
nitrogenase 4.8
SPT 4.7
glycine decarboxylase 4.6
phosphoenolpyruvate carboxylase 4.6
1-hydroxylase 4.6
MTD 4.5
carboxypeptidase B 4.5
acetolactate synthase 4.5
glutathione synthetase 4.4
MMP-3 4.4
fatty acid desaturase 4.3
SOR 4.3
CEP 4.2
glutamate synthase 4.2
glutamate synthase 4.2
ascorbate oxidase 4.2
glutamate synthase 4.1
SPS 4.1
methane monooxygenase 4.1
pyruvate decarboxylase 4.0
urokinase-type plasminogen activator 4.0
SPT 4.0
delta-aminolevulinic acid dehydratase 3.9
BIS 3.9
carboxypeptidase A 3.8
plasmin 3.8
chondroitinase 3.8
thymidine phosphorylase 3.8
ECH 3.7
sorbitol dehydrogenase 3.7
collagenase 3.7
chondroitinase 3.7
CEP 3.7
xanthine dehydrogenase 3.5
cellulose synthase 3.5
TPP 3.4
NO synthase 3.4
rubisco 3.4
ERK 3.3
cathepsin B 3.3
TPP 3.3
MAP 3.2
caspase-9 3.2
chalcone synthase 3.2
protein phosphatase 2A 3.2
apyrase 3.2
isocitrate dehydrogenase 3.2
PAL 3.1
leucine aminopeptidase 3.1
ceruloplasmin 3.0
caspase-8 3.0
isocitrate dehydrogenase 3.0
tryptophan hydroxylase 3.0
caspase-3 3.0
CD13 3.0
cathepsin G 3.0
prolyl hydroxylase 2.9
NOS 2.9
cathepsin K 2.9
TdT 2.9
BAL 2.8
cathepsin D 2.8
hyaluronidase 2.8
cdc2 2.7
xylanase 2.7
PAL 2.7
NADH dehydrogenase 2.7
ribonuclease 2.7
matrix metalloproteinase 9 2.7
ribonuclease 2.7
xylanase 2.7
PAH 2.7
phosphatidylinositol 3-kinase 2.7
NADPH oxidase 2.6
tissue plasminogen activator 2.6
PARP 2.6
elastase 2.6
matrix metalloproteinase 2 2.6
glutathione reductase 2.5
transglutaminase 2.5
MIP 2.5
thioredoxin reductase 2.5
luciferase 2.5
asparaginase 2.4
glucose oxidase 2.4
focal adhesion kinase 2.3
firefly luciferase 2.3
ascorbate peroxidase 2.3
guanylate cyclase 2.3
diaphorase 2.2
mitogen-activated protein kinase 2.2
kallikrein 2.2
5'-nucleotidase 2.1
ornithine decarboxylase 2.1
CPT 2.1
proteasome 2.1
GSK 2.0
HSD 2.0
CPT 2.0
prostate-specific antigen 2.0
chymotrypsin 1.9
carbonic anhydrase 1.9
thymidine kinase 1.9
proteinase K 1.8
phosphoenolpyruvate carboxykinase 1.7
phosphoenolpyruvate carboxykinase 1.7
ATPase 1.7
glutamate dehydrogenase 1.7
ACS 1.7
glutamate dehydrogenase 1.7
CAD 1.7
aldehyde dehydrogenase 1.7
aldehyde dehydrogenase 1.7
CAD 1.7
glutamate dehydrogenase 1.7
aldehyde dehydrogenase 1.6
RNase 1.6
MEK 1.6
CAD 1.6
more...
Compound
2-amino-1-propanol 9.8
2-amino-1-butanol 9.8
2-amino-1,3-propanediol 9.5
Cytochalasin E 9.1
2-(2-methoxyethoxy)ethanol 9.0
HM-3 8.9
DNBA 8.9
Combretum caffrum 8.4
2-bromoethanesulfonic acid 8.1
Xylenol Orange 8.1
TAPS 8.1
Potassium bromate 7.8
3-chlorophenol 7.7
2-chlorobenzoate 7.7
Nedaplatin 7.6
Combretum caffrum 7.6
2-amino-2-methyl-1-propanol 7.5
2-methylpropanal 7.5
2-methylpropanal 7.5
Propyl gallate 7.5
Cantril 7.5
2-methylpropanal 7.5
2-methylpropanal 7.4
2-amino-2-methyl-1-propanol 7.4
allantoate 7.3
p-Cymene 7.3
AMPD 7.2
2-methylbutanal 7.2
Combretastatin A4 7.2
cinnoline 7.1
01M 7.0
Canavanine 7.0
Combretastatin 7.0
Piperlongumine 7.0
Zinc protoporphyrin 6.9
8-quinolinol 6.8
8-quinolinol 6.8
8-quinolinol 6.8
8-quinolinol 6.8
8-quinolinol 6.8
2-methylpropanal 6.8
8-quinolinol 6.8
A 150 6.7
Hyperforin 6.7
LNT 6.7
Heparan sulfate 6.7
Iodoacetamide 6.6
Doxazosin 6.6
OCTA 6.6
PZC 6.5
1,4,8,11-tetraazacyclotetradecane 6.5
1-propanesulfonic acid 6.5
2-Methoxyestradiol 6.4
ADMA 6.4
1-pentanol 6.3
8-quinolinol 6.2
PAE 6.2
Mesalamine 6.2
Isatin 6.2
Flavone 6.1
propionaldehyde 6.1
1-decanol 6.1
TES 6.1
EHDP 6.0
8-quinolinol 6.0
Salinomycin 6.0
iduronate 5.9
methylphosphonic acid 5.9
methylphosphonic acid 5.9
2-chlorophenol 5.9
methylphosphonic acid 5.9
2-chlorophenol 5.8
3-methylbutanal 5.8
Tetrandrine 5.8
Tetrandrine 5.8
Tetrandrine 5.8
Tetrandrine 5.8
trimethyllysine 5.8
H-3 5.7
Pamidronate 5.7
Nitrate 5.7
Neo 5.7
Malate 5.6
Collagen 5.6
Clavulanic acid 5.6
Calcium carbonate 5.6
Perindopril 5.6
Hypericin 5.6
AAB 5.5
AAB 5.5
octadecane 5.5
trioctylphosphine 5.4
nitrate 5.4
Nystatin 5.4
Nystatin 5.4
Phalloidin 5.4
Vinca 5.4
dimethyl carbonate 5.3
DDQ 5.3
Tetrahydrobiopterin 5.3
Ticlopidine 5.3
Alginate 5.2
trifluoroacetic anhydride 5.2
K19 5.2
Nitrite 5.1
G20 5.1
Kanamycin 5.0
Morin 5.0
Thiocyanate 5.0
Lawson 5.0
SP-1 5.0
ethyl acrylate 4.9
NNN 4.9
Docetaxel 4.9
APN 4.9
Malachite Green 4.9
BIC 4.9
Celecoxib 4.9
Nitrite 4.8
KOH 4.8
Triptolide 4.8
Tanshinone 4.8
Zirconia 4.8
DHBA 4.8
CPA 4.8
ECP 4.7
DEC 4.7
Chlorogenic acid 4.7
ECP 4.7
ECP 4.7
TEC 4.7
DPA 4.7
DPA 4.7
Astaxanthin 4.7
CPA 4.6
3-hydroxybutyric acid 4.6
DHBA 4.6
Hydroxyurea 4.6
CPA 4.6
ACI 4.6
PGJ2 4.6
SCN 4.6
Phytic acid 4.6
Cytochalasin D 4.5
DPA 4.5
1-hexanol 4.5
Etanercept 4.5
CCS 4.5
DPA 4.5
TSC 4.5
Ach 4.4
DPA 4.4
TET 4.4
TET 4.4
ClO 4.4
butyl acrylate 4.4
EPC 4.4
PPA 4.4
Cu(II) 4.4
PPi 4.4
more...