Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P39060 (
endostatin
)
2,284
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This work describes the application of polarography, a technique scarcely used for modelling and optimisation of stability constants, in the study of copper complexes with [(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid (TAPS). Direct current polarography (DCP), using low total copper ion and large total ligand to total copper concentration, enabled the full characterization of Cu-(TAPS)(x)-(OH)(y) system, whose complexation occurs in the pH range of copper hydrolysis and Cu(OH)(2) precipitation. Cu-(TAPS)(x)-(OH)(y) system was studied by DCP and glass electrode potentiometry (GEP) in aqueous solution at fixed total ligand to total metal concentrations ratios and varied pH values (25.0 degrees C; I=0.1M,
KNO
(3)). The predicted model, as well as the overall stability constants values, are (as logbeta): CuL(+)=4.2, CuL(2)=7.8, CuL(2)(OH)(-)=13.9 and CuL(2)(OH)(2)(2-)=18.94. GEP only allowed confirming the stability constants for CuL(+) and CuL(2) and was used to determine the pK(a) of TAPS, 8.342. Finally, a briefly comparative analysis between TAPS and other structural related buffers was done. Evaluation based on logbeta(CuL) versus pK(a) revealed that
TES
, TRIS, TAPS and AMPSO coordinated via amino and hydroxymethylgroups forming a five-membered chelate ring. For BIS-TRIS and TAPSO, and possibly DIPSO, one or more five-membered chelate rings involving additional hydroxyl groups are also likely formed.
...
PMID:Challenges in modelling and optimisation of stability constants in the study of Cu-(TAPS)(x)-(OH)(y) system by polarography. 1907 57
Eutectic molten salts are the most studied medium-high temperature thermal energy storage material due to their potential use in concentrated solar power plants. The aim of this work is to investigate the effect of using reduced graphene oxide (RGO) and graphene quantum dots (GQDs) on the thermal properties of eutectic molten salts. A binary nitrate eutectic mixture of NaNO
3
and
KNO
3
was selected as a base material (BM) for nitrate/carbon-derivative composites. RGO and GQDs were individually mixed with the BM with different fractions ranged from 0.1 to 1.5 wt %. The results showed that RGO enhanced the thermal conductivity, heat of fusion, and total thermal energy storage capacity by 52.10%, 44.48%, and 10.44%, respectively. GQDs slightly improved the specific heat capacity for both solid and liquid phases by 2.53% and 3.13%, respectively. In addition, GQDs promoted the heat of fusion by 31.72% and raised the total
TES
capacity by 12.26%.
...
PMID:Enhancement of Molten Nitrate Thermal Properties by Reduced Graphene Oxide and Graphene Quantum Dots. 3290 10
