Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P36969 (
phospholipid hydroperoxide glutathione peroxidase
)
344
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Malondialdehyde
(
MDA
), a product involved in membrane lipid peroxidation, was dosed in the sperm of 163 patients who had consulted the clinic regarding hypofertility. We attempted to determine if there was correlation between
MDA
content, sperm World Health Organization parameters and DNA fragmentation that results mainly from reactive oxygen species assaults. We found that no correlation could be established; however
MDA
and sperm decondensation were shown to be significantly linked. The impact of membrane polyunsaturated fatty acids and the role of
phospholipid hydroperoxide glutathione peroxidase
are discussed.
...
PMID:Malonaldehyde formation and DNA fragmentation: two independent sperm decays linked to reactive oxygen species. 2033 8
