Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P33527 (
ABCC1
)
1,164
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ABCC1
1164
ABCB1
407
P-glycoprotein
333
ABCG2
330
MRP1
320
multidrug resistance-associated protein
276
ATP-binding cassette
269
ATP
165
ABC
130
BCRP
120
ABCC2
118
MDR1
114
breast cancer resistance protein
107
Mol
106
ABC transporter
101
MRP2
99
Sep
90
P-gp
87
ATPase
75
GSH
75
multidrug resistance protein 1
73
MRP3
60
ABCC3
58
MRP4
47
ABCC4
45
MRP
38
ABCC5
34
MRP5
32
multidrug resistance protein
32
ABCC
32
ATP-binding cassette transporter
29
ABCC6
29
tyrosine kinase
27
polypeptide
23
xenobiotic
23
mdr1
23
ABCC10
21
ADR
21
p53
20
cytochrome P450
18
glycoprotein
17
CYP3A4
17
Breast Cancer Resistance Protein
17
organic anion transporter
15
ABCA1
15
glutathione S-transferase
15
organic anion transporting polypeptide
15
OATP2B1
14
ABCB11
14
GST
14
ABCG1
13
OATP1B1
13
MRP6
13
Bcl-2
13
ABCC7
13
CFTR
12
OATP1B3
12
EGFR
11
membrane-bound
11
caspase-3
11
Multidrug resistance protein 1
11
AKT
11
GS-X
10
topoisomerase I
10
member 1
10
metallothionein
10
cystic fibrosis transmembrane conductance regulator
10
UGT1A1
10
gut
10
ABCA2
10
ABCA3
10
multidrug resistance-related protein
10
sulfonylurea receptor
10
SLCO1B1
10
canalicular multispecific organic anion transporter
10
CD34
9
UTR
9
organic cation transporter
9
CD44
9
LRP
9
more...
Disease
cancer
428
tumor
202
GSH
75
breast cancer
64
leukemia
47
lung cancer
46
acute myeloid leukemia
38
carcinoma
34
MCF
32
colorectal cancer
26
hepatocellular carcinoma
25
adenocarcinoma
20
ovarian cancer
20
acute lymphoblastic leukemia
18
tumor growth
18
colon cancer
17
neuroblastoma
16
epithelial ovarian cancer
15
Leukemia
15
melanoma
14
Alzheimer's disease
14
non-small cell lung cancer
14
small cell lung cancer
14
lymphoma
13
CEM
12
squamous cell carcinoma
12
gastric cancer
12
prostate cancer
11
chronic myeloid leukemia
11
acute promyelocytic leukemia
11
tumorigenesis
10
lung carcinoma
10
pseudoxanthoma elasticum
10
tumor progression
10
epilepsy
9
neutropenia
9
osteosarcoma
8
HIV
8
liver cancer
8
carcinogenesis
8
cystic fibrosis
8
multiple myeloma
8
childhood ALL
8
metastases
8
solid tumor
7
renal cell carcinoma
7
immunodeficiency
7
sarcoma
7
bladder cancer
6
glioma
6
ABL
6
DDP
6
mitral valve prolapse
6
stromal tumors
6
HCC
6
Melanoma
5
MMA
5
glioblastoma
4
asthma
4
myeloid leukemia
4
Hepatocellular carcinoma
4
hyperbilirubinemia
4
SCID
4
stroke
4
diabetes
4
dementia
4
Dubin-Johnson syndrome
4
hypertension
4
myelodysplastic syndrome
4
chronic obstructive pulmonary disease
4
ATM
3
acute leukemia
3
genetic disorder
3
glioblastoma multiforme
3
tuberculosis
3
chronic lymphocytic leukemia
3
pancreatic cancer
3
Colon cancer
3
PML
3
rheumatoid arthritis
3
more...
Symptom
diarrhea
3
seizures
2
starvation
1
asthenia
1
pain
1
spasticity
1
memory loss
1
hypothermia
1
hepatomegaly
1
bitter taste
1
splenomegaly
1
nausea and vomiting
1
Decreased activity
1
Drug
ABC
130
ADR
21
Glutathione
12
CPT-11
10
Adriamycin
9
Dermatol
5
CSF
5
Gleevec
4
Cremophor EL
4
VCR
4
Taxol
4
ADM
4
VCR
4
ROS
4
Adenosine triphosphate
4
Arsenic trioxide
4
Mutagen
2
Bortezomib
2
Etoposide
2
lysine
2
Gefitinib
2
Docetaxel
2
Imatinib
2
DM1
2
Asthma
2
Sunitinib malate
2
Irinotecan
2
PMEA
2
Ouabain
2
Pemetrexed
1
Vitamin K
1
Raloxifene
1
GEO
1
Olmesartan
1
Monit
1
Portal
1
TTC
1
balanced salt solution
1
AraC
1
Leaf
1
Fluorescein
1
EE2
1
ROC
1
Emodin
1
Indomethacin
1
G418
1
Vitamin E
1
Gemfibrozil
1
DNase I
1
TAK
1
anti-CD33
1
THF
1
NovoSeven
1
Cobalamin
1
ampicillin
1
Asn
1
Azithromycin
1
MAP
1
Glycyrrhiza
1
AZT
1
Hectorol
1
Rutin
1
Fluorescein sodium
1
Salicylate
1
Vitamin B12
1
Budesonide
1
Alanine
1
Itraconazole
1
ascorbate
1
Alimta
1
Primaquine
1
Sorafenib
1
IFN-gamma
1
Ranitidine
1
EPI
1
NVP
1
Ginger
1
Gel
1
Flavopiridol
1
Cetuximab
1
more...
Enzyme
P-glycoprotein
335
ATPase
75
MDR
35
topoisomerase
29
glutathione S-transferase
27
topoisomerase
25
ERK
22
luciferase
19
CYP3A4
17
reverse transcriptase
15
focal adhesion kinase
14
mitogen-activated protein kinase
13
gamma-glutamylcysteine synthetase
10
protein kinase
9
RNase
9
RNase
9
caspase-3
8
UDP-glucuronosyltransferase
7
thymidylate synthase
6
phosphatidylinositol 3-kinase
5
phosphodiesterase
5
deoxycytidine kinase
5
catalase
5
lactate dehydrogenase
5
glutathione peroxidase
4
ACS
4
RNA polymerase
4
glyceraldehyde-3-phosphate dehydrogenase
4
protein kinase C
4
glutathione reductase
4
transcriptase
4
LTA4 hydrolase
4
trypsin
4
folylpolyglutamate synthetase
3
sphingosine kinase
3
IKK
3
dihydropyrimidine dehydrogenase
3
NQO1
3
dihydropyrimidine dehydrogenase
3
PARP
3
phospholipase C
2
MEK
2
cysteine synthase
2
asparaginase
2
phosphoglycerate kinase
2
superoxide dismutase
2
adenosine deaminase
2
HIV-1 protease
2
Mg2+-ATPase
2
adenosine deaminase
2
phospholipase A2
2
proteasome
2
5'-nucleotidase
1
neuraminidase
1
guanylate cyclase
1
chalcone synthase
1
protein phosphatase 2A
1
ATP synthase
1
carboxylesterase
1
chymotrypsin
1
glyceraldehyde-3-phosphate dehydrogenase
1
beta-secretase
1
PAL
1
APC
1
aldose reductase
1
biliverdin reductase
1
ribonuclease
1
alanine aminotransferase
1
endoglycosidase H
1
Pla
1
caspase-9
1
CD10
1
mu-calpain
1
histidine permease
1
ALDH
1
firefly luciferase
1
arachidonate 5-lipoxygenase
1
glucose-6-phosphate dehydrogenase
1
ribonuclease
1
hyaluronidase
1
more...
Compound
ATP
165
Dec
89
GSH
80
GSH
80
DNA
79
MTT
44
Clin
37
MDR
35
sulfate
29
ADR
29
sodium
21
SN-38
21
oxygen
19
phosphate
19
Adriamycin
18
VP-16
16
LTC4
15
MDA
15
cadmium
13
bromide
13
Hoechst 33342
12
DDP
11
water
11
alanine
11
CPT-11
10
Paclitaxel
10
diacetate
10
calcium
9
GSSG
8
pyrene
8
ADP
8
ADP
8
ADP
8
potassium
8
cysteine
8
ABL
7
Vinca
7
BCR
7
BSO
6
Curcumin
6
Verapamil
6
Verapamil
6
tyrosine
6
cGMP
6
iron
6
galactose
6
ethanol
5
MMA
5
chalcone
5
tryptophan
5
MMA
5
lysine
5
MMA
5
threonine
5
tryptophan
5
pyrimidine
5
UDP
5
DNP
5
tryptophan
5
salt
5
glucose
5
cAMP
5
pyrimidine
5
tryptophan
5
Probenecid
5
quinoline
5
dimethylarsinic acid
4
selenium
4
Genistein
4
Vincristine
4
nitric oxide
4
dimethylarsinic acid
4
DMA
4
dimethylarsinic acid
4
PEG
4
copper
4
Rhodamine 123
4
His
4
Gemcitabine
4
PEG
4
more...