Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P33527 (ABCC1)
1,164 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ABCC1 1164
ABCB1 407
P-glycoprotein 333
ABCG2 330
MRP1 320
multidrug resistance-associated protein 276
ATP-binding cassette 269
ATP 165
ABC 130
BCRP 120
ABCC2 118
MDR1 114
breast cancer resistance protein 107
Mol 106
ABC transporter 101
MRP2 99
Sep 90
P-gp 87
ATPase 75
GSH 75
multidrug resistance protein 1 73
MRP3 60
ABCC3 58
MRP4 47
ABCC4 45
MRP 38
ABCC5 34
MRP5 32
multidrug resistance protein 32
ABCC 32
ATP-binding cassette transporter 29
ABCC6 29
tyrosine kinase 27
polypeptide 23
xenobiotic 23
mdr1 23
ABCC10 21
ADR 21
p53 20
cytochrome P450 18
more...
Disease
cancer 428
tumor 202
GSH 75
breast cancer 64
leukemia 47
lung cancer 46
acute myeloid leukemia 38
carcinoma 34
MCF 32
colorectal cancer 26
hepatocellular carcinoma 25
ovarian cancer 20
adenocarcinoma 20
acute lymphoblastic leukemia 18
tumor growth 18
colon cancer 17
neuroblastoma 16
epithelial ovarian cancer 15
Leukemia 15
small cell lung cancer 14
melanoma 14
Alzheimer's disease 14
non-small cell lung cancer 14
lymphoma 13
gastric cancer 12
squamous cell carcinoma 12
CEM 12
acute promyelocytic leukemia 11
prostate cancer 11
chronic myeloid leukemia 11
tumorigenesis 10
tumor progression 10
lung carcinoma 10
pseudoxanthoma elasticum 10
epilepsy 9
neutropenia 9
metastases 8
multiple myeloma 8
HIV 8
carcinogenesis 8
more...
Symptom
diarrhea 3
seizures 2
starvation 1
asthenia 1
pain 1
spasticity 1
memory loss 1
hypothermia 1
hepatomegaly 1
bitter taste 1
splenomegaly 1
nausea and vomiting 1
Decreased activity 1
Drug
ABC 130
ADR 21
Glutathione 12
CPT-11 10
Adriamycin 9
Dermatol 5
CSF 5
ADM 4
Cremophor EL 4
ROS 4
Taxol 4
VCR 4
VCR 4
Adenosine triphosphate 4
Gleevec 4
Arsenic trioxide 4
Asthma 2
Mutagen 2
Imatinib 2
Bortezomib 2
Sunitinib malate 2
PMEA 2
Docetaxel 2
Ouabain 2
Gefitinib 2
Irinotecan 2
lysine 2
DM1 2
Etoposide 2
Hectorol 1
AZT 1
GEO 1
Monit 1
ascorbate 1
Portal 1
balanced salt solution 1
EPI 1
AraC 1
Leaf 1
Fluorescein 1
more...
Enzyme
P-glycoprotein 335
ATPase 75
MDR 35
topoisomerase 29
glutathione S-transferase 27
topoisomerase 25
ERK 22
luciferase 19
CYP3A4 17
reverse transcriptase 15
focal adhesion kinase 14
mitogen-activated protein kinase 13
gamma-glutamylcysteine synthetase 10
RNase 9
RNase 9
protein kinase 9
caspase-3 8
UDP-glucuronosyltransferase 7
thymidylate synthase 6
phosphodiesterase 5
phosphatidylinositol 3-kinase 5
deoxycytidine kinase 5
lactate dehydrogenase 5
catalase 5
RNA polymerase 4
transcriptase 4
glyceraldehyde-3-phosphate dehydrogenase 4
ACS 4
trypsin 4
LTA4 hydrolase 4
protein kinase C 4
glutathione reductase 4
glutathione peroxidase 4
folylpolyglutamate synthetase 3
PARP 3
sphingosine kinase 3
dihydropyrimidine dehydrogenase 3
NQO1 3
dihydropyrimidine dehydrogenase 3
IKK 3
more...
Compound
ATP 165
Dec 89
GSH 80
GSH 80
DNA 79
MTT 44
Clin 37
MDR 35
ADR 29
sulfate 29
SN-38 21
sodium 21
phosphate 19
oxygen 19
Adriamycin 18
VP-16 16
MDA 15
LTC4 15
bromide 13
cadmium 13
Hoechst 33342 12
alanine 11
water 11
DDP 11
Paclitaxel 10
diacetate 10
CPT-11 10
calcium 9
pyrene 8
GSSG 8
ADP 8
cysteine 8
potassium 8
ADP 8
ADP 8
Vinca 7
ABL 7
BCR 7
iron 6
Verapamil 6
more...