Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P33527 (ABCC1)
 1,164 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ABCC1 1164
ABCB1 407
P-glycoprotein 333
ABCG2 330
MRP1 320
multidrug resistance-associated protein 276
ATP-binding cassette 269
ATP 165
ABC 130
BCRP 120
ABCC2 118
MDR1 114
breast cancer resistance protein 107
Mol 106
ABC transporter 101
MRP2 99
Sep 90
P-gp 87
ATPase 75
GSH 75
more...
Disease
cancer 428
tumor 202
GSH 75
breast cancer 64
leukemia 47
lung cancer 46
acute myeloid leukemia 38
carcinoma 34
MCF 32
colorectal cancer 26
hepatocellular carcinoma 25
ovarian cancer 20
adenocarcinoma 20
acute lymphoblastic leukemia 18
tumor growth 18
colon cancer 17
neuroblastoma 16
epithelial ovarian cancer 15
Leukemia 15
melanoma 14
more...
Symptom
diarrhea 3
seizures 2
starvation 1
asthenia 1
pain 1
spasticity 1
memory loss 1
hypothermia 1
hepatomegaly 1
bitter taste 1
splenomegaly 1
nausea and vomiting 1
Decreased activity 1
Drug
ABC 130
ADR 21
Glutathione 12
CPT-11 10
Adriamycin 9
Dermatol 5
CSF 5
ADM 4
ROS 4
Cremophor EL 4
VCR 4
VCR 4
Taxol 4
Adenosine triphosphate 4
Gleevec 4
Arsenic trioxide 4
Docetaxel 2
Asthma 2
Sunitinib malate 2
Gefitinib 2
more...
Enzyme
P-glycoprotein 335
ATPase 75
MDR 35
topoisomerase 29
glutathione S-transferase 27
topoisomerase 25
ERK 22
luciferase 19
CYP3A4 17
reverse transcriptase 15
focal adhesion kinase 14
mitogen-activated protein kinase 13
gamma-glutamylcysteine synthetase 10
protein kinase 9
RNase 9
RNase 9
caspase-3 8
UDP-glucuronosyltransferase 7
thymidylate synthase 6
lactate dehydrogenase 5
more...
Compound
ATP 165
Dec 89
GSH 80
GSH 80
DNA 79
MTT 44
Clin 37
MDR 35
ADR 29
sulfate 29
sodium 21
SN-38 21
phosphate 19
oxygen 19
Adriamycin 18
VP-16 16
MDA 15
LTC4 15
bromide 13
cadmium 13
more...