Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P33527 (ABCC1)
 1,164 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ABCC1 1164
ABCB1 407
P-glycoprotein 333
ABCG2 330
MRP1 320
multidrug resistance-associated protein 276
ATP-binding cassette 269
ATP 165
ABC 130
BCRP 120
ABCC2 118
MDR1 114
breast cancer resistance protein 107
Mol 106
ABC transporter 101
MRP2 99
Sep 90
P-gp 87
GSH 75
ATPase 75
multidrug resistance protein 1 73
MRP3 60
ABCC3 58
MRP4 47
ABCC4 45
MRP 38
ABCC5 34
ABCC 32
multidrug resistance protein 32
MRP5 32
ABCC6 29
ATP-binding cassette transporter 29
tyrosine kinase 27
polypeptide 23
xenobiotic 23
mdr1 23
ADR 21
ABCC10 21
p53 20
cytochrome P450 18
CYP3A4 17
Breast Cancer Resistance Protein 17
glycoprotein 17
organic anion transporter 15
glutathione S-transferase 15
ABCA1 15
organic anion transporting polypeptide 15
GST 14
OATP2B1 14
ABCB11 14
ABCC7 13
Bcl-2 13
ABCG1 13
OATP1B1 13
MRP6 13
CFTR 12
OATP1B3 12
EGFR 11
Multidrug resistance protein 1 11
AKT 11
membrane-bound 11
caspase-3 11
multidrug resistance-related protein 10
canalicular multispecific organic anion transporter 10
ABCA3 10
ABCA2 10
cystic fibrosis transmembrane conductance regulator 10
GS-X 10
member 1 10
UGT1A1 10
sulfonylurea receptor 10
gut 10
topoisomerase I 10
metallothionein 10
SLCO1B1 10
CD34 9
CD44 9
UTR 9
multidrug resistance protein 2 9
LRP 9
organic cation transporter 9
gamma-glutamylcysteine synthetase 9
RNase 8
BCL2 8
pseudoxanthoma elasticum 8
ADP 8
CYP3A5 8
ABCC9 8
AML 8
solute carrier 8
transporter protein 8
MRP-1 8
Nrf2 8
ABCB6 8
ABCC11 8
GSTP1 8
estrogen receptor 7
ALOX5 7
osteosarcoma 7
ABCB4 7
CD133 7
HEK 7
ABCF2 7
membrane protein 7
OCT1 7
BCR 7
ABCA7 7
GCS 7
HDAC1 6
ABC protein 6
ABCB5 6
ABL 6
HCC 6
topoisomerase II alpha 6
epidermal growth factor receptor 6
MVP 6
CYP2D6 6
DNA gyrase 6
Multidrug resistance protein 6
ABC-transporter 6
SLC22A1 6
CYP2C8 6
major vault protein 6
GSTM1 6
thymidylate synthase 6
BAX 6
Bcl-X 6
glutathione S-transferase pi 6
IL-6 5
SLCO1B3 5
lactate dehydrogenase 5
OAT1 5
organic cation transporter 1 5
catenin 5
microsomal 5
L23 5
OATP3A1 5
CYP1A2 5
CD4 5
NMR 5
bcl-2 5
NR1I2 5
histone 5
MMA 5
phosphodiesterase 5
SUR1 5
CYP2B6 5
DDP 5
proximal tubule 5
CSF 5
CYP2C19 5
deoxycytidine kinase 5
cytokine 5
PI3K 5
DNA topoisomerase I 5
CCL21 5
CASP3 5
ERK 5
1A1 5
phosphatidylinositol 3-kinase 5
more...
Disease
cancer 428
tumor 202
GSH 75
breast cancer 64
leukemia 47
lung cancer 46
acute myeloid leukemia 38
carcinoma 34
MCF 32
colorectal cancer 26
hepatocellular carcinoma 25
adenocarcinoma 20
ovarian cancer 20
tumor growth 18
acute lymphoblastic leukemia 18
colon cancer 17
neuroblastoma 16
epithelial ovarian cancer 15
Leukemia 15
non-small cell lung cancer 14
Alzheimer's disease 14
melanoma 14
small cell lung cancer 14
lymphoma 13
gastric cancer 12
CEM 12
squamous cell carcinoma 12
acute promyelocytic leukemia 11
prostate cancer 11
chronic myeloid leukemia 11
tumor progression 10
pseudoxanthoma elasticum 10
tumorigenesis 10
lung carcinoma 10
epilepsy 9
neutropenia 9
HIV 8
metastases 8
liver cancer 8
carcinogenesis 8
osteosarcoma 8
multiple myeloma 8
cystic fibrosis 8
childhood ALL 8
solid tumor 7
renal cell carcinoma 7
sarcoma 7
immunodeficiency 7
bladder cancer 6
stromal tumors 6
glioma 6
ABL 6
DDP 6
HCC 6
mitral valve prolapse 6
Melanoma 5
MMA 5
glioblastoma 4
myeloid leukemia 4
SCID 4
hypertension 4
dementia 4
Hepatocellular carcinoma 4
hyperbilirubinemia 4
asthma 4
myelodysplastic syndrome 4
stroke 4
diabetes 4
Dubin-Johnson syndrome 4
chronic obstructive pulmonary disease 4
acute leukemia 3
pancreatic cancer 3
erythroleukemia 3
tuberculosis 3
chronic lymphocytic leukemia 3
renal cancer 3
PML 3
glioblastoma multiforme 3
chronic lymphocytic leukemia 3
cirrhosis 3
genetic disorder 3
liver disease 3
hematologic malignancies 3
ATM 3
T-cell acute lymphoblastic leukemia 3
rheumatoid arthritis 3
cholestasis 3
anaplastic thyroid cancer 3
secondary AML 3
liver cancer 3
AIDS 3
retinoblastoma 3
Blocking 3
Colon cancer 3
thyroid cancer 2
Placenta 2
HAM 2
rhabdomyosarcoma 2
AS1 2
metastatic breast cancer 2
liposarcoma 2
adult ALL 2
Neuroblastoma 2
uterine sarcoma 2
peripheral neuropathy 2
Parkinson's disease 2
autism 2
schizophrenia 2
plaque 2
aggressiveness 2
autoimmune disease 2
WT1 2
non-Hodgkin's lymphoma 2
depression 2
Neuroblastoma 2
refractory cancer 2
synovial sarcoma 2
hypoglycemia 2
choriocarcinoma 2
gastrointestinal cancer 2
neurological disease 2
cognitive impairment 2
myopathy 2
obesity 2
hepatitis C 2
worms 2
XPD 2
Krabbe disease 2
PCS 2
NAME 2
acute tubular necrosis 2
chronic renal failure 2
minimal residual disease 2
lung disease 2
metabolic disorder 2
ischemia 2
residual disease 2
adult AML 2
multiple sclerosis 2
SDS 2
DMT1 2
laryngeal cancer 1
acromegaly 1
skin cancer 1
Kaposi's sarcoma 1
diphtheria 1
plasmacytoma 1
Chagas 1
malignant ascites 1
CCD 1
HIV disease progression 1
ureter 1
metastatic ovarian cancer 1
alcoholism 1
ADHD 1
blast crisis 1
uterus 1
Nonalcoholic fatty liver 1
LTD 1
uterine leiomyoma 1
more...
Symptom
diarrhea 3
seizures 2
starvation 1
asthenia 1
pain 1
spasticity 1
memory loss 1
hypothermia 1
hepatomegaly 1
bitter taste 1
splenomegaly 1
nausea and vomiting 1
Decreased activity 1
Drug
ABC 130
ADR 21
Glutathione 12
CPT-11 10
Adriamycin 9
CSF 5
Dermatol 5
Gleevec 4
ROS 4
VCR 4
VCR 4
Arsenic trioxide 4
Cremophor EL 4
Taxol 4
ADM 4
Adenosine triphosphate 4
Mutagen 2
Asthma 2
lysine 2
Etoposide 2
Bortezomib 2
Gefitinib 2
Irinotecan 2
Docetaxel 2
Imatinib 2
DM1 2
Sunitinib malate 2
PMEA 2
Ouabain 2
Pemetrexed 1
Vitamin K 1
Raloxifene 1
GEO 1
Olmesartan 1
Monit 1
Portal 1
TTC 1
balanced salt solution 1
AraC 1
Leaf 1
Fluorescein 1
EE2 1
Tariquidar 1
ROC 1
Acyclovir 1
Leucovorin 1
Indomethacin 1
G418 1
Vardenafil 1
AZT 1
Vitamin E 1
Gemfibrozil 1
DNase I 1
TAK 1
anti-CD33 1
THF 1
NovoSeven 1
Glycyrrhiza 1
AZT 1
Hectorol 1
Cobalamin 1
ampicillin 1
Asn 1
Azithromycin 1
MAP 1
Rutin 1
Fluorescein sodium 1
Salicylate 1
Vitamin B12 1
Itraconazole 1
ascorbate 1
Ranitidine 1
EPI 1
Budesonide 1
Alanine 1
Emodin 1
Alimta 1
Emodin 1
Primaquine 1
Sorafenib 1
IFN-gamma 1
NBT 1
Taxotere 1
NVP 1
Ginger 1
Gel 1
Flavopiridol 1
Cetuximab 1
Compound 9 1
Enzyme
P-glycoprotein 335
ATPase 75
MDR 35
topoisomerase 29
glutathione S-transferase 27
topoisomerase 25
ERK 22
luciferase 19
CYP3A4 17
reverse transcriptase 15
focal adhesion kinase 14
mitogen-activated protein kinase 13
gamma-glutamylcysteine synthetase 10
RNase 9
protein kinase 9
RNase 9
caspase-3 8
UDP-glucuronosyltransferase 7
thymidylate synthase 6
lactate dehydrogenase 5
deoxycytidine kinase 5
phosphodiesterase 5
catalase 5
phosphatidylinositol 3-kinase 5
ACS 4
glyceraldehyde-3-phosphate dehydrogenase 4
LTA4 hydrolase 4
protein kinase C 4
glutathione reductase 4
transcriptase 4
RNA polymerase 4
glutathione peroxidase 4
trypsin 4
sphingosine kinase 3
folylpolyglutamate synthetase 3
IKK 3
PARP 3
NQO1 3
dihydropyrimidine dehydrogenase 3
dihydropyrimidine dehydrogenase 3
MEK 2
cysteine synthase 2
asparaginase 2
phosphoglycerate kinase 2
superoxide dismutase 2
phospholipase C 2
phospholipase A2 2
adenosine deaminase 2
adenosine deaminase 2
Mg2+-ATPase 2
HIV-1 protease 2
proteasome 2
5'-nucleotidase 1
neuraminidase 1
guanylate cyclase 1
chalcone synthase 1
protein phosphatase 2A 1
ATP synthase 1
carboxylesterase 1
chymotrypsin 1
glyceraldehyde-3-phosphate dehydrogenase 1
beta-secretase 1
PAL 1
APC 1
aldose reductase 1
biliverdin reductase 1
ribonuclease 1
alanine aminotransferase 1
endoglycosidase H 1
Pla 1
caspase-9 1
CD10 1
ALDH 1
PDE 1
histidine permease 1
glyceraldehyde-3-phosphate dehydrogenase 1
phospholipase D 1
deoxyguanosine kinase 1
mu-calpain 1
CEP 1
collagenase 1
matrix metalloproteinase 9 1
hyaluronidase 1
firefly luciferase 1
arachidonate 5-lipoxygenase 1
glucose-6-phosphate dehydrogenase 1
ribonuclease 1
glyceraldehyde-3-phosphate dehydrogenase 1
peroxiredoxin 1
hyaluronidase 1
acetylcholinesterase 1
heme oxygenase 1
N-acetylglucosaminyltransferase 1
deoxycytidine deaminase 1
LTC4 synthase 1
hypoxanthine-guanine phosphoribosyltransferase 1
PNGase F 1
insulin-degrading enzyme 1
thioredoxin reductase 1
glyceraldehyde-3-phosphate dehydrogenase 1
bile salt hydrolase 1
thymidine kinase 1
oxidosqualene cyclase 1
GSK 1
renin 1
PAL 1
CYP46A1 1
3beta-hydroxysteroid dehydrogenase 1
alkaline phosphatase 1
gamma-glutamyl transpeptidase 1
CEP 1
carbonyl reductase 1
serine acetyltransferase 1
DNA polymerase 1
dihydrodiol dehydrogenase 1
aspartate aminotransferase 1
succinate dehydrogenase 1
Compound
ATP 165
Dec 89
GSH 80
GSH 80
DNA 79
MTT 44
Clin 37
MDR 35
sulfate 29
ADR 29
SN-38 21
sodium 21
oxygen 19
phosphate 19
Adriamycin 18
VP-16 16
MDA 15
LTC4 15
bromide 13
cadmium 13
Hoechst 33342 12
alanine 11
water 11
DDP 11
CPT-11 10
Paclitaxel 10
diacetate 10
calcium 9
ADP 8
ADP 8
cysteine 8
ADP 8
potassium 8
pyrene 8
GSSG 8
BCR 7
Vinca 7
ABL 7
tyrosine 6
Verapamil 6
BSO 6
galactose 6
Curcumin 6
cGMP 6
Verapamil 6
iron 6
MMA 5
pyrimidine 5
ethanol 5
salt 5
lysine 5
MMA 5
MMA 5
chalcone 5
tryptophan 5
tryptophan 5
glucose 5
Probenecid 5
tryptophan 5
threonine 5
pyrimidine 5
tryptophan 5
DNP 5
cAMP 5
quinoline 5
UDP 5
PEG 4
quinoline 4
PEG 4
DMA 4
Genistein 4
Gemcitabine 4
selenium 4
dimethylarsinic acid 4
dimethylarsinic acid 4
nitric oxide 4
His 4
dimethylarsinic acid 4
Rhodamine 123 4
kaempferol 4
copper 4
ACS 4
nitrogen 4
Arsenic 4
DMA 4
5-FU 4
dimethylarsinic acid 4
Gemcitabine 4
dimethylarsinic acid 4
uridine 4
DMA 4
ACS 4
dimethylarsinic acid 4
Vincristine 4
Phe 3
Rifampicin 3
Methotrexate 3
leucine 3
ACNU 3
isoxazole 3
Mitoxantrone 3
AMP 3
Daunorubicin 3
TNF 3
serine 3
PGA 3
APAP 3
Cyclosporine 3
N-acetylcysteine 3
mercury 3
retinoic acid 3
urea 3
cyanide 3
hydrogen 3
Rhodamine B 3
Mitoxantrone 3
2-nonenal 3
acridine 3
pyridine 3
quinazoline 2
dUTP 2
Ouabain 2
NH2 2
iodine 2
methionine 2
FK506 2
PMEA 2
CAT 2
CAT 2
glutamic acid 2
Asp 2
MTS 2
chrysene 2
hexadecyl 2
creatinine 2
ZD1694 2
CAT 2
1-chloro-2,4-dinitrobenzene 2
1-butanol 2
propionic acid 2
vitamin D 2
decyl 2
Docetaxel 2
aldehyde 2
Optimal 2
vinyl 2
Fluo-3 2
Sphingosine 2
Daunomycin 2
GM1 2
Gly 2
MES 2
propionic acid 2
Pac 2
CTP 2
MEK 2
zinc 2
MES 2
decyl 2
Sphingosine 1-phosphate 2
more...