Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P31749 (AKT)
 22,954 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AKT 1.000
PI3K 0.104
mTOR 0.032
protein kinase B 0.016
ERK 0.015
PTEN 0.013
AKT1 0.008
MAPK 0.006
ERK1 0.006
phosphoinositide 3-kinase 0.005
phosphatidylinositol 3-kinase 0.005
PIK3CA 0.004
phosphatase and tensin homolog 0.003
AKT2 0.003
PKB 0.003
MEK 0.003
EGFR 0.002
RAF 0.002
GSK 0.002
STAT3 0.002
AKT3 0.002
caspase-3 0.001
JNK 0.001
p38 0.001
PI3 0.001
PDK1 0.001
IRS-1 0.001
Bcl-2 0.001
catenin 0.001
epidermal growth factor receptor 0.001
4EBP1 0.001
S6K1 0.001
P70S6K 0.001
extracellular signal-regulated kinase 0.001
AMPK 0.001
FAK 0.001
cyclin D1 0.001
p53 0.001
serine/threonine kinase 0.001
BAD 0.001
RICTOR 0.001
4E-BP1 0.001
tensin 0.001
KRAS 0.001
PARP 0.001
HER2 0.001
HER3 0.001
BRAF 0.001
MET 0.001
STAT 0.001
FOXO3 0.001
LC3 0.001
ERBB3 0.001
tyrosine kinase 0.001
VEGF 0.001
ERBB 0.001
receptor tyrosine kinase 0.001
Mol 0.001
P38 0.001
E-cadherin 0.001
PIK3 0.001
ribosomal protein S6 0.001
IGF1R 0.001
insulin 0.001
GSK3 0.001
rhabdomyosarcoma 0.000
Mcl-1 0.000
Phosphatase and tensin homolog 0.000
p27 0.000
CDK4 0.000
PIK3R1 0.000
STAT5 0.000
PIK3R2 0.000
SRC 0.000
focal adhesion kinase 0.000
p21 0.000
vascular endothelial growth factor 0.000
PIP3 0.000
MEK1 0.000
IGF-1 0.000
more...
Disease
cancer 0.003
tumor 0.002
tumor growth 0.002
tumorigenesis 0.001
breast cancer 0.001
tumor progression 0.001
hepatocellular carcinoma 0.001
non-small cell lung cancer 0.001
prostate cancer 0.000
lung cancer 0.000
glioma 0.000
colorectal cancer 0.000
glioblastoma 0.000
EMT 0.000
ovarian cancer 0.000
carcinogenesis 0.000
gastric cancer 0.000
MCF 0.000
melanoma 0.000
pancreatic cancer 0.000
colon cancer 0.000
Hepatocellular carcinoma 0.000
carcinoma 0.000
tumor angiogenesis 0.000
liver cancer 0.000
B-cell lymphoma 0.000
adenocarcinoma 0.000
squamous cell carcinoma 0.000
osteosarcoma 0.000
endometrial cancer 0.000
liver cancer 0.000
DDP 0.000
leukemia 0.000
Osteosarcoma 0.000
Osteosarcoma 0.000
Glioblastoma 0.000
glioblastoma multiforme 0.000
acute myeloid leukemia 0.000
aggressiveness 0.000
T-cell acute lymphoblastic leukemia 0.000
epithelial ovarian cancer 0.000
HGF 0.000
AGS 0.000
thyroid cancer 0.000
Blocking 0.000
Proteus syndrome 0.000
bladder cancer 0.000
ABL 0.000
metastases 0.000
Multiple Lentigines 0.000
SHORT syndrome 0.000
cervical cancer 0.000
tumor initiation 0.000
Melanoma 0.000
tuberous sclerosis 0.000
renal cell carcinoma 0.000
type 2 diabetes 0.000
multiple myeloma 0.000
Esophageal squamous cell carcinoma 0.000
diabetes 0.000
anaplastic thyroid cancer 0.000
obesity 0.000
retinoblastoma 0.000
lymphoma 0.000
hyperglycemia 0.000
neuroblastoma 0.000
HCC 0.000
brain tumor 0.000
metastatic melanoma 0.000
AS1 0.000
mantle cell lymphoma 0.000
ATM 0.000
MTS 0.000
ischemia 0.000
chronic myeloid leukemia 0.000
Cowden syndrome 0.000
chronic lymphocytic leukemia 0.000
metastatic follicular thyroid cancer 0.000
Thyroid cancer 0.000
Neuroblastoma 0.000
more...
Symptom
starvation 0.000
functional recovery 0.000
Mucosal hyperplasia 0.000
Scratch 0.000
difficulty with urination 0.000
finger pain 0.000
cachexia 0.000
musculoskeletal disability 0.000
memory loss 0.000
exhaustion 0.000
Motor dysfunction 0.000
skin damage 0.000
seizures 0.000
splenomegaly 0.000
stomach pain 0.000
fatigue 0.000
impaired motor coordination 0.000
pelvic pain 0.000
pain 0.000
hyperoxia 0.000
urinary frequency 0.000
collapse 0.000
diarrhea 0.000
respiratory distress 0.000
weakness 0.000
hepatomegaly 0.000
cancer pain 0.000
decreased appetite 0.000
ataxia 0.000
swollen joints 0.000
ataxic gait 0.000
halitosis 0.000
thinning 0.000
overweight 0.000
acute stress 0.000
nausea 0.000
incoordination 0.000
hypothermia 0.000
Depressive symptoms 0.000
hypotonia 0.000
skin irritation 0.000
acute pain 0.000
Stiffness 0.000
bradykinesia 0.000
microbial colonization 0.000
hot flashes 0.000
low back pain 0.000
anorexia 0.000
dry eye 0.000
wheezing 0.000
anesthesia 0.000
knee pain 0.000
chronic constipation 0.000
bone pain 0.000
Neuropathic pain 0.000
despair 0.000
menopausal symptoms 0.000
enuresis 0.000
arthralgia 0.000
chronic cough 0.000
leg pain 0.000
acidity 0.000
constipation 0.000
masculinization 0.000
vomiting 0.000
cough 0.000
asthenia 0.000
paraparesis 0.000
sore throat 0.000
myalgia 0.000
agitation 0.000
dyspnea 0.000
analgesia 0.000
ophthalmoplegia 0.000
epigastric pain 0.000
hypercapnia 0.000
cerebellar ataxia 0.000
neck pain 0.000
chills 0.000
nausea and vomiting 0.000
more...
Drug
NVP 0.000
ROS 0.000
Gefitinib 0.000
Everolimus 0.000
Sorafenib 0.000
Cetuximab 0.000
Herceptin 0.000
Efipladib 0.000
Caprylic Acid 0.000
Erlotinib 0.000
Canertinib dihydrochloride 0.000
MAP 0.000
Dasatinib 0.000
Epigallocatechin 0.000
3-Methyladenine 0.000
GEO 0.000
RAL 0.000
Tarceva 0.000
Imatinib 0.000
Epimedium herb 0.000
Emodin 0.000
Bupleurum root 0.000
Purvalanol 0.000
Vandetanib 0.000
uPA 0.000
Arsenic trioxide 0.000
Monit 0.000
Emodin 0.000
Zedoary 0.000
Romidepsin 0.000
Tykerb 0.000
Bosutinib 0.000
Insulin glulisine 0.000
Casodex 0.000
Gleevec 0.000
Fenobam 0.000
Romet 0.000
Bortezomib 0.000
Atractylodes rhizome 0.000
Medalist 0.000
p75 0.000
Pertuzumab 0.000
Glycyrrhiza 0.000
Benzofuran 0.000
IL-2 0.000
Rosiglitazone 0.000
Simvastatin 0.000
Ferric ammonium citrate 0.000
Tobi 0.000
Pirarubicin 0.000
lysine 0.000
Tanespimycin 0.000
Bindarit 0.000
Myricetin 0.000
Pemetrexed 0.000
Sodium dichloroacetate 0.000
Alarin 0.000
Sodium Nitroprusside 0.000
Nexavar 0.000
Liraglutide 0.000
ICI 0.000
Avobenzone 0.000
ADR 0.000
Atazanavir sulfate 0.000
Berberine chloride 0.000
Vorinostat 0.000
Sesamol 0.000
Fidarestat 0.000
Fidarestat 0.000
Safflower 0.000
ETS 0.000
Polaprezinc 0.000
Nelarabine 0.000
CCL 0.000
Vinpocetine 0.000
Lipitor 0.000
TTC 0.000
NLF 0.000
RFP 0.000
Glucagon 0.000
more...
Enzyme
mitogen-activated protein kinase 0.011
ERK 0.010
phosphoinositide 3-kinase 0.005
phosphatidylinositol 3-kinase 0.005
MEK 0.003
focal adhesion kinase 0.002
GSK 0.002
AMPK 0.001
AMP-activated protein kinase 0.001
PDK1 0.001
caspase-3 0.001
protein kinase 0.001
PARP 0.001
AMPK 0.001
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
luciferase 0.000
caspase-9 0.000
inositol 3-kinase 0.000
TOR 0.000
IKK 0.000
protein kinase C 0.000
HK2 0.000
proteasome 0.000
calcineurin 0.000
caspase-8 0.000
protein phosphatase 2A 0.000
cdc2 0.000
MAP 0.000
superoxide dismutase 0.000
NADPH oxidase 0.000
MMP 0.000
NADPH oxidase 0.000
STK11 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 0.000
caspase-7 0.000
caspase-7 0.000
inositol polyphosphate 4-phosphatase 0.000
AMP-activated kinase 0.000
MPP 0.000
matrix metalloproteinase 2 0.000
STK13 0.000
sphingosine kinase 0.000
MEKK1 0.000
catalase 0.000
lactate dehydrogenase 0.000
matrix metalloproteinase 9 0.000
P-glycoprotein 0.000
urokinase-type plasminogen activator 0.000
glucose-6-phosphatase 0.000
cathepsin K 0.000
acetyl-CoA carboxylase 0.000
heme oxygenase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
GRK2 0.000
phosphatidylinositol 3-phosphate 5-kinase 0.000
prenylated protein methyltransferase 0.000
ALDH 0.000
polo-like kinase 1 0.000
matrix metalloproteinase 14 0.000
MMP-3 0.000
CaMKII 0.000
hormone-sensitive lipase 0.000
DCF 0.000
BCKDH 0.000
phospholipase C 0.000
collagenase 0.000
PKG 0.000
tyrosinase 0.000
MGAT 0.000
proteinase-3 0.000
ATPase 0.000
PLP phosphatase 0.000
D-dopachrome tautomerase 0.000
NO synthase 0.000
alkaline phosphatase 0.000
NQO1 0.000
alanine aminotransferase 0.000
aspartate aminotransferase 0.000
more...
Compound
MEK 0.003
MTT 0.001
MDA 0.000
Phosphatidylinositol 0.000
tyrosine 0.000
glucose 0.000
Rapamycin 0.000
TNF 0.000
oxygen 0.000
Vimentin 0.000
serine 0.000
threonine 0.000
Insulin 0.000
Wortmannin 0.000
DNA 0.000
DDP 0.000
TNM 0.000
methionine 0.000
TSC 0.000
BCR 0.000
Metformin 0.000
Metformin 0.000
C20H21NO5 0.000
Chelerythrine hydrochloride 0.000
C20H21NO5 0.000
C20H21NO5 0.000
Plantamajoside 0.000
C20H21NO5 0.000
C20H21NO5 0.000
C20H21NO5 0.000
ABL 0.000
dUTP 0.000
Bruceine D 0.000
Tamarixetin 0.000
Shikonin 0.000
Resveratrol 0.000
MTS 0.000
MAP 0.000
LY 294002 0.000
C14H16N2O4S 0.000
C16H20O5 0.000
C19H18O7 0.000
Gentisyl alcohol 0.000
C21H20N2O2 0.000
C16H12O4 0.000
Jervine 0.000
Deguelin 0.000
4-Bromodiphenyl ether 0.000
4-Bromodiphenyl ether 0.000
Deltonin 0.000
Farrerol 0.000
Dec 0.000
ATP 0.000
Garcinol 0.000
Temsirolimus 0.000
Sinulariolide 0.000
cAMP 0.000
Matrine 0.000
Matrine 0.000
Matrine 0.000
Eurycomalactone 0.000
Columbamine 0.000
Papaverinol 0.000
Selenocystine 0.000
Spectinabilin 0.000
Galangin 0.000
N-acetylcysteine 0.000
Bufalin 0.000
Curcumin 0.000
Cyclovirobuxine D 0.000
3-Methyladenine 0.000
Luteolin 0.000
Ailanthone 0.000
Apigetrin 0.000
cyclohexyl salicylate 0.000
Auriculasin 0.000
Heterophyllin 0.000
furostan-3,26-diol 0.000
2-acetyl-1,3-cyclopentanedione 0.000
3-fluorobenzamide 0.000
more...