Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P31749 (AKT)
 22,954 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

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Human Gene/Protein
solute carrier family 3, member 1 10.4
WD repeat domain 13 10.4
mitochondrial ribosomal protein S16 10.4
enolase-phosphatase 1 10.4
SPIN3 10.4
Transforming growth factor beta regulator 4 10.4
WD repeat and FYVE domain containing 2 10.4
MER receptor tyrosine kinase 10.4
MRIP-1 10.4
Ubiquitin specific peptidase 49 10.4
TCF2 protein 10.4
RUN and FYVE domain containing 1 10.4
SPECC1L protein 10.4
XKR5 10.4
SNF related kinase 10.4
SH2B3 protein 10.4
CNN2 protein 10.4
C1orf54 10.4
mitogen-activated protein kinase kinase kinase kinase 2 10.4
HNF4G protein 10.4
VRK2 protein 10.4
six-transmembrane epithelial antigen of prostate 2 10.4
G protein-coupled receptor 107 10.4
Pre-B-cell leukemia homeobox interacting protein 1 10.4
anaphase-promoting complex subunit 7 10.4
JMJD7-PLA2G4B 10.4
CRISPLD1 10.4
EIF3EIP protein 10.4
Basic leucine zipper and W2 domains 2 10.4
PI4KAP2 10.4
LONRF2 10.4
ANKRD39 10.4
jumonji domain containing 7 10.4
AKT 10.4
AMPH1 10.4
partner of NOB1 10.4
Polypeptide N-acetylgalactosaminyltransferase 6 10.4
proline rich 5 10.4
THUMP domain-containing protein 1 10.4
Serine incorporator 2 10.4
AKT3 protein 10.0
WD repeat domain 41 9.9
Transmembrane protein 98 9.9
HCRP1 9.7
EVI5L 9.4
v-src sarcoma 9.4
G5c 9.4
S100 calcium binding protein A16 9.4
Alpha-2,8-sialyltransferase 9.4
Inositol polyphosphate-5-phosphatase F 9.4
SH3GL2 protein 9.4
ZFX protein 9.4
tripartite motif-containing 31 9.4
Smith-Magenis syndrome chromosome region, candidate 8 9.4
AKT interacting protein 9.4
mitochondrial ubiquitin ligase activator of NFKB 1 9.4
Starch-binding domain-containing protein 1 9.4
Endothelial nitric oxidase synthase 9.4
Growth factor receptor-bound protein 7 9.4
ENC-1AS 9.4
Tumor necrosis factor alpha induced protein 3 9.4
KIAA1212 9.4
MAPK1IP1L 9.4
immunglobulin heavy chain 9.4
PIK3R2 protein 9.4
GRAMD1C 9.4
FUNDC2 9.4
kelch repeat and BTB (POZ) domain containing 7 9.4
G1/S-specific cyclin E2 9.4
mitogen-activated protein kinase associated protein 1 9.4
SGK494 9.4
ZCCHC13 9.4
Zinc finger X-chromosomal protein 9.4
P55PIK 9.4
sperm autoantigenic protein 17 9.4
NEDD4L variant 9.4
neuron navigator 1 9.4
transmembrane protein 93 9.4
thyroid adenoma associated 9.4
OR14I1 9.4
more...
Disease
Multiple Lentigines 9.4
Keratocystic Odontogenic Tumor 8.1
ADMD 8.1
Alcoholic liver damage 8.1
SHORT syndrome 8.1
pre-T LBL 7.9
metastatic follicular thyroid cancer 7.8
T Cell Leukemia 7.6
phakoma 7.3
Endocrine pancreas 7.1
Endocrine pancreas 7.1
CLL transformation 7.0
High altitude cerebral edema 6.9
Neonatal necrotizing enterocolitis 6.7
DA5 6.6
childhood ependymoma 6.6
Diabetic gastroparesis 6.6
Proteus syndrome 6.5
Gastrointestinal mucositis 6.5
CEBPG 6.5
muscle cancer 6.4
refractory CML 6.4
RP17 6.4
Papillary Thyroid Carcinoma 6.3
HER-2 positive breast cancer 6.2
Ruvalcaba syndrome 6.2
Progression of prostate cancer 6.1
EMT 6.1
Baraitser-Winter syndrome 6.0
Hepatocarcinogenesis 6.0
metastatic parathyroid carcinoma 6.0
Anaplastic Lymphoma 6.0
IBMPFD 5.9
CMT4B1 5.9
bone marrow cancer 5.9
Trichoblastoma 5.9
adult brain tumor 5.9
Intrauterine adhesions 5.9
pediatric solid tumor 5.9
Posterior capsule opacification 5.9
recurrent endometrial cancer 5.8
Silence 5.8
metastatic endometrial cancer 5.8
WM1 5.8
GCB-DLBCL 5.7
anaplastic thyroid cancer 5.7
PanIN-1 5.7
Cowden syndrome 5.7
cancer angiogenesis 5.6
RP6 5.6
PNKD 5.6
FHL2 5.6
PanIN-3 5.6
accelerated phase CML 5.6
neck neoplasm 5.6
Juvenile granulosa cell tumor 5.6
Tumor morphology 5.6
relapsed CML 5.6
Gallbladder carcinoma 5.6
Costello syndrome 5.5
Osteosarcoma 5.5
Osteosarcoma 5.5
pituitary cancer 5.5
Malignant glioma 5.5
PanIN 5.5
Mesangial proliferative glomerulonephritis 5.4
Eosinophilic colitis 5.4
Philadelphia chromosome positive chronic myelogenous leukemia 5.4
LEOPARD syndrome 5.4
Hypothalamic dysfunction 5.4
PARK7 5.4
Myxoid liposarcoma 5.4
Esophageal squamous cell carcinoma 5.4
tumor growth 5.3
Disuse atrophy 5.3
AGS 5.3
Glioblastoma 5.3
T-cell acute lymphoblastic leukemia 5.3
Malignant pheochromocytoma 5.3
Obstructive nephropathy 5.3
more...
Symptom
Mucosal hyperplasia 6.2
difficulty with urination 5.7
finger pain 5.2
musculoskeletal disability 4.9
Scratch 4.6
Motor dysfunction 4.1
stomach pain 3.1
impaired motor coordination 2.9
starvation 2.8
skin damage 2.7
cachexia 2.5
memory loss 2.4
functional recovery 2.4
urinary frequency 1.9
pelvic pain 1.5
swollen joints 1.4
exhaustion 1.3
ataxic gait 1.3
hyperoxia 1.3
splenomegaly 1.3
decreased appetite 1.2
halitosis 1.2
cancer pain 0.9
incoordination 0.6
hepatomegaly 0.5
Stiffness 0.5
Depressive symptoms 0.5
microbial colonization 0.4
hot flashes 0.4
skin irritation 0.4
acute stress 0.3
bradykinesia 0.2
chronic constipation 0.1
dry eye 0.1
acute pain 0.1
seizures -0.0
knee pain -0.0
Neuropathic pain -0.0
hypotonia -0.1
collapse -0.1
respiratory distress -0.1
bone pain -0.2
ataxia -0.2
wheezing -0.2
thinning -0.2
despair -0.2
fatigue -0.2
menopausal symptoms -0.2
enuresis -0.2
low back pain -0.5
chronic cough -0.6
leg pain -0.6
weakness -0.6
diarrhea -0.6
hypothermia -0.6
anorexia -0.7
nausea -0.8
arthralgia -0.8
overweight -0.8
masculinization -0.9
asthenia -0.9
paraparesis -1.0
sore throat -1.0
myalgia -1.2
ophthalmoplegia -1.3
constipation -1.3
epigastric pain -1.3
cerebellar ataxia -1.4
pain -1.4
acidity -1.5
neck pain -1.5
hypercapnia -1.5
agitation -1.5
chills -1.6
hepatosplenomegaly -1.7
cough -1.8
nausea and vomiting -1.8
ENT -1.9
vomiting -1.9
dyspnea -2.0
more...
Drug
Caprylic Acid 10.4
Efipladib 9.4
Canertinib dihydrochloride 8.9
Epimedium herb 7.6
Bupleurum root 7.3
Zedoary 7.1
NVP 7.1
Purvalanol 6.9
Everolimus 6.6
Romet 6.4
Fenobam 6.4
Insulin glulisine 6.4
3-Methyladenine 6.4
Gefitinib 6.3
Atractylodes rhizome 6.3
Medalist 6.3
Tykerb 6.2
Cetuximab 6.1
Tobi 6.0
Ferric ammonium citrate 6.0
RAL 6.0
Tarceva 6.0
Vandetanib 5.9
Romidepsin 5.9
Sorafenib 5.9
Bindarit 5.9
Tanespimycin 5.9
Bosutinib 5.9
Benzofuran 5.9
Sodium dichloroacetate 5.9
Sodium Nitroprusside 5.8
Avobenzone 5.7
Epigallocatechin 5.7
Atazanavir sulfate 5.7
Berberine chloride 5.7
Fidarestat 5.6
Fidarestat 5.6
Alarin 5.6
Erlotinib 5.5
Dasatinib 5.5
Pirarubicin 5.5
Polaprezinc 5.5
Casodex 5.4
Nelarabine 5.4
Pertuzumab 5.4
Herceptin 5.4
Nexavar 5.3
Emodin 5.3
Sesamol 5.2
Azilect 5.1
Safflower 5.1
Lipitor 5.1
Amlexanox 5.0
Emodin 5.0
Insulin aspart 4.9
Darifenacin 4.9
Avandia 4.9
GEO 4.8
Vinpocetine 4.8
1-Deoxynojirimycin 4.8
Myricetin 4.8
NLF 4.7
ROS 4.7
Tianma 4.7
Humalog 4.7
Epidoxorubicin 4.7
Lipitor 4.6
Lipitor 4.6
Swainsonine 4.6
Pemetrexed 4.6
Levitra 4.6
Red ginseng 4.6
Vorinostat 4.6
Fluphenazine 4.5
Ebastine 4.5
Liraglutide 4.5
Amlodipine besylate 4.5
Arsenic trioxide 4.4
Roflumilast 4.4
Roflumilast 4.4
more...
Enzyme
phosphatidylinositol-4,5-bisphosphate 3-kinase 8.2
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 7.9
phosphoinositide 3-kinase 7.7
STK13 7.3
inositol 3-kinase 7.2
PDK1 7.1
phosphatidylinositol 3-kinase 7.1
inositol polyphosphate 4-phosphatase 6.9
GSK 6.7
AMPK 6.5
prenylated protein methyltransferase 6.4
phosphatidylinositol 3-phosphate 5-kinase 6.4
MEK 6.4
HK2 6.4
mitogen-activated protein kinase 6.2
ERK 6.1
BCKDH 5.9
TOR 5.9
AMP-activated protein kinase 5.9
MGAT 5.7
PLP phosphatase 5.7
focal adhesion kinase 5.6
STK11 5.6
matrix metalloproteinase 14 5.6
PARP 5.5
AMPK 5.5
D-dopachrome tautomerase 5.4
matrix metalloproteinase 10 5.3
AMP-activated kinase 5.3
caspase-9 5.2
isochorismatase 5.2
fucokinase 5.1
caspase-3 5.1
chondroitin 6-sulfotransferase 5.1
STK4 5.0
IKK 5.0
GK2 5.0
caspase-7 5.0
cholesterol 25-hydroxylase 4.9
caspase-7 4.9
protein phosphatase 2A 4.9
CMP-Neu5Ac hydroxylase 4.9
sphingosine kinase 4.8
acylglycerol kinase 4.7
ceramide kinase 4.7
site-1 protease 4.6
site-1 protease 4.6
proteinase-3 4.6
phosphofructokinase 1 4.6
protein kinase 4.5
pantothenate synthetase 4.5
GRK2 4.4
luciferase 4.3
ALDH 4.3
caspase-8 4.3
MPP 4.3
GalT 4.3
hepsin 4.2
hepsin 4.2
malonyl-CoA decarboxylase 4.2
lysophospholipase D 4.2
STK 4.2
matrix metalloproteinase 2 4.2
MEKK1 4.2
MAP 4.1
cdc2 4.1
MMP 4.1
STK3 4.0
cathepsin K 4.0
pyruvate dehydrogenase phosphatase 4.0
CYP8B1 3.9
matrix metalloproteinase 9 3.9
STK2 3.9
phosphoenolpyruvate carboxykinase 3.9
GD3 synthase 3.9
polo-like kinase 1 3.9
3-oxoacid CoA-transferase 3.8
hydroxyprostaglandin dehydrogenase 3.8
glycerol-3-phosphate oxidase 3.8
dynamin GTPase 3.7
more...
Compound
C20H21NO5 10.4
C20H21NO5 10.4
C20H21NO5 10.4
C20H21NO5 10.4
C20H21NO5 10.4
Chelerythrine hydrochloride 10.4
C20H21NO5 10.4
C16H12O4 9.4
C16H20O5 9.4
Gentisyl alcohol 9.4
4-Bromodiphenyl ether 9.4
C14H16N2O4S 9.4
C19H18O7 9.4
C21H20N2O2 9.4
4-Bromodiphenyl ether 9.4
Spectinabilin 8.9
Eurycomalactone 8.9
Tamarixetin 8.9
Columbamine 8.9
Papaverinol 8.9
Plantamajoside 8.7
Jervine 8.6
Deltonin 8.6
Deuterohemin 8.4
Heterophyllin 8.4
furostan-3,26-diol 8.4
2-acetyl-1,3-cyclopentanedione 8.4
3-fluorobenzamide 8.4
cyclohexyl salicylate 8.4
Dihydrorotenone 8.4
Deuterohemin 8.4
Bruceine D 8.4
C16H14O3 8.4
Auriculasin 8.4
Sinulariolide 8.3
C19H18O3 8.1
2,2',4,4',5,5'-Hexachlorobiphenyl 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
Mahanimbine 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
Cyclovirobuxine D 8.1
Astragaloside III 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
C19H18O3 8.1
Apigetrin 8.0
Rutamarin 7.9
Farrerol 7.9
Vasicinone 7.9
Aplysin 7.9
C19H18O3 7.9
Carlina oxide 7.9
5-Methoxytryptophan 7.9
C19H18O3 7.9
Maclurin 7.9
Ailanthone 7.6
C19H18O3 7.6
Eupatolide 7.6
Virosecurinine 7.6
Hydrangenol 7.6
Glycitin 7.6
Pachymic acid 7.6
Guaiol 7.6
Ovatodiolide 7.5
C19H18O3 7.4
Panaxatriol 7.4
Ailanthone 7.4
Selenocystine 7.3
Girinimbine 7.3
Coumarin 30 7.3
more...