Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UNIPROT:P31749 (AKT)
22,954 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein AKT 22954 PI3K 7483 mTOR 4378 ERK 2995 Mol 2804 MAPK 2051 ERK1 1697 PTEN 1635 insulin 1587 protein kinase B 1586 Sep 1364 caspase-3 1253 p53 1250 phosphatidylinositol 3-kinase 1094 Bcl-2 973 p38 955 MEK 926 phosphoinositide 3-kinase 857 EGFR 813 epidermal growth factor receptor 812 JNK 730 catenin 725 STAT3 710 tyrosine kinase 691 cytokine 582 TNF 562 extracellular signal-regulated kinase 562 vascular endothelial growth factor 530 cyclin D1 527 AKT1 523 PIK3CA 519 GSK 501 phosphatase 493 IL-6 482 VEGF 460 p21 444 HER2 441 PKB 435 E-cadherin 432 phosphatase and tensin homolog 420 more...

Disease cancer 8026 tumor 6137 breast cancer 1715 tumor growth 1685 tumorigenesis 1388 hepatocellular carcinoma 928 tumor progression 804 lung cancer 781 carcinoma 764 prostate cancer 723 carcinogenesis 651 colorectal cancer 629 melanoma 605 diabetes 582 non-small cell lung cancer 516 glioma 499 leukemia 495 adenocarcinoma 492 gastric cancer 472 ovarian cancer 432 metastases 398 MCF 389 squamous cell carcinoma 386 colon cancer 383 obesity 382 glioblastoma 366 pancreatic cancer 326 ischemia 294 lymphoma 285 acute myeloid leukemia 278 type 2 diabetes 270 B-cell lymphoma 245 Alzheimer's disease 240 liver cancer 235 osteosarcoma 233 multiple myeloma 212 endometrial cancer 181 hyperglycemia 179 cervical cancer 178 liver cancer 176 more...

Symptom starvation 127 pain 70 seizures 57 functional recovery 50 fatigue 32 diarrhea 27 exhaustion 25 cachexia 23 collapse 19 anesthesia 18 weakness 18 splenomegaly 17 memory loss 14 respiratory distress 13 overweight 11 ataxia 10 nausea 10 hyperoxia 9 pelvic pain 8 hypothermia 8 Scratch 7 skin damage 7 thinning 7 hepatomegaly 6 anorexia 6 vomiting 6 low back pain 5 dyspnea 5 analgesia 5 cough 5 hypotonia 4 acute stress 4 cancer pain 4 acidity 4 acute pain 3 arthralgia 3 wheezing 3 urinary frequency 3 abdominal pain 3 constipation 3 more...

Drug ROS 359 Monit 109 MAP 109 lysine 99 NVP 97 Dermatol 80 IL-2 71 Herceptin 69 Gefitinib 68 Sorafenib 66 Everolimus 50 Cetuximab 47 CSF 41 Imatinib 34 GEO 32 ICI 27 uPA 26 p75 26 Erlotinib 25 Cardiovasc 24 CAM 22 ABC 21 Dasatinib 20 Arsenic trioxide 20 Glucagon 18 Gleevec 18 EE2 18 Bortezomib 17 ETS 17 Epigallocatechin 17 vitamin E 17 Simvastatin 16 Taxol 16 ADR 16 Adriamycin 15 Glycyrrhiza 15 NADH 15 ascorbate 14 Angiotensin II 14 Heme 13 more...

Enzyme mitogen-activated protein kinase 4957 ERK 4790 focal adhesion kinase 1584 protein kinase 1331 MEK 1116 phosphatidylinositol 3-kinase 1094 caspase-3 884 phosphoinositide 3-kinase 857 luciferase 560 AMP-activated protein kinase 559 GSK 524 PARP 455 AMPK 408 AMPK 401 protein kinase C 350 proteasome 232 PDK1 223 superoxide dismutase 202 caspase-9 199 calcineurin 164 catalase 127 IKK 112 cdc2 105 caspase-8 99 MAP 94 ATPase 94 lactate dehydrogenase 91 NADPH oxidase 86 NADPH oxidase 80 alkaline phosphatase 77 protein phosphatase 2A 65 TOR 64 P-glycoprotein 60 peroxidase 58 alanine aminotransferase 55 phospholipase C 53 urokinase-type plasminogen activator 53 collagenase 52 MMP 52 phosphoenolpyruvate carboxykinase 50 more...

Compound DNA 1444 Dec 1421 glucose 1336 oxygen 1220 MEK 910 tyrosine 761 MTT 719 TNF 562 Clin 522 serine 466 MDA 433 calcium 390 threonine 373 ATP 348 methionine 336 Insulin 283 nitric oxide 247 water 243 phosphate 222 cAMP 217 sodium 178 hydrogen 156 cysteine 153 bromide 149 Phosphatidylinositol 141 TNM 135 DDP 133 Rapamycin 133 iodine 131 lysine 128 AMP 117 GSH 116 GSH 116 acetate 100 arginine 100 BCR 98 MAP 97 dUTP 97 glutamate 96 Vimentin 96 more...

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