Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P31749 (AKT)
22,954 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AKT 22954
PI3K 7483
mTOR 4378
ERK 2995
Mol 2804
MAPK 2051
ERK1 1697
PTEN 1635
insulin 1587
protein kinase B 1586
Sep 1364
caspase-3 1253
p53 1250
phosphatidylinositol 3-kinase 1094
Bcl-2 973
p38 955
MEK 926
phosphoinositide 3-kinase 857
EGFR 813
epidermal growth factor receptor 812
more...
Disease
cancer 8026
tumor 6137
breast cancer 1715
tumor growth 1685
tumorigenesis 1388
hepatocellular carcinoma 928
tumor progression 804
lung cancer 781
carcinoma 764
prostate cancer 723
carcinogenesis 651
colorectal cancer 629
melanoma 605
diabetes 582
non-small cell lung cancer 516
glioma 499
leukemia 495
adenocarcinoma 492
gastric cancer 472
ovarian cancer 432
more...
Symptom
starvation 127
pain 70
seizures 57
functional recovery 50
fatigue 32
diarrhea 27
exhaustion 25
cachexia 23
collapse 19
anesthesia 18
weakness 18
splenomegaly 17
memory loss 14
respiratory distress 13
overweight 11
nausea 10
ataxia 10
hyperoxia 9
hypothermia 8
pelvic pain 8
more...
Drug
ROS 359
MAP 109
Monit 109
lysine 99
NVP 97
Dermatol 80
IL-2 71
Herceptin 69
Gefitinib 68
Sorafenib 66
Everolimus 50
Cetuximab 47
CSF 41
Imatinib 34
GEO 32
ICI 27
uPA 26
p75 26
Erlotinib 25
Cardiovasc 24
more...
Enzyme
mitogen-activated protein kinase 4957
ERK 4790
focal adhesion kinase 1584
protein kinase 1331
MEK 1116
phosphatidylinositol 3-kinase 1094
caspase-3 884
phosphoinositide 3-kinase 857
luciferase 560
AMP-activated protein kinase 559
GSK 524
PARP 455
AMPK 408
AMPK 401
protein kinase C 350
proteasome 232
PDK1 223
superoxide dismutase 202
caspase-9 199
calcineurin 164
more...
Compound
DNA 1444
Dec 1421
glucose 1336
oxygen 1220
MEK 910
tyrosine 761
MTT 719
TNF 562
Clin 522
serine 466
MDA 433
calcium 390
threonine 373
ATP 348
methionine 336
Insulin 283
nitric oxide 247
water 243
phosphate 222
cAMP 217
more...