Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P31749 (
AKT
)
22,954
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AKT
22954
PI3K
7483
mTOR
4378
ERK
2995
Mol
2804
MAPK
2051
ERK1
1697
PTEN
1635
insulin
1587
protein kinase B
1586
Sep
1364
caspase-3
1253
p53
1250
phosphatidylinositol 3-kinase
1094
Bcl-2
973
p38
955
MEK
926
phosphoinositide 3-kinase
857
EGFR
813
epidermal growth factor receptor
812
more...
Disease
cancer
8026
tumor
6137
breast cancer
1715
tumor growth
1685
tumorigenesis
1388
hepatocellular carcinoma
928
tumor progression
804
lung cancer
781
carcinoma
764
prostate cancer
723
carcinogenesis
651
colorectal cancer
629
melanoma
605
diabetes
582
non-small cell lung cancer
516
glioma
499
leukemia
495
adenocarcinoma
492
gastric cancer
472
ovarian cancer
432
more...
Symptom
starvation
127
pain
70
seizures
57
functional recovery
50
fatigue
32
diarrhea
27
exhaustion
25
cachexia
23
collapse
19
anesthesia
18
weakness
18
splenomegaly
17
memory loss
14
respiratory distress
13
overweight
11
nausea
10
ataxia
10
hyperoxia
9
hypothermia
8
pelvic pain
8
more...
Drug
ROS
359
MAP
109
Monit
109
lysine
99
NVP
97
Dermatol
80
IL-2
71
Herceptin
69
Gefitinib
68
Sorafenib
66
Everolimus
50
Cetuximab
47
CSF
41
Imatinib
34
GEO
32
ICI
27
uPA
26
p75
26
Erlotinib
25
Cardiovasc
24
more...
Enzyme
mitogen-activated protein kinase
4957
ERK
4790
focal adhesion kinase
1584
protein kinase
1331
MEK
1116
phosphatidylinositol 3-kinase
1094
caspase-3
884
phosphoinositide 3-kinase
857
luciferase
560
AMP-activated protein kinase
559
GSK
524
PARP
455
AMPK
408
AMPK
401
protein kinase C
350
proteasome
232
PDK1
223
superoxide dismutase
202
caspase-9
199
calcineurin
164
more...
Compound
DNA
1444
Dec
1421
glucose
1336
oxygen
1220
MEK
910
tyrosine
761
MTT
719
TNF
562
Clin
522
serine
466
MDA
433
calcium
390
threonine
373
ATP
348
methionine
336
Insulin
283
nitric oxide
247
water
243
phosphate
222
cAMP
217
more...