Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P31749 (AKT)
 22,954 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AKT 1.000
PI3K 0.104
mTOR 0.032
protein kinase B 0.016
ERK 0.015
PTEN 0.013
AKT1 0.008
MAPK 0.006
ERK1 0.006
phosphoinositide 3-kinase 0.005
phosphatidylinositol 3-kinase 0.005
PIK3CA 0.004
phosphatase and tensin homolog 0.003
AKT2 0.003
PKB 0.003
MEK 0.003
EGFR 0.002
RAF 0.002
GSK 0.002
STAT3 0.002
AKT3 0.002
caspase-3 0.001
JNK 0.001
p38 0.001
PI3 0.001
PDK1 0.001
IRS-1 0.001
Bcl-2 0.001
catenin 0.001
epidermal growth factor receptor 0.001
4EBP1 0.001
S6K1 0.001
P70S6K 0.001
extracellular signal-regulated kinase 0.001
AMPK 0.001
FAK 0.001
cyclin D1 0.001
p53 0.001
serine/threonine kinase 0.001
BAD 0.001
RICTOR 0.001
4E-BP1 0.001
tensin 0.001
KRAS 0.001
PARP 0.001
HER2 0.001
HER3 0.001
BRAF 0.001
MET 0.001
STAT 0.001
FOXO3 0.001
LC3 0.001
ERBB3 0.001
tyrosine kinase 0.001
VEGF 0.001
ERBB 0.001
receptor tyrosine kinase 0.001
Mol 0.001
P38 0.001
E-cadherin 0.001
PIK3 0.001
ribosomal protein S6 0.001
IGF1R 0.001
insulin 0.001
GSK3 0.001
rhabdomyosarcoma 0.000
Mcl-1 0.000
Phosphatase and tensin homolog 0.000
p27 0.000
CDK4 0.000
PIK3R1 0.000
STAT5 0.000
PIK3R2 0.000
SRC 0.000
focal adhesion kinase 0.000
p21 0.000
vascular endothelial growth factor 0.000
PIP3 0.000
MEK1 0.000
IGF-1 0.000
phosphatase 0.000
p85 0.000
ERBB2 0.000
PI3-kinase 0.000
CCK 0.000
caspase-9 0.000
Beclin-1 0.000
BAX 0.000
glycogen synthase kinase 3 beta 0.000
N-cadherin 0.000
extracellular signal-regulated kinase 1 0.000
PHLPP 0.000
VEGFR2 0.000
EGF 0.000
NRAS 0.000
IGF1 0.000
MMP-9 0.000
EMT 0.000
Cyclin D1 0.000
ROS 0.000
BCL2 0.000
p65 0.000
insulin receptor 0.000
survivin 0.000
insulin-like growth factor 0.000
MMP9 0.000
TSC2 0.000
p62 0.000
MMP2 0.000
Slug 0.000
ATG5 0.000
XIAP 0.000
annexin V 0.000
LC3B 0.000
FRAP 0.000
insulin-like growth factor 1 receptor 0.000
TNF 0.000
CREB 0.000
PHLPP2 0.000
GLUT4 0.000
c-Myc 0.000
MYC 0.000
c-Met 0.000
matrix metalloproteinase 0.000
MMP-2 0.000
JAK2 0.000
TORC2 0.000
PIK3R3 0.000
KIT 0.000
PDK 0.000
TSC1 0.000
AMP-activated protein kinase 0.000
p110 0.000
RPS6KB1 0.000
RAC 0.000
IL-6 0.000
Epidermal growth factor receptor 0.000
AXL 0.000
Phosphoinositide 3-kinase 0.000
estrogen receptor 0.000
CDK2 0.000
integrin-linked kinase 0.000
signal transducer and activator of transcription 3 0.000
PKC 0.000
pleckstrin 0.000
eNOS 0.000
CXCR4 0.000
Vimentin 0.000
c-Jun 0.000
cyclin E 0.000
serine/threonine protein kinase 0.000
c-MYC 0.000
p70 0.000
PC-3 0.000
neuregulin 0.000
p38MAPK 0.000
mitogen-activated protein 0.000
JNK1 0.000
MDM2 0.000
PIK3CD 0.000
more...
Disease
cancer 0.003
tumor 0.002
tumor growth 0.002
tumorigenesis 0.001
breast cancer 0.001
tumor progression 0.001
hepatocellular carcinoma 0.001
non-small cell lung cancer 0.001
prostate cancer 0.000
lung cancer 0.000
glioma 0.000
colorectal cancer 0.000
glioblastoma 0.000
EMT 0.000
ovarian cancer 0.000
carcinogenesis 0.000
gastric cancer 0.000
MCF 0.000
melanoma 0.000
pancreatic cancer 0.000
colon cancer 0.000
Hepatocellular carcinoma 0.000
carcinoma 0.000
tumor angiogenesis 0.000
liver cancer 0.000
B-cell lymphoma 0.000
adenocarcinoma 0.000
squamous cell carcinoma 0.000
osteosarcoma 0.000
endometrial cancer 0.000
liver cancer 0.000
DDP 0.000
leukemia 0.000
Osteosarcoma 0.000
Osteosarcoma 0.000
Glioblastoma 0.000
glioblastoma multiforme 0.000
acute myeloid leukemia 0.000
aggressiveness 0.000
T-cell acute lymphoblastic leukemia 0.000
epithelial ovarian cancer 0.000
HGF 0.000
AGS 0.000
thyroid cancer 0.000
Blocking 0.000
Proteus syndrome 0.000
bladder cancer 0.000
ABL 0.000
metastases 0.000
Multiple Lentigines 0.000
SHORT syndrome 0.000
cervical cancer 0.000
tumor initiation 0.000
Melanoma 0.000
tuberous sclerosis 0.000
renal cell carcinoma 0.000
type 2 diabetes 0.000
multiple myeloma 0.000
Esophageal squamous cell carcinoma 0.000
diabetes 0.000
anaplastic thyroid cancer 0.000
obesity 0.000
retinoblastoma 0.000
lymphoma 0.000
hyperglycemia 0.000
neuroblastoma 0.000
HCC 0.000
brain tumor 0.000
metastatic melanoma 0.000
AS1 0.000
mantle cell lymphoma 0.000
ATM 0.000
MTS 0.000
ischemia 0.000
chronic myeloid leukemia 0.000
Cowden syndrome 0.000
chronic lymphocytic leukemia 0.000
metastatic follicular thyroid cancer 0.000
Thyroid cancer 0.000
Neuroblastoma 0.000
Neuroblastoma 0.000
leukemogenesis 0.000
papillary thyroid cancer 0.000
skin cancer 0.000
esophageal cancer 0.000
chronic lymphocytic leukemia 0.000
lung carcinoma 0.000
liver fibrosis 0.000
thymoma 0.000
Nasopharyngeal carcinoma 0.000
brain cancer 0.000
Leukemia 0.000
sarcoma 0.000
esophageal cancer 0.000
Keratocystic Odontogenic Tumor 0.000
ADMD 0.000
Alcoholic liver damage 0.000
Silence 0.000
clear cell carcinoma 0.000
gallbladder cancer 0.000
metastatic breast cancer 0.000
Alzheimer's disease 0.000
primary tumor 0.000
Hippel 0.000
cerebral ischemia 0.000
fatty liver 0.000
pre-T LBL 0.000
rhabdomyosarcoma 0.000
laryngeal squamous cell carcinoma 0.000
NOD 0.000
Diffuse large B-cell lymphoma 0.000
SCID 0.000
medulloblastoma 0.000
glucose intolerance 0.000
Cholangiocarcinoma 0.000
Cholangiocarcinoma 0.000
T Cell Leukemia 0.000
Medulloblastoma 0.000
diabetic cardiomyopathy 0.000
renal cancer 0.000
Costello syndrome 0.000
solid tumor 0.000
FAS 0.000
hyperinsulinemia 0.000
acute lymphoblastic leukemia 0.000
stromal tumors 0.000
Hepatocarcinogenesis 0.000
Ruvalcaba syndrome 0.000
PIN 0.000
phakoma 0.000
mammary tumor 0.000
oral cancer 0.000
Diabetic gastroparesis 0.000
FTC 0.000
hematologic malignancies 0.000
GSH 0.000
Endocrine pancreas 0.000
Endocrine pancreas 0.000
gastrointestinal stromal tumor 0.000
Parkinson's disease 0.000
DLBCL 0.000
mesothelioma 0.000
Neonatal necrotizing enterocolitis 0.000
CLL transformation 0.000
Gallbladder carcinoma 0.000
PARK7 0.000
pediatric solid tumor 0.000
diabetic nephropathy 0.000
osteoporosis 0.000
squamous cell carcinoma of the skin 0.000
recurrent endometrial cancer 0.000
Malignant glioma 0.000
High altitude cerebral edema 0.000
FHL2 0.000
uveal melanoma 0.000
Nonalcoholic fatty liver 0.000
atherosclerosis 0.000
Rhabdomyosarcoma 0.000
refractory CML 0.000
adult brain tumor 0.000
more...
Symptom
starvation 0.000
functional recovery 0.000
Mucosal hyperplasia 0.000
Scratch 0.000
difficulty with urination 0.000
finger pain 0.000
cachexia 0.000
musculoskeletal disability 0.000
memory loss 0.000
exhaustion 0.000
Motor dysfunction 0.000
skin damage 0.000
seizures 0.000
splenomegaly 0.000
stomach pain 0.000
fatigue 0.000
impaired motor coordination 0.000
pelvic pain 0.000
pain 0.000
hyperoxia 0.000
urinary frequency 0.000
collapse 0.000
diarrhea 0.000
respiratory distress 0.000
weakness 0.000
hepatomegaly 0.000
cancer pain 0.000
decreased appetite 0.000
ataxia 0.000
swollen joints 0.000
ataxic gait 0.000
halitosis 0.000
thinning 0.000
overweight 0.000
acute stress 0.000
nausea 0.000
incoordination 0.000
hypothermia 0.000
Depressive symptoms 0.000
hypotonia 0.000
skin irritation 0.000
acute pain 0.000
Stiffness 0.000
bradykinesia 0.000
microbial colonization 0.000
hot flashes 0.000
low back pain 0.000
anorexia 0.000
dry eye 0.000
wheezing 0.000
anesthesia 0.000
knee pain 0.000
chronic constipation 0.000
bone pain 0.000
Neuropathic pain 0.000
despair 0.000
menopausal symptoms 0.000
enuresis 0.000
arthralgia 0.000
chronic cough 0.000
leg pain 0.000
acidity 0.000
constipation 0.000
masculinization 0.000
vomiting 0.000
cough 0.000
asthenia 0.000
paraparesis 0.000
sore throat 0.000
myalgia 0.000
agitation 0.000
dyspnea 0.000
analgesia 0.000
ophthalmoplegia 0.000
epigastric pain 0.000
hypercapnia 0.000
cerebellar ataxia 0.000
neck pain 0.000
chills 0.000
nausea and vomiting 0.000
hepatosplenomegaly 0.000
ENT 0.000
back pain 0.000
hemoptysis 0.000
spasticity 0.000
tinnitus 0.000
chest pain 0.000
abdominal pain 0.000
tremor 0.000
distraction 0.000
angina 0.000
discomfort 0.000
discomfort 0.000
Ill 0.000
erythema 0.000
headache 0.000
Drug
NVP 0.000
ROS 0.000
Gefitinib 0.000
Everolimus 0.000
Sorafenib 0.000
Cetuximab 0.000
Herceptin 0.000
Efipladib 0.000
Caprylic Acid 0.000
Erlotinib 0.000
Canertinib dihydrochloride 0.000
MAP 0.000
Dasatinib 0.000
Epigallocatechin 0.000
3-Methyladenine 0.000
GEO 0.000
RAL 0.000
Tarceva 0.000
Imatinib 0.000
Epimedium herb 0.000
Emodin 0.000
Bupleurum root 0.000
Purvalanol 0.000
Vandetanib 0.000
uPA 0.000
Arsenic trioxide 0.000
Monit 0.000
Emodin 0.000
Zedoary 0.000
Romidepsin 0.000
Tykerb 0.000
Bosutinib 0.000
Insulin glulisine 0.000
Casodex 0.000
Gleevec 0.000
Romet 0.000
Fenobam 0.000
Bortezomib 0.000
Medalist 0.000
Atractylodes rhizome 0.000
p75 0.000
Pertuzumab 0.000
Glycyrrhiza 0.000
Benzofuran 0.000
IL-2 0.000
Rosiglitazone 0.000
Simvastatin 0.000
Ferric ammonium citrate 0.000
Tobi 0.000
Pirarubicin 0.000
lysine 0.000
Tanespimycin 0.000
Bindarit 0.000
Myricetin 0.000
Pemetrexed 0.000
Sodium dichloroacetate 0.000
Alarin 0.000
Sodium Nitroprusside 0.000
Nexavar 0.000
Liraglutide 0.000
ICI 0.000
Avobenzone 0.000
ADR 0.000
Berberine chloride 0.000
Atazanavir sulfate 0.000
Vorinostat 0.000
Sesamol 0.000
Fidarestat 0.000
Fidarestat 0.000
Safflower 0.000
ETS 0.000
Polaprezinc 0.000
Nelarabine 0.000
CCL 0.000
Vinpocetine 0.000
Lipitor 0.000
TTC 0.000
NLF 0.000
RFP 0.000
Glucagon 0.000
Docetaxel 0.000
Azilect 0.000
Swainsonine 0.000
DM1 0.000
CAM 0.000
Taxol 0.000
Amlexanox 0.000
Insulin aspart 0.000
PTC 0.000
Darifenacin 0.000
Bevacizumab 0.000
TAK 0.000
Avandia 0.000
Lipitor 0.000
Lipitor 0.000
R1881 0.000
Parkin 0.000
Parkin 0.000
1-Deoxynojirimycin 0.000
Red ginseng 0.000
NOV 0.000
KGF 0.000
Fluphenazine 0.000
Artesunate 0.000
Tianma 0.000
Humalog 0.000
Epidoxorubicin 0.000
Roflumilast 0.000
Roflumilast 0.000
Troglitazone 0.000
Levitra 0.000
Retinoic Acid 0.000
Donepezil 0.000
Clofarabine 0.000
Heme 0.000
TEL 0.000
Ebastine 0.000
Sunitinib malate 0.000
Amlodipine besylate 0.000
Aliskiren 0.000
Abamectin 0.000
Dextran sulfate sodium 0.000
Radicicol 0.000
Gelatin 0.000
Pramlintide 0.000
CSF 0.000
Tipifarnib 0.000
Revlimid 0.000
Adriamycin 0.000
ABC 0.000
Panitumumab 0.000
Levitra 0.000
Oxaliplatin 0.000
Atovaquone 0.000
Bexarotene 0.000
CoCl2 0.000
CoCl2 0.000
Vardenafil 0.000
PFT 0.000
CPZ 0.000
Ciglitazone 0.000
Alimta 0.000
Propentofylline 0.000
Lovastatin 0.000
Activin 0.000
EE2 0.000
Fulvestrant 0.000
Estrogens 0.000
Angiotensin II 0.000
IL-11 0.000
MINO 0.000
Etoposide 0.000
Retinoic acid 0.000
Valproic Acid 0.000
Verteporfin 0.000
Ferumoxytol 0.000
Sodium thiosulfate 0.000
Atovaquone 0.000
DEX 0.000
Quinine, 0.000
more...
Enzyme
mitogen-activated protein kinase 0.011
ERK 0.010
phosphoinositide 3-kinase 0.005
phosphatidylinositol 3-kinase 0.005
MEK 0.003
focal adhesion kinase 0.002
GSK 0.002
AMPK 0.001
AMP-activated protein kinase 0.001
PDK1 0.001
caspase-3 0.001
protein kinase 0.001
PARP 0.001
AMPK 0.001
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
luciferase 0.000
caspase-9 0.000
inositol 3-kinase 0.000
TOR 0.000
IKK 0.000
protein kinase C 0.000
HK2 0.000
proteasome 0.000
calcineurin 0.000
caspase-8 0.000
protein phosphatase 2A 0.000
cdc2 0.000
MAP 0.000
superoxide dismutase 0.000
NADPH oxidase 0.000
MMP 0.000
NADPH oxidase 0.000
STK11 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 0.000
caspase-7 0.000
caspase-7 0.000
inositol polyphosphate 4-phosphatase 0.000
AMP-activated kinase 0.000
MPP 0.000
matrix metalloproteinase 2 0.000
STK13 0.000
sphingosine kinase 0.000
MEKK1 0.000
catalase 0.000
lactate dehydrogenase 0.000
matrix metalloproteinase 9 0.000
P-glycoprotein 0.000
urokinase-type plasminogen activator 0.000
glucose-6-phosphatase 0.000
cathepsin K 0.000
acetyl-CoA carboxylase 0.000
heme oxygenase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
GRK2 0.000
phosphatidylinositol 3-phosphate 5-kinase 0.000
prenylated protein methyltransferase 0.000
ALDH 0.000
polo-like kinase 1 0.000
matrix metalloproteinase 14 0.000
MMP-3 0.000
CaMKII 0.000
hormone-sensitive lipase 0.000
DCF 0.000
BCKDH 0.000
phospholipase C 0.000
collagenase 0.000
PKG 0.000
tyrosinase 0.000
MGAT 0.000
proteinase-3 0.000
ATPase 0.000
PLP phosphatase 0.000
D-dopachrome tautomerase 0.000
NO synthase 0.000
alkaline phosphatase 0.000
NQO1 0.000
alanine aminotransferase 0.000
aspartate aminotransferase 0.000
glutathione S-transferase 0.000
APC 0.000
glutathione peroxidase 0.000
matrix metalloproteinase 10 0.000
GRK5 0.000
NOS 0.000
isochorismatase 0.000
fucokinase 0.000
chondroitin 6-sulfotransferase 0.000
STK4 0.000
granzyme B 0.000
GalT 0.000
GK2 0.000
arginase 0.000
histone demethylase 0.000
cholesterol 25-hydroxylase 0.000
CMP-Neu5Ac hydroxylase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
ceramide kinase 0.000
lysyl oxidase 0.000
TACE 0.000
PTPase 0.000
demethylase 0.000
thioredoxin reductase 0.000
topoisomerase 0.000
triphosphatase 0.000
site-1 protease 0.000
farnesyltransferase 0.000
phosphofructokinase 1 0.000
acylglycerol kinase 0.000
PHD 0.000
AST 0.000
DNA methyltransferase 0.000
lysophospholipase D 0.000
CPT 0.000
site-1 protease 0.000
topoisomerase 0.000
glucokinase 0.000
SPC 0.000
TdT 0.000
reverse transcriptase 0.000
isopeptidase 0.000
phosphodiesterase 0.000
pantothenate synthetase 0.000
cathepsin B 0.000
hepsin 0.000
malonyl-CoA decarboxylase 0.000
hepsin 0.000
STK 0.000
complex I 0.000
Protein 2 0.000
farnesyltransferase 0.000
peroxidase 0.000
caspase-6 0.000
GAS 0.000
histidine kinase 0.000
caspase-6 0.000
pyruvate dehydrogenase 0.000
pyruvate dehydrogenase 0.000
CEP 0.000
6-phosphofructo-2-kinase 0.000
GD3 synthase 0.000
inositol phosphatase 0.000
prostate-specific antigen 0.000
caspase-2 0.000
STK3 0.000
CPT 0.000
gamma-glutamylcysteine synthetase 0.000
aldehyde dehydrogenase 0.000
aldehyde dehydrogenase 0.000
caspase-2 0.000
aldehyde dehydrogenase 0.000
pyruvate dehydrogenase phosphatase 0.000
aldehyde dehydrogenase 0.000
pyruvate kinase 0.000
CYP8B1 0.000
nicotinamide phosphoribosyltransferase 0.000
STK2 0.000
pregnancy-associated plasma protein-A 0.000
CPT 0.000
more...
Compound
MEK 0.003
MTT 0.001
MDA 0.000
Phosphatidylinositol 0.000
tyrosine 0.000
glucose 0.000
Rapamycin 0.000
TNF 0.000
oxygen 0.000
Vimentin 0.000
serine 0.000
threonine 0.000
Insulin 0.000
Wortmannin 0.000
DNA 0.000
DDP 0.000
TNM 0.000
methionine 0.000
TSC 0.000
BCR 0.000
Metformin 0.000
Metformin 0.000
C20H21NO5 0.000
C20H21NO5 0.000
Plantamajoside 0.000
C20H21NO5 0.000
C20H21NO5 0.000
C20H21NO5 0.000
C20H21NO5 0.000
Chelerythrine hydrochloride 0.000
ABL 0.000
dUTP 0.000
Bruceine D 0.000
Tamarixetin 0.000
Shikonin 0.000
Resveratrol 0.000
MTS 0.000
MAP 0.000
LY 294002 0.000
C14H16N2O4S 0.000
C21H20N2O2 0.000
C19H18O7 0.000
4-Bromodiphenyl ether 0.000
C16H12O4 0.000
Deltonin 0.000
Deguelin 0.000
Gentisyl alcohol 0.000
4-Bromodiphenyl ether 0.000
C16H20O5 0.000
Jervine 0.000
Farrerol 0.000
Dec 0.000
ATP 0.000
Garcinol 0.000
Temsirolimus 0.000
Sinulariolide 0.000
cAMP 0.000
Matrine 0.000
Matrine 0.000
Matrine 0.000
Papaverinol 0.000
Columbamine 0.000
Spectinabilin 0.000
Selenocystine 0.000
Eurycomalactone 0.000
Galangin 0.000
N-acetylcysteine 0.000
Bufalin 0.000
Curcumin 0.000
Cyclovirobuxine D 0.000
3-Methyladenine 0.000
Luteolin 0.000
Ailanthone 0.000
Apigetrin 0.000
Dihydrorotenone 0.000
Heterophyllin 0.000
furostan-3,26-diol 0.000
3-fluorobenzamide 0.000
Deuterohemin 0.000
2-acetyl-1,3-cyclopentanedione 0.000
Auriculasin 0.000
cyclohexyl salicylate 0.000
Deuterohemin 0.000
C16H14O3 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
ADP-ribose 0.000
Aplysin 0.000
Tanshinone 0.000
nitric oxide 0.000
Gambogic acid 0.000
Baicalein 0.000
Isoliquiritigenin 0.000
Delphinidin 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
Mahanimbine 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
Astragaloside III 0.000
C19H18O3 0.000
C19H18O3 0.000
C19H18O3 0.000
2,2',4,4',5,5'-Hexachlorobiphenyl 0.000
Fisetin 0.000
Pachymic acid 0.000
celastrol 0.000
Naringin 0.000
6-Gingerol 0.000
Ovatodiolide 0.000
Glycogen synthase 0.000
bromide 0.000
Geniposide 0.000
Triptolide 0.000
Celastrol 0.000
Carlina oxide 0.000
[6]-Gingerol 0.000
C19H18O3 0.000
5-Methoxytryptophan 0.000
Rutamarin 0.000
Maclurin 0.000
C19H18O3 0.000
Vasicinone 0.000
Oridonin 0.000
Formononetin 0.000
Ailanthone 0.000
Epigallocatechin 0.000
Magnolol 0.000
Fangchinoline 0.000
Wogonin 0.000
THP 0.000
calcium 0.000
MPP 0.000
Polydatin 0.000
Serine 0.000
NOXA 0.000
THP 0.000
Glycitin 0.000
C19H18O3 0.000
Hydrangenol 0.000
Virosecurinine 0.000
Guaiol 0.000
Eupatolide 0.000
Nobiletin 0.000
MPP 0.000
Alantolactone 0.000
Raddeanin A 0.000
Berberine 0.000
STZ 0.000
more...