Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P30536 (
PBS
)
9,886
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A novel mitochondria-targeting fluorescent probe compound S-N
3
for hydrogen sulfide (H
2
S) in living cells has been designed and synthesized in this study. This article contained the chemosynthesis and some studies on bioactivity of the target compound in living cells.
Compound S
-N
3
is easy to synthesize and can remain stable under the effect of pH, system and photostability. In addition, it shows low cytotoxicity in cell imaging. And it can react with H
2
S highly selective in
PBS
or FBS solution, which would cause the obvious increase in fluorescence intensity. Therefore, the low-cost detection method for H
2
S is allowed for monitoring the quantity of H
2
S existed in the mitochondria.
...
PMID:A novel mitochondria-targeting fluorescent probe for hydrogen sulfide in living cells. 2810 34
