Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P30044 (antioxidant enzyme)
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Human Gene/Protein
antioxidant enzyme 12.0
heat shock 70 kDa protein 9B 11.0
26S protease regulatory subunit 6B 10.4
Heparan sulfate proteoglycan 2 10.0
selenoprotein I 9.8
WD repeat domain, phosphoinositide interacting 1 9.6
Manganese superoxide dismutase 9.6
Extracellular superoxide dismutase 9.5
selenoprotein O 9.4
aldehyde dehydrogenase I 9.4
Cardiotrophin 1 9.4
CPF2 9.4
SK 2 9.1
GPX6 9.1
transcription factor 15 9.1
HAO2 9.0
transcription factor NRF 9.0
Superoxide dismutase 1 8.9
SRXN1 8.8
Glutathione peroxidase 8.8
SEPHS2 8.8
GPX1 protein 8.8
SELT 8.8
Peroxiredoxin 6 8.7
peroxiredoxin 4 8.7
claudin 15 8.6
AP-2B 8.6
ccp1 8.6
Peroxiredoxin 5 8.6
endothelial adhesion molecule 1 8.6
extracellular superoxide dismutase 8.6
manganese superoxide dismutase 8.5
thioredoxin peroxidase 8.5
glutathione peroxidase 6 8.5
glutathione peroxidase 8.5
SOD3 8.5
Thioredoxin reductase 1 8.4
SOD2 protein 8.4
Raftlin 8.4
GPX4 protein 8.4
ESCS 8.4
MnSOD 8.4
glutathione peroxidase 1 8.3
SESN3 8.3
MT1R 8.3
delta-9-desaturase 8.3
CLCA3 8.3
PRX2 8.3
TIP120B 8.3
claudin-12 8.2
peroxiredoxin 6 8.1
RPL31 8.1
integrin-like protein 8.1
AMN1 8.1
gpx5 8.1
RNF6 8.1
glutathione reductase 8.1
peroxiredoxin 5 8.0
tetratricopeptide repeat-containing protein 8.0
Prx 8.0
G1L 8.0
NEBL 8.0
Selenoprotein M 8.0
mitochondrial topoisomerase I 8.0
CUEDC2 8.0
Catalase 7.9
phospholipid hydroperoxide glutathione peroxidase 7.9
GPX1 7.9
erythrocyte glutathione peroxidase 7.9
catalase 7.9
superoxide dismutase 7.9
SOD2 7.9
G6PD protein 7.9
ECH1 7.9
PIP5K2A 7.9
Superoxide dismutase 7.9
claudin-15 7.8
Paraoxonase 1 7.8
EC-SOD 7.8
SNX14 7.8
more...
Disease
Barrett's Adenocarcinoma 10.0
Barrett's Adenocarcinoma 10.0
ESCS 8.5
SPG13 8.4
Neonatal anoxia 8.1
ALAD deficiency 8.0
Hereditary canine spinal muscular atrophy 8.0
EPM2B 7.8
Recurrent apnea 7.8
Age-associated memory impairment 7.8
Anterior segment dysgenesis 7.8
idiopathic proctocolitis 7.6
sexual dysfunction and infertility 7.4
testicular dysfunction 6.9
GSH 6.8
Muscle degeneration 6.7
WTS 6.6
Cholesterol gallstones 6.6
Takahara 6.5
Neonatal encephalopathy 6.4
acute alcoholism 6.4
Oxygen toxicity 6.4
mouse leukemia P388 6.4
Spring viremia of carp 6.2
sCJD 6.2
hypermethioninemia 6.1
white muscle disease 5.9
Systemic inflammatory response syndrome (SIRS) 5.9
diabetic cataract 5.8
ependymal tumors 5.8
Transient ischemia 5.7
MEV 5.7
Crabs 5.7
KAR 5.6
scrofula 5.6
GS3 5.5
Transient cerebral ischemia 5.5
Testicular torsion 5.4
disorders of iron metabolism 5.3
Postinfarction 5.1
Mesenteric ischemia 5.1
Chronic progressive external ophthalmoplegia 5.1
breast cancer stage 5.1
aspermia 5.0
GA I 5.0
Hepatotoxicity 5.0
variegate porphyria 4.9
favism 4.9
Diaphragm 4.9
Pineal 4.9
Acute gastroenteritis 4.9
Chronic heart failure 4.9
reproductive disorder 4.9
Hepatic necrosis 4.8
Vulvovaginal candidiasis 4.8
Diabetic complications 4.8
diabetic angiopathy 4.8
riboflavin deficiency 4.7
RP3 4.7
Ileum 4.7
Periventricular leukomalacia 4.7
JIP 4.7
Retinal ischemia 4.7
Cancer cachexia 4.7
Social Anxiety 4.6
Intestinal ischemia 4.6
Copper deficiency 4.6
hyperargininemia 4.6
EDS1 4.5
FGG 4.5
Keshan disease 4.5
UIP 4.5
LPI 4.4
SD1 4.4
LCS 4.4
HSP 4.4
tardive dyskinesia 4.3
acute alcohol intoxication 4.3
intestinal cancer 4.3
kidney hypertrophy 4.3
more...
Symptom
Chronic pelvic pain syndrome 7.1
hyperoxia 6.3
Stinging 6.2
Subjective tinnitus 5.8
loss of equilibrium 4.8
skin damage 4.6
Anoxia 4.4
body pain 3.9
chills 3.8
Involuntary Movement 3.3
Catch 2.9
acute stress 2.8
exhaustion 2.5
despair 2.3
neurological disability 2.1
emaciation 1.9
catatonia 1.8
functional recovery 1.8
hypoproteinemia 1.8
starvation 1.8
thinning 1.5
acidity 1.4
polyuria 1.4
physical appearance 1.4
incoordination 1.2
memory loss 1.1
sneezing 1.1
hypercapnia 1.0
twitching 1.0
constipation 1.0
fatigue 0.9
blurred vision 0.9
chorea 0.9
heartburn 0.9
respiratory distress 0.9
tinnitus 0.8
polydipsia 0.8
bradykinesia 0.8
overweight 0.7
masculinization 0.6
numbness 0.6
collapse 0.6
knee pain 0.5
hepatomegaly 0.5
HSA 0.4
tremor 0.4
ataxia 0.3
hypothermia 0.2
cerebellar ataxia 0.1
dysarthria 0.1
weakness 0.1
seizures 0.1
erythema -0.1
stigma -0.2
anorexia -0.2
wheezing -0.3
dizziness -0.3
ENT -0.4
anesthesia -0.5
cachexia -0.5
lethargy -0.5
diarrhea -0.5
flushing -0.7
myalgia -0.7
arthralgia -0.9
spasm -0.9
discomfort -0.9
cough -1.0
discomfort -1.0
nausea and vomiting -1.3
angina -1.4
agitation -1.6
back pain -1.6
pain -2.0
chest pain -2.1
headache -2.2
dyspnea -2.8
Drug
C14H12N6O 12.0
Camellia oil 9.1
Glyceryl behenate 9.1
Isoxsuprine hydrochloride 9.1
Diammonium glycyrrhizinate 9.1
Idoxifene 8.8
1,4-Dithiothreitol 8.5
Oyster shell 8.5
Gluthathione 8.3
Cianidanol 8.0
Crotonaldehyde 7.8
Plasmanate 7.6
Kytril 7.4
Ferrlecit 7.4
Kytril 7.3
Tricyclazole 7.3
Motexafin gadolinium 7.3
Manganese chloride 7.0
Metoclopramide hydrochloride 6.9
Azilect 6.6
Gly-Tyr-Gly 6.6
Stannous chloride 6.5
Sodium metabisulfite 6.5
Omacor 6.5
Venofer 6.4
Eprinomectin 6.3
Solon 6.3
Lantus 6.3
Aluminum chloride 6.2
Sesamol 6.1
Red ginseng 6.1
Nipradilol 6.0
ROS 6.0
Primperan 6.0
Fotemustine 5.9
Glutathione 5.8
Zebularine 5.8
Jujube 5.8
Rutin 5.8
Pyridoxamine 5.8
Heme 5.7
Pyridostigmine bromide 5.7
Ciprofibrate 5.6
Auranofin 5.6
Pyridostigmine bromide 5.5
Epigallocatechin 5.5
Furan 5.4
Zinc sulfate 5.4
Zinc sulfate 5.4
Sodium thiosulfate 5.4
Malonaldehyde 5.3
Levosimendan 5.3
ascorbate 5.3
Aricept 5.2
Trilostane 5.2
Dantrolene sodium 5.2
vitamin E 5.1
Ulinastatin 5.1
Vitamin E 5.1
Ginger 5.1
Safflower 5.0
Compound 15 5.0
ATV 5.0
Kelp 4.9
Areca 4.9
Vanilla 4.8
Febuxostat 4.8
Soybean oil 4.7
Rasagiline 4.7
Emodin 4.6
Lead acetate 4.6
Monosodium glutamate 4.6
Podophyllum 4.6
3-Methyladenine 4.6
EML 4.5
Inderal 4.5
CrCl3 4.4
Tannic acid 4.4
Emodin 4.4
FAD 4.3
more...
Enzyme
EC 1.5.1.18 12.0
ascorbate peroxidase 8.6
2-alkenal reductase 8.5
glutathione peroxidase 8.4
phospholipid hydroperoxide glutathione peroxidase 8.4
dehydroascorbate reductase 8.3
2-alkenal reductase 8.3
glutathione reductase 8.1
UDP-sulfoquinovose synthase 8.0
sulfiredoxin 8.0
superoxide dismutase 7.9
catalase 7.8
peroxiredoxin 7.6
thioredoxin reductase 7.6
desulfhydrase 7.3
4-nitrophenol hydroxylase 7.2
AAO3 7.2
SOR 7.2
nitric oxide dioxygenase 6.8
methionine decarboxylase 6.8
paraoxonase 6.8
carnosine synthetase 6.7
N-acetylglucosamine 2-epimerase 6.7
NADPH:quinone oxidoreductase 6.6
N-acetylmannosamine kinase 6.6
NADH peroxidase 6.5
inositol polyphosphate kinase 6.5
AtHMA4 6.4
paraoxonase 6.4
putrescine N-methyltransferase 6.4
disulfide reductase 6.4
glycine reductase 6.3
gamma-glutamylcysteine synthetase 6.2
MsrA 6.2
gamma-glutamyl kinase 6.2
polyamine oxidase 6.1
methionine sulfoxide reductase 6.1
glutathione S-transferase 5.9
SBPase 5.9
heme oxygenase 5.9
proline oxidase 5.9
flavanone 3-hydroxylase 5.8
amorpha-4,11-diene synthase 5.8
ECH 5.7
NQO1 5.7
glucose-6-phosphate dehydrogenase 5.7
mercuric reductase 5.6
ABA 8'-hydroxylase 5.6
protein L-isoaspartyl methyltransferase 5.6
KAR 5.6
galactinol synthase 5.5
isopentenyltransferase 5.4
D-aspartate oxidase 5.4
phosphoglycolate phosphatase 5.4
phosphomevalonate kinase 5.4
NQO2 5.4
peroxidase 5.3
isoprene synthase 5.2
cytokinin oxidase/dehydrogenase 5.2
aconitase 5.2
AST 5.1
xanthine oxidase 5.1
NADPH oxidase 5.1
oxalate oxidase 5.1
NADPH oxidase 5.1
aryl-alcohol oxidase 5.1
versatile peroxidase 5.0
superoxide reductase 5.0
aspartate aminotransferase 5.0
allantoinase 5.0
cysteine synthase 5.0
alliinase 5.0
delta-aminolevulinic acid dehydratase 4.9
biliverdin reductase 4.8
isochorismate synthase 4.8
chalcone isomerase 4.8
macrophage elastase 4.8
alanine aminotransferase 4.8
ceruloplasmin 4.8
flavin reductase 4.7
more...
Compound
C14H12N6O 12.0
Ardisin 12.0
2,2,5-trimethyl-1,3-oxazolidine 11.0
C12H9N5O2 11.0
2-(4-chlorophenyl)benzo-1,4-quinone 10.4
Deuterohemin 10.0
Deuterohemin 10.0
Eburicoic acid 10.0
Huperzine B 9.6
Ethyl cinnamate 9.0
2-Mercaptobenzimidazole 8.9
Saponarin 8.8
Fraxin 8.8
2H-chromene-3-carboxylic acid 8.6
Plantamajoside 8.6
Karanjin 8.6
Metazachlor 8.6
4-hydroxyisophthalic acid 8.5
Isopulegol 8.4
butyl 4-hydroxybenzoate 8.3
2,4-Di-tert-butylphenol 8.3
aminomethanesulfonic acid 8.3
aminomethanesulfonic acid 8.3
Isopulegol 8.3
2,4-Di-tert-butylphenol 8.1
Eriocitrin 8.1
aminomethanesulfonic acid 8.0
DHICA 8.0
Securinine 8.0
Aminoantipyrine 8.0
Pinitol 8.0
Isoorientin 8.0
Gelsemine 8.0
butyl 4-hydroxybenzoate 8.0
aminomethanesulfonic acid 8.0
Bikaverin 7.9
Potassium dichromate 7.8
Isobavachalcone 7.8
Sclareol 7.7
1-methyl-1H-pyrrole 7.6
Selenocystine 7.5
CAT 7.5
CAT 7.5
Diosmin 7.5
CAT 7.4
L-Gulonolactone 7.4
Chlorophyllide 7.4
Echinacoside 7.3
Sulfuretin 7.3
Zingerone 7.3
Dichlofluanid 7.3
Pinitol 7.2
3,4-dimethoxybenzoic acid 7.2
Queuine 7.2
Jatrorrhizine 7.2
Bendiocarb 7.1
Trigonelline 7.1
Propiconazole 7.1
Nitro blue tetrazolium 7.1
Interferon beta-1b 7.1
Thiobarbituric acid 7.0
8-Hydroxyguanine 7.0
Quinalphos 7.0
Syringin 7.0
Tetryl 7.0
Malondialdehyde 7.0
Vitexin 7.0
Nickel sulfate 7.0
2,6-DMA 7.0
Alliin 7.0
Cyhalothrin 7.0
Thioredoxin 6.9
Sertindole 6.9
EH2 6.9
Fucosterol 6.9
Lead nitrate 6.9
Raspberry ketone 6.9
Dimethylglycine 6.8
GSSG 6.8
Fucosterol 6.8
more...