Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P30044 (antioxidant enzyme)
 8,037 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
antioxidant enzyme 8037
superoxide dismutase 2926
catalase 2855
glutathione peroxidase 1904
GSH 1048
SOD 787
glutathione reductase 655
Mol 549
Sep 543
peroxidase 481
CAT 413
ROS 312
caspase-3 249
insulin 239
MnSOD 230
Catalase 221
glutathione S-transferase 221
manganese superoxide dismutase 210
TNF 209
Nrf2 196
heme oxygenase-1 186
thioredoxin 176
lactate dehydrogenase 176
Superoxide dismutase 174
Bcl-2 157
erythroid 154
tumor necrosis factor 154
NADPH 143
cytokine 136
SOD1 135
aspartate aminotransferase 125
GST 117
thioredoxin reductase 117
p53 112
Glutathione peroxidase 108
inducible nitric oxide synthase 107
IL-6 105
SOD2 100
reductase 98
ATP 97
myeloperoxidase 96
alanine aminotransferase 89
glucose-6-phosphate dehydrogenase 86
p38 86
glutathione peroxidase 1 84
collagen 83
lipopolysaccharide 83
alkaline phosphatase 80
HO-1 79
nitric oxide synthase 78
albumin 76
ATPase 75
MAPK 74
acetylcholinesterase 73
xanthine oxidase 73
Prx 70
APE1 68
carp 62
Manganese superoxide dismutase 59
NQO1 58
HDL 58
interleukin-6 57
HSP70 57
endoplasmic reticulum 56
hemoglobin 55
AST 53
gut 51
JNK 50
heat shock protein 49
caspase-9 49
cytochrome c 49
LDH 49
Cu/Zn superoxide dismutase 49
superoxide dismutase 1 47
NAD 47
creatine kinase 43
cyclooxygenase-2 43
metallothionein 43
paraoxonase 42
PI3K 42
erythrocyte glutathione peroxidase 41
glutathione transferase 40
oxidoreductase 39
IL-10 39
LPS 38
GSR 37
IL-8 37
COX-2 37
selenoprotein 36
ERK 36
spermatozoa 35
proteasome 35
extracellular superoxide dismutase 35
AKT 35
Pseudomonas 34
LPO 33
cytochrome P450 32
tumor necrosis factor alpha 32
lysozyme 32
amylase 31
angiotensin II 31
p65 30
xenobiotic 30
peroxisome proliferator-activated receptor 30
TNF-alpha 30
c-Jun 30
ceruloplasmin 30
CO2 29
Thioredoxin 29
DT-diaphorase 29
ERK1 29
mitogen-activated protein 29
epididymal 28
quinone oxidoreductase 28
FAD 28
polypeptide 27
PEG 27
citrate synthase 27
GPX1 27
NADH 27
brain-derived neurotrophic factor 27
glutathione peroxidase 4 26
mTOR 26
NADP 26
ferritin 26
IL-1 25
ALP 25
thioredoxin peroxidase 25
SOD3 25
NF-E2-related factor 2 25
extracellular signal-regulated kinase 24
proliferating cell nuclear antigen 24
glutamine synthetase 24
peroxiredoxin 6 24
Extracellular superoxide dismutase 23
C-reactive protein 23
matrix metalloproteinase 23
cytochrome 23
PGC 23
TLR4 22
IFN 22
microsomal 22
phospholipid hydroperoxide glutathione peroxidase 21
lipase 21
Bot 21
adiponectin 21
thyroid hormone 21
ubiquitin 20
ANOVA 20
Gen 20
lipoxygenase 20
bcl-2 20
NF-E2 20
cytochrome c oxidase 20
leptin 20
endothelial nitric oxide synthase 20
Kelch-like ECH-associated protein 1 20
AMP-activated protein kinase 19
phosphatidylinositol 3-kinase 19
Trx 19
more...
Disease
GSH 1048
cancer 436
diabetes 328
tumor 221
ischemia 206
Alzheimer's disease 124
atherosclerosis 120
cold 113
carcinogenesis 105
hypertension 101
Parkinson's disease 94
obesity 90
hyperglycemia 83
type 2 diabetes 73
breast cancer 67
amyotrophic lateral sclerosis 66
cardiovascular disease 66
hepatocellular carcinoma 59
stroke 53
depression 50
cerebral ischemia 48
hyperlipidemia 47
heart failure 44
MCF 41
hypercholesterolemia 39
NAME 35
myocardial infarction 33
tumor growth 33
myocardial ischemia 33
metabolic syndrome 33
tumorigenesis 32
prostate cancer 32
neuroblastoma 32
adenocarcinoma 32
dehydration 31
tumor progression 30
fatty liver 29
diabetic nephropathy 28
dyslipidemia 27
renal disease 27
carcinoma 27
cardiomyopathy 26
worms 26
epididymis 25
Pineal 25
sepsis 24
colon cancer 24
sepsis 24
asthma 23
pheochromocytoma 23
preeclampsia 22
proteinuria 22
chronic obstructive pulmonary disease 22
schizophrenia 22
lung cancer 22
colitis 21
infectious diseases 21
plaque 21
memory impairment 21
liver disease 20
male infertility 20
leukemia 20
pulmonary fibrosis 20
dementia 20
malnutrition 20
bacterial infection 19
type 1 diabetes 19
colorectal cancer 19
cataract 19
epilepsy 19
lymphoma 18
B-cell lymphoma 18
cognitive impairment 18
melanoma 18
coronary artery disease 17
SDS 17
uterus 16
coronary heart disease 16
rheumatoid arthritis 16
hypothyroidism 16
anemia 15
HIV 15
chronic renal failure 15
iron overload 15
hepatitis 15
Evans 15
squamous cell carcinoma 15
vascular disease 15
liver cancer 15
inflammatory bowel disease 14
glioma 14
liver fibrosis 14
gastric cancer 14
gastric ulcer 14
Huntington's disease 14
diabetic retinopathy 13
tardive dyskinesia 13
multiple sclerosis 13
SEM 13
Infection 13
infertility 13
HSP 13
malaria 13
pulmonary edema 13
Down syndrome 12
hyperthyroidism 12
osteoporosis 12
hyperinsulinemia 11
pulmonary hypertension 11
glucose intolerance 11
bronchopulmonary dysplasia 11
liver cancer 11
cirrhosis 11
heart disease 11
virus infection 11
neuropathy 11
ash 11
gestational diabetes mellitus 11
glomerulosclerosis 10
leishmaniasis 10
glioblastoma 10
renal ischemia 10
ulcerative colitis 10
lung disease 10
brain edema 10
metastases 10
Placenta 10
arthritis 10
renal failure 10
parkinsonism 10
idiopathic pulmonary fibrosis 10
immunodeficiency 10
chronic disease 9
acute pancreatitis 9
blindness 9
pneumonia 9
osteoarthritis 9
polycystic ovary syndrome 9
testicular dysfunction 9
ICP 8
Brown 8
sickle cell disease 8
alcoholic fatty liver 8
immunotoxicity 8
metabolic disorder 8
oral cancer 8
cholestasis 8
Blocking 8
emphysema 8
muscular atrophy 8
motor neuron disease 7
pancreatic cancer 7
aggressiveness 7
dermatitis 7
ATM 7
bipolar disorder 7
chlorosis 7
acute myeloid leukemia 7
AIN 7
cerebral infarction 7
more...
Symptom
hyperoxia 105
fatigue 25
starvation 22
seizures 21
anesthesia 20
exhaustion 19
pain 17
chills 15
functional recovery 12
collapse 11
overweight 11
acidity 10
weakness 10
diarrhea 10
respiratory distress 9
skin damage 9
acute stress 8
thinning 8
tremor 6
hypothermia 5
ataxia 5
constipation 5
hypercapnia 4
stigma 3
discomfort 3
headache 3
tinnitus 3
cough 3
Anoxia 3
anorexia 3
discomfort 3
erythema 3
memory loss 2
despair 2
angina 2
polyuria 2
numbness 2
hepatomegaly 2
dizziness 2
lethargy 1
emaciation 1
masculinization 1
cachexia 1
body pain 1
flushing 1
Involuntary Movement 1
knee pain 1
spasm 1
myalgia 1
cerebellar ataxia 1
bradykinesia 1
physical appearance 1
hypoproteinemia 1
wheezing 1
loss of equilibrium 1
Catch 1
neurological disability 1
polydipsia 1
twitching 1
chest pain 1
dyspnea 1
chorea 1
nausea and vomiting 1
agitation 1
sneezing 1
back pain 1
Chronic pelvic pain syndrome 1
catatonia 1
arthralgia 1
Subjective tinnitus 1
Stinging 1
HSA 1
incoordination 1
heartburn 1
blurred vision 1
dysarthria 1
ENT 1
Drug
ROS 312
ascorbate 224
vitamin E 157
Glutathione 78
Heme 42
Leaf 28
FAD 28
Vitamin E 28
NADH 27
lysine 25
Dermatol 25
Cardiovasc 22
Ethanol 20
IL-2 17
Monit 16
ZnO 15
citric acid 13
Capsicum 11
ALA 11
caffeine 11
CTX 10
Nephron 10
Angiotensin II 9
Nephron 9
Rutin 9
MAP 8
EE2 8
Nitric Oxide 8
Fluorescein 8
Adriamycin 7
Indomethacin 7
Glycyrrhiza 7
Vitamin A 6
Arsenic trioxide 6
CSF 6
Gel 6
TiO2 6
Simvastatin 5
Epigallocatechin 5
Triclosan 5
Bifidobacterium 5
CCL 4
Spectrum 4
Asthma 4
lactose 4
Ginger 4
Rosiglitazone 4
nitroglycerin 4
MRC 4
Auranofin 4
NBT 4
PCB 4
niacin 3
Levosimendan 3
Furan 3
Emodin 3
EPA 3
Parkin 3
Albumin 3
ETS 3
CaCl2 3
CaCl2 3
CaCl2 3
Emodin 3
Crotonaldehyde 3
Vitamin K 3
ATV 3
Kainic acid 3
Acacia 3
TAT 3
DNase I 3
Parkin 3
CTX 2
HCH 2
CTX 2
Vitamin B 2
ABC 2
DEX 2
Portal 2
TTC 2
Ginseng 2
Asn 2
DMAP 2
Fructose 2
Retinoic acid 2
Gelatin 2
Idoxifene 2
Photofrin 2
SiO2 2
Serum albumin 2
Pilocarpine 2
Sesamol 2
linolenate 2
Growth hormone 2
Cilostazol 2
Propofol 2
Aminoguanidine 2
ZnCl2 2
ICI 2
Reserpine 2
Captopril 2
Growth hormone 2
Alanine 2
Olive oil 2
ZnCl2 2
Camellia oil 2
Histamine 2
IFN-gamma 2
Ramipril 2
Tannic acid 2
Red ginseng 2
balanced salt solution 2
Glutamic acid 2
Dial 2
Areca 2
SMP 1
Amifostine 1
Theophylline 1
DPA 1
TAC 1
Sodium alginate 1
Fulvestrant 1
CDX 1
Methylprednisolone 1
AZT 1
9-THC 1
Inderal 1
Phosphatidylserine 1
Nipradilol 1
Metoclopramide hydrochloride 1
CIA 1
Pramipexole 1
Tricyclazole 1
DEL 1
Kelp 1
CDX 1
Calcium chloride 1
CED 1
Plasmanate 1
Piracetam 1
CTM 1
DMSA 1
NAG 1
Stannous chloride 1
ENT 1
Coral 1
PMPA 1
CDP 1
R-gene 1
NH3 1
Propidium 1
Gluthathione 1
Monensin 1
Valsartan 1
Doxycycline 1
Malonaldehyde 1
THA 1
Kytril 1
Tacrolimus 1
Zebularine 1
more...
Enzyme
superoxide dismutase 3501
catalase 3152
glutathione peroxidase 1935
glutathione reductase 657
peroxidase 650
glutathione S-transferase 351
ascorbate peroxidase 274
caspase-3 204
mitogen-activated protein kinase 191
alanine aminotransferase 185
lactate dehydrogenase 183
aspartate aminotransferase 177
peroxiredoxin 131
thioredoxin reductase 117
glucose-6-phosphate dehydrogenase 101
NADPH oxidase 96
NADPH oxidase 88
NQO1 82
acetylcholinesterase 81
alkaline phosphatase 80
ATPase 76
xanthine oxidase 72
heme oxygenase 63
creatine kinase 57
AST 53
ERK 50
paraoxonase 47
luciferase 47
dehydroascorbate reductase 45
paraoxonase 44
protein kinase 43
complex I 39
caspase-9 39
proteasome 37
NO synthase 36
AMP-activated protein kinase 36
ceruloplasmin 35
protein kinase C 34
lysozyme 32
phospholipid hydroperoxide glutathione peroxidase 31
tyrosinase 31
succinate dehydrogenase 30
citrate synthase 27
gamma-glutamylcysteine synthetase 27
SOR 26
NOS 24
cytochrome oxidase 24
gamma-glutamyl transpeptidase 24
lipase 24
glutamine synthetase 24
PARP 23
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
lipoxygenase 20
cholinesterase 19
phosphatidylinositol 3-kinase 19
acid phosphatase 18
AMPK 18
AMPK 18
isocitrate dehydrogenase 16
aconitase 16
isocitrate dehydrogenase 15
diaphorase 15
ACS 14
carbonic anhydrase 14
ECH 14
trypsin 14
monoamine oxidase 13
caspase-8 13
focal adhesion kinase 13
MEK 12
phospholipase A2 12
deaminase 12
aldehyde dehydrogenase 11
glucokinase 11
tyrosine hydroxylase 11
MPP 11
glucose oxidase 11
glyceraldehyde-3-phosphate dehydrogenase 10
phosphoenolpyruvate carboxykinase 10
diamine oxidase 10
MMP 10
collagenase 10
reverse transcriptase 10
GSK 10
diaphorase 10
PAL 10
ACE 10
phosphoenolpyruvate carboxykinase 9
ornithine decarboxylase 9
phosphoenolpyruvate carboxykinase 9
6-phosphogluconate dehydrogenase 9
6-phosphogluconate dehydrogenase 9
CPR 8
sulfiredoxin 8
RNA polymerase 8
DNA methyltransferase 8
hexokinase 8
aldehyde dehydrogenase 8
calcineurin 8
aldehyde dehydrogenase 8
renin 8
polyamine oxidase 8
glyceraldehyde-3-phosphate dehydrogenase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
alcohol dehydrogenase 8
UDP-glucuronosyltransferase 7
disulfide reductase 7
chitinase 7
P-glycoprotein 7
transcriptase 7
lipoprotein lipase 7
glyceraldehyde-3-phosphate dehydrogenase 7
glucose-6-phosphatase 7
malate dehydrogenase 7
delta-aminolevulinic acid dehydratase 7
TOR 7
HSD 7
cholesterol acyltransferase 6
MsrA 6
invertase 6
TdT 6
phosphodiesterase 6
phosphofructokinase 6
chalcone synthase 6
NADPH-diaphorase 6
NADH dehydrogenase 6
S-adenosylmethionine decarboxylase 5
PAL 5
demethylase 5
guanylate cyclase 5
glyceraldehyde-3-phosphate dehydrogenase 5
beta-galactosidase 5
cysteine synthase 5
phosphoenolpyruvate carboxylase 5
urease 5
DCF 5
nitrite reductase 5
pepsin 5
nitrite reductase 5
nitrite reductase 5
urease 5
arginase 5
glyceraldehyde-3-phosphate dehydrogenase 5
rubisco 4
methionine sulfoxide reductase 4
pectin methylesterase 4
proline oxidase 4
ATP synthase 4
glutamate synthase 4
laccase 4
3-hydroxyacyl-CoA dehydrogenase 4
TSA 4
papain 4
pyruvate kinase 4
more...
Compound
oxygen 2217
GSH 1100
GSH 1100
water 750
DNA 707
hydrogen 680
Dec 594
CAT 413
CAT 413
CAT 413
glucose 389
H2O2 362
nitric oxide 355
copper 298
MDA 294
selenium 284
zinc 257
sodium 230
proline 224
cadmium 224
salt 213
TNF 209
nitrogen 209
iron 199
cysteine 186
GSSG 159
Clin 158
calcium 153
ethanol 151
NADPH 143
NADPH 143
creatinine 132
urea 127
manganese 121
phosphate 114
ATP 97
superoxide radical 97
acetate 96
Melatonin 86
Malondialdehyde 84
MTT 72
arginine 71
N-acetylcysteine 68
PEG 68
galactose 64
CO2 64
nitrate 60
DPPH 59
glutamate 59
sulfate 55
acetic acid 55
salicylic acid 54
potassium 51
8-OHdG 51
nicotinamide 51
NAD 50
Salt 49
chromium 47
NAD 47
methionine 46
alanine 46
Ascorbic acid 45
Heme 44
CCl4 40
tyrosine 38
NADP 38
Curcumin 37
PEG 37
silver 36
ammonia 34
gallic acid 34
aluminum 34
Gly 34
lysine 33
STZ 33
Vitamin E 33
mercury 33
ABA 33
Lead 32
diacetate 31
alloxan 31
ammonium 31
Thioredoxin 30
Adriamycin 30
Insulin 29
bromide 29
tert-butyl hydroperoxide 28
His 28
FAD 28
silicon 27
NADH 27
pyridine 27
ABA 27
methanol 26
Arsenic 26
pyrene 25
ALP 25
iodine 25
leucine 24
ADR 24
homocysteine 24
serine 24
ethyl acetate 23
Quercetin 23
threonine 23
Phe 23
cyanide 23
nickel 22
DDP 22
dUTP 21
phenol 21
Cardiol 21
cobalt 21
ADP 20
Thiobarbituric acid 19
H2S 19
Panam 19
Resveratrol 19
betaine 19
glutamine 18
MPTP 18
SDS 18
retinol 18
phosphorus 18
aldehyde 18
pentose 17
2-nonenal 17
TOF 17
DHA 17
titanium 17
pentose 16
pentose 16
pentose 16
cAMP 16
ADP 16
NH2 16
ADP 16
tin 15
GABA 15
tryptophan 15
oxalate 14
Asp 14
anthracene 14
valine 14
DMSO 14
tryptophan 14
ACS 14
ACS 14
APAP 14
CdCl2 14
glycerol 13
L-carnitine 13
DHA 13
tryptophan 13
GABA 13
tryptophan 13
aldehyde 13
DHA 13
H2S 12
EDTA 12
more...