Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P30044 (
antioxidant enzyme
)
8,037
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A nucleoside diphosphate kinase-1-disrupted (ndk-1(
RIP-1
)) mutant was observed to be defective in aerial hyphal and conidial development. In this study, two types of hyphae, fine and thick, were observed in wild-type (Wt) strains. However, only fine-type hyphae were observed in the ndk-1(
RIP-1
) mutants. The ndk-1(
RIP-1
) mutants were stimulated by oxidative stress and constitutively expressed an
antioxidant enzyme
catalase (CAT)-3. Furthermore the ndk-1(
RIP-1
) mutants could form thick hyphae by oxidative stress and a disruption of cat-3. These results suggest that the loss of thick hyphae in the ndk-1(
RIP-1
) mutants may be caused by the over-expression of cat-3.
...
PMID:Nucleoside diphosphate kinase-1 regulates hyphal development via the transcriptional regulation of catalase in Neurospora crassa. 1976 88
