Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UNIPROT:P30044 (
antioxidant enzyme
)
8,037
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Phosphoinositide 3-kinase
(
PI3K
) plays a vital role in plant response to abiotic stress. However, the role of
PI3K
in plant immunity is largely unknown. This study showed that
PI3K
enhanced
Arabidopsis
resistance to
Pseudomonas syringae
pv
tomato
DC3000 (
Pst
DC3000) and
Pst
DC3000 (
avrRpt2
). Overexpression of
AtVPS34
promoted stomatal closure while
PI3K
inhibitors blocked that after spray inoculation. Additionally, gene expression of
AtVPS34
was increased upon infection by
Pst
DC3000 (
avrRpt2
), and SA upregulated
AtVPS34
gene expression in this process. Furthermore, overexpression of
AtVPS34
enhanced
PR
gene expression after syringe infiltration with
Pst
DC3000 (
avrRpt2
), while
PI3K
inhibitors inhibited that. The production of hydrogen peroxide and the expression of gene encoding
antioxidant enzyme
were both enhanced in
AtVPS34
overexpressing lines after spray inoculation or syringe infiltration with
Pst
DC3000 (
avrRpt2
). Collectively, these results unraveled a novel and broad role of
PI3K
in plant immunity which promoted stomatal closure and
PR
gene expression possibly
via
regulating ROS production.
...
PMID:Phosphoinositide 3-Kinase Promotes Oxidative Burst, Stomatal Closure and Plant Immunity in Bacterial Invasion. 3211 34
