Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UNIPROT:P21817 (RyR1)
 1,154 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
RyR1 1154
ryanodine receptor 417
RyR2 213
RyR3 132
RYR1 124
dihydropyridine receptor 106
calmodulin 79
Sep 76
Mol 74
cardiac muscle 69
endoplasmic reticulum 68
FKBP12 63
ATP 55
calcineurin 47
FK506 42
DHPR 35
ATPase 33
calcium channel 28
triadin 24
SERCA1 22
Gen 20
FK506-binding protein 18
HEK 16
fused 16
IP3R 15
FKBP 14
microsomal 13
NMR 12
PKA 12
junctin 10
STIM1 10
Cav1.1 10
CACNA1S 10
L-type calcium channel 10
AMP 9
S100A1 9
muscle specific 8
phosphatase 8
non-muscle 8
calpain 8
RYR2 8
IP3R1 7
NER 7
insulin 7
ASI 7
RAD51 7
SERCA2 7
prolyl isomerase 6
GST 6
glutathione transferase 6
SPRY2 6
glutathione S-transferase 6
SDS 6
MRI 6
BRCA1 6
MTM1 6
polypeptide 6
TRPC3 6
myotubularin 6
GSH 6
SEPN1 6
CCD 5
creatine kinase 5
TRPC1 5
BRCA2 5
ROS 5
FK506-binding protein 12 5
CRAC 5
dystrophin 5
IP3R2 5
phospholamban 5
NOX4 5
DM1 5
caspase-3 5
TOF 5
myosin heavy chain 5
PARP 5
Triadin 5
Ca2+-ATPase 5
STAC3 5
more...
Disease
malignant hyperthermia 172
myopathy 77
heart failure 31
cancer 26
Central core disease 26
hypertension 14
diabetes 12
tumor 11
depression 10
centronuclear myopathy 9
cold 9
DM1 8
multicore 7
stroke 6
aggression 6
GSH 6
scoliosis 6
SDS 6
periodic paralysis 5
CCD 5
myocardial infarction 5
ischemia 5
prolapse 5
coronary artery disease 5
CCD 5
Duchenne muscular dystrophy 4
muscular dystrophy 4
porcine stress syndrome 4
obesity 4
cardiovascular disease 4
cardiomyopathy 4
Alzheimer's disease 4
respiratory failure 4
tetanus 4
SEM 4
prostate cancer 4
mole 3
heart disease 3
tumor progression 3
dysplasia 3
schizophrenia 3
myasthenia gravis 3
akinesia 3
nystagmus 3
neuromuscular disorder 3
PCP 3
Epstein 3
muscular atrophy 3
thymoma 3
ARVD 3
mole 3
CIE 3
lung cancer 2
breast cancer 2
migraine 2
Still 2
XPG 2
pulmonary hypertension 2
Lambert-Eaton myasthenic syndrome 2
aggressiveness 2
sepsis 2
lung carcinoma 2
brucellosis 2
strabismus 2
terminal disease 2
anemia 2
preeclampsia 2
status epilepticus 2
mental retardation 2
mental retardation 2
congestive heart failure 2
bone metastases 2
insulinoma 2
ARVD2 2
glaucoma 2
Catecholaminergic polymorphic ventricular tachycardia 2
uterus 2
achromatopsia 2
hypertrophic cardiomyopathy 2
fits 2
more...
Symptom
weakness 57
anesthesia 22
fatigue 19
ophthalmoplegia 14
hypotonia 13
pain 7
muscle rigidity 4
cachexia 3
exhaustion 3
myalgia 3
seizures 2
respiratory distress 2
photophobia 2
dyspnea 2
hypothermia 2
muscle stiffness 2
collapse 2
low back pain 2
analgesia 1
starvation 1
overweight 1
ataxia 1
chest pain 1
chills 1
asynergy 1
diarrhea 1
blurred vision 1
neck pain 1
nausea 1
thinning 1
HSA 1
paresis 1
headache 1
impaired motor coordination 1
Drug
caffeine 164
Cardiovasc 9
Vitamin A 7
Asn 5
ROS 5
DM1 5
K201 3
PCP 3
lysine 3
CPM 3
ABC 2
RFP 2
Triclosan 2
CaCl2 2
Alanine 2
PCB 2
all-trans-retinol 2
CaCl2 2
CaCl2 2
Spectrum 2
CoCl2 1
CTX 1
Dantrolene sodium 1
vitamin E 1
Saha 1
IL-2 1
Retinoic acid 1
CoCl2 1
RbCl 1
RbCl 1
Angiotensin II 1
Nephron 1
CTC 1
Fragment 1
nitroglycerin 1
Gel 1
CAM 1
VCR 1
Arsenic trioxide 1
NAG 1
Forskolin 1
EE2 1
CTC 1
Glutathione 1
ascorbate 1
Dermatol 1
EDR 1
Leaf 1
BLM 1
Enzyme
dihydropteridine reductase 35
ATPase 33
protein kinase 21
calcineurin 15
glutathione S-transferase 14
protein kinase C 6
PARP 6
trypsin 5
creatine kinase 5
AMPK 4
renin 4
cathepsin L 4
AMP-activated protein kinase 3
endonuclease 3
NADPH oxidase 3
RNase 3
calcium pump 3
PCP 3
caspase-3 3
CPM 3
RNase 3
reverse transcriptase 3
phospholipase C 3
NADPH oxidase 3
mitogen-activated protein kinase 3
protein phosphatase 2A 2
phosphodiesterase 2
ERK 2
catalase 2
NO synthase 2
ACS 2
NOS 2
acid phosphatase 2
acetylcholinesterase 2
CPT 2
lactate dehydrogenase 2
citrate synthase 1
m-calpain 1
acyl-CoA dehydrogenase 1
chloramphenicol acetyltransferase 1
S1 nuclease 1
calpain 3 1
ATP synthase 1
aequorin 1
TSR 1
complex I 1
adenosine deaminase 1
glyceraldehyde-3-phosphate dehydrogenase 1
phosphatidylinositol 3-kinase 1
MIP 1
ribonuclease 1
caspase-9 1
adenosine deaminase 1
enolase 1
proteasome 1
glyceraldehyde-3-phosphate dehydrogenase 1
succinate dehydrogenase 1
topoisomerase 1
carboxypeptidase A 1
CCS 1
AMPK 1
lipoprotein lipase 1
CAD 1
peroxidase 1
cathepsin D 1
aldolase 1
superoxide dismutase 1
CAD 1
topoisomerase 1
CAD 1
tyrosine hydroxylase 1
pyruvate kinase 1
hexokinase 1
CaMKII 1
PDK1 1
ribonuclease 1
inositol phosphatase 1
choline acetyltransferase 1
mu-calpain 1
adenosine kinase 1
more...
Compound
calcium 496
caffeine 164
Ryanodine 102
Dec 83
DNA 71
ATP 55
oxygen 52
FK506 42
m-cresol 29
Mg2+ 27
cysteine 24
alanine 21
arginine 19
Dantrolene 18
sodium 18
Clin 18
water 15
threonine 14
nitric oxide 13
lysine 12
leucine 12
glutamate 11
potassium 10
nitrogen 10
phosphate 10
His 9
salt 9
retinol 9
AMP 9
glucose 9
CO2 9
Cardiol 9
Gly 8
GSH 7
tyrosine 7
Vitamin A 7
Ile 7
GSH 7
Asp 7
ADP-ribose 7
serine 6
retinoic acid 6
SDS 6
NH2 6
sulfate 6
CHAPS 6
pyrene 5
TOF 5
MHS 5
methionine 5
Ins(1,4,5)P3 4
tryptophan 4
Nicotinic acid adenine dinucleotide phosphate 4
cAMP 4
Ruthenium 4
Phe 4
hydrogen 4
tryptophan 4
Ruthenium 4
ADP 4
ADP 4
ADP 4
1-propanesulfonic acid 3
N-acetylcysteine 3
aldehyde 3
ethanol 3
PCP 3
aldehyde 3
fluorine 3
Austin 3
selenium 3
tryptophan 3
hydroxide 3
NAD 3
manganese 3
tryptophan 3
TDT 3
MAK 3
nickel 3
asparagine 3
more...